دانلود مقالات ISI درباره Fk506 + ترجمه فارسی

Immunophilin deficiency augments Ca2+-dependent glutamate release from mouse cortical astrocytes

Keywords: Calcineurin; Cyclophilin D; Cyclosporin A; Exocytosis; FK506; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration

Keywords: BDNF; brain-derived neurotrophic factor; BrdU; bromodeoxyuridine; CNS; central nervous system; CNTF; ciliary neurotrophic factor; CsA; cyclosporin A; ECM; extracellular matrix; ePTFE; expanded polytetrafluoroethylene; ESC; embryonic stem cell; FGFs; fibro

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2011 سفارش ترجمه

Selective elution of target protein from affinity resins by a simple reductant with a thiol group

Keywords: Affinity resins; Target identification; Carbonic anhydrase II; FKBP12; Benzenesulfonamide; FK506; 2-Mercaptethanol (2ME); AquaFirmus

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Neuroprotective effects of FK506 against excitotoxicity in organotypic hippocampal slice culture

Keywords: FK506; Kainic acid; Organotypic hippocampal slice culture; Neuroprotection

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

The calcineurin inhibitor, FK506, does not alter glutamate transport in the ischaemic mouse retina

Keywords: Ischemia; neuroprotection; retina; glaucoma; calcineurin; glutamate transporter; EAAT; FK506

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

The Positive Effect of Immunosuppression on Adaptation of Venous Allografts to Arterialisation in Rats

Keywords: FK506; Rats; Transplantation; Venous allografts

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins

Keywords: Affinity resins; Poly(methacrylate); Benzensulfonamide; Carbonic anhydrase 2; FK506; Calcineurin

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Intermediate- and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition

Keywords: Alzheimer's disease; Novel object recognition; FK506; Short-term memory; Intermediate-term memory; Long-term memory; Retention interval

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Direct vasodilative effect of FK506 on porcine mesenteric artery in small bowel transplantation

Keywords: FK506; Small bowel transplantation; Smooth muscle; Vascular tone; Ischemia-Reperfusion injury;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Immunosuppressant FK506 decreases the intracellular magnesium in the human osteoblast cell by inhibiting the ERK1/2 pathway

Keywords: FK506; Human osteoblast(HOB); Magnesium; ERK 1/2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Calcineurin inhibition eliminates the normal inverted U curve, enhances acquisition and prolongs memory in a mammalian 3′-5′-cyclic AMP–dependent learning paradigm

Keywords: protein phosphatase 2B; FK506; odor preference learning; rat pups; isoproterenolANOVA, analysis of variance; cAMP, 3′-5′-cyclic AMP; CaN, calcineurin, protein phosphatase 2B; CREB, 3′-5′-cyclic AMP response element binding protein; CS, conditioning stimul

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Promotion of Nerve Regeneration in Peripheral Nerve by Short-Course FK506 after End-to-Side Neurorrhaphy

Keywords: peripheral nerve; end-to-side neurorrhaphy; regeneration; short-course; FK506

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

FK506 and Rapamycin Neuroprotect Erection and Involve Different Immunophilins in a Rat Model of Cavernous Nerve Injury

Keywords: FK506; Rapamycin; Cavernous Nerve; Immunophilin; FKBP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Effect of FK506 and cyclosporine A on the expression of BDNF, tyrosine kinase B and p75 neurotrophin receptors in astrocytes exposed to simulated ischemia in vitro

Keywords: FK506; Cyclosporine A; Astrocytes; Ischemia; BDNF; p-CREB; TrkB; p75NTR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Tacrolimus causes a blockage of protein secretion which reinforces its immunosuppressive activity and also explains some of its toxic side-effects

Keywords: Tacrolimus; FK506; Brefeldin A; Secretory pathway; Immunosuppressive side-effects; Jurkat cells; MIN6 cells

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Spliceosomal immunophilins

Keywords: Cyclophilin; FKBP; Spliceosome; Cyclosporin; FK506; Small nuclear RNAs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Effect of tacrolimus on the cauda epididymis in rats: Analysis of epididymal biochemical markers or antioxidant defense enzymes

