Keywords: APOA1; apolipoprotein A1; ASCL2; Achaete-Scute Family BHLH Transcription Factor 2; CDX2; caudal type homeobox 2; CIDR; controlled intravaginal drug release device; CL; corpora lutea; DNMT(13a/b); DNA methylatransferase; DOHAD; developmental origins of adu
مقالات ISI (ترجمه نشده)
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Keywords: Apert syndrome; Genetic disorder; Craniosynostosis; FGFR2;
Keywords: Craniofacial phenomics; Craniosynostosis; FGFR2; Maxilla; Mandible; Tooth;
Keywords: FGFR2; fibroblast growth factor receptor gene 2; FGFR3; fibroblast growth factor receptor gene 3; TWIST1; twist family bHLH transcription factor 1; EFNB1; ephrin B1; WES; whole exome sequencing; 3D-CT; three-dimensional computed tomography; SNPs; single
Keywords: 25(OH)D; 25-hydroxyvitamin D; BMD; bone mineral density; BMI; body mass index; CLEC2B; C-type lectin domain family 2 member B; CRH; corticotropin-releasing hormone; CVs; coefficients of variation; DEGs; differentially expressed genes; FBS; fetal bovine se
Keywords: DC; dendritic cell; PD-L2; programmed cell death ligand 2; SASA; solvent-accessible surface area; FGFR2; fibroblast growth factor receptor 2; LPS; lipopolysaccharide; GST; glutathione S-transferase; PEG; polyethylene glycol; X-ray crystallography; V-set I
Keywords: Gastric cancer; Esophagogastric junction cancer; Gastroesophageal adenocarcinoma; HER2; VEGFR2; EGFR; MET; FGFR2;
Keywords: FGFR2; HER2; ERBB2; ROS1; Tyrosine kinase; Targeted therapy; Bile;
Keywords: FAK; FGFR2; Inhibitor; Angiogenesis; Cancer;
Low-level clonal FGFR2 amplification defines a unique molecular subtype of intrahepatic cholangiocarcinoma in a Chinese population
Keywords: FGFR2; Low-level clonal amplification; Intrahepatic cholangiocarcinoma;
Inactivation of Fgfr2 gene in mouse secondary palate mesenchymal cells leads to cleft palate
Keywords: Secondary palate; Fgfr2; Palate initiation; Cleft palate;
Transcriptome analysis identifies genes involved in sex determination and development of Xenopus laevis gonads
Keywords: Amh; Anti-Müllerian hormone; Bmp4; Bone morphogenetic protein 4; Dax1; Dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1; Dhh; Desert hedgehog; Dmrt1; Doublesex and mab-3 related transcription factor 1; DM-W; W-li
Meeting report for Odd Pols 2016: Ann Arbor 2.0
Keywords: FGFR2; FGF Receptor-2; hESCs; human embryonic stem cells; lncRNAs; long noncoding RNAs; NORs; Nucleolus Organizer Regions; RdDM; RNA-directed DNA Methylation; Pol I; RNA polymerase I; Pol II; RNA polymerase II; Pol III; RNA polymerase III; Pol IV; RNA pol
Apert syndrome with S252W FGFR2 mutation and characterization using Phenomizer: An Indian case report
Keywords: FGFR; fibroblast growth factor receptor; BKT; Binet Kamat intelligence test; ADHD; attention deficit hyperactivity disorder; Craniosynostosis; Apert syndrome; FGFR2; Phenomizer; Genetic diagnosis;
Ectopic expression of FGF5s induces wool growth in Chinese merino sheep
Keywords: FGF5; The fibroblast growth factor 5 gene; FGF5s; Fibroblast growth factor 5-short; FGF; The fibroblast growth factor; FGFR1; The fibroblast growth factor receptor1; FGFR2; The fibroblast growth factor receptor2;
FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study
Keywords: Endometrial cancer; FGFR2; Mutation; Outcome; Prognosis;
Sry and SoxE genes: How they participate in mammalian sex determination and gonadal development?
Keywords: SRY; sex determining region Y; SOX9; SRY box 9; RSPO1; R-spondin 1; Wnt4; wingless-type MMTV integration site family member 4; Foxl2; forkhead box L2; Sox8; SRY (sex determining region Y)-box 8; DSD(s); Disorder(s) of sex development; HMG; high mobility g
Investigation of G-quadruplex formation in the FGFR2 promoter region and its transcriptional regulation by liensinine
Keywords: FGFR2; G-quadruplex; Liensinine; Breast cancer; Gene inhibitor;
Functional integration of complex miRNA networks in central and peripheral lesion and axonal regeneration
Keywords: AAV(s); adeno-associated virus(es); ADAM; a disintegrin and metalloprotease; AGO(2); argonaut (2); AKT; protein kinase B; APC; adenomatous polyposis coli; ASO(s); antisense oligonucleotide(s); ATF3; activating transcription factor 3; BBB; blood brain barr
Maternal exposure to di-n-butyl phthalate (DBP) induces combined anorectal and urogenital malformations in male rat offspring
Keywords: DBP; di-n-butyl phthalate; EEDs; environmental endocrine disrupting compounds; ARMs; anorectal malformations; ARMs & hypospadias; anorectal malformations in combination with hypospadias; PND; postnatal day; Shh; sonic hedgehog; Bmp4; bone morphogenetic pr
Altered FGF signalling in congenital craniofacial and skeletal disorders
Keywords: FGF signalling; FGFR1; FGFR2; FGFR3; Bone development; Craniosynostosis; Skeletal dysplasia;
SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development
Keywords: AGRF; Australian genomic research facility; Amh; anti Müllerian hormone; BAC; bacterial artificial chromosome; CCL9; chemokine (C-C motif) ligand 9; CSLM; confocal laser scanning microscopy; CYP17A1; cytochrome p450 family 17, subfamily A, protein 1; Cyp
Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi
Keywords: EN; epidermal nevi; FGFR2; fibroblast growth factor receptor 2; KEN; keratinocytic epidermal nevi; WES; whole exome sequencing;
FGFR2c-mediated ERK-MAPK activity regulates coronal suture development
Keywords: FGF; FGFR2; Crouzon syndrome; Coronal suture; Craniosynostosis; ERK-MAPK;
Fronto-facial advancement and bipartition in Crouzon-Pfeiffer and Apert syndromes: Impact of fronto-facial surgery upon orbital and airway parameters in FGFR2 syndromes
Keywords: Monobloc-distraction; Orbit; 3D-cephalometry; Crouzon-Pfeiffer syndrome; Apert syndrome; FGFR2;
FGFR2 mutation in a patient without typical features of Pfeiffer syndrome – The emerging role of combined NGS and phenotype based strategies
Keywords: Pfeiffer syndrome; FGFR2; FGFR2 Ala172Asn mutation
Reduced Fgf10/Fgfr2 and androgen receptor (AR) in anorectal malformations male rats induced by di-n-butyl phthalate (DBP): A study on the local and systemic toxicology of DBP
Keywords: AGD; anogenital distance; AR; androgen receptor; ARMs; anorectal malformations; BW; body weight; DBP; di-n-butyl phthalate; EEDs; environmental endocrine-disrupting compounds; Fgf10; fibroblast growth factor 10; Fgfr2; fibroblast growth factor receptor 2;
Describing Crouzon and Pfeiffer syndrome based on principal component analysis
Keywords: Crouzon syndrome; Pfeiffer syndrome; Principal component analysis; Craniosynostosis; FGFR2; Three-dimensional imaging
Fgfr2 is required for the expansion of the early adrenocortical primordium
Keywords: Adrenocortical primordium; Proliferation; Coelomic epithelium; Conditional knockout; Tbx18; Fgfr2
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium
Keywords: CAVD; calcific aortic valve disease; ALP; alkaline phosphatase; IBSP; bone sialoprotein; SPARC; osteonectin; TGFβ; transforming growth factor beta; WNT; wingless-type MMTV integration site family; CSL; suppressor of hairless; MAML; mastermind-like protei
MicroRNAs in skin tissue engineering
Keywords: APC; antigen producing cell; Ago; argonaute protein; αSMA; alpha smooth muscle actin; BSE; bioengineered skin equivalent; CEA; cultured epithelial autograft; cKO; conditional knockout; CREB1; p-cAMP response element-binding protein 1; DMD; Duchenne muscu
Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues
Keywords: as; alisphenoid; bo; basioccipital; bs; basisphenoid; FGFR2; fibroblast growth factor receptor 2; Fgfr2+/S252W; ubiquitous Fgfr2 S252W mutants; fr; frontal; μCT; high resolution computed tomography; ipa; interparietal; la; lacrimal; lo; lateral occipital
Mutually exclusive FGFR2, HER2, and KRAS gene amplifications in gastric cancer revealed by multicolour FISH
Keywords: Multicolour FISH; Gastric cancer; Gene amplification; KRAS; FGFR2; HER2
Developmental differences in the expression of FGF receptors between human and mouse embryos
Keywords: Blastocyst; Trophoblast; Human; Mouse; FGF receptors; FGFR2; CDX2;
Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration
Keywords: FGFR2; FGF2; Ribosomal S6 kinase; RSK2; Breast cancer; Migration;
Original ArticleUpregulation of ANGPTL4 Messenger RNA and Protein in Severely Calcified Carotid Plaques
Keywords: Carotid plaque; calcification; microarray analysis; ANGPTL4; FGFR2; angiogenesis;
Regulation of cardiac and renal ischemia-reperfusion injury by microRNAs
Keywords: MicroRNAs; Ischemia-reperfusion injury; Kidney; Heart; Free radicals; CaMKII; calmodulin kinase II; DRP1; dynamin-related protein-1; EPC; endothelial progenitor cell; FGFR2; fibroblast growth factor receptor 2; Hsp20; heat shock protein 20; HIF-1α; hyp
Original ResearchFull Report: Basic and Translational-LiverRelationship Between Methylome and Transcriptome in Patients With Nonalcoholic Fatty Liver Disease
Keywords: NAFLD; DNA Methylation; Gene Expression; Microarrays; AHCY; adenosyl homocysteine; ALDH1L1; aldehyde dehydrogenase 1 family, member L1; BMI; body mass index; CGI; CpG islands; CASP1; caspase 1; DM; differentially methylated; FGFR2; fibroblast growth facto
Rapid detection of de novo P253R mutation in FGFR2 using uncultured amniocytes in a pregnancy affected by polyhydramnios, Blake's pouch cyst, and Apert syndrome
Keywords: Apert syndrome; Blake's pouch cyst; FGFR2; P253R; prenatal diagnosis
MiR-19b-1 inhibits angiogenesis by blocking cell cycle progression of endothelial cells
Keywords: cDNA; complementary DNA; HUVEC; human umbilical vein endothelial cell; FGFR2; fibroblast growth factor receptor 2; Flk-1; fetal liver kinase-1; GAPDH; glyceraldehyde phosphate dehydrogenase; ITGB8; integrin β8; miR-19b-1; microRNA-19b-1; miRNA; microRNA;
CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling
Keywords: CCN2; FGFR2; FGF2; Osteoblast; Differentiation;
SÃndrome de Crouzon: a propósito de 2 casos. Entidades craneoestenóticas alélicas de los genes FGFR
Keywords: Acantosis nigricans; Antley-Bixler; Apert; Beare-Stevenson; Craneosinostosis; Crouzon; FGFR1; FGFR2; FGFR3; Jackson-Weiss; Muenke; Enanismo en sacabocados; Pfeiffer; Saethre-Chotzen; Acanthosis nigricans; Antley-Bixler; Apert; Beare-Stevenson; Craniosynos
Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche
Keywords: Small intestine; FGF10; FGFR2; Differentiation; Progenitor; Mesenchymal–epithelial signaling
FGFR2 mutations are rare across histologic subtypes of ovarian cancer
Keywords: Ovarian carcinoma; FGFR2; Mutation
Genetic variation in human P450 oxidoreductase
Keywords: Adrenal hyperplasia; Steroidogenesis; Antley-Bixler syndrome; FGFR2; Steroid hormone; Pharmacogenetics; Drug metabolism; Polymorphism;
Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology
Keywords: Fgfr2; Craniosynostosis; Apert syndrome; Osteoblast; Coronal suture; Calvaria; Mouse; Intramembranous ossification;
The study of abnormal bone development in the Apert syndrome Fgfr2+/S252W mouse using a 3D hydrogel culture model
Keywords: Tissue engineering; Apert syndrome; FGFR2; Osteoblast; Hydrogel;
Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure
Keywords: Twist1; FGFR2; FGF; BMP; bHLH; Craniosynostosis; Calvaria; Sutures; Craniofacial; Osteoblast differentiation
Loss of Fgfr2 leads to partial XY sex reversal
Keywords: Sex determination; XY sex reversal; SOX9; FGFR2; FGF9; PGDS; FGF signalling; Ovotestis; Disorders of sexual development; TestisAMH, anti-Müllerian hormone; B6, C57BL6; Bmp2, bone morphogenetic protein 2; Ck19, cytokeratin 19; Cyp26b1, cytochrome P450 26b1
Roles of FGFR3 during morphogenesis of Meckel's cartilage and mandibular bones
Keywords: GFR3; FGFR2; Chick mandible; Meckel's cartilage; Mandibular bones; RCAS;