Keywords: Thioredoxins; Cholestasis; Oxidative stress; Cholangiocyte; ALT; Alanine aminotransferase; BDL; Bile duct ligation; GCLC; Gamma-glutamylcysteine; GSH; Reduced glutathione; GST; Glutathione S-Transferase; HO-1; Heme Oxygenase 1; 4-HNE; 4-hydroxy-2-nonenal;
مقالات ISI (ترجمه نشده)
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Keywords: Methylmercury; GCLC; GCLM; GSTP1; Neurodevelopment;
Keywords: AST; aspartate aminotransferase; ALT; alanine aminotransferase; CBS; cystathionine β-synthase; DNMT; DNA methyltransferase; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; glutathione; LPO; lipid
Keywords: Arsenite; Mitochondrial superoxide; Nrf2, GSH; Mitochondrial permeability transition; Apoptosis; AA; l-ascorbic acid; BSO; DL-buthionine-[S,R]-sulfoximine; CsA; cyclosporin A; DHR; dihydrorhodamine 123; DTNB; dithiobis-(2-nitrobenzoic acid); EB; extracell
Keywords: ACR; albumincreatinine ratio; ALT; alanine aminotransferase; AST; aspartic transaminase; BUN; blood urea nitrogen; BW; body weight; CAT; catalase; CK; creatine kinase; Col1α1; collagen1α1; CREA; creatinine; GCLC; glutamate-cysteine ligase catalytic subu
Keywords: nPM / PM0.2; Nano-Scale Particulate Matter / Particulate Matter <â¯0.2â¯Âµm diameter; PM2.5; Particulate Matter <â¯2.5â¯Âµm diameter; Nrf2; Nuclear factor (erythroid-derived 2)-like 2; Bach1; BTB Domain And CNC Homolog 1; c-Myc; MYC proto-oncogene; TR
Keywords: 18S; 18S ribosomal RNA; 36B4; acidic ribosomal protein 36B4; Acc1; acetyl-CoA carboxylase α; Acox1; acyl-CoA oxidase 1; Apob; apolipoprotein B; ARE; antioxidant response element; AST; aspartate aminotransferase; ALT; alanine aminotransferase; ATF4; activ
Keywords: Glutathione; Hemolytic anemia; GCLC; Glutamate-cysteine ligase; Gamma-glutamylcysteine synthetase;
Keywords: Propolis; Fibroblast; Wound healing; Antioxidant activity; EECP; Ethanol extract of Chinese propolis; HPLC; High performance liquid chromatography; H2O2; Hydrogen peroxide; HO-1; Heme oxygenase-1; GCLC; Glutathione-cysteine ligase catalytic subunits; GCLM
Effect of metabolites of hydroxytyrosol on protection against oxidative stress and inflammation in human endothelial cells
Keywords: AUC; area-under-the-curve; CCL2; chemokine (CC) motif ligand 2; DAPI; diamino-fenilindol; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic subunit; GPx1; glutathione peroxidase 1; GSH; glutathione; hECs; human end
Comparison of chemical structures and cytoprotection abilities between direct and indirect antioxidants
Keywords: AAPH; 2,2â²-azobis (2-amidinopropane) dihydrochloride; ARE; antioxidant responsive element; CAT; catalase; DHMBA; 3,5-dihydroxy-4-methoxybenzyl alcohol; DPPH; 2,2-diphenyl-1-picryl-hydrazyl; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehy
Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy
Keywords: Glutathione; Magnetic resonance spectroscopy; Brain; Glyoxalase; Psychiatric disease; Neurological disease; GSH; glutathione; GSSG; oxidized glutathione; NMDA; N-methyl-D-aspartate; GCL; glutamate-cysteine ligase; GCLC; glutamate-cysteine ligase subunit w
Keywords: DTC; dithiocarbamates; EGCG; (-)-epigallocatechin-3-gallate; DSF; disulfiram; DEDTC; diethyldithiocarbamate; PDTC; pyrrolidine dithiocarbamate; SOD; superoxide dismutase; MT; metallothionein; ROS; reactive oxygen species; γH2AX; histone H2AX; ALT; alanin
Keywords: transporters; metabolism; drug-metabolizing enzymes; pharmacokinetics; hepatic transport; hepatic metabolism; organic anion-transporting polypeptide transporters; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATP; adenosine triphosphate;
