Diagnostic Evaluation of Hereditary Hemochromatosis (HFE and Non-HFE)
Keywords: Hemochromatosis; Hepcidin; HFE; TFR2; Hemojuvelin; Ferroportin; Phlebotomy;
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Original ResearchFull Report: Basic and Translational-LiverHeme Exporter FLVCR1a Regulates Heme Synthesis and Degradation and Controls Activity of Cytochromes P450
Keywords: ALAS1; CYP; Flvcr; HO-1; Flvcr1; ALA; 5-aminolevulinic acid; ALAS; 5-aminolevulinic acid synthase; Be(a)P; benzo(a)pyrene; CYP; cytochrome P450; FLVCR1a; feline leukemia virus subgroup C cellular receptor 1a; Fpn; ferroportin; HO; heme oxygenase; mRNA; me
Neutrophil gelatinase-associated lipocalin and interleukin-10 regulate intramacrophage Chlamydia pneumoniae replication by modulating intracellular iron homeostasis
Keywords: aIL-10; anti-interleukin-10; C. pneumoniae, Cpn; Chlamydia pneumoniae; DMT-1; divalent metal transporter-1; Fe; iron; Fpn1; ferroportin; hamp; hepcidin; HPRT; hypoxanthine guanine phosphoribosyl transferase; Lcn-2; Lipocalin-2; IL-10; interleukin-10; TfR;
Dietary fat level affects tissue iron levels but not the iron regulatory gene HAMP in rats
Keywords: DMT1; divalent metal transporter 1; C/EBPα; CCAAT/enhancer binding protein α; FPN; ferroportin; HAMP; human antimicrobial peptide; Hb; hemoglobin; Hct; hematocrit; HF; high fat; HFE; hemochromatosis protein; HJV; hemojuvelin; IRE; iron-responsive elemen
Mammalian iron transporters: Families SLC11 and SLC40
Keywords: Nramp1; natural resistance-associated macrophage protein-1; DMT1; divalent metal transporter-1; DCT1; divalent cation transporter-1; Nramp2; natural resistance-associated macrophage protein-2; Ireg1; iron regulated-transporter-1; MTP1; metal transporter p
Ferroportin Q248H mutation, hyperferritinemia and atypical type 2 diabetes mellitus in South Kivu
Keywords: Ferroportin; Hyperferritinemia; Diabetes; Mellitus; South Kivu
Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice
Keywords: Ferroportin; Hypoxia; Anemia; Transcription
Les hémochromatoses
Keywords: Surcharge en fer; hémochromatose; transferrine; ferritine; fer non lié Ã la transferrine; hepcidine; hémojuvéline; récepteur de la transferrine de type 2; ferroportine; céruloplasmine; Iron overload; hemochromatosis; transferring; ferritin; non-tra
Iron repletion relocalizes hephaestin to a proximal basolateral compartment in polarized MDCK and Caco2 cells
Keywords: apo-Tf, apotransferrin; holo-Tf, holotransferrin; Heph, hephaestin; Cp, ceruloplasmin; DMT1, divalent metal transporter 1; FPN, ferroportinCopper; Iron; Hephaestin; Ferroportin; Apo-transferrin; Holo-transferrin; Enterocytes
The iron transporter ferroportin can also function as a manganese exporter
Keywords: DMT1; divalent metal transporter-1/NRAMP2; FPN1; ferroportin/SLC40A1; Ferroportin; FPN1; Manganese; Metal export; Divalent metal transporter; Xenopus laevis oocytes;
Protein degradation and iron homeostasis
Keywords: F-box and Leucine-rich Repeat Protein 5; Hemerythrin domain; Iron homeostasis; Iron Regulatory Proteins; Ferroportin; Hypoxia Inducible Factor
Ferroportin-mediated iron transport: Expression and regulation
Keywords: Ceruloplasmin; Ferroportin; Hepcidin; Homeostasis; Internalization; Iron
Non-transferrin bound iron: A key role in iron overload and iron toxicity
Keywords: Non-transferrin bound iron (NTBI); Hepcidin; Ferroportin; Iron overload; Hemochromatosis; Thalassemia;
Hereditary hemochromatosis and transferrin receptor 2
Keywords: TfR2; HFE; Hepcidin; Hemojuvelin; BMP; Ferroportin;
Trastornos del metabolismo del hierro y anemia ferropénica
Keywords: Hepcidina; Ferroportina; Anemia ferropénica; HemocromatosisHepcidin; Ferroportin; Iron deficiency anemia; Hemochromatosis
L'hepcidine : état actuel de nos connaissances
Keywords: Fer; ferritine; ferroportine; hepcidine; protéine HFE; transferrine; hémochromatose; Iron; ferritin; ferroportin; HFE protein; trasnferrin; hémochromatosis;
Haemochromatosis
Keywords: ferroportin; haemochromatosis; hepcidin; HFE; iron; liver
Transport of hepcidin, an iron-regulatory peptide hormone, into retinal pigment epithelial cells via oligopeptide transporters and its relevance to iron homeostasis
Keywords: RPE, retinal pigment epithelium; SOPT, sodium-coupled oligopeptide transporter; deltorphin II, Tyr-D-Ala-Phe-Glu-Val-Val-Gly; DADLE, Tyr-D-Ala-Gly-Phe-D-LeuOligopeptide transporters; Hepcidin; Retinal pigment epithelium; Iron homeostasis; Ferroportin
Gastrins, iron homeostasis and colorectal cancer
Keywords: CCK; cholecystokinin; CRC; colorectal carcinoma; Dcytb; a duodenal cytochrome b-like ferric reductase; DMT-1; divalent metal transporter 1; ECL; enterochromaffin-like; Fpn; ferroportin; Ggly; glycine-extended gastrin17; Gamide; amidated gastrin17; HFE; th
ReviewHepcidin in human iron disorders: Therapeutic implications
Keywords: HC; hemochromatosis; TfR2; transferrin receptor 2; HAMP; hepcidin gene; HJV; hemojuvelin; Tf; transferrin; FPN; ferroportin; LEAP-1; liver expressed antimicrobial protein; BMPs; bone morphogenetic proteins; RGMs; repulsive guidance molecules; RGMs; transm
Interactions Between Ferroportin and Hephaestin in Rat Enterocytes Are Reduced After Iron Ingestion
Keywords: Intestine; Duodenal Epithelium; Ferroportin Topology; Ferroportin and Hephaestin Interaction; Anti-Fpn C; anti-Fpn C-terminus; Anti-Fpn 172; anti-Fpn 172-193; Anti-Fpn 232; anti-Fpn 232-249; Anti-Fpn 370; anti-Fpn 370-420; BLM; basolateral membrane; BN; b
Sex and Acquired Cofactors Determine Phenotypes of Ferroportin Disease
Keywords: Hemochromatosis; Iron Overload; Genetic Disease; Family Study; BMI; body mass index; FPN; ferroportin; HIC; hepatic iron concentration; HJV; hemojuvelin; N; normal; TFR2; transferrin receptor 2; WT; wild type;
Intestinal DMT1 Cotransporter Is Down-regulated by Hepcidin via Proteasome Internalization and Degradation
Keywords: Proteolysis; Iron Overload; Hepcidin; Hemochromatosis; FPN; ferroportin; GFP; green fluorescent protein; HBSS; Hank's balance salt solution; HIF; hypoxia-inducible factor; IL-6; Interleukin-6; IRE; iron-responsive element; mRNA; messenger RNA; PBS; phosph
Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-α and macrophage migration inhibitory factor concentrations in African children
Keywords: Ferroportin; SLC40A1; Tumor necrosis factor; Iron; African children
Genistein up-regulates the iron efflux system in glial cells
Keywords: Astrocyte; Ceruloplasmin; Ferroportin; Genistein; Iron
Interleukin-1β induces ceruloplasmin and ferroportin-1 gene expression via MAP kinases and C/EBPβ, AP-1, and NF-κB activation
Keywords: Astrocyte; Ceruloplasmin; Ferroportin; Interleukin-1β; Iron;
Pantothenate kinase-2 (Pank2) silencing causes cell growth reduction, cell-specific ferroportin upregulation and iron deregulation
Keywords: Pantothenate kinase; Ferroportin; Iron metabolism; Ferritin; Neurodegeneration with brain iron accumulation
Research ArticleIron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis
Keywords: Transferrin receptor 2; Iron transport; Haemochromatosis; Iron overload; Liver; TFR; transferrin receptor; IRE; iron regulatory element; HJV; haemojuvelin; BMP; bone morphogenetic protein; FPN; ferroportin; HH; hereditary haemochromatosis; Hamp; hepcidin;
Surcharges héréditaires en fer
Keywords: Surcharge en fer; Hémochromatose; HFE; Hepcidine; Ferroportine; Hémojuvéline; Fer non lié à la transferrineIron overload; Haemochromatosis; HFE; Hepcidin; Ferroportin; Haemojuvelin; Transferrin receptor; Non-transferrin bound iron
Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin
Keywords: Aceruloplasminemia; Ceruloplasmin; Ferroportin; Haemochromatosis; Hepcidin;
Métallation réversible d'un analogue bis-disulfure du site de liaison Cys*-X-Cys* de l'hepcidine : caractérisation structurale du complexe de cuivre associé
Keywords: Métabolisme du fer; Hepcidine; Ferroportine; Bis-disulfure cyclique; Complexe du cuivre (III); Iron metabolism; Hepcidin; Ferroportin; Cyclic bis-disulfide; Cu(III);
