Keywords: Centenarians; Longevity; Meta-analysis; ACE; APOE; FOXO3A;
مقالات ISI (ترجمه نشده)
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Keywords: Obesity; Paraventricular nucleus; Cystathionine β synthase; Hydrogen sulfide; Leptin; FOXO3a;
Keywords: 4- Shogaol (PubChem CID: 9794897); 6- Shogaol (PubChem CID: 5281794); Apigenin (PubChem CID: 5280443); Berberine (PubChem CID: 2353); Bergamottin (PubChem CID: 5471349); Caffeic acid (PubChem CID: 689043)Capsaicin (PubChem CID: 1548943); Cardamonin (PubCh
Keywords: As(III); arsenite; As(V); arsenate; MMA; monomethylarsonic acid; Nox 2; NADPH oxidase; NOS; nitric oxide synthases; ETC; electron transport chain; WAT; white adipose tissue; BAT; brown adipose Tissue; UCP; uncoupling protein; α-KDGH; α-ketoglutarate deh
Keywords: EGFR; Epidermal growth factor receptor; TP53; Tumor protein p53; KRAS; Kirsten rat carcoma viral oncogene; ALK; Anaplastic lymphoma kinase; RTK; Protein receptor tyrosine kinase; TKI; Tyrosine kinase inhibitor; PI3K; Phosphatidylinositol 3-kinase; NSCLC;
Keywords: Ovarian cancer; Chemotherapy resistance; Natural compounds; Autophagy; Apoptosis; Ovarian cancer stem-like cells; ABCG2; ATP-binding cassette G2; AE; Amla extracts; Akt; protein kinase B; ALDH1; aldehyde dehydrogenase 1; ARE; antioxidant-response element;
Keywords: AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: OS; oxidative stress; CNS; central nervous system; ROS; reactive oxygen species; SOD; superoxide dismutase; CAT; catalase; Cu; copper; Zn; zinc; Mn; manganese; Fe; iron; Ni; nickel; DA; dopamine; PHOX; NADPH oxidase; Nrf2; nuclear factor erythroid 2-relat
Keywords: Akt; serine/threonine-protein kinase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; Diab; diabetic; eNOS; endothelial nitric oxide synthase; FOXO3a; forkhead box O3a; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLUT4; glucose tran
Keywords: AceCS2; acetyl-CoA synthetase 2; ADP; adenosine diphosphate; CPS1; carbamoyl phosphate synthetase 1; CPT1; carnitine palmitoyltransferase I; CR; calorie restriction; FOXO3a; forkhead box 03a; GDH; glutamate dehydrogenase; HeLa; human cervical carcinoma ce
Keywords: AKT/PKB; protein kinase B; AMPK; adenosine monophosphate kinase; BSA; bovine serum albumin; CaMKK; calcium/calmodulin-dependent protein kinase; CEUA; Committee for Ethical Use of Animals; DEX; dexamethasone; EDTA; ethylenediaminetetraacetic acid; FHL; fle
Keywords: AICAR; 5â²aminoimidazole-4-carboxyamide-ribonucleoside; AD; Alzheimer's disease; ATF-2; activating transcription factor-2; AMPK; AMP-activated protein kinase; Bnip3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BnipL/Nix; BCL2/adenovirus E1B 19Â
Keywords: CMFDA; 5-chloromethylfluorescein diacetate; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; DNA; deoxyribonucleic acid; DPBS; Dulbecco's Phosphate Buffered Saline; DRAQ5®; 1,5-bis{[2-(di-methylamino) ethyl]amino}-4,8-dihydroxyanthracene
Keywords: AKT/PKB; protein kinase B; Apaf-1; apoptotic protease activating factor 1; ERK; extracellular signal-regulated kinase; ETC; electron transport chain; FADD; Fas-associated death domain; FOXO3a; forkhead-box protein O3a; HK; hexokinase; HNE-1; Na+/H+ exchan
Keywords: BRAF; B-Raf protein; BRD4; bromodomain-containing protein 4; CDK6; cyclin-dependent kinase 6; ERBB1; epidermal growth factor receptor; ERG; ETS-family oncogenic transcription factor; ERK; extracellular signal regulated protein kinase; FOS; FBJ murine oste
Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-
MicroRNA-34c regulates porcine granulosa cell function by targeting forkhead box O3a
Keywords: porcine; microRNA-34c; FoxO3a; granulosa cell function;
FOXO3a Reverses the Cisplatin Resistance in Ovarian Cancer
Keywords: FOXO3a; Platinum drug resistance; Ovarian cancer;
N-acetyl-l-cysteine ameliorates the PM2.5-induced oxidative stress by regulating SIRT-1 in rats
Keywords: Sirtuin-1; FOXO3a; PM2.5; N-acetyl-l-cysteine; Oxidative stress;
FoxO3a Regulates Inflammation-induced Autophagy in Odontoblasts
Keywords: Autophagy; FoxO3a; inflammation; odontoblast;
SIRT3-mediated cardiac remodeling/repair following myocardial infarction
Keywords: MI; myocardial infarction; HIF; hypoxia inducible factor-1α; SOD2; superoxide dismutase; FOXO3A; forkhead box O3a; OPA1; optic atrophy 1; MMPs; matrix metalloproteinases; TGF-β; transforming growth factor-β; PARP-1; poly (ADP ribose)- polymerase 1; VEG
Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice
Keywords: Green tea; (-)-Epigallocatechin-3-gallate; Hepatotoxicity; Oxidative stress; Mitochondria; ALT; alanine aminotransferase; AST; aspartate aminotransferase; MT-Co2; cytochrome oxidase subunit II; EGCG; (-)epigallocatechin-3-gallate; FOXO3a; forkhead box O3a
Research reportSuppression of FoxO3a attenuates neurobehavioral deficits after traumatic brain injury through inhibiting neuronal autophagy
Keywords: Traumatic brain injury; Neurobehavioral deficits; FoxO3a; Autophagy; Neuron;
Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress
Keywords: AMPK; adenosine 5'-monophosphate (AMP)-activated protein kinase; CK; creatine kinase; DAPI; 4',6'-Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; FXR; farnesoid X receptor; GCLM; glutamatecysteine ligase mod
Botryosphaeran reduces obesity, hepatic steatosis, dyslipidaemia, insulin resistance and glucose intolerance in diet-induced obese rats
Keywords: Botryosphaeria rhodina MAMB-05; (1â¯ââ¯3)(1â¯ââ¯6)-β-D-Glucan; AMPK; FOXO3a;
β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models
Keywords: AICD; FOXO3a; γ-Secretase; Mitochondrial dysfunction; Mitophagy; Parkin; Pink-1; Presenilins; 3xTgAD Mice;
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2
Keywords: ARE; antioxidant response element; CK; creatine kinase; DAPI; 4â²,6â²- Diamidino-2-phenylindole; DOX; doxorubicin; ECG; electrocardiograms; FOXO3a; Forkhead box O3; GCLM; glutamate-cysteine ligase modifier subunit; GSH; glutathione; GSH-Px; glutathione
FGF21 protects human umbilical vein endothelial cells against high glucose-induced apoptosis via PI3K/Akt/Fox3a signaling pathway
Keywords: FGF21; eNOS; Oxidative stress; Apoptosis; FoxO3a; Akt;
A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding gene
Keywords: aa; amino acid(s); bp; base pairs; Cas9; CRISPR associated protein 9; cDNA; DNA complementary to RNA; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DMSO; dimethylsulfoxide; Dox; doxycycline; dsDNA; double stranded DNA; FOXO; forkhead
Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts
Keywords: miRNAs; microRNAs; Ogn; osteoglycin/mimecan; 3â²UTR; 3â² untranslated region; HF; heart failure; Socs1; suppressor of cytokine signaling 1; FoxO3a; Forkhead box O3a; ECM; extracellular matrix; GM; growth medium; RIN; RNA integrity number; PBS; Phosphate
Chronic exposure of the RAW246.7 macrophage cell line to H2O2 leads to increased catalase expression
Keywords: ROS; reactive oxygen species; GSH; glutathione; SOD; superoxide dismutase; PTPs; protein tyrosine phosphatases; NEM; N-ethylmaleimide; DTNB; 5,5-dithio-bis-(2-nitrobenzoic acid); PMA; phorbol 12-myristate 13-acetate; ASK1; apoptosis signal-regulating kina
Activation of FOXO3a reverses 5-Fluorouracil resistance in human breast cancer cells
Keywords: Breast cancer; Drug resistance; Tic10; FOXO3a;
SIRT2 reduces actin polymerization and cell migration through deacetylation and degradation of HSP90
Keywords: APC/C; anaphase-promoting complex/cyclosome; CHX; cycloheximide; EMT; epithelial-mesenchymal transition; F-actin; filamentous actin; FOXO3a; forkhead box O3a; G-actin; globular actin; HCC; hepatocellular carcinoma; HSP90; heat shock protein 90; HOXA10; ho
Role of miRNAs in cell signaling of cancer associated fibroblasts
Keywords: ATG; autophagy related; CAF; cancer associated fibroblasts; CCL; C-C motif chemokine ligand; CDK2; cyclin-dependentkinase 2; CXCL; chemokine(C-X-C motif) ligand; DRAM; damage-regulated autophagy modulator; ECM; extracellular matrix; EMT; epithelialto mese
FOXO3a-dependent up-regulation of Mxi1-0 promotes hypoxia-induced apoptosis in endothelial cells
Keywords: Mxi1-0; FOXO3a; Hypoxia; Apoptosis; Endothelial cells;
Endoplasmic reticulum stress impairs cardiomyocyte contractility through JNK-dependent upregulation of BNIP3
Keywords: Endoplasmic reticulum; Cardiac dysfunction; Myocardial infarction; JNK; BNIP3; FOXO3a;
Overexpression of Sirt1 in mesenchymal stem cells protects against bone loss in mice by FOXO3a deacetylation and oxidative stress inhibition
Keywords: ALP; alkaline phosphatase; Bmi-1; B cell-specific Moloney murine leukemia virus integration site 1; Bmi-1â/â; Bmi1 deficiency; Bmi-1+/â; Bmi-1 heterozygous; Col-I; type I collagen; Col-II; type II collagen; FOXO; Forkhead box O; GPX1; Glutathione pe
Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway
Keywords: ALP; Alkaline phosphatase; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; BGLAP; bone gamma carboxyglutamate protein; BM-MSCs; bone marrow-derived mesenchymal stem cells; CAT; catalase; CC; Compound C; CCK-8; cell counting kit-8; C
miR-1307 promotes the proliferation of prostate cancer by targeting FOXO3A
Keywords: miR-1307; Prostate cancer; FOXO3A; Cell proliferation;
Effect of Sirtuin 1 inhibition on matrix metalloproteinase 2 and Forkhead box O3a expression in breast cancer cells
Keywords: Breast cancer; FOXO3a; MMP2; SIRT1; Sirtinol;
Maternal diabetes and high glucose in vitro trigger Sca1+ cardiac progenitor cell apoptosis through FoxO3a
Keywords: Sca1+ cardiac progenitor cells; Maternal diabetes; Diabetic embryopathy; Apoptosis; FoxO3a; High glucose;
Protein kinase C downregulation induces senescence via FoxO3a inhibition in HCT116 and HEK293Â cells
Keywords: Senescence; Protein kinase C; FoxO3a; ROS; p53; p21Cip1/WAF1; CK2; protein kinase CK2; DCFDA; dichlorofluorescein diacetate; DHE; dihydroethidium; DMEM; Dulbecco's modified Eagle's media; ECL; enhanced chemiluminescence; FoxO; forkhead homeobox type O; HA
TRIP6 promotes cell proliferation in hepatocellular carcinoma via suppression of FOXO3a
Keywords: TRIP6; HCC; Proliferation; FOXO3a;
MiR-34a/sirtuin-1/foxo3a is involved in genistein protecting against ox-LDL-induced oxidative damage in HUVECs
Keywords: Genistein; Atherosclerosis; Oxidative damage; miR-34a; Sirtuin-1; foxo3a;
Anti-photoaging potential of propolis extract in UVB-irradiated human dermal fibroblasts through increasing the expression of FOXO3A and NGF genes
Keywords: Propolis; Human dermal fibroblast; Photoaging; NGF; FOXO3A;
AMPK activation ameliorates D-GalN/LPS-induced acute liver failure by upregulating Foxo3A to induce autophagy
Keywords: AMPK; Acute liver failure; Foxo3A; Autophagy;
Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMA
Keywords: Betulinic acid derivative B10; Glioma; Apoptosis; SIRT1; FOXO3a; Bim/PUMA;
Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells
Keywords: ACC1; acetyl-CoA carboxylase; AKT; protein kinase B, PKB; CAII; carbonic anhydrase II; CHP1; calcineurin B homologous protein 1; ER; estrogen receptor; ERK1/2; extracellular signal-regulated kinase 1/2; ERM; ezrin-radixin-moesin; FOXO3a; forkhead box O3a;
Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells
Keywords: autophagy; FOXO3a; ginsenoside; KG-135; lung cancer;
Testosterone modulates FoxO3a and p53-related genes to protect C2C12 skeletal muscle cells against apoptosis
Keywords: Apoptosis; Testosterone; Skeletal muscle; p53-Regulated genes; FoxO3a;