Keywords: Cardiorenal syndrome; Naringenin; Oxidative stress; Nrf2; GCLc
Keywords: Q3G; quercetin 3-O-β-glucoside; Q4â²G; quercetin 4â²-O-β-glucoside; OPAC; 3-hydroxyphenylacetic acid; DOPAC; 3,4-dihydroxyphenylacetic acid; PCA; protocatechuic acid (3,4-dihydroxybenzoic acid); HPA; hippuric acid; DPPH; 1,1-diphenyl-2-picrylhydrazyl;
Keywords: Sirt1; Sirtuin 1; DMN; dimethylnitrosamine; HO-1; Heme oxygenase -1; GST; glutathione-S-transferase; GCLC; glutathione cysteine ligase catalytic subunit; GCLM; glutathione cysteine ligase modifier subunit; Nrf2; NF-E2-related factor 2; ALT; alanine aminot
Keywords: AgNP; silver nanoparticles; PBS; phosphate buffered saline; DMSO; dimethyl sulfide; EPR; electron paramagnetic resonance; FACS; fluorescence activated cell sorting; FCS; fetal calf serum; GCLC; glutamate-cysteine ligase catalytic subunit; GSH; reduced glu
Keywords: Agmatine; Antidepressants; Central nervous system; Depression; Neuroprotection; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ARE; antioxidant response element; BDNF; brain-derived-neurotrophic factor; BBB; blood-brain barrier; CRE; cAMP
Keywords: HF; high-fat; CO; control; PCOOH; phosphatidylcholine hydroperoxide; Gpx1; glutathione peroxidase 1; Sod1; superoxide dismutase 1; Gpx4; glutathione peroxidase 4; Cat; catalase; Gclm; glutamate-cysteine ligase modifier subunit; PC; phosphatidylcholine; CL
Keywords: PAPS; 3â²-Phosphoadenosine 5â²-phosphosulfate; DTNB; 5,5â²-Dithiobis(2-nitrobenzoic acid); APAP; Acetaminophen; ALT; Alanine aminotrasferase; BSA; Bovine serum albumin; CCl4; Carbon tetrachloride; Ccr2; C-C chemokine receptor 2; CFB; Clofibrate; CD;
Keywords: Acat2; cholesterolacyl transferase 2; ALT; alanine aminotransferase; AST; aspartate aminotransferase; Bax; Bcl-2-associated x protein; BUN; blood urea nitrogen; CREA; creatinine; DBIL; direct bilirubin; DMEM; Dulbecco's modified eagle medium; Gclc; glut
Keywords: Antioxidant; Oxidative stress; Redox; Tumor; Cancer therapy; Akt; protein kinase B; AMPK; 5â²-adenosine monophosphate-activated protein kinase; ATM; ataxia telangiectasia-mutated; DR5; death receptor 5; EC; epicatechin; ECG; epicatechin-3-gallate; EGC; e
Keywords: HHcy; hyperhomocysteinemia; ZDF; Zucker diabetic fatty; CβS; cystathionine β-synthase; BHMT; betaine-homocysteine methyltransferase; SAM; S-adenosylmethionine; SAH; S-adenosylhomocysteine; MS; methionine synthase; GSH; glutathione; CDO; cysteine dioxyge
Keywords: AJ; adherens junction; BBB; blood-brain barrier; DMF; dimethyl fumarate; FAE; fumaric acid esters; Gclc; glutamate-cysteine ligase catalytic subunit; Gclm; glutamate-cysteine ligase modifier subunit; HO-1; heme oxygenase-1; Keap-1; kelch-like erythroid
Keywords: ARE; Antioxidant responsive element; Cul3; Cullin 3; DEVD; Asp-Glu-Val-Asp; DOX; Doxorubicin; GCLC; Catalytic subunit of glutamate-cysteine ligase; GCLM; Modified subunit of glutamate-cysteine ligase; GSTA4-4; Glutathione S-transferase alpha 4;
Keywords: AD; Alzheimer disease; AIF; apoptosis-inducing factor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic subunit; GSH; reduced glutathione; GSSG; oxidized glutathione; GR; glutathione reductase; GS; glutathione s
Keywords: Antioxidant gene therapy; Brain ischemia; Neurodegenerative disorders; Oxidative stress; Virus-mediated gene delivery; ROS; ÎΨm; mitochondrial membrane potential; 3-NP; 3-nitropropionic acid; 6-OHDA; 6-hydroxydopamine; AADC; aromatic-l-amino decarboxyla
Keywords: ARE; antioxidant response element; CBP; CREB-binding protein; ChIP; chromatin immunoprecipitation; co-IP; coimmunoprecipitation; GCL; glutamate-cysteine ligase; Gclc; GCL catalytic subunit; Gclm; GCL modifier subunit; GSH; reduced glutathione; GS; GSH s
Keywords: COPD; chronic obstructive pulmonary disease; FEV1; forced expiratory volume in the first second; FVC; forced vital capacity; GCLC; glutamate-cysteine ligase (catalytic subunit); GGT2; γ-glutamyl transferase 2; GLRX; glutaredoxin; GST; glutathione S-tra
Keywords: 4-HNE; 4-hydroxynonenal; 15d-PGJ2; 15-deoxy-â12,14-prostaglandin J2; AP-1; activator protein-1; As3 +; trivalent arsenite; α-SMA; a-smooth muscle actin; ARE; antioxidant response element; ATRA; all-trans retinoic acid; BDL; bile duct ligation; BHMT; b
Keywords: ROS; reactive oxygen species; GSH; reduced glutathione; Gcl; glutamate-cysteine ligase; Gclc; glutamate-cysteine ligase catalytic subunit; Gclm; glutamate-cysteine ligase modifier subunit; Gss; glutathione synthetase; GSSG; glutathione disulfide; PC
Activation of Nrf2 pathway and inhibition of NLRP3 inflammasome activation contribute to the protective effect of chlorogenic acid on acute liver injury
Keywords: ALT; alanine transaminase; ASC; apoptosis-associated speck-like protein; AST; aspartate transaminase; AREs; antioxidant response elements; CAT; catalase; CGA; chlorogenic acid; CCl4; carbon tetrachloride; CYP2E1; cytochrome P450 2E1; GCLC; glutamate-cyste
4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells
Keywords: Chemoprevention; Isothiocyanate; 4-Methylthio-3-butenyl isothiocyanate; Nuclear factor (erythroid-derived 2)-like 2; Reactive oxygen species; AITC; allyl isothocyanate; AP-1; activator protein-1; BITC; butyl isothiocyanate; ERK; extracellular signal-regul
Comparative effects of cadmium, zinc, arsenic and chromium on olfactory-mediated neurobehavior and gene expression in larval zebrafish (Danio rerio)
Keywords: Nrf2; nuclear factor, erythroid 2-like 2; omp; olfactory marker protein b; dpf; days post fertilization; EM; E3 embryo medium; SRP; Superfund Research Program; Zn; zinc; As; arsenic; Cr; chromium; Cd; cadmium; TCA; taurocholic acid; OE; olfactory epitheli
Age-dependent regulation of antioxidant genes by p38α MAPK in the liver
Keywords: Akt; Protein kinase B; AP-1; Activator protein-1; ASK1; Apoptosis signal-regulating kinase 1; ATF2; activating transcription factor 2;; ChIP; Chromatin immunoprecipitation;; DEN; Diethyl nitrosamine;; EGFR; Epidermal growth factor receptor; G6PDH; Glucose
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway
Keywords: ALI; acute liver injury; AST; aspartate transaminase; CD14; cluster of differentiation 14; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; glutamate-cysteine ligase modifier subunit; GSH; reduced glutathione; HO-1; hemeoxygenase-1; iNOS; inducibl
Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes
Keywords: Acadm; medium-chain acyl-CoA dehydrogenase; AMPKα; AMP-activated protein kinase, α subunit; AST; aspartate aminotransferase; ALT; alanine aminotransferase; BSO; buthionine sulfoximine; CBS; cystathionine-β-synthetase; CPT1a; carnitine palmitoyltransfer
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro
Keywords: Nuclear factor erythroid-2-related factor 2 (Nrf2); Acetaminophen (APAP); Acute liver injury; Oxidative stress; Ginsenoside Rg1; ALT; alanine transaminase; ARE; antioxidant element; AST; aspartate transaminase; CAT; catalase; GCL; glutamate-cysteine ligas
Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription
Keywords: ARE; antioxidant response element; CaMKII; Ca2+/calmodulin-dependent kinase II; GCLC; glutamate-cysteine ligase; GR; glutathione reductase; GSH; reduced glutathione; GSSG; oxidized glutathione; IκK; inhibitor of nuclear factor kappa-B kinase; Keap-1; Kel
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
Keywords: AKR; aldo-keto reductase; ARE; antioxidant response element; CD44; cluster of differentiation 44; CSC; cancer stem cell; GCLC; glutamate-cysteine ligase catalytic subunit; GPX; glutathione peroxidase; GSH; glutathione; HO-1; heme oxygenase-1; HA; hyaluron
Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats
Keywords: ARE/EpRE; antioxidant/electrophile response element; BrdU; bromodeoxyuridine; CA; cinnamic aldehyde; CVD; cardiovascular disease; DHE; dihydroethidium; DM; diabetes mellitus; GCLC; glutamate-cysteine ligase catalytic subunit; GSH; glutathione; HO-1; heme
Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway
Keywords: ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;
Centella asiatica attenuates hippocampal mitochondrial dysfunction and improves memory and executive function in β-amyloid overexpressing mice
Keywords: AD; Alzheimer's Disease; ADP; Adenosine diphosphate; Aβ; β-amyloid; CAW; Water extract of Centella asiatica; CFR; Conditioned fear response; ETC; Electron transport chain; FCCP; Carbonyl cyanide p-(trifluoromethoxy)phenylhydrazone; GAPDH; Glyceraldehyde
Cardioprotective role of azafrin in against myocardial injury in rats via activation of the Nrf2-ARE pathway
Keywords: Myocardial infarction; Ischaemia-reperfusion injury; Nrf2-ARE pathway; Azafrin; Oxidative stress; ARE; antioxidant response element; AST; aspartate aminotransferase; CK-MB; MB isoenzyme of creatine kinase; cTnI; cardiac troponin I; CVD; cardiovascular dis
Inhibition of NRF2 signaling and increased reactive oxygen species during embryogenesis in a rat model of retinoic acid-induced neural tube defects
Keywords: Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; HO-1; heme oxygenase-1; NQO1; NADP(H): quinine oxidoreductase 1; GSTs; glutathione S-transferases; TXNRD; thioredoxin reducta
Anti-inflammatory activity of the decoction of Forsythia suspensa (Thunb.) Vahl is related to Nrf2 and A20
Keywords: WFF; the water extract of Forsythiae Fructus; TNFAP3 A20; tumor necrosis factor α-induced protein 3; HPLC; high-performance liquid chromatography; ROS; reactive oxygen species; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FACS; Flu
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway
Keywords: ARE; antioxidant response element; Bcl-2; B-cell lymphoma 2; CA; caffeic acid; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic subunit; GCLM; gl
Nrf2 inhibits oxaliplatin-induced peripheral neuropathy via protection of mitochondrial function
Keywords: AOPPs; advanced oxidation protein products; CI; cell index; DCFH-DA; 2â²,7â²-Dichlorofluorescin diacetate; DHE; dihydroethidium; DAB; 3,3â²-diaminobenzidine-tetrahydrochloride-dihydrate; DRG; dorsal root ganglion; GCLC; glutamate-cysteine ligase cataly
Marliolide inhibits skin carcinogenesis by activating NRF2/ARE to induce heme oxygenase-1
Keywords: HO-1; Heme oxygenase-1; NRF2; NF-E2-related factor 2; KEAP1; Kelch-like ECH-Associated protein 1; ARE; Antioxidant response element; GCLC; glutamate-cysteine ligase modifier catalytic unit; MEF; Mouse embryonic fibroblast; DMBA; 12-Dimethylbenz[a]anthrace