دانلود مقالات ISI درباره Ftd + ترجمه فارسی

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Origin of α-mannosidase activity in CSF

Keywords: AD; Alzheimer's disease; BBB; blood-brain barrier; CSF; cerebrospinal fluid; DLB; dementia with Lewy bodies; ERT; enzyme replacement therapy; EV; extracellular vesicles; FTD; Fronto-Temporal Dementia; LP; lumbar puncture; MAN2B1; lysosomal α-mannosidas

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Als and Ftd: Insights into the disease mechanisms and therapeutic targets

Keywords: ALS; Dementia; FTD; Genetics; Motor neuron disease; TDP-43; Riluzole; Stem cells;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Intrafamilial variable phenotype including corticobasal syndrome in a family with p.P301L mutation in the MAPT gene: first report in South America

Keywords: FTD; MAPT; P301L; Cognition; CBS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis

Keywords: Motor neuron disease; X-linked ALS; FTD; Proteolysis regulation; Incomplete penetrance; X inactivation; Dimerization;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

Keywords: PS; Presymptomatic; S; Symptomatic; FTD; Frontotemporal dementia; WMH; White matter hyperintensity; IQR; Inter Quartile Range; CI; Confidence interval; TIV; Total Intracranial volume;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

DCTN1-related neurodegeneration: Perry syndrome and beyond

Keywords: Atypical parkinsonism; DCTN1; Dynactin; FTD; Genetics; TDP-43; Perry syndrome; PSP; Review; ALS; amyotrophic lateral sclerosis; CAP-Gly; cytoskeleton-associated protein, glycine-rich; DCTN1; dynactin 1; FTD; frontotemporal dementia; HD; Huntington's dis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration

Keywords: 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose; AD; Alzheimer's disease; CBD; Corticobasal Degeneration; CSF; Cerebrospinal Fluid; DHE; Dihydroethidium; ETC; Electron Transport Chain; FCCP; Carbonyl cyanide-4-(trifluoromethoxy)pheny

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers

Keywords: ALS; amyotrophic lateral sclerosis; bvFTD; behavioral variant frontotemporal dementia; FTD; frontotemporal dementia; CDR; Clinical Dementia Rating scale; DMN; default mode network; FA; fractional anisotropy; fMRI; functional MRI; FWE; familywise error; HC

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene

Keywords: C9orf72; ALS; FTD; Repeat expansion disease; RNA foci; Dipeptide repeat protein;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease

Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; TREM2; the triggering receptor expressed on myeloid cells 2 gene; VPS35; the vacuolar protein sorting 35 gene; EIF4G1; the eukaryotic translation initiation factor 4-gamma 1 gene; S100B; the S100 calci

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Methylation of C9orf72 expansion reduces RNA foci formation and dipeptide-repeat proteins expression in cells

Keywords: FTD; frontotemporal dementia; ALS; amyotrophic lateral sclerosis; C9orf72; chromosome 9 open reading frame 72; c9FTD/ALS; FTD/ALS caused by expansion in C9orf72 gene; RAN translation; repeat-associated non-ATG translation; DPR; dipeptide-repeat protein; p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

TREMs in Alzheimer's disease: Genetic and clinical investigations

Keywords: AD; Alzheimer's disease; TREM; Triggering receptor expressed on myeloid cells; TREML; TREM like transcript; NHD; Nasu-Hakola disease; NFTs; neurofibrillary tangles; p-tau; hyperphosphorylated tau; GWAS; genome-wide association studies; sTREM2; soluble f

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A rare mutation in MYH7 gene occurs with overlapping phenotype

Keywords: MYH7; Left ventricular non-compation; Cardiomyopathy; FTD; Laing Distal Myopathy; Overlapping syndrome; ACTA1; actin 1; CPK; creatine phosphokinase; CFTD; Congenital Fiber Type Disproportion; COX; cytochrome C oxidase; DES; desmin; EMG; electromyography;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Linkage and whole genome sequencing identify a locus on 6q25-26 for formal thought disorder and implicate MEF2A regulation

Keywords: CSLS; Copenhagen schizophrenia linkage study; FTD; Formal thought disorder; IGV; Integrative genomics viewer; LOD; Logarithm of odds; MAF; Minor allele frequency; sTRAP; The SNP transcription factor affinity prediction; TDI; Thought disorder index; WGS; w

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Research ReportCharacterisation of multiple regulatory domains spanning the major transcriptional start site of the FUS gene, a candidate gene for motor neurone disease

Keywords: Evolutionary conserved domains; Reporter gene assays; Chick embryo model; ALS; Parkinson׳s disease; FTD;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research PaperEvidence for accelerated tauopathy in the retina of transgenic P301S tau mice exposed to repetitive mild traumatic brain injury

Keywords: AD; Alzheimer's disease; CTE; chronic traumatic encephalopathy; DAB; 3,3′-diaminobenzidine; FTD; frontotemporal degeneration; IA; impact acceleration; IHC; immunohistochemistry; mTBI; mild traumatic brain injury; NFL; National Football League; NSS; neur

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanism

Keywords: TDP-43; Loss-of-function; ALS; FTD; AD; Drosophila;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Biomarker development for C9orf72 repeat expansion in ALS

Keywords: C9orf72; ALS; Biomarker; FTD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Influence of socio-demographic features and apolipoprotein E epsilon 4 expression on the prevalence of dementia and cognitive impairment in a population of 70-74-year olds: The InveCe.Ab study

Keywords: MCI; mild cognitive impairment; CIND; cognitive impairment, no dementia; ApoE-ɛ4; apolipoprotein E- ɛ4; AD; Alzheimer's disease; VD; vascular dementia; DLB; dementia with Lewy bodies; FTD; frontotemporal dementia; DSM-IV-TR; Italian version of the Diagn

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Traumatic brain injury causes frontotemporal dementia and TDP-43 proteolysis

Keywords: ALS; amyotrophic lateral sclerosis; CI; confidence interval; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; HRs; hazard ratios; SARK; sarkosyl; TBI; traumatic brain injury; TDP-43; TAR-DNA binding protein 43; traumatic brain injury

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models

Keywords: RBPs; RNA-binding proteins; ALS; amyotrophic lateral sclerosis; FTD; frontotemporal dementia; HTS; high-throughput screening; F.C.; fold change; S.I.; splicing index; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; WB; Western blot; TDP-

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2015 سفارش ترجمه

Improving the knowledge of amyotrophic lateral sclerosis genetics: novel SOD1 and FUS variants

Keywords: ALS; FTD; SOD1; FUS; C9ORF72; TARDBP; Genetic screening;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Reduced frequency of T lymphocytes expressing CTLA-4 in frontotemporal dementia compared to Alzheimer's disease

Keywords: AD; Alzheimer Disease; APC; antigen presenting cell; bvFTD; behavioural-variant frontotemporal dementia; CD80; B7-1; CD86; B7-2; CNS; central nervous system; CTLA-4; cytotoxic T-lymphocyte antigen-4 or CD152; CTRL; control patients; FTD; Frontotemporal de

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Defining the association of TMEM106B variants among frontotemporal lobar degeneration patients with GRN mutations and C9orf72 repeat expansions

Keywords: FTD; FTD-ALS; GRN; TMEM106B; C9orf72; rs1990622; rs3173615;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

ReviewFocality, stochasticity and neuroanatomic propagation in ALS pathogenesis

Keywords: ALS; amyotrophic lateral sclerosis; FALS; familial ALS; FTD; frontotemporal dementia; LMN; lower motor neuron; PLS; primary lateral sclerosis; PMA; progressive muscular atrophy; SALS; sporadic ALS; UMN; upper motor neuron; ALS; PLS; PMA; Motor neuron dise

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

SQSTM1 mutations - Bridging Paget disease of bone and ALS/FTLD

Keywords: ALS; amyotrophic lateral sclerosis; aPKC; atypical protein kinase C; C9orf72; chromosome 9 open reading frame 72; FTD; frontotemporal dementia; FTLD; frontotemporal lobar degeneration; FUS/TLS; fused in sarcoma/translocated in liposarcoma; GWAS; genome-wi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

HDL and cognition in neurodegenerative disorders

Keywords: ABC; ATP-binding cassette transporter; AD; Alzheimer's disease; Akt; protein kinase B; ALS; amyotrophic lateral sclerosis; apo; apolipoprotein; Aβ; amyloid-β protein; BBB; blood-brain barrier; CAA; cerebral amyloid angiopathy; CE; cholesterol ester; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2014 سفارش ترجمه

The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier)

Keywords: Frontotemporal degeneration; FTD; Alzheimer's disease; AD; Progressive supranuclear palsy; Corticobasal degeneration; Treatment; Clinical trial; Biomarker; Drug development;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

ALS patients with mutations in the SOD1 gene have an unique metabolomic profile in the cerebrospinal fluid compared with ALS patients without mutations

Keywords: ALS; amyotrophic lateral sclerosis; FTD; fronto-temporal dementia; NPH; normal pressure hydrocephalus; PBP; progressive bulbar palsy; SBMA; spinobulbar muscular atrophy; SALS; sporadic ALS; FALS; familial ALS; wt; wild-type SOD1 genotype; ALSFRS; ALS Funt

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

ReviewTDP-43 aggregation in neurodegeneration: Are stress granules the key?

Keywords: TARDBP; TDP-43; FUS; Stress granule; FTD; FTLD; Frontotemporal lobar degeneration; ALS; Amyotrophic lateral sclerosis; Neurodegeneration; Independent model; Precursor model;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Structural and functional characterization of H2 haplotype MAPT promoter: Unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease

Keywords: AD; Alzheimer's disease; AP; activator protein; APOE; apolipoprotein E gene; APP; amyloid β peptide precursor gene; Aβ; amyloid β peptide; bp; base-pair; C/EBP; CCAAT/enhancer binding protein; C6; rat glioblastoma cells; CAT; chloramphenicol acetyltran

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Neurodegeneration the RNA way

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Aβ42; amyloid β - 42 amino acids; CUGBP1; CUG binding protein 1; DM1; myotonic dystrophy type 1; DM2; myotonic dystrophy type 2; FTD; frontotemporal dementia;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

AMSH is required to degrade ubiquitinated proteins in the central nervous system

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMSH; associated molecule with the SH3 domain of STAM; AMPAR; α-amino-3-hydroxy-5-methyl-isoxazolepropionic acid receptor; CHMP; chromatin modifying protein; ESCRT; endosomal sorting complexe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of a Randomized Controlled Trial in the Management of Chronic Lower Back Pain in a French Automotive Industry: An Observational Study

Keywords: Exercise; Low back pain; Physical therapy modalities; Rehabilitation; Workplace; CONT; control group; Danx-dep; impact of work on anxiety and depression symptoms; Ddaily; impact of pain on daily activity; Dsocial; impact of pain on social activity; Dwork-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Dementia induces correlated reductions in white matter integrity and cortical thickness: A multivariate neuroimaging study with sparse canonical correlation analysis

Keywords: Dementia; Multivariate; Correlation; Diffusion tensor; Cortical thickness; AD; FTD; Canonical correlation;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation

Keywords: APP; amyloid precursor protein; Aβ; amyloid peptide; AV10; autophagic vacuoles; AV20; autolysosomes; CHIP; C-terminal HSP70 interacting protein; CBD; corticobasal degeneration; DA; dopamine; DAT; dopamine transport; FTD; frontotemporal dementia; HSP; hea

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Registration based cortical thickness measurement

Keywords: Cortex; Thickness; Diffeomorphism; Euclidean distance; Deformable models; Longitudinal; FTD;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein–protein interaction

Keywords: Calcium; Mouse; Gamma secretase; Neurodegenerative disease; Ion channel gating; Presenilin-1; Alzheimer's disease; Sporadic AD; Familial AD; FAD; FTD

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Universal grammar in the frontotemporal dementia spectrum

Keywords: FTD; Syntax; Comprehension; CBDS; PSP; Language impairment;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Distinct patterns of olfactory impairment in Alzheimer's disease, semantic dementia, frontotemporal dementia, and corticobasal degeneration

Keywords: SPSB; Odour Perception and Semantic Battery; AD; Alzheimer's disease; FTD; frontotemporal dementia; SD; semantic dementia; CBD; corticobasal degeneration; Neuropsychology; Smell; Odour perception; Odour semantics; Neurodegeneration; Olfactory cortex;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Frontotemporal dementia as a neural system disease

Keywords: Dementia; FTD; Frontotemporal dementia; Behavior; VBM; Morphometry; Limbic system;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

ALS/FTLD-linked TDP-43 regulates neurite morphology and cell survival in differentiated neurons

Keywords: FTD; ALS; TDP-43; Neurite; Cell survival;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

MRI identifies MCI subtypes: vascular versus neurodegenerative

Keywords: ADL; activities of daily living; ADRDA; Alzheimer Disease and Related Disorders Association; CCSE; Cognitive Capacity Screening Examination; CMC; Combined Mini-Mental and Cognitive Capacity Screening Examinations; CSF; cerebrospinal fluid; DAT; dementia o

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Functional Genomics meets neurodegenerative disorders

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; CSF; cerebrospinal fluid; DIGE; difference in-gel electrophoresis; ESI; electrospray ionization; EST; expressed sequence tag; FTD; frontotemporal dementia; HPLC; high-pressure liquid chromatogra

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism

Keywords: DEP; diesel exhaust particles; PM; particulate matter; PD; Parkinson's disease; AD; Alzheimer's disease; ROS; reactive oxygen species; NO; nitric oxide; TNFα; tumor necrosis factor-alpha; TH; tyrosine hydroxylase; Aβ; beta-amyloid; LPS; lipopolysacharid

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2005 سفارش ترجمه