دانلود مقالات ISI درباره Fkbp + ترجمه فارسی

فعال سازی پیشگیرانه منجر به تخریب پروتئین شرطی

Research paperInduced prodrug activation by conditional protein degradation

Keywords: yCD; yeast cytosine deaminase; 5-FC; 5-fluorocytosine; 5-FU; 5-fluorouracil; PCE; prodrug converting enzymeprodrug converting enzyme; DDEPT; degradation-directed enzyme prodrug therapy; DD; degradation domain; TShld; traceless shielding; FKBP; FK506 bindi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

تنظیم رونویسی ژن بر اساس بسته بندی و تحویل القا شده از طریق ویجت های خارج سلول

Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles

Keywords: Extracellular vesicles; Dimerization; TALE; Transcriptional regulation; BFP; blue fluorescent protein; CIB1; cryptochrome-interacting, basic-helix-loop-helix1; CRY2; cryptochrome 2; ctrl; control; eGFP; enhanced green fluorescent protein; ePDZb; engineere

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

مطالعات وابسته به اندازه کروماتوگرافی ماکرو مولکولی بر پایداری ترمودینامیکی، ساختار و فعالیت عملکرد پروتئین: در شرایط آزمایشگاهی و در روش های سیلیکا

Size-dependent studies of macromolecular crowding on the thermodynamic stability, structure and functional activity of proteins: in vitro and in silico approaches

Keywords: PEG; polyethylene glycol; FKBP; FK-506 binding protein; HSA; human serum albumin; GdmCl; guanidinium chloride; Tm; midpoint of denaturation; ΔHm; enthalpy change at Tm; Trp; tryptophan; bOBP; bovine odorant binding protein; BSA; bovine serum albumin; ANS

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2017 سفارش ترجمه

پپتیدیل پرولییل چندساله / ترانس ایزومراز

Multidomain Peptidyl Prolyl cis/trans Isomerases

Keywords: Peptidyl prolyl cis/trans isomerase; Multidomain; Cyclophilin; FKBP; Pin1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

مکانیسم ها و ارزیابی ریسک مقاومت استروئیدی در رد پیوند حاد کلیه

Mechanisms and risk assessment of steroid resistance in acute kidney transplant rejection

Keywords: AP-1; activator protein-1; AR; acute rejection; ATG; anti-thymocyte globulin; CAN; chronic allograft nephropathy; CBP; CREB-binding protein; CREB; cyclic AMP-responsive element-binding; DBD; DNA-binding domain; F2R; coagulation factor II receptor; FKBP; F

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

ایمونوفیلین های گیاهی: بررسی رابطه ساختار-عملکرد آنها

Plant immunophilins: a review of their structure-function relationship

Keywords: Immunophilin; FK506; FKBP; Cyclophilin; Cyclosporin; Redox;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors

Keywords: AP-1; activator protein 1; CNI; calcineurin inhibitor(s); ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ERK; extracellular signal regulated kinase; FKBP; FK506 binding protein; JNK; Jun N-terminal kinase; LAP; latency-associated pr

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Autophagy as a pharmacological target in hematopoiesis and hematological disorders

Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5′-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2018 سفارش ترجمه

AIPL1: A specialized chaperone for the phototransduction effector

Keywords: AIPL1; aryl hydrocarbon receptor-interacting protein-like 1; PDE6; photoreceptor phosphodiesterase-6; AIP; aryl hydrocarbon receptor-interacting protein; LCA; Leber congenital amaurosis; FKBP; FK506-binding proteins; TPR; tetratricopeptide repeat; PDE6D;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original articleRyanodine receptor modification and regulation by intracellular Ca2 + and Mg2 + in healthy and failing human hearts

Keywords: CaM; Calmodulin; CaMKII; Calmodulin kinase II; CF; Cystic fibrosis; CSQ2; Calsequestrin type 2; DADs; Delayed after-depolarizations; EDMD; Emery Dreifuss muscular dystrophy; FKBP; FK binding protein; ICM; Ischaemic cardiomyopathy; ko; Opening rate; PKA; P

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Total internal reflectance fluorescence imaging of genetically engineered ryanodine receptor-targeted Ca2+ probes in rat ventricular myocytes

Keywords: Cardiac Ca2+ signaling; Ryanodine receptor; FKBP; Genetically engineered Ca2+ probe; Ca2+ sparks; Dyadic Ca2+signals;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Mechanisms of mutant PDE6 proteins underlying retinal diseases

Keywords: PDE6; photoreceptor phosphodiesterase-6; AIPL1; aryl hydrocarbon receptor-interacting protein-like 1; LCA; Leber congenital amaurosis; FKBP; FK506-binding proteins; TPR; tetratricopeptide repeat; GAF; domains named for their presence in cGMP-regulated PDE

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

Rapamycin-induced oligomer formation system of FRB–FKBP fusion proteins

Keywords: FRB; FKBP; Rapamycin; Oligomer; Chemically-induced oligomerization; Protein engineering

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift

Keywords: AIP; autocamtide-2 related inhibitory peptide; Bmax; binding maximum; CaM; calmodulin; CaMKII; calcium/calmodulin-dependent protein kinase II; CaSpF; calcium spark frequency; CPVT; catecholaminergic polymorphic ventricular tachycardia; DAN; dantrolene; F;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

Keywords: DAG; diacylglycerol; PPIns; phosphoinositides; RTK; receptor tyrosine kinase; GPCR; G-protein coupled receptor; Ins(1,4,5)P3; inositol 1,4,5-trisphosphate; PM; plasma membrane; BRET; bioluminescence resonance energy transfer; PLC; phospholipase C; PtdIns(

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage

Keywords: APP; β-amyloid precursor protein; bioFET; biologically coupled field effect transistor; CASP; caspase; CCD; charge-coupled device; CHX; cycloheximide; DMEM; Dulbecco's Modified Eagle's Medium; EEA1; early endosome antigen 1; EGFP; enhanced green fluoresc

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2016 سفارش ترجمه

Artificial regulation of p53 function by modulating its assembly

Keywords: p53; Rapamycin; FRB; FKBP; Chemically induced oligomerization; Protein engineering;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of the mevalonate pathway ameliorates anoxia-induced down-regulation of FKBP12.6 and intracellular calcium handling dysfunction in H9c2 cells

Keywords: DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; FKBP; FK506-binding protein; FPP; farnesyl pyrophosphate; GAPDH; glyceraldehyde phosphate dehydrogenase; GGPP; geranylgeranyl pyrophosphate; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Insights into peptidyl-prolyl cis-trans isomerase structure and function in immunocytes

Keywords: PPIases; Immunophilins; CyPA; FKBP; Cyclosporine A; FK506;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibiting prolyl isomerase activity by hybrid organic–inorganic molecules containing rhodium(II) fragments

Keywords: FKBP; Prolyl isomerase; Rhodium; Enzyme inhibition; Metallodrug

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Expression, purification and characterization of soluble recombinant peptidyl-prolyl cis/trans isomerase from Vibrio anguillarum

Keywords: Vibrio anguillarum; Peptidyl-prolyl cis/trans isomerase; FKBP; MIP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Statistical allosteric coupling to the active site indole ring flip equilibria in the FK506-binding domain

Keywords: PDB; protein data bank; FKBP; FK506 binding protein; NOESY; nuclear Overhauser enhancement spectroscopy; FKBP12; NMR; Allostery; Molecular simulation; Statistical coupling; Concerted transition;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Diversified targets of FKBP25 and its complex with rapamycin

Keywords: FKBP; Rapamycin; FKBP25; PPIase; Immunophilin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir

Keywords: EC50; 50% effective inhibitory concentration; CsA/CsD; cyclosporine A/D; PPIase; peptidyl prolyl cis/trans isomerase; CypA/B; cyclophilin A/B; ALV; Alisporivir; FKBP; FK506-binding protein; HCoV-NL63; Cyclosporine/FK506-non-immunosuppressive derivatives;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

From endosomes to the trans-Golgi network

Keywords: AD; Alzheimer disease; AP1; adaptor protein 1; APP; amyloid precursor protein; BAR; Bin/Amphiphysin/Rvs; CD-M6PR; cation-dependent mannose-6-phosphate receptor; CI-M6PR; cation-independent mannose-6-phosphate receptor; COG; conserved oligomeric Golgi comp

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The Fusarium Graminearum virulence factor FGL targets an FKBP12 immunophilin of wheat

Keywords: BiFC; Biomolecular fluorescence complementation; DON; Deoxynivalenol; ERG; Elicitor-responsive gene; ETI; Effector-triggered immunity; ETS; Effector-triggered susceptibility; FHB; Fusarium head blight; FKBP; FK506-binding protein; FKBP12; 12-kDa FK506-bin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway

Keywords: ANOVA; analysis of variance; bFGF; basic fibroblast growth factor; CsA; cyclosporin A; DMSO; dimethylsulfoxide; EGF; epidermal growth factor; eNOS; endothelial nitrogen oxide synthase; ERK; extracellular-regulated kinase; FKBP; FK506-binding protein; GAPD

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dynamic control of the prolyl isomerase function of the dual-domain SlyD protein

Keywords: NMR; Fluorescence; PPIase; FKBP; Dynamics; Enzymology;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Elastin-based protein polymer nanoparticles carrying drug at both corona and core suppress tumor growth in vivo

Keywords: Rapa; rapamycin; ELPs; elastin-like polypeptides; FKBP; FK506 binding protein 12; mTOR; mammalian target of rapamycin; ITC; inverse transition cycling; CMT; critical micelle temperature; CMC; critical micelle concentration; DLS; dynamic light scattering;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Modulation of human embryonic stem cell-derived cardiomyocyte growth: A testbed for studying human cardiac hypertrophy?

Keywords: ANF; atrial natriuretic factor; bFGF; basic human fibroblast growth factor; CaMK II; Ca2+/calmodulin-dependent kinase II; EB; embryoid body; ERK; extracellular signal-regulated kinases; GSK3; glycogen synthase kinase 3; HDACII; histone deacetylase; FKBP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Limitations of FKBP12.6-directed treatment strategies for maladaptive cardiac remodeling and heart failure

Keywords: Transgenic mice; Maladaptive remodelling; Heart failure; FKBP; CaMK; Pressure overload; Ca sparks; Ca transients;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Management of cytoskeleton architecture by molecular chaperones and immunophilins

Keywords: IMM; immunophilin; FKBP; FK506-binding protein; TPR; tetratricopeptide repeat; PPIase; peptidylprolyl-(cis/trans)-isomerase activity; Hsp; heat-shock protein; sHsp; small Hsp, Hsc, constitutively expressed heat-shock cognate 70-kDa; CHIP; carboxy-terminus

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26

Keywords: crystal structure; FKBP; PPIase; prolyl isomerase; protein–protein interactionsPPIase, peptidyl-prolylcis/trans isomerase; FKBP, FK506-binding protein; FKBP26, 26-kDa Methanococcus jannaschii FKBP; TF, trigger factor; IF, Insert-in-Flap domain; CTD, C-ter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2011 سفارش ترجمه

A thylakoid-localised FK506-binding protein in wheat may be linked to chloroplast biogenesis

Keywords: FKBP; Immunophilin; Chloroplast biogenesis; Photosynthesis; Molecular chaperoneFKBP, FK506- and rapamycin-binding protein; CYP, cyclophilin; PPIase, peptidyl prolyl cis/trans isomerase; CBM, chloroplast biogenesis module; SV, splice variant