Keywords: Tacrolimus; FK506; Rat; Epididymis; Sperm count; l-Carnitine; Antioxidant defense enzyme;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Activation of the nuclear factor of activated T-cells (NFAT) mediates upregulation of CCR2 chemokine receptors in dorsal root ganglion (DRG) neurons: A possible mechanism for activity-dependent transcription in DRG neurons in association with neuropathic

Keywords: Chemokine receptors; Dorsal root ganglion; Neuropathic pain; NFAT; Calcineurin; FK506; Cyclosporin A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Increased Ca2+ sparks and sarcoplasmic reticulum Ca2+ stores potentially determine the spontaneous activity of pulmonary vein cardiomyocytes

Keywords: Atrial fibrillation; Calcium spark; Calcium transient; FK506; Magnesium; Pulmonary veins

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: Heat shock protein 70 levels are modulated in microglial cells

Keywords: FK506; spinal cord injury; organotypic culture; motoneuron; microglia; neuroprotectionEthD, ethidium homodimer-1; FKBP12, 12-kDa immunophilin FK506-binding protein; Hsp, heat shock protein; LPS, lipopolysaccharide; NO, nitric oxide; P, postnatal day; PBS,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

FK506 and Erectile Function Preservation in the Cavernous Nerve Injury Model: Optimal Dosing and Timing

Keywords: Immunophilin Ligand; FK506; Animal Model; Cavernous Nerve Injury; Erectile Function Preservation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

FK506-protective effects against trimethyltin neurotoxicity in rats: Hippocampal expression analyses reveal the involvement of periarterial osteopontin

Keywords: trimethyltin; FK506; hippocampal CA1 subregion; microarray; osteopontin; periarterial area; BBB; blood-brain barrier; COX-2; cyclooxygenase-2; CT; cycle threshold; GST; glutathione S-transferase; KA; kainic acid; MGP; Matrix Gla protein; OPN; osteoponti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Two independent forms of endocytosis maintain embryonic cell surface homeostasis during early development

Keywords: Sea urchin; FM1-43; Endocytosis; PAO; Agatoxin; Src kinase; FK506; Staurosporine; PMA;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

FK506 induces interleukin-6 secretion from UVB irradiated cultured human keratinocytes via p38 mitogen-activated protein kinase pathway: Implication on mechanisms of tacrolimus-induced skin irritation

Keywords: FK506; Keratinocyte; IL-6; p38 MAPK;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Is excitation–contraction coupling impaired in myasthenia gravis?

Keywords: Myasthenia gravis; Excitation–contraction coupling; FK506; Ryanodine receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

PET measurement of FK506 concentration in a monkey model of stroke

Keywords: FK506; Stroke; Neuroprotectant; Positron emission tomography; Brain concentration

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts

Keywords: Chronic rejection; Fibrosis; FK506; rapamycin; Vasculopathy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Expression, purification, and molecular characterization of Plasmodium falciparum FK506-binding protein 35 (PfFKBP35)

Keywords: FK506; FKBP; Calcineurin; Malaria; Plasmodium falciparum; NMR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

FK1706 Enhances the Recovery of Erectile Function Following Bilateral Cavernous Nerve Crush Injury in the Rat

Keywords: Neurogenic Impotence; FK1706; FK506; Immunophilin Ligand; Animal Model; Erectile Dysfunction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Induction of cerebellar long-term depression requires activation of calcineurin in Purkinje cells

Keywords: Long-term depression; Ca2+ signaling; Calcineurin; Cyclosporin A; FK506; Purkinje cell

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice

Keywords: Amyloid beta; Calcineurin; Tg2576 mice; Fear conditioning; Behavior; FK506; SY5Y cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Therapeutic time window of tacrolimus (FK506) in a nonhuman primate stroke model: Comparison with tissue plasminogen activator

Keywords: Focal cerebral ischemia; Nonhuman primate; Therapeutic time window; Tissue plasminogen activator; FK506;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

FK506 and Sildenafil Promote Erectile Function Recovery after Cavernous Nerve Injury Through Antioxidative Mechanisms

Keywords: Antiapoptotic; Antioxidant Enzyme; Cavernous Nerve; FK506; Oxidative Stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

The immunosuppressant FK506 promotes development of the chondrogenic phenotype in human synovial stromal cells via modulation of the Smad signaling pathway

Keywords: FK506; BMP; TGFβ; Synovium; Tissue engineering; Cartilage repair

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Tacrolimus (FK506) reduces hippocampal damage but fails to prevent learning and memory deficits after transient, global cerebral ischemia in rats

Keywords: Global cerebral ischemia; Neurodegeneration; FK506; Neuroprotection; Learning and memory; Aversive radial maze;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Long-term therapeutic efficacy and safety of low-dose tacrolimus (FK506) for myasthenia gravis

Keywords: Tacrolimus hydrate; FK506; Myasthenia gravis; Treatment; Adverse effects

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Development of chemically stable solid phases for the target isolation with reduced nonspecific binding proteins

Keywords: Nonspecific binding proteins; Affinity chromatography; Poly(methacrylate); FK506; FKBP12; FKBP52;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Beneficial effects of FK506 for experimental temporal lobe epilepsy

Keywords: FK506; Temporal lobe epilepsy; Behavioral change; Neuronal cell death; Kainic acid; Trimethyltin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

The intracellular domain of amyloid precursor protein interacts with FKBP12

Keywords: FKBPs; Alzheimer’s disease; AICD (APP intracellular domain); FK506

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

An easy preparation of ‘monolithic type’ hydrophilic solid phase: Capability for affinity resin to isolate target proteins

Keywords: Affinity resins; Poly(methacrylate); Monolith; FK506

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-α-stimulated human hepatic stellate cells

Keywords: FK506; Hepatic stellate cells; NF-κB; Matrix metalloproteinase; TNF-α

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Reduction of nonspecific binding proteins to self-assembled monolayer on gold surface

Keywords: Nonspecific binding proteins; Surface plasmon resonance; FK506; FKBP12

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

FK506, transforming growth factor-β1 and mesangial matrix synthesis: Parallels and differences compared with cyclosporine A

Keywords: FK506; Glomerulosclerosis; Kidney transplantation; Mesangial cells; Transforming growth factor-β

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Immunosuppressants inhibit hormone-stimulated Mg2+ uptake in mouse distal convoluted tubule cells

Keywords: FK506; Cyclosporin A; Immunosuppressant; Intracellular calcium; Magnesium; ERK; MDCT cells

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Efficacy of Transient Treatment with FK506 in the Early Phase on Cyclophosphamide-Induced Bone Marrow Chimerism and Transplant Tolerance across MHC Barriers1

Keywords: cyclophosphamide; FK506; bone marrow transplantation; chimerism; tolerance; transplantation; rats

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Glucocorticoid resistance in squirrel monkeys results from a combination of a transcriptionally incompetent glucocorticoid receptor and overexpression of the glucocorticoid receptor co-chaperone FKBP51

Keywords: COS-7; SQMK-FP; 293; Tetracycline; FK506; Immunophilin; Cells

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

A versatile method of identifying specific binding proteins on affinity resins

Keywords: Affinity resins; Competition method; Target identification; Nonspecific binding proteins; FKBP12; Carbonic anhydrase II; Dihydrofolate reductase; FK506; Benzenesulfonamide; Methotrexate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening

Keywords: Electrochemical detection; Homogeneous assay; Drug screening; Receptor binding assay; FK506; FKBP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury

Keywords: Traumatic brain injury; Axonal damage; Amyloid precursor protein (APP); Immunophilin ligands; FK506; Neurofilament compaction (NFC)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Structural Characterization of the RyR1–FKBP12 Interaction

Keywords: cryo-electron microscopy; FK506; FKBP12; ryanodine receptorCn, calcineurin; EM, electron microscopy; FKBP12, FK506-binding protein 12 kDa; FKBP12.6, FK506-binding protein 12.6 kDa; FRAP, FKBP12-rapamycin-associated protein; GFP, green fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه