Keywords: Adipose tissue; Cancer associated adipocytes; FABP4; FABP5; Lipid metabolism; ADF; adipocyte-derived fibroblasts; BAT; brown adipose tissue; BMAT; bone marrow adipose tissue; BMI; body mass index; CAA; cancer-associated adipocytes; CAF; cancer-associated
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Keywords: AP-1; activator protein-1; APP; amyloid precursor protein; AICD; APP intracellular domain; DAMPs; damage associated molecular patterns; FOXO3; forkhead box O3; HES; hairy-enhancer of split; HPCs; hematopoietic progenitor cells; HDAC; histone deacetylase;
Keywords: ACC; Acetyl-CoA carboxylase; ACSL; Long-chain acyl-CoA synthetase; AMPK; AMP-activated protein kinase; Apo; Apolipoprotein; ATGL; Adipose triglyceride lipase; CD36; Cluster of differentiation 36; CGI-58; Comparative gene identification-58; CIDE; Cell deat
Keywords: 27-HC; 27-Hydroxycholesterol; 3PO; 3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; ABCG1; ATP-binding cassette subfamily G1; ACBA1; ATP-binding cassette subfamily A1; ACC1; Acetyl-Co-A carboxylase-1; AKAP4; A-kinase anchoring protein 4; ALDO; Aldolase; AM
Keywords: AAV; adeno-associated virus; E2F; E2 transcription factor; FOXO3; Forkhead box protein O3; Nanog; Nanog homeobox transcription factor; NF-κB; nuclear factor-κB; Oct; octamer-binding protein; ODN; oligodeoxynucleotide; Sox; Sox transcription factor (refe
Keywords: CAF; cancer associated fibroblast; GRP78; glucose-regulated protein 78; DC; dendritic cell; NK; natural killer cell; MDSC; myeloid-derived suppressor cell; TIL; tumor-infiltration lymphocyte; TAM; tumor-associated macrophage; NSCLC; non-small cell lung ca
Keywords: AFLD; alcoholic fatty liver disease; AMPK; AMP-activated protein kinase; BSE; barley sprout extract; GC-MS; gas chromatography mass spectrometry; H&E; hematoxylin and eosin; PPAR; peroxisome proliferator-activated receptor; FOXO3; forkhead box O3; HFD;
Keywords: Aza; 5-aza 2 deoxycytidine; TSA; trichostatin A; MeCP2; methyl CpG binding protein 2; SLE; systemic lupus erythematosus; RA; rheumatoid arthritis; DNMTs; DNA methyltransferases; HDACs; histone deacetylases; HAT; histones acetyl transferases; HMT; histone
Keywords: Intestinal ischemia–reperfusion; SIRT1; Icariin; FOXO3; Oxidative stress; Apoptosis
Keywords: 2-Deoxyglucose; follicle activation; Foxo3; nutrient deprivation; ovarian reserve;
Keywords: AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: 31P-NMR; 31P nuclear magnetic resonance; AIF; apoptosis-inducing factor; AngII; angiotensin II; Atg protein; autophagy-related protein; Bcl-2; B-cell leukemia-2; COPD; chronic obstructive pulmonary disease; COX; cytochrome c oxidase; CSA; cross-sectional
The mechanisms involved in miR-9 regulated apoptosis in cervical cancer by targeting FOXO3
Keywords: miR-9; FOXO3; Cervical cancer; Apoptosis; Akt;
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
MicroRNA-30c-5p inhibits NLRP3 inflammasome-mediated endothelial cell pyroptosis through FOXO3 down-regulation in atherosclerosis
Keywords: Atherosclerosis; miR-30c-5p; NLRP3; Pyroptosis; FOXO3;
Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment
Keywords: Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;
Scutellaria: Debates on the anticancer property
Keywords: Bcl-2; B-cell lymphoma 2; 5-FU; 5-Fluorouracil; TGF-β1; transforming growth factor beta 1; PTEN; phosphatase and tensin homolog; HIF-1α; hypoxia-inducible factor 1-alpha; MAPK; mitogen-activated protein kinase; CRC; cyclic redundancy check; SHH; sonic h
MicroRNA-223-3p regulates cell chemo-sensitivity by targeting FOXO3 in prostatic cancer
Keywords: PCa; Prostate cancer; miRNAs; MicroRNAs; FOXO; forkhead box; qRT-PCR; Quantitative real-time polymerase chain reaction; SD; standard deviation; IC50; the half maximal inhibitory concentration; MiR-223-3p; Chemo-sensitivity; FOXO3; Prostatic cancer;
miR-487a-3p upregulated in type 1 diabetes targets CTLA4 and FOXO3
Keywords: T1D; Microarray; Expression; miR-487a-3p; CTLA4; FOXO3;
Up-regulation of miR-122 protects against neuronal cell death in ischemic stroke through the heat shock protein 70-dependent NF-κB pathway by targeting FOXO3
Keywords: Ischemic stroke; miR-122; FOXO3; Heat shock protein 70 (HSP-70); NF-κB pathway;
JNK1 as a signaling node in VDR-BRAF induction of cell death in AML
Keywords: AP-1; Activator protein 1, c-Jun and dimerization partners; AKT; Serine/threonine protein kinase B (PKB); AML; Acute myeloid leukemia; AraC; Cytarabine/Arabinocytosine; ASK1; Apoptosis signal regulating kinase 1; BCL2; B-cell lymphoma 2; BIM; Bcl-2-like p
Unravelling the role of fatty acid metabolism in cancer through the FOXO3-FOXM1 axis
Keywords: Fatty acids; Cancer; Lipid metabolism; FOXO3; FOXM1; AKT/PI3K pathway; AKT; protein kinase B; AMPK; adenosine monophosphate-activated-activated protein kinase; APN; adiponectin; CoA; coenzyme A; CPT1; carnitine palmitoyltransferase 1; DHA; docosahexaenoic
Folliculogenic factors in photoregressed ovaries: Differences in mRNA expression in early compared to late follicle development
Keywords: follicle stimulating hormone; FSH; follicle stimulating hormone receptor; FSHR; insulin-like growth factor 1; IGF1; cyclooxygenase; COX2; spermatogenesis and oogenesis specific basic helix-loop-helix 1; SOHLH1; newborn ovary homeobox; NOBOX; factor in the
MiR-155-5p promotes fibroblast cell proliferation and inhibits FOXO signaling pathway in vulvar lichen sclerosis by targeting FOXO3 and CDKN1B
Keywords: VLS; vulvar lichen sclerosis; miRNA; microRNA; miR-155-5p; microRNA 155-5p; 3'UTR; 3' untranslated region; FOXO3; forkhead O3; CDKN1B; cyclin-dependent kinase inhibitor 1B; CTS; corticosteroids; FOXO; forkhead O; miR-155-5p; Cell proliferation; Vulvar lic
MicroRNA-182 inhibits HCMV replication through activation of type I IFN response by targeting FOXO3 in neural cells
Keywords: HCMV; miR-182; FOXO3; IRF7; Type I IFN; Neural cells;
Serum miRNAs miR-140-3p and miR-23b-3p as potential biomarkers for osteoporosis and osteoporotic fracture in postmenopausal Mexican-Mestizo women
Keywords: BMD; Bone mineral density; OF; osteoporotic fracture; DXA; Dual-energy X-ray Absorptiometry; miRNA; microRNA; VC; Variation Coefficient; TLDA; TaqMan Low Density Array; SE; Standard error; AUC; Area Under the Curve; BMI; Body Mass Index; ROC; Receiver Ope
Mitochondria as pharmacological targets in Down syndrome
Keywords: AD; Alzheimer's disease; AGO; Argonaute proteins; AMPK; AMP-activated protein kinase; ANTs; adenine nucleotide translocators; AK; adenylate kinase; APP; amyloid-β precursor protein; ASD; autism spectrum disorder; CAT; catalase; CNS; central nervous syste
Autophagy in ischemic stroke
Keywords: 3-MA; 3-methyladenine; Aβ; amyloid β; AIF; apoptosis-inducing factor; Akt; protein kinase B; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; Atg; autophagy-related genes; ATP; adenosine 5â²-triphosphate; BBB; blood-brain ba
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
Foxo3 gene expression and oxidative status in beta-thalassemia minor subjects
Keywords: Beta-thalassemia trait; Oxidative stress; FoxO3; Thiobarbituric acid reactive species; Erythrocyte catalase activity;
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases
Keywords: ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)
Keywords: 9-1-1 complex; complex of Rad9 Rad1 and Hus1 proteins; A2E; N-retinylidene-N-retinylethanol-amine; AtRal; all-trans retinal; AMD; age-related macular degeneration; AMPK; AMP-activated protein kinase; Atg; autophagy-related gene; ATM; ataxia-telangiectasia
BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells
Keywords: Annexin V; FITC-conjugated annexinV; BCA; bicinchoninic acid; BNIP3; Bcl2/adenovirus E1B 19Â kDa protein-interacting protein 3; CBP; CREB-binding protein; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CHIP; chromatin immunoprecipitation; CHOP; CCAAT-en
The roles of subcellularly located EGFR in autophagy
Keywords: AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e
Research ReportTanshinol suppresses inflammatory factors in a rat model of vascular dementia and protects LPS-treated neurons via the MST1-FOXO3 signaling pathway
Keywords: Vascular dementia; Tanshinol; Inflammation; MST1; FOXO3;
The poly(ADP-ribosyl)ation of FoxO3 mediated by PARP1 participates in isoproterenol-induced cardiac hypertrophy
Keywords: ANF; atrial natriuretic factor; BNP; brain natriuretic polypeptide; FoxO3; forkhead box O3; HE; hematoxylin-eosin; IF; immunofluorescence; IHC; immunohistochemical; ISO; isoproterenol; NRCMs; neonatal rat cardiomyocytes; PARP1; poly(ADP-ribose) polymerase
SIRT6 suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy
Keywords: Atgs; autophagy-related genes; ANF; atrial natriuretic factor; BNP; brain natriuretic polypeptide; FoxO3; forkhead box O3; LC3; microtubule-associated protein 1 light chain 3; IF; immunofluorescence; NRCMs; neonatal rat cardiomyocytes; ISO; isoproterenol;
MiR-498 regulated FOXO3 expression and inhibited the proliferation of human ovarian cancer cells
Keywords: miR-498; Human ovarian cancer; FOXO3; Cell proliferation
Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish
Keywords: FOXO3; Erythroid differentiation; Globin; Zebrafish
Docosahexaenoic acid prevents palmitate-induced activation of proteolytic systems in C2C12 myotubes
Keywords: Palmitate; Docosahexaenoic acid; Muscle atrophy; Proteolysis; Macroautophagy; FoxO3
Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients
Keywords: Lymphocytes; Alzheimer's disease; p21; Apoptosis; Calmodulin; CaMKII; ERK1/2; FOXO3;
Regulation of Akt-mTOR, ubiquitin-proteasome and autophagy-lysosome pathways in response to formoterol administration in rat skeletal muscle
Keywords: Actb; actin beta; Atg; autophagy-related; Bnip3; BCL2/adenovirus E1B interacting protein 3; BSA; bovine serum albumin; COPD; chronic obstructive pulmonary disease; CREB; cAMP response element binding protein; EDL; extensor digitorum longus; eIF3-f; eukary
Activation of autophagy by globular adiponectin attenuates ethanol-induced apoptosis in HepG2 cells: Involvement of AMPK/FoxO3A axis
Keywords: Adiponectin; AMPK; Apoptosis; Autophagy; Ethanol; FoxO3;
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3
Keywords: Sirtuin; Mitochondrial biogenesis; PGC-1α; AMPK; FoxO3; mtTFA;
SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage
Keywords: BAEC; bovine aortic endothelial cell; CR; caloric restriction; EC; endothelial cell; HUVEC; human umbilical vein endothelial cell; OCR; oxygen consumption rate; ROS; reactive oxygen species; SIRT3; FOXO3; Mitochondrial homeostasis; Mitochondrial biogenesi
Exploratory analysis of activation of PTEN–PI3K pathway and downstream proteins in malignant pleural mesothelioma (MPM)
Keywords: FOXO3; Malignant pleural mesothelioma; PI3K; pS6; Prognostic factor
IKK-β mediates chemoresistance by sequestering FOXO3; A critical factor for cell survival and death
Keywords: FOXO3; IKK; Chemoresistance; Cell death; Breast cancer;
The anti-inflammatory and antioxidative effects of nicotinamide, a vitamin B3 derivative, are elicited by FoxO3 in human gestational tissues: implications for preterm birth
Keywords: Nicotinamide; Vitamin B3; Cytokines; Prostaglandins; Oxidative stress; FoxO3; Parturition
Analysis of FOXO3 mutation in 114 Chinese women with premature ovarian failure
Keywords: female infertility; FOXO3; premature ovarian failure
Expression and Localisation of FoxO3 and FoxO4 in Human Placenta and Fetal Membranes
Keywords: Placenta; Fetal membranes; FoxO3; FoxO4; Fetal membrane rupture