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

The primary identification of a calcineurin A subunit-like protein in plants

Keywords: Calcineurin; Plant calcineurin A subunit-like protein; Protein phosphatase activity; CaNAL; CN; calcineurin; CNA; calcineurin A subunit; CNB; calcineurin B subunit; CaNAL; calcineurin A subunit-like protein; CaNBL; calcineurin B subunit-like protein; CaM;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Role of Immunophilins in Recovery of Erectile Function after Cavernous Nerve Injury

Keywords: Erectile Dysfunction; FKBP; Nitric Oxide; Cavernous Nerve; Crush Injury;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

FK506 and Rapamycin Neuroprotect Erection and Involve Different Immunophilins in a Rat Model of Cavernous Nerve Injury

Keywords: FK506; Rapamycin; Cavernous Nerve; Immunophilin; FKBP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Spliceosomal immunophilins

Keywords: Cyclophilin; FKBP; Spliceosome; Cyclosporin; FK506; Small nuclear RNAs

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

A fast and simple method to prepare the FKBP-rapamycin binding domain of human target of rapamycin for NMR binding assays

Keywords: Target of rapamycin; TOR; FKBP; Refolding; Inclusion body; HPLC; NMR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Identification of all FK506-binding proteins from Neurospora crassa

Keywords: Immunophilins; PPIase; FKBP; Protein folding; Neurospora crassa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Personal recollections on the discovery of the ryanodine receptors of muscle

Keywords: RyR; ryanodine receptor; CRC; calcium release channel; SR; sarcoplasmic reticulum; LT; longitudinal tubules; TT; transverse tubules; TC; terminal cisternae; JFM; junctional face membrane; JTC; junctional terminal cisternae; FKBP; FK506 Binding Protein; FS

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2008 سفارش ترجمه

Expression, purification, and molecular characterization of Plasmodium falciparum FK506-binding protein 35 (PfFKBP35)

Keywords: FK506; FKBP; Calcineurin; Malaria; Plasmodium falciparum; NMR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Cloning, expression and characterisation of FKB-6, the sole large TPR-containing immunophilin from C. elegans

Keywords: Large immunophilin; TPR tetratricopeptidel; Caenorhabditis elegans; FKBP; Hsp90

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Enhancing resistance of transgenic carrot to fungal pathogens by the expression of Pseudomonas fluorescence microbial factor 3 (MF3) gene

Keywords: FKBP, FK506-binding proteins; ISR, induced systemic resistance; MF3, microbial factor 3; PGPR, plant-growth promoting rhizobacteria; RAUDPC, relative area under the disease progress curveAgrobacterium tumefaciens; Binding proteins; Daucus carota; FKBP; Ge

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Profound redox sensitivity of peptidyl-prolyl isomerase activity in Arabidopsis thylakoid lumen

Keywords: FKBP, FK506 binding protein; PPIase, peptidyl-prolyl cis/trans isomeraseImmunophilin; FKBP; Cyclophilin; Peptidyl-prolyl isomerase; Thylakoid lumen; Arabidopsis thaliana

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

The FK506-binding protein, Fpr4, is an acidic histone chaperone

Keywords: FKBP, FK506-binding protein; PPIase, peptidylprolyl isomeraseHistone chaperone; Nucleosome assembly; FKBP

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Glucose oxidase assisted homogeneous electrochemical receptor binding assay for drug screening

Keywords: Electrochemical detection; Homogeneous assay; Drug screening; Receptor binding assay; FK506; FKBP

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Peptidyl-prolyl cis–trans isomerases (immunophilins) and their roles in parasite biochemistry, host–parasite interaction and antiparasitic drug action

Keywords: Protein folding; Cyclophilin; FKBP; Cyclosporin; FK506; Rapamycin

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

FKBP52

Keywords: Immunophilin; Tetratricopeptide repeat protein; FKBP; FK506; Steroid receptor; Chaperone; Hsp90;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه