Keywords: BDNF; brain-derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CNO; clozapine-n-oxide; CNS; central nervous system; DG; dentate gyrus; DH; dorsal hippocampus; DMSO; dimethyl sulfoxide; FGF2; Fibroblast growth factor-2; FGFR; Fibroblast Gro
مقالات ISI (ترجمه نشده)
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Keywords: Alagille syndrome; JAG1; NOTCH2; Syndromic craniosynostosis; Unilateral plagiocephaly; CT; Computed tomography; FGFR; Fibroblast growth factor receptor;
Keywords: Aβ; amyloid-β; BBB; blood-brain-barrier; CaMKII; calcium calmodulin kinase II; CFC; contextual fear conditioning test; DAG; diacylglycerol; F3; fibronectin type III module; FGFR; fibroblast growth factor receptor; GABAAR; γ-aminobutyric acid A recept
Keywords: Esophageal Cancer; Genomics; Epigenomics; ADAR; adenosine deaminases acting on RNA; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; BCH; basal cell hyperplasia; CIS; carcinoma in situ; CNA; copy number alteration; ESCC; esophagea
Keywords: craniosynostosis; foramen lacerum; carotid artery; FGFR; TWIST1; skull base; coronal suture; Crouzon syndrome;
Keywords: BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; FGFR; fibroblast growth factor receptor; GLT-1; glutamate transporter 1; ICH; intracerebral hemorrhage; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NDS; neurological
Keywords: Polymeric nanomedicines; Peptide; Cancer therapy; Therapeutic delivery; AF; aminoflavone; ANG; angiopep-2; BBB; blood brain barrier; BCECs; brain capillary endothelial cells; BP; bortezomib-pinanediol; bPEISS; bioreducible branched polyethylenimine; BPLP;
Keywords: ALK1; activin receptor-like kinase1; ANG/Ang; angiopoietin; Bcl-xL; b-cell lymphoma-extra large; BM; bone marrow; BMDCs; bone marrow derived cells; BMP; bone morphogenetic protein; Bv8; bombina variagata peptide 8; CAFs; cancer/carcinoma associated fibrob
Keywords: EGFR; Epidermal growth factor receptor; TP53; Tumor protein p53; KRAS; Kirsten rat carcoma viral oncogene; ALK; Anaplastic lymphoma kinase; RTK; Protein receptor tyrosine kinase; TKI; Tyrosine kinase inhibitor; PI3K; Phosphatidylinositol 3-kinase; NSCLC;
Keywords: Baicalin; Baicalein; Flavonoids; Chemoprevention; Inflammatory diseases; 6-OHDA; 6-hydroxydopamine; 12-LOX; 12-lipoxygenase; AIDS; acquired immunodeficiency disorder syndrome; AhR; aryl hydrocarbon receptor; AIH; autoimmune hepatitis; AICAR; 5-aminoimidaz
Keywords: Liver Cancer; Next-Generation Sequencing; Patient-Derived Cell Lines; Targeted Therapy; AFP; α-fetoprotein; FGFR; fibroblast growth factor receptor; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; IC50; 50% inhibitory concentration; ITH; intratumo
Keywords: Ac; acetyl group; AUC; area under the curve; BBB; Blood-brain barrier; BCRP; breast cancer resistance protein; CDK; cyclin-dependent kinase; CLIA; Clinical Laboratory Improvement Amendments; CNS; Central nervous system; CNS-TAP; CNS Targeted Agent Predict
Keywords: AC; articular cartilage; Akt; RAC-alpha serine/threonine-protein kinase; AGE; advanced glycation end products; ALK; activin receptor-like kinase; APO-A; apolipoprotein A; BMP; bone morphogenetic protein; CRP; C-reactive protein; ECM; extracellular matrix;
Keywords: CPPs; cell-penetrating peptides; CS; chitosan; DBP; DNA binding peptide; DMMAn; dimethylmaleic anhydride; EAP; eight-armed polyethylene glycol; EAPP; EAP-PEI copolymer; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; Eph; hepatocellu
Keywords: AngII; angiotensin II; CKD; chronic kidney disease; EGF; epidermal growth factor; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; FRS2α; FGF receptor substrate 2α; HPG; heparan sulfate proteoglycans; IGF-1; insulin-like growth fa
Keywords: FGFR; Phylogeny; Gene duplications; Whole genome duplications; Vertebrates; Human chromosomes; Paralogon;
Keywords: ACTA2; α-actin 2; α-SMA; α-smooth muscle actin; bFGF; basic fibroblast growth factor; Col1a1; collagen type 1; CSPG4; chondroitin sulfate proteoglycan 4; CTGF; connective tissue growth factor; FAPs; fibro/adipogenic progenitors; FGFR; fibroblast growth
Keywords: FGFR; FGF ligand; EGFR; Receptor tyrosine kinase; Targeted therapy;
Keywords: AEC; apical epithelial cap; AGP; anterior gradient protein; BDNF; brain-derived neurotrophic factor; Cnox-2; paraHox gsx homologue gene; DUOX; dual oxidase; EGR; early growth response; ERK; extracellular signal-regulated kinase; FGF; fibroblast growth fac
Keywords: AAV; adeno-associated virus; BDNF; brain-derived neurotrophic factor; CNP; 2â²,3â²-cyclic nucleotide 3â²-phosphodiesterase; CNS; central nervous system; CNTF; ciliary neurotrophic factor; CNTFRα; ciliary neurotrophic factor receptor alpha; Cop-1; copa
Keywords: C3G; cyanidin-3-glucoside; COX; cyclooxygenase; DADS; diallyl disulfide; EC; endothelial cell; EGCG; epicatechin-3-gallate and epigallocatechin-3-gallate; EGFR; epidermal growth factor receptor; eNOS; endothelial nitric oxide synthase; FGFR; fibroblast gr
Keywords: ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Keywords: Targeted receptor TKIs; Acquired resistance to receptor TKIs; Overcoming drug resistance; Driver oncogenes; Gate keeper receptor mutations; Bypass signaling molecules; ABC; ATP-binding cassette; AKT/PKB; Protein kinase B; ALK; Anaplastic lymphoma kinase;
Keywords: Afatinib (PubMed CID: 10184653); Crizotinib (PubMed CID: 11626560); Erlotinib (PubMed CID: 176870); Gefitinib (PubMed CID: 123631); Imatinib (PubMed CID: 5291); Nilotinib (PubMed CID: 644241); Sorafinib (PubMed CID: 216239); Sunitinib (PubMed CID: 5329102
Keywords: FGFR; growth plate; cholesterol; achondroplasia; iPS;
Keywords: GAG; glycosaminoglycan; GlcA; d-glucuronic acid; GlcA2SO3; d-glucuronic acid 2-sulfate; GlcN; d-glucosamine; GlcNSO36SO3; d-glucosamine N,6-sulfated; IdoA; l-iduronic acid; IdoA2SO3; l-iduronic acid 2-sulfate; TSD; trisulfated disaccharide; AT; antithromb
Keywords: acute uremia; calcium; FGFR; FGF23; parathyroid hormone; phosphate;
Keywords: 5-HT2a; 5-hydroxytryptamine receptor, type 2a; ABMD; adiabatic bias molecular dynamics; AMBER; assisted model building with energy refinement program; BPTI; bovine pancreatic trypsin inhibitor; COX; cyclooxygenase; CPU; central processing unit; CV; collec
Keywords: Cancer; FGFR; Clinical inhibitors; Resistance mutations
Keywords: AEX; anion exchange chromatography; CID; collision induced dissociation; DHB; 2,5-dihydroxybenzoic acid; ECD; electron capture dissociation; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; EGFRvIII; epidermal growth factor receptor v
Keywords: DNA damage response; Cell cycle regulation; PI3K/mTOR; NOTCH; c-MET; FGFR; Axl; Angiogenesis;
Keywords: AKAP; A-Kinase Anchoring Protein; ALL; acute lymphoblastic leukemia; A.S.; activation segment; CDK; cyclin-dependent kinase; CML; chronic myelogenous leukemia; C-spine; catalytic spine; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth facto
Keywords: ALK; anaplastic lymphoma kinase; EGFR; epidermal growth factor receptor; FGFR; fibroblast growth factor receptor; FISH; fluorescence in situ hybridization; MET; mesenchymal epithelial transition; NGS; next-generation sequencing; SQCC; squamous cell carcin
Keywords: ECM; Extracellular matrix; FGF; Fibroblast growth factor; FGFR; Fibroblast growth factor receptor; GAG; Glycosaminoglycan; GO; Gene ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; HP; Heparin; HS; Heparan sulfate; LMW; Low molecular weight; MMP;
Keywords: aFGF; acidic fibroblast growth factor; Ang-2; angiopoietin-2; bFGF; basic fibroblast growth factor; Conc; concentration; FGFR; fibroblast growth factor receptor; G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulati
Keywords: Chemical proteomics; Kinobeads; FGFR; LC-MS/MS;
Keywords: No; nitric oxide; eNOS; endothelial nitric oxide synthase; VEGF; vascular endothelial growth factor; LSECs; liver sinusoidal endothelial cells; HSCs; hepatic stellate cells; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; PIGF; pla
Keywords: Bn; bombesin; BnR; bombesin receptor; BR; biotin receptor; c(RGD-K); cyclic {Arginine-Glycine-Aspartic acid (RGD)} containing peptide; CA; cholic acid; DOX; doxorubicin; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ETRB; endotheli
Keywords: VEGF; vascular endothelial growth factor; CRC; colorectal cancer; VEGFR; VEGF receptors; PLGF; placental growth factor; HGF; hepatocyte growth factor; Il; Interleukin; Del-1; developmentally-regulated endothelial cell locus 1 protein; FGF; fibroblast grow
Keywords: Hpf; hours postfertilization; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; mRNA expression; Development; Embryonic; Danio rerio;
Keywords: FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; DESC; dental epithelial stem cell; CL; cervical loop; SC; stem cell; OEE; outer enamel epithelium; IEE; inner enamel epithelium; SR; stellate reticulum; SI; stratum intermedium; Alp;
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families
Keywords: Hepatocellular carcinoma; Sorafenib; Regorafenib; Levnatinib; Invasion; Metastasis; Hepatocellular carcinoma; HCC; Matrix metalloproteinases; MMPs; Tissue inhibitors of MMPs; TIMPs; Extracellular matrix; ECM; Receptor tyrosine kinases; RTKs; Vascular endo
Analysis of the FGFR spatiotemporal expression pattern within the chicken scleral ossicle system
Keywords: FGF; FGFR; Conjunctival papillae; Scleral ossicles; Intramembranous ossification; Gallus gallus; Eye; Fibroblast growth factor;
The localisation of the heparin binding sites of human and murine interleukin-12 within the carboxyterminal domain of the P40 subunit
Keywords: Interleukin-12; Interleukin-23; Heparin; Heparan sulfate; P40 subunit; Docking calculations; BMP; bone morphogenetic protein; CS; chondroitin sulphate; FGF; fibroblast growth factor; FGFR; fibroblast growth factor receptor; GAG; glycosaminoglycan; GDNF; g
KRAS-Mutant non-small cell lung cancer: From biology to therapy
Keywords: BATTLE; Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination; BET; bromodomains and extra-terminal domain; CDK; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CI; confidence interval; CUSTOM; Molecular Profiling and Targete
Dually modified transmembrane proteoglycans in development and disease
Keywords: ActR; activin type receptor; ALK; activin receptor like kinase; AV; atrioventricular cushion; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; C1; conserved domain 1; C2; conserved domain 2; Cdc42; control protein 42 homolog; CS
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors
Keywords: FGFR; VEGFR; Synergistic effect; Tumor growth inhibition; Lucitanib;
Highly efficient production of functional recombinant human fibroblast growth factor 22 in E. coli and its protective effects on H2O2-lesioned L02â¯cells
Keywords: rhFGF22; Inclusion body; Two-step denaturing method; Protective effects; Mitochondrial apoptotic pathways; FGF; human fibroblast growth factor; rhFGF22; recombinant human FGF22; FGFR; FGF receptors; PTZ; pentylenetetrazol; ROS; reactive oxygen species; Gd
Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib
Keywords: Autophagy; Combination therapy; Erlotinib; Vps34; High-content screening; AKT; Protein kinase B; ATG7; Autophagy-related protein 7; BafA1; Bafilomycin A1; Chk1; Checkpoint kinase 1; CQ; Chloroquine; FGFR; Fibroblast growth factor receptor; GFP; Green fluo
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli