دانلود مقالات ISI درباره Gck + ترجمه فارسی

برنامه ریزی متابولیسم گلوکز در نوزادان قزل آلای رنگین کمان پس از هیپوکسی مزمن در مرحله تخمک گذاری همراه با یک کربوهیدرات رژیم غذایی بالا: مصرف پروتئین در اولین بار تغذیه

Programming of the glucose metabolism in rainbow trout juveniles after chronic hypoxia at hatching stage combined with a high dietary carbohydrate: Protein ratios intake at first-feeding

Keywords: gck; glucokinase; pfkm; phosphofructokinase (muscle); pfkl; phosphofructokinase (liver); pkm; pyruvate kinase (muscle); pklr; pyruvate kinase (liver and red blood cell); pck; phosphoenol pyruvate carboxykinases (cytosolic pck1 and mitochondrial pck2); fbp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

اختلالات جنسی در ایجاد استئاتوز کبدی در چاقی ناشی از رژیم غذایی در کافه تریا در موش های جوان

Sex differences in the development of hepatic steatosis in cafeteria diet-induced obesity in young mice

Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms

Keywords: TP; tea polyphenols; DD; constant darkness; SCN; suprachiasmatic nucleus; LD; light-dark; CLOCK; circadian locomotor output cycles kaput; BMAL1; brain and muscle arnt-like protein-1; CRY; cryptochromes; REV-ERB; -; RORs; RAR-related orphan receptors; PE

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

اثرات فردی سلنوکوپات های مختلف بر پروتئوم کبدی و متابولیسم انرژی موش

Individual effects of different selenocompounds on the hepatic proteome and energy metabolism of mice

Keywords: AKT; protein kinase B; ARE; anti-oxidant response elements; CCB; colloidal Coomassie Blue; DIGE; difference gel electrophoresis; ERK; extracellular regulated kinase; Fasn; fatty acid synthase; Gck; glucokinase; Gpx/GPx; glutathione peroxidase; GS; glutath

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

سلولهای اندوتلیوم ریتوکولوم-میتوکندری سیگنالینگ در بیماریهای متابولیک کبدی

Endoplasmic reticulum-mitochondria calcium signaling in hepatic metabolic diseases

Keywords: ATP; adenosine triphosphate; Ca2+;  calcium; CamK; calmodulin-dependent kinase; ChREBP; carbohydrate response element binding protein; CypD; cylophilin D; DGAT2; diacylglycerol acyltransferase 2; ER; endoplasmic reticulum; FOXO1; Forkhead box O1; G6P; gl

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

مومیایی لیمو: یک درمان گیاهی امیدبخش برای بیماران مبتلا به هیپرلیپیدمی مرزی - یک کارآزمایی بالینی تصادفی دوسوکور پلاسبو

Lemon balm: A promising herbal therapy for patients with borderline hyperlipidemia-A randomized double-blind placebo-controlled clinical trial

Keywords: ALT; alanine transaminase; AST; aspartate transaminase; FBG; fasting blood glucose; GCK; glucokinase; G6Pase; glucose-6-phosphatase; HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; LBEO; lemon balm essential oil; PPAR; peroxisome proliferator-activated

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

درمان بزرگسالان جوان با دیابت نوع 2 یا دیابت مونوژنیک

Treating young adults with type 2 diabetes or monogenic diabetes

Keywords: monogenic diabetes; young type 2 diabetes; personalised medicine; CRP; C-reactive protein; HNF1A; hepatocyte nuclear factor 1 alpha; HNF4A; hepatocyte nuclear factor 4 alpha; HNF1B; hepatocyte nuclear factor 1 beta; GCK; glucokinase; IPSAD; International

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

بیان ژن های جهانی انتقال ثانویه در طول رشد پانکراس

The global gene expression profile of the secondary transition during pancreatic development

Keywords: 2210010C04Rik; RIKEN cDNA 2210010C04 gene; 5330417C22Rik; RIKEN cDNA 5330417C22 gene; A1AT; alpha1-antitrypsin; Ago1; argonaute RISC catalytic component 1; Amy2a5; amylase 2a5; Amy2b; amylase, alpha 2B; AP1/JUN; jun proto-oncogene; Bmp; bone morphogenetic

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

پلی ساکارید ضد دیابت از منابع طبیعی: یک بررسی

Anti-diabetic polysaccharides from natural sources: A review

Keywords: AGE-RAGE; advanced glycation end products; AI; atherogenic index; AMPK; AMP-activated protein kinase; Ara; arabinose; Bax; pro-apoptotic Bcl2-associated X; Bcl-2; B-cell leukaemia/lymphoma 2; BG; blood glucose; CAT; catalase; Fuc; fucose; FBG; fasting blo

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

تغییرات مولکولی و عملکردی در بیان گلوکوکیناز در پیچیده عقب ماندگی مغز استخوان در یک مدل موش دیابت نوع 1

Molecular and functional changes in glucokinase expression in the brainstem dorsal vagal complex in a murine model of type 1 diabetes

Keywords: ACSF; artificial cerebrospinal fluid; CT; cycle threshold; DMV; dorsal motor nucleus of the vagus; EDTA; Ethylenediaminetetraacetic acid; EGFP; enhanced green fluorescent protein; EPSC; excitatory postsynaptic current; GA; glucosamine; GCK; glucokinase; I

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

آناگلیپتین مهار کننده دیپپتیدیل پپتیداز 4 موجب کاهش دیابت در موشهای مبتلا به کمبود گلوکوکیناز در رژیم غذایی با چربی بالا

Dipeptidyl peptidase-4 inhibitor anagliptin ameliorates diabetes in mice with haploinsufficiency of glucokinase on a high-fat diet

Keywords: DPP-4; dipeptidyl peptidase-4; GLP-1; glucagon-like peptide-1; IRS-2; insulin receptor substrate-2; CREB; cAMP response element-binding protein; Gck; glucokinase; GIR; glucose infusion rate(s); EGP; endogenous glucose production; Rd; rate of glucose disap

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Maturity Onset Diabetes of the Young (MODY) in Tunisia: Low frequencies of GCK and HNF1A mutations

Keywords: Apo A; apolipoprotein A; Apo B; apolipoprotein B; BMI; body mass index; DHPLC; Denaturing High Performance Liquid Chromatography; GAD; Anti-Glutamic acid Decarboxylase; HbA1c; glycated hemoglobin; HDL-C; high-density lipoprotein cholesterol; HLA-DRB1; HLA

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Consumption of the edible sea urchin Mesocentrotus nudus attenuates body weight gain and hepatic lipid accumulation in mice

Keywords: Sea urchin; Polyunsaturated fatty acid; Obesity; Non-alcoholic fatty liver disease; Uncoupling protein-1; AA; arachidonic acid; Akt 1; thymoma viral proto-oncogene 1; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BAT; brown adipose tissu

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Functional characterization of MODY2 mutations in the nuclear export signal of glucokinase

Keywords: CRM1; Chromosome Region Maintenance 1; F1P; fructose 1-phosphate; F6P; fructose 6-phosphate; GCK; glucokinase; GFP; green fluorescent protein; GKRP; glucokinase regulatory protein; GST; glutathione S-transferase; HA; hemagglutinin; NES; nuclear export sig

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Association of Native American ancestry and common variants in ACE, ADIPOR2, MTNR1B, GCK, TCF7L2 and FTO genes with glycemic traits in Colombian population

Keywords: ACE; angiotensin converting enzyme; MTNR1B; melatonin receptor 1B; GCK; glucokinase; TCF7L2; transcription factor 7 Like 2; FTO; alpha-ketoglutarate dependent dioxygenase; OR; odds ratio; IR; insulin resistance; T2D; type 2 diabetes; MS; metabolic syndrom

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease

Keywords: ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

High-fat diet alters PAS kinase regulation by fasting and feeding in liver

Keywords: ACC; acetyl CoA carboxylase; Akt/PKB; protein kinase B; CHREBP; carbohydrate-responsive element-binding protein; CPT1-A; carnitine palmitoyltransferase 1A; DAPI; 4,6-diamidino-2-phenylindole; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GCK;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Insights into pathogenesis of five novel GCK mutations identified in Chinese MODY patients

Keywords: GCK; Glucokinase; GKRP; Glucokinase regulatory protein; GSIS; Glucose-stimulated insulin secretion; G6P; Glucose-6-phosphate; GKAs; Glucokinase activators; MODY; Maturity-onset diabetes of the young; mGCK; Mutant GCK; OHA; Oral hypoglycaemic agents; WT GC

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver

Keywords: PXR; GLUT2; GCK; Impaired glucose tolerance; Diabetes;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

HDL-apoA-I induces the expression of angiopoietin like 4 (ANGPTL4) in endothelial cells via a PI3K/AKT/FOXO1 signaling pathway

Keywords: apoA-I; apolipoprotein A-I; ANGPTL4; angiopoietin like 4; CETP; cholesterol ester transfer protein; CHX; cycloheximide; CVD; cardiovascular disease; EBM; endothelial cell basal medium; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated kin

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Non-alcoholic fatty liver disease and its treatment with n-3 polyunsaturated fatty acids

Keywords: NAFLD; Omega-3 fatty acids; Fish oil; Algal oil; Insulin resistance; Metabolic syndrome; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; Apo; apolipoprotein; AST; aspartate aminotransferase; BMI; body mass index; ChREBP; carbohydrate response el

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Atorvastatin impaired glucose metabolism in C2C12 cells partly via inhibiting cholesterol-dependent glucose transporter 4 translocation

Keywords: ABC; ATP-binding cassette; Akt; Protein kinase B; AUC; area under the concentrationtime curve; BW; body weight; CMC; carboxyl methyl cellulose; ERK; extracellular-regulated protein kinase; GCK; glucokinase; GLUT2; glucose transporter 2; GLUT4; glucose tra

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Divergent synthesis of kinase inhibitor derivatives, leading to discovery of selective Gck inhibitors

Keywords: BAY 61-3606; Imidazo[1,2-c]pyrimidine; Gck; Indole; Kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice

Keywords: Selenium; DNA methylation; Liver; Lipogenesis; Srebf1; 5-mdC; 5-methyl-2′-deoxycytidine; Acaca; acetyl-CoA carboxylase α; CBS; cystathionine beta synthase; dC; 2′-deoxycytidine; DNMT; DNA methyltransferase; Fasn; fatty acid synthase; Gck; glucokinase

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

EGCG ameliorates diet-induced metabolic syndrome associating with the circadian clock

Keywords: EGCG; Epigallocatechin gallate; CLOCK; Circadian locomotor output cycles kaput; BMAL1; Brain and muscle arnt-like protein-1; CRY; Cryptochromes; PER; Period; SIRT1; Sirtuin 1; PGC1α; Peroxisome proliferator-activated receptor coactivator 1-α; IR; Insuli

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

TRPV4 regulates insulin mRNA expression and INS-1E cell death via ERK1/2 and NO-dependent mechanisms

Keywords: 4α-PDD; 4α-phorbol 12,13-didecanoate; BrdU; 5-bromo-2′-deoxyuridine; ERK1/2; extracellular signal-regulated kinase 1/2; GCK; glucokinase; GLP-1; glucagon-like peptide-1; hIAPP; human islet amyloid polypeptide; HPRT; hypoxanthine-guanine phosphoribos

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

SP and KLF Transcription Factors in Digestive Physiology and Diseases

Keywords: Specificity Protein; Krüppel-Like Factor; Digestive System; Cancer; Stem Cells; Proliferation; Differentiation; Development; Apoptosis; Cell Cycle; APC; adenomatous polyposis coli; BAX; B-cell lymphoma 2-like protein 4; BCL2; B-cell lymphoma 2; COX2; c

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2017 سفارش ترجمه

Involvement of pregnane X receptor in the impaired glucose utilization induced by atorvastatin in hepatocytes

Keywords: HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; PCN; pregnenolone-16α-carbonitrile; PXR; pregnane X receptor; GLUT2; glucose transporter 2; GCK; glucokinase; PDK2; pyruvate dehydrogenase kinase isoenzyme 2; PEPCK1; phosphoenolpyruvate carboxykinase 1; G6

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer

Keywords: Colorectal cancer; Cancer stem cell; Wnt signaling; Traf2- and Nck-interacting kinase (TNIK); Molecular targeting therapy; ABC; ATP-binding cassette; APC; adenomatous polyposis coli; CBP; cAMP response element binding protein (CREB)-binding protein; CK; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Elevated CpG island methylation of GCK gene predicts the risk of type 2 diabetes in Chinese males

Keywords: T2D, type 2 diabetes; TC, total cholesterol; TG, triglyceride; ALT, alanine aminotransferase; UA, uric acid; CGI, CpG islandType 2 diabetes; GCK; DNA methylation; CpG island; Gender

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck

Keywords: BPAB, isphenol A; Gck, glucokinase; ipGTTI, ntraperitoneal glucose tolerance tests; ipITTI, ntraperitoneal insulin tolerance tests; AUCA, rea-under-curveBisphenol A; F2 generation; Gck; DNA methylation; Sperm

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification, expression and bioactivity of hexokinase in amphioxus: Insights into evolution of vertebrate hexokinase genes

Keywords: ATP; adenosine triphosphate; Bp; base pair; DAB; diaminobenzidine; DNA; deoxyribonucleic acid; DTT; dithiothreitol; G6PDH; glucose-6-phosphate dehydrogenase; GCK; glucokinase; h; hour; HEPES; 4(2hydroxyethyl)-1-piperazine ethanesulfonic acid; HK; hexokina

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation

Keywords: BCA; bicinchoninic acid; DMEM; dulbecco's modified eagles medium; GCK; glucokinase gene; Glc; α-D-glucose; GKRP; glucokinase regulatory protein; HEK; human embryonic kidney; hGK; human glucokinase; IFG; impaired fasting glucose; MIN; mouse insulinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of toll-like receptor 3 function improves glucose tolerance and reduces liver steatosis in obese mice

Keywords: EMT; epithelial-mesenchymal transition; FDR; false discovery rate; FFA; free fatty acids; G6P; glucose-6-phosphotase; GcK; glucokinase; GO; gene ontology; GTT; glucose tolerance test; HDL-C; high-density lipoprotein cholesterol; HFD; high fat diet; HOMA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

A novel synonymous substitution in the GCK gene causes aberrant splicing in an Italian patient with GCK-MODY phenotype

Keywords: MODY; GCK; Synonymous mutation; RT-PCR; Cryptic splice site;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

ATF3 inhibits PDX-1-stimulated transactivation

Keywords: ATF3; activating transcription factor 3; ChIP; chromatin immunoprecipitation; ER; endoplasmic recticulum; GCK; glucokinase; PBE; PDX-1 binding element; PDX-1; pancreatic and duodenal homeobox factor-1; UPR; unfolded protein response; Type 2 diabetes; ER s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

ChREBP regulates Pdx-1 and other glucose-sensitive genes in pancreatic β-cells

Keywords: ARNT; aryl hydrocarbon receptor nuclear translocator; ChREBP; carbohydrate responsive element-binding protein; ChIP; chromatin immunoprecipitation; ChoRE; carbohydrate-responsive element; FAS; fatty acid synthase; GcK; glucokinase; GFP; green fluorescent

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Three novel mutations in MODY and its phenotype in three different Czech families

Keywords: MODY, maturity onset diabetes of the young; HNF1A, hepatocyte nuclear factor 1-alpha; HNF4A, hepatocyte nuclear factor 4-alpha; GCK, glucokinase; PAD, peroral antidiabetic drugsNovel mutation; HNF1A; GCK; MODY

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia

Keywords: ASK1; apoptosis-sensitive kinase; MAPK; mitogen-activated protein kinase; MAPKK/MKK; MAPK kinase; MAPKKK; MAPKK kinase; JNK; c-Jun N-terminal kinase; ERK; extracellularly regulated kinase; SAPK; stress-activated protein kinase; MEKK; MAPK/ERK kinase; MLK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA1, p42 and p38α

Keywords: LPA; lysophosphatidic acid; MAPK; mitogen-activated protein kinases; siRNA; small interfering RNA; PTX; pertussis toxin; PD; PD98059; SB; SB203580; U0; U0126; ERK; extracellular signal-regulated kinase; JNK; c-Jun/N terminal kinases; IGF; insulin-like gro

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis

Keywords: NIK; Nck-interacting kinase; NESK; NIK-like embryo-specific kinase; GCK; Germinal center kinase; JNK; c-Jun N-terminal kinase; TNF-α; Tumor necrosis factor-α; CNH; Citron and NIK homology; GFP; Green fluorescence protein; CHX; Cycloheximide; PARP; Poly

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Contemporary strategies in the diagnosis and management of neonatal hyperinsulinaemic hypoglycaemia

Keywords: Hyperinsulinism; Hypoglycaemia; β-cell; ABCC8; KCNJ11; GLUD1; GCK; HADHSC;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه