دانلود مقالات ISI درباره Gcn5 + ترجمه فارسی

ابزارهای اپیزیونیک (نویسندگان، خوانندگان و پاک کننده ها) و پیامدهای آنها در درمان سرطان

Epigenetic tools (The Writers, The Readers and The Erasers) and their implications in cancer therapy

Keywords: ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی اثربخشی و ریسک درمانهای ضد دیابتی: تجویز داروهای سنتی - تجدیدنظر مکانیکی برای درک نحوه عملکرد آنها

Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs-A mechanistic revisit to understand their mode of action

Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

سنتز یک سری جدید از مهار کننده های هیستون استیل ترانسفراز مبتنی بر تیازول

Synthesis of a novel series of thiazole-based histone acetyltransferase inhibitors

Keywords: Histone acetyltransferase; Inhibitor; Acetylation; Thiazole; Gcn5; p300;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

تغییرات اپیگنتیک توسط فیتوشیمیایی جیره: پیامدهای تغذیه فردی

Epigenetic modifications by dietary phytochemicals: Implications for personalized nutrition

Keywords: Epigenetics; Phytochemicals; DNA-methylation; Histone-modification; miRNA; Carcinogenesis; Akt; v-akt murine thymoma viral oncogene homolog 1; AP-1; Activator Protein-1; Bax; BCL2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; Bcl-xL; B-cell lymphoma-

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2013 سفارش ترجمه

Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration

Keywords: HAT; histone-acetyltransferase; Gcn5; General Control Nonderepressible; HDAC; histone deacetylase; CPTH2; cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone; Ubp8; ubiquitin protease 8; DUB; deubiquitylation; Psh1; E3-ubiquitin ligase; Ub; ubiq

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of 1,8-acridinedione derivatives as novel GCN5 inhibitors via high throughput screening

Keywords: Epigenetics; Histone acetyltransferase; GCN5; High throughput screening; 1,8-Acridinedione derivative;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

SIRT6 expression and oxidative DNA damage in individuals with prediabetes and type 2 diabetes mellitus

Keywords: 8-OHdG; 8-hydroxy deoxyguanosine; ACE; angiotensin converting enzyme; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ELISA; enzyme-linked immunosorbent assay; GCN5; General Control Non-repressed Protein 5; GGT;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Cross-pathway control gene CPC1/GCN4 coordinates with histone acetyltransferase GCN5 to regulate catalase-3 expression under oxidative stress in Neurospora crassa

Keywords: CAT; catalase; H2O2; hydrogen peroxide; ROS; reactive oxygen species; HAT; histone acetyltransferase; GCN5; general control nonderepressible-5; CPC1; cross pathway control-1; ChIP; chromatin immunoprecipitation assay; GCN5; CPC1/GCN4; Histone acetylation;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Insulin-induced inhibition of gluconeogenesis genes, including glutamic pyruvic transaminase 2, is associated with reduced histone acetylation in a human liver cell line

Keywords: ChIP; chromatin immunoprecipitation; FOXO1; forkhead box protein O1; GCN5; general control of amino acid synthesis 5; G6PC; glucose-6-phosphatase; GGT; γ-glutamyltransferase; GOT; glutamic-oxaloacetic transaminase; GPT; glutamic pyruvic transaminase; P

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation

Keywords: Acetylation; GCN5; Mitochondria; SIRT1; Deacetylase; PGC-1α; AMP; adenosine monophosphate; Ca2+; calcium; CBP; CREB-binding protein; Cre-MCK; creatine kinase promoter; CHO; carbohydrate; DAC; deacetylase; ETC; electron transport chain; ExT; endurance exe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases

Keywords: ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Supt20 is required for development of the axial skeleton

Keywords: Supt20; Gcn5; Somitogenesis; Somite patterning; Hox code;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum

Keywords: Plasmodium falciparum; Virtual screening; Epigenetics; HAT; GCN5;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

SAGA complex and Gcn5 are necessary for respiration in budding yeast

Keywords: KAT; K-acetyltransferase; Gcn5; General Control Nonderepressible; HDAC; histone deacetylase; CPTH2; cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone; SAGA; Spt,Ada, Gcn5-acetyltransferase complex, SLIK SAGA-like complex; SAGA complex; Gcn5; H

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of GCN5 remarkably enhances the resistance against prolonged endoplasmic reticulum stress-induced apoptosis through up-regulation of Bcl-2 gene expression

Keywords: Apoptosis; Bcl-2; ER stress; GCN5; Gene targeting; AFT4; activating transcription factor 4; AFT6; activating transcription factor 6; Bax; B-cell lymphoma-associated X; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra-large; CHOP; C/EBP-homologous p

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

SWI/SNF recruitment to a DNA double-strand break by the NuA4 and Gcn5 histone acetyltransferases

Keywords: Chromatin; Homologous recombination; SWI/SNF; Gcn5; NuA4; Histone acetyltransferase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Function and subcellular localization of Gcn5, a histone acetyltransferase in Candida albicans

