Keywords: غربالگری قطعه; High throughput screening; Fragment screening; Drug discovery; Chemical biology; Acoustic droplet ejection; In situ X-ray data collection; Crystallography; Synchrotron radiation;
مقالات ISI غربالگری قطعه (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: غربالگری قطعه; X-ray crystallography; Fragment screening; HIV; Influenza; BpGCDH; B. pseudomallei glutaryl-CoA dehydrogenase; DHNA; 7,8-dihydroneopterin aldolase; DMSO; dimethylsulfoxide; FBDD; fragment-based drug discovery; HCV; hepatitis C virus; HIV; human immunodef
Keywords: غربالگری قطعه; Glycogen Phosphorylase a; Fragment screening; Molecular docking; Thiazoline; Tetrahydropyrimidine; HeterocycleUXKJQFPDYOBGOV-UHFFFAOYSA-N; OBBQKJAKOJDAOE-UHFFFAOYSA-N; NPOKCMCYEADRJN-UHFFFAOYSA-N; ZJGPNHWFWJZYHJ-VIFPVBQESA-N; BHIDYSDDEHERMI-UHFFFAOYSA-N
Keywords: غربالگری قطعه; Fragment screening; Surface plasmon resonance; Focal adhesion kinase; X-ray structure; DFG-out;
Fragment screening for drug leads by weak affinity chromatography (WAC-MS)
Keywords: غربالگری قطعه; 3-ABA; 3-aminobenzamidine; 4-ABA; 4-aminobenzamidine; AmAc; ammonium acetate; APCI; atmospheric pressure chemical ionization; AQP1; human aquaporin-1; BA; benzamidine; BCA; bicinchoninic acid; CMC; critical micelle concentration; DMSO; dimethyl sulfoxide;
Methylpyrrole inhibitors of BET bromodomains
Keywords: غربالگری قطعه; BET proteins; Bromodomain; Fragment screening;
Virtual fragment screening on GPCRs: A case study on dopamine D3 and histamine H4 receptors
Keywords: غربالگری قطعه; Fragment screening; Fragment docking; Virtual screening; Ensemble docking; G protein-coupled receptors; Dopamine D3 receptor; Histamine H4 receptorGPCR, G protein-coupled receptor; FBLD, fragment-based lead discovery; LE, ligand efficiency; LELP, ligand-e
Fragment screening by SPR and advanced application to GPCRs
Keywords: غربالگری قطعه; Surface plasmon resonance; Fragment screening; GPCRs; G-protein coupled receptors; Biophysical screening; Membrane proteins; SPR;
Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei
Keywords: غربالگری قطعه; Fragment screening; MEP pathway; IspF; Non-mevalonate; Anti-infective; SPR;
The use of virtual screening and differential scanning fluorimetry for the rapid identification of fragments active against MEK1
Keywords: غربالگری قطعه; Fragment screening; Virtual screening; Differential scanning fluorimetry; MEK1;
Discovery of benzothiazole guanidines as novel inhibitors of thrombin and trypsin IV
Keywords: غربالگری قطعه; Thrombin; Trypsin IV; Benzothiazole guanidine; WaterLOGSY; Fragment screening
Thieno[3,2-d]pyrimidin-4(3H)-one derivatives as PDK1 inhibitors discovered by fragment-based screening
Keywords: غربالگری قطعه; 3-Phosphoinositide dependent protein kinase-1 (PDK1); Fragment screening; Kinase inhibitor design; Ligand efficiency;
High concentration electrophysiology-based fragment screen: Discovery of novel acid-sensing ion channel 3 (ASIC3) inhibitors
Keywords: غربالگری قطعه; Acid-sensing ion channel 3; Fragment screening; Electrophysiology
Non-covalent inhibitors of rhinovirus 3C protease
Keywords: غربالگری قطعه; Non-covalent inhibition; Rhinovirus 3C protease; Cysteine protease; Fragment screening
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors
Keywords: غربالگری قطعه; Enzyme, Kinase; Inhibitor; Benzofuran; X-ray structure; Structure based design; Salt-bridge; Hydrogen bond interaction; Synthesis; Carboxylic acid; Amine; Basicity; SPR; Medicinal chemistry; Fragment screening
Weak affinity chromatography as a new approach for fragment screening in drug discovery
Keywords: غربالگری قطعه; Fragment screening; Mass spectrometry; Drug discovery; Drug design; Weak affinity chromatography; Fragment-based drug discovery
A fluorescence correlation spectroscopy-based assay for fragment screening of slowly inhibiting protein–peptide interaction inhibitors
Keywords: غربالگری قطعه; FCS; Protein–protein interaction inhibitor; FBDD; Fragment screening
19F NMR chemical shift prediction with fluorine fingerprint descriptor
Keywords: غربالگری قطعه; Fluorine; Chemical shift; NMR; Fragment screening
Tyramine fragment binding to BACE-1
Keywords: غربالگری قطعه; BACE-1; Alzheimer; Fragment screening; Surface plasmon resonance; X-ray structure; Structure-based design; Tyramine
Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors
Keywords: غربالگری قطعه; HCV; NS5b; Fragment screening; Protein crystallography
High throughput solubility determination with application to selection of compounds for fragment screening
Keywords: غربالگری قطعه; Solubility; Physicochemical properties; UV/vis spectroscopy; Automation; Structure–property relationship; Fragment screening; Fragment-based drug discovery; Screening library