Iron delocalisation in the pathogenesis of malarial anaemia
Keywords: Malaria; Anaemia; Macrophage; Iron; Ferroportin; Hepcidin;
Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment
Keywords: Iron Metabolism; Hereditary Disorders; Micronutrients; Hepcidin; HFE; BMP; bone morphogenic protein; FPN; ferroportin; HAMP; hepcidin gene; HJV; hemojuvelin; RGM; repulsive guidance molecule; TfR; transferrin receptor; TS; transferrin saturation;
Systemic iron status
Keywords: Iron deficiency; Ferritin; Ferroportin; DMT1; Iron status; Iron homeostasis
Papel de la hepcidina en la patogenia de la hemocromatosis
Keywords: Hepcidina; Hemocromatosis; Absorción de hierro; Ferroportina; Hepcidin; Hemochromatosis; Iron absorption; Ferroportin;
Quantitative analysis of iron concentration and expression of ferroportin 1 in the cortex and hippocampus of rats induced by cerebral ischemia
Keywords: Brain; Ferroportin; Iron; Ischemia
Brain and retinal ferroportin 1 dysregulation in polycythaemia mice
Keywords: Polycythaemia; Ferroportin; Brain; Retina; Iron
Iron metabolism in the anemia of chronic disease
Keywords: Macrophage; Hepcidin; Ferroportin; Iron restriction; Infection; Cytokine
Cellular iron transport
Keywords: Divalent metal transporter (DMT1); Ferroportin; Transferrin; Ferric reductase; Iron responsive element (IRE); Iron regulatory protein (IRP)
Hepatic iron concentration, fibrosis and response to venesection associated with the A77D and V162del “loss of function” mutations in ferroportin disease
Keywords: Ferroportin; Hemochromatosis; Hepatic iron concentration; Fibrosis; Venesection
Modulation of macrophage iron transport by Nramp1 (Slc11a1)
Keywords: Dmt1; Ferroportin; Transferrin; iNOS; Iron; Nitric oxide; Nramp1Dmt1, divalent metal transporter 1; Fpn1, ferroportin 1; iNOS, inducible nitric oxide synthase; IRE, iron responsive element; IRP, iron regulatory protein; NO, nitric oxide; Nramp1, natural r
Analysis of SLC40A1 gene at the mRNA level reveals rapidly the causative mutations in patients with hereditary hemochromatosis type IV
Keywords: Ferroportin; Hemochromatosis; NIRCA; RT-PCR; SLC40A1
Case reportClinical, pathological, and molecular correlates in ferroportin disease: A study of two novel mutations
Keywords: Iron overload; Ferroportin; Hemochromatosis; Hepcidin; Zebrafish;
Molecular evolution and characterization of hepcidin gene products in vertebrates
Keywords: AMP, antimicrobial peptide; HAMP, hepcidin; EST, expressed sequence tag; HTGS, high throughput genomic sequences; TFR, transferrin receptor; NJ, neighbor joiningAntimicrobial peptides; Iron homeostasis; Innate defense; Ferroportin; Fish
Ferroportin: Lack of evidence for multimers
Keywords: Ferroportin; Dominant inheritance; Monomer; BRET; Hemochromatosis
Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload
Keywords: DHIO; Dysmetabolic Hepatic Iron Overload; TfR; Transferrin Receptor; BMP; bone morphogenetic protein; NAFLD; Non-Alcoholic Fatty Liver Disease; HFE-HH; HFE-hemochromatosis; FP; ferroportin; HIS; Hepatocyte Iron Score; SIS; Sinusoidal Iron Score; PIS; Port
Current approach to hemochromatosis
Keywords: Hemochromatosis; Iron overload; HFE; Hepcidin; Hemojuvelin; Ferroportin; Transferrin receptor 2; Transferrin; Saturation ferritin; Venesection
SLC40A1 Q248H allele frequencies and Q248H-associated risk of non-HFE iron overload in persons of sub-Saharan African descent
Keywords: Ferroportin; Genetics; Hemojuvelin A310G; Mutation
A novel mutation in ferroportin implicated in iron overload
Keywords: Iron overload; Ferroportin; Autosomal dominant; Mutation detection; Real-time PCR
STAT3 Is Required for IL-6-gp130-Dependent Activation of Hepcidin In Vivo
Keywords: FPN; ferroportin; IL; interleukin; KI; knockin; KO; knockout; PCR; polymerase chain reaction; SAA; serum amyloid A; SOCS3; suppressor of cytokine signaling 3; UV; ultraviolet; WT; wild-type;