AMP-activated kinase is a regulator of fibroblast growth factor 23 production
Keywords: calcium; FGF23; Klotho; Orai1; phosphate; parathyroid hormone;
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Plasma FGF23 is not elevated in prostate cancer
Keywords: FGF23; Prostate cancer; PSA; Kidney function;
Synergistic effect of 1α,25-dihydroxyvitamin D3 and 17β-estradiol on osteoblast differentiation of pediatric MSCs
Keywords: 1α,25(OH)2D; 1α,25-dihydroxy vitamin D; 25(OH)D; 25-hydroxyvitamin D; AR; androgen receptor; BMI; body mass index; CYP; cytochrome P450; DBP; vitamin D binding protein; ER; estrogen receptor; FGF23; fibroblast growth factor 23; hMSC; human marrow stroma
Phosphaturic mesenchymal tumor without osteomalacia: additional confirmation of the “nonphosphaturic” variant, with emphasis on the roles of FGF23 chromogenic in situ hybridization and FN1-FGFR1 fluorescence in situ hybridization
Keywords: Phosphaturic mesenchymal tumor; Nonphosphaturic; FGF23; FN1-FGFR1; Tumor-induced osteomalacia (TIO);
The impact of VDR expression and regulation in vivo
Keywords: 1,25(OH)2D3; 1,25 dihydroxyvitamin D3; atRA; all trans retinoic acid; BMD; bone mineral density; db-cAMP; dibutyryl cyclic AMP; ChIP; chromatin immunoprecipitation; ChIP-chip; ChIP followed by microarray; ChIP-seq; ChIP followed by sequencing; FGF23; fibr
The 24,25 to 25-hydroxyvitamin D ratio and fracture risk in older adults: The cardiovascular health study
Keywords: 25(OH)D; 25 hydroxyvitamin D; 24,25(OH)2D; 24,25-dihydroxyvitmin D; 1,25(OH)2D; 1,25-dihydroxyvitamin D; The vitamin D metabolite ratio (VMR); Ratio of 24,25(OH)2D to 25(OH)D; VDR; Vitamin D Receptor; DBP; Vitamin D Binding Protein; CHS; Cardiovascular He
Role of kinase-coupled TRP channels in mineral homeostasis
Keywords: AC; acylcarnitines; ALPase; alkaline phosphatase; ALS-G; amyotrophic lateral sclerosis; ARE; antioxidant response elements; CC domain; coiled-coil domain; CPT; carnitine palmitoyltransferases; CS; corpuscles of Stannius; GPCR; G protein-coupled receptor;
Comparison of the effects of novel vitamin D receptor analog VS-105 and paricalcitol on chronic kidney disease-mineral bone disorder in an experimental model of chronic kidney disease
Keywords: VS-105; Vitamin D analog; CKD-MBD; FGF23; Klotho;
The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression
Keywords: FGF23; Phosphate; Hypoxia inducible factor-1α; X-linked hypophosphatemia;
Quel pourrait être le futur de la prise en charge de la maladie rénale chronique en nutrition ?
Keywords: Restriction protéique; Insuline; Urée; Phosphore; FGF23; Microbiote intestinal; Dialyse incrémentale; Score nutritionnel; Protein restriction; Insulin; Urea; Phosphorus; FGF23; Gut microbiota; Incremental haemodialysis; Nutritional score;
Stratégies visant à réduire la phosphatémie dans la maladie rénale chronique
Keywords: Phosphate; Calcium; Insuffisance rénale chronique; Dialyse; PTH; FGF23; Chélateurs de phosphate; Phosphate; Calcium; Chronic kidney disease; Dialysis; PTH; FGF23; Phosphate binders;
MicroRNA expression in a phosphaturic mesenchymal tumour
Keywords: FGF23; Hypophosphatemia; Tumour; microRNA; Next generation sequencing;
Vascular calcification in CKD-MBD: Roles for phosphate, FGF23, and Klotho
Keywords: CAVD; calcific aortic valve disease; CKD; chronic kidney disease; CKD-MBD; CKD-mineral and bone disorder; ESKD; endstage kidney disease; FGF23; fibroblast growth factor 23; FGFR; fibroblast growth factor receptor; Pi; phosphate; PTH; parathyroid hormone;
Ex vivo construction of human primary 3D-networked osteocytes
Keywords: Human bone tissue model; Human primary osteocytes; Human primary osteoblasts; 3D culture; Microfluidic; Sclerostin; SOST; FGF23;
Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease
Keywords: CKD; FGF23; inflammation; mortality;
Article EMCRachitismes
Keywords: Rachitisme carentiel; Rachitisme vitaminorésistant; Rachitisme hypophosphatémique; Vitamine D; FGF23;
The complexity of chronic kidney disease-mineral and bone disorder across stages of chronic kidney disease
Keywords: bone; chronic kidney disease; FGF23; hemodialysis; hyperparathyroidism; mineral metabolism;
CYP24A1 loss of function: Clinical phenotype of monoallelic and biallelic mutations
Keywords: FGF23; fibroblastic growth factor 23; PTH; parathyroid hormone; WS; Williams syndrome; 1,25-(OH)2D; 1,25-dihydroxyvitamin D; 24,25-(OH)2D; 24,25-dihydroxyvitamin D; 25-OHD; 25-hydroxyvitamin D; 24-hydroxylase; hypercalcemia; hypercalciuria; vitamin D; Wil
Novel functions of circulating Klotho
Keywords: Hyperphosphatemia; Hypophosphatemia; cKL; FGF23; Phosphate; Vascular calcification;
Targeted inhibition of Klotho binding to fibroblast growth factor 23 prevents hypophosphetemia
Keywords: FGFR1; FGF23; Molecular dynamics simulation;
Genetic diseases resulting from disordered FGF23/klotho biology
Keywords: FGF23; Klotho; Hypophosphatemia; Hyperphosphatemia; Tumoral calcinosis; GALNT3; PHEX;
The chronic kidney disease - Mineral bone disorder (CKD-MBD): Advances in pathophysiology
Keywords: CKD-MBD; Activin; Dickkhopf 1; Klotho; FGF23; Parathyroid hormone; Renal osteodystrophy; Vascular calcification;
Etelcalcetide (AMG 416), a peptide agonist of the calcium-sensing receptor, preserved cortical bone structure and bone strength in subtotal nephrectomized rats with established secondary hyperparathyroidism
Keywords: Cortical porosity; Bone turnover; Secondary hyperparathyroidism; FGF23; Calcium-sensing receptor agonist;
FGF23-αKlotho as a paradigm for a kidney-bone network
Keywords: Klotho; FGF23; Chronic kidney disease;
Tissue expression and source of circulating αKlotho
Keywords: Klotho; FGF23; FGF-23;
Multiple Looser zones of osteomalacia in Byler disease with associated vitamin D deficiency, phosphaturia, and elevated FGF23
Keywords: Byler disease; Cholestasis; Looser zones; Osteomalacia; FGF23
Letter to the Editor, concerning: “FGF23-regulated production of fetuin-A (AHSG) in osteocytes”
Keywords: Fetuin-A; AHSG; FGF23; Osteocytes; Plasma protein;
Vitamin D metabolism and regulation in pediatric MSCs
Keywords: 1α,25(OH)2D; 1α,25-dihydroxyvitamin D; 25(OH)D; 25-hydroxyvitamin D; BMI; body mass index; CYP; cytochrome P450; DBP; vitamin D binding protein; ER; estrogen receptor; FGF23; fibroblast growth factor 23; hMSC; human marrow stromal cell, a.k.a. mesenchym
Vitamin D2 supplementation in ICU on subjects with traumatic injuries
Keywords: Vitamin D; Ergocalciferol; Injury; Leptin; FGF23; 25OHD3;
Craniometaphyseal dysplasia with obvious biochemical abnormality and rickets-like features
Keywords: CMD; Craniometaphyseal dysplasia; ANKH; ANKH inorganic pyrophosphate transport, regulator; PPi; Pyrophosphatase; GJA1; Gap junction protein, α 1; PUMCH; Peking Union Medical College Hospital; β-CTX; β C-terminal telopeptide of type I collagen; FGF23; F
The NIH Undiagnosed Diseases Program and Network: Applications to modern medicine
Keywords: ACDC; arterial calcification due to deficiency of CD73; ALP; alkaline phosphatase; DEXA; dual-energy X-ray absorptiometry; FGF23; fibroblast growth factor 23; GALNT3; polypeptide N-acetylgalactosaminyltransferase 3; HPO; Human Phenotype Ontology; IgA; imm
Wound healing delays in α-Klotho-deficient mice that have skin appearance similar to that in aged humans - Study of delayed wound healing mechanism
Keywords: Klotho; Wound healing; FGF23; TNF-α;
Serum fibroblast growth factor 23, serum iron and bone mineral density in premenopausal women
Keywords: Iron; Fibroblast growth factor 23; FGF23; Bone mineral density; DXA; Premenopausal women;
Enfermedad óseo mineral relacionada con la enfermedad renal crónica: Klotho y FGF23; implicaciones cardiovasculares
Keywords: Riesgo cardiovascular; Enfermedad renal crónica; Klotho; FGF23Cardiovascular risk; Chronic kidney disease; Klotho; FGF23
The mechanisms underlying the beneficial effects of exercise on bone remodeling: Roles of bone-derived cytokines and microRNAs
Keywords: Exercise; Bone remodeling; Osteoblast; Osteoclast; Osteocalcin; FGF23; microRNA;
Fibroblast growth factor 23 and markers of mineral metabolism in individuals with preserved renal function
Keywords: calcium; FGF23; phosphate; PTH; TmP/GFR;
Update on FGF23 and Klotho signaling
Keywords: FGF23; Fibroblast growth factor-23; Klotho; Bone; Kidney; Parathyroid gland;
Exercise-stimulated FGF23 promotes exercise performance via controlling the excess reactive oxygen species production and enhancing mitochondrial function in skeletal muscle
Keywords: FGF23; Exercise; Skeletal muscle; PPAR-δ; Mitochondrial functionDCFH, 2',7'-dichlorofluorescein-diacetate; FGF, fibroblast growth factor; PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1α; PPAR-δ, peroxisome proliferator-activated recept
Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition
Keywords: ER; endoplasmic reticulum; CMK; decanoyl RVRR-chloromethyl ketone; PC2; prohormone convertase 2; PC5/6; proprotein convertase 5/6; TGN; trans-Golgi network; FGF23; Posttranslational processing; Proprotein convertase; 7B2; Furin; Osteocyte; PC5/6;
Combined sequence and sequence-structure based methods for analyzing FGF23, CYP24A1 and VDR genes
Keywords: Chronic kidney disease; SNP analysis; Combined sequence and sequence-structure based methods; FGF23; CYP24A1; VDR;
Direct inhibition of osteoblastic Wnt pathway by fibroblast growth factor 23 contributes to bone loss in chronic kidney disease
Keywords: bone; chronic kidney disease; FGF23; hyperparathyroidism; phosphate; uremia;
In vivo evidence for a limited role of proximal tubular Klotho in renal phosphate handling
Keywords: 1,25(OH)2D3; Cre/loxP; Fgf23; mineral metabolism; Npt2a;
The effect of burn on serum concentrations of sclerostin and FGF23
Keywords: Burns; Osteocytes; FGF23; Sclerostin
FGF23 gene variation and its association with phosphate homeostasis and bone mineral density in Finnish children and adolescents
Keywords: Phosphate; FGF23; PTH; Child; Adolescent; Bone morphometry;
Breast milk stimulates growth hormone secretion in infant mice, and phosphorus insufficiency disables this ability and causes dwarfism-like symptoms
Keywords: Low-phosphorus diet; Breast milk; Growth hormone; Dwarfism-like symptoms; FGF23; fibroblast growth factor 23; GH; growth hormone; IGF-1; insulin-like growth factor 1; LPD; low-phosphorus diet; NPD; normal phosphorus diet;
Modulatory effects of l-arginine and soy enriched diet on bone homeostasis abnormalities in streptozotocin-induced diabetic rats
Keywords: ALP; alkaline phosphatase; BMP-2; bone morphogenetic protein 2; CaSR; calcium sensing receptor; CTX; C-terminal telopeptides of type I collagen; DM; diabetes mellitus; Dlx5; distal less gene; EGF; epidermal growth factor; ERβ; estrogen receptor β; FGF23
Vitamin D and its receptor during late development
Keywords: Vitamin D; Calcium; 1,25(OH)2D/VDR system; PTH; FGF23; c-MYC;
Janus kinase 3 regulates renal 25-hydroxyvitamin D 1α-hydroxylase expression, calcitriol formation, and phosphate metabolism
Keywords: 1,25(OH)2D3; FGF23; intestinal phosphate absorption; Janus kinase 3; phosphaturia;
SPR4-peptide alters bone metabolism of normal and HYP mice
Keywords: Rickets; MEPE; DMP1; FGF23; PHEX; Sclerostin
Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli
Keywords: FGF23; TNF; TWEAK; IL-1; LPS; Pro-inflammatory cytokines