Keywords: Gcn5; Histone acetyltransferase; Hyphal elongation; Subcellular localization; Candida albicans;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

A2b adenosine signaling represses CIITA transcription via an epigenetic mechanism in vascular smooth muscle cells

Keywords: CIITA; class II transactivator; GCN5; general control of amino acid synthesis protein 5; PCAF; p300-and-CBP-associated factor; STAT1; signal transducer and activator of transcription 1; VSMC; vascular smooth muscle cell; WDR5; WD repeat-containing protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Protein kinase Cθ gene expression is oppositely regulated by GCN5 and EBF1 in immature B cells

Keywords: 5′-RACE; 5′-rapid amplification of cDNA ends; BCR; B cell receptor; ChIP; chromatin immunoprecipitation; EBF1; early B cell factor 1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; H3K14; Lys-14 of histone H3; H3K9; Lys-9 of histone H3; HAT; histone

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Acetylation of cyclin-dependent kinase 5 is mediated by GCN5

Keywords: CDK5; GCN5; Acetylation; K33; ATP;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis

Keywords: Akt/PKB; acutely transforming retrovirus AKT8 in rodent T cell lymphoma/protein kinase B; AMPK; AMP-activated protein kinase; CBP; CREB-binding protein; C/EBP; CCAAT enhancer binding protein; CNS; central nervous system; CREB; cAMP-responsive binding prot

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

Keywords: 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2012 سفارش ترجمه

Regions of intrinsic disorder help identify a novel nuclear localization signal in Toxoplasma gondii histone acetyltransferase TgGCN5-B

Keywords: Apicomplexa; Parasite; Cellular trafficking; GCN5; Chromatin; Epigenetics;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

GCN5 regulates the activation of PI3K/Akt survival pathway in B cells exposed to oxidative stress via controlling gene expressions of Syk and Btk

Keywords: AKT; acutely transforming retrovirus AKT8 in rodent T cell lymphoma; BCR; B cell receptor; Btk; Bruton's tyrosine kinase; ChIP; chromatin immunoprecipitation; GCN5; general control non-depressible 5; H2O2; hydrogen peroxide; HAT; histone acetyltransfera

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Knock down of GCN5 histone acetyltransferase by siRNA decreases ethanol-induced histone acetylation and affects differential expression of genes in human hepatoma cells

Keywords: Epigenetics; Ethanol; GCN5; Human hepatoma cells; Histone acetylation; Histone acetyltransferase

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

An electrophoretic mobility shift assay for the identification and kinetic analysis of acetyl transferase inhibitors

Keywords: Electrophoretic mobility shift assay; Acetyl transferase; GCN5

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Nutrient-dependent regulation of PGC-1α's acetylation state and metabolic function through the enzymatic activities of Sirt1/GCN5

Keywords: PGC-1α; GCN5; Sirt1; Acetylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Complex assembly on the human CYP17 promoter

Keywords: CYP17; p54nrb; GCN5; SRC-1; cAMP; Steroidogenic factor-1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Functional connection between histone acetyltransferase Gcn5p and methyltransferase Hmt1p

Keywords: Histone; Acetylation; Methylation; GCN5; HMT1; RMT1; Saccharomyces cerevisiae;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Characterization of a phosphatase 2C protein as an interacting partner of the histone acetyltransferase GCN5 in Arabidopsis

Keywords: Plant chromatin modification; Histone acetylation; HAT; GCN5; PP2C

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Control of transcription in Schistosoma mansoni: Chromatin remodeling and other regulatory elements

Keywords: Schistosoma mansoni; Chromatin; HMGB1; GCN5; Methylation; Acetylation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Gcn5p contributes to the bidirectional character of the UGA3–GLT1 yeast promoter

Keywords: Bidirectional promoters; Chromatin organization; GCN5; UGA3; GLT1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Decoding Tat: the biology of HIV Tat posttranslational modifications

Keywords: HIV; Tat; Posttranslational modification; CDK9; cyclin-dependent kinase 9; GCN5; general control of amino acid synthesis 5; NAD+; nicotinamide adenine dinucleotide; nuc-1; nucleosome 1 located immediately downstream of the start of transcription at the HI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Intimate relationship between the genes of two transcriptional coactivators, ADA2a and PIMT, of Drosophila

Keywords: ADA; alteration/deficiency in activation; CBP/p300; cAMP-response element-binding protein binding protein; CN; central nervous; CTD; carboxyl terminal domain; DPE; downstream promoter element; DRE; DNA replication-related element; DREF; DRE binding factor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Smads and chromatin modulation

Keywords: AER; apical ectodermal ridge; ACF; ATP-utilizing chromatin assembly and remodeling factor; AML; acute myeloid leukaemia; AMT; arginine methyl transferase; ARC; activator-recruited cofactor; BAF; BRG1/hBRM-associated factors; BMP; bone morphogenic protein;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2005 سفارش ترجمه