Keywords: ژنوتوکسیک; Carcinogenesis; Chemicals; Genotoxic; Risk assessment;
مقالات ISI ژنوتوکسیک (ترجمه نشده)
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Keywords: ژنوتوکسیک; Electromagnetic field; Frequency; Carcinogenic; Genotoxic;
Keywords: ژنوتوکسیک; Imatinib mesylate; Cytotoxic; Genotoxic; Zebrafish liver cells; HepG2 cells; Human peripheral blood lymphocytes;
Keywords: ژنوتوکسیک; Acridinium-ester; Chemiluminescence; Genotoxic; Cystatin A (CSTA); RAD51C; Tumour suppressor p53 (TP53);
Keywords: ژنوتوکسیک; Estrogen; Metabolites; Genotoxic; Breast cancer; Aromatase; Adducts;
Keywords: ژنوتوکسیک; Biomass burning; Brazilian Amazon; Micronuclei; Genotoxic; Organic particulate matter;
Keywords: ژنوتوکسیک; Microalgae; Fermentation; Oleic-rich oil; Genotoxic; Mutagenic; Subchronic toxicity; 2-AA; 2-aminoanthracene; AAALAC; Association for Assessment and Accreditation of Laboratory Animal Care International; ANOVA; Analysis of Variance; AOAC; Association of A
Genotoxicity and cytotoxicity of three microcystin-LR containing cyanobacterial samples from Antioquia, Colombia
Keywords: ژنوتوکسیک; Cyanobacteria; Microcystins; Genotoxic; Comet assay; Damage level;
Genotoxicity and physiological effects of CeO2 NPs on a freshwater bivalve (Corbicula fluminea)
Keywords: ژنوتوکسیک; Cerium dioxide nanoparticles (CeO2 NPs); Biomarker; Comet assay; Genotoxic; Apoptosis; Corbicula fluminea;
Antigenotoxic, antimutagenic and cytoprotective potential of Salvia hispanica L. seed extract on human leukocytes exposed to oxidative damage
Keywords: ژنوتوکسیک; Genotoxic; Mutagenic; Chia; Salvia hispanica; Cell culture;
Evaluation the urban atmospheric conditions in different cities using comet and micronuclei assay in Tradescantia pallida
Keywords: ژنوتوکسیک; Air pollution; Bioassay; Biomonitoring; Genetic damage; Genotoxic; Mutagenesis;
Evaluation of in vivo and in vitro toxicological and genotoxic potential of aluminum chloride
Keywords: ژنوتوکسیک; Aluminum; Cytotoxicity; Genotoxic; Micronucleus test; Risk assessment; Swiss mice;
In vivo genotoxicity evaluation of efavirenz (EFV) and tenofovir disoproxil fumarate (TDF) alone and in their clinical combinations in Drosophila melanogaster
Keywords: ژنوتوکسیک; Antiretrovirals; Genotoxic; Mutagenic; Recombinogenic;
Research articleExploration of acute genotoxic effects and antigenotoxic potential of gambogic acid using Allium cepa assay
Keywords: ژنوتوکسیک; Gambogic acid; Root tip; Genotoxic; Clastogenic;
Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines
Keywords: ژنوتوکسیک; Naringenin; Naringenin-oxime; Cytotoxic; Genotoxic; Apoptosis; Reactive oxygen species; Comet assay;
Inhibition of Bcl-2 or IAP proteins does not provoke mutations in surviving cells
Keywords: ژنوتوکسیک; Bcl-2; IAP; DNA damage; Genotoxic; Late effects; Second malignant neoplasms
Assessment of toxicity and genotoxicity of low doses of 5-fluorouracil in zebrafish (Danio rerio) two-generation study
Keywords: ژنوتوکسیک; Anticancer drugs; 5-Fluorouracil; Chronic exposure; Danio rerio; Genotoxic; Toxicogenomic
Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-d-ribose 2â²-oxidase
Keywords: ژنوتوکسیک; TB; tuberculosis; Mtb; Mycobacterium tuberculosis; MIC; minimal inhibitory concentration; CYP; cytochrome P450; SAR; structure-activity relationships; MMIC; mammalian cytotoxicity; DprE1; decaprenylphosphoryl-β-d-ribose 2â²-oxidase; TEA; triethylamine
Cytotoxic and genotoxic properties of leaf extract of Icacina trichantha Oliv.
Keywords: ژنوتوکسیک; Cytotoxic; Genotoxic; Icacina trichantha; Leaf; Allium cepa assay;
Human health risk assessment of nitrosamines and nitramines for potential application in CO2 capture
Keywords: ژنوتوکسیک; CO2 capture; Risk assessment; Nitrosamines; Nitramines; Carcinogenic; Genotoxic; Non-threshold substances; Extrapolation modeling; T25; DMEL;
Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?
Keywords: ژنوتوکسیک; NNK; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; 2NF; 2-nitrofluorene; MTT test; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test; TPA; 12-O-tetradecanoylphorbol-13-acetate; AFB1; Aflatoxin B1; BaP; benzo(a)pyrene; CA; chromosome aber
Degradation of Rabeprazole-N-oxide in aqueous solution using sonication as an advanced oxidation process
Keywords: ژنوتوکسیک; Genotoxic; Pharmaceutical; Ultrasonication; Persistent; Cavitation
Evaluation of N-acetyl-cysteine against tetrachlorobenzoquinone-induced genotoxicity and oxidative stress in HepG2 cells
Keywords: ژنوتوکسیک; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; ELISA; enzyme-linked immunosorbent assay; γ-H2AX; phosphorylation of histone H2AX; MN; micronucleus; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-dip
Antimicrobial, antioxidant, mutagenic and antimutagenic activities of Distephanus angulifolius and Ormocarpum trichocarpum
Keywords: ژنوتوکسیک; Ames test; Antibacterial; Genotoxic; DPPH; Medicinal plants;
Evaluation of cytotoxic effects of atrazine and glyphosate herbicides on Biomphalaria glabrata snails
Keywords: ژنوتوکسیک; Genotoxic; Biomphalaria glabrata; Atrazine and glyphosate; Protein profiles; RAPD-PCR; Isozymes
Serum complement enhances the responses of genotoxin- and oxidative stress-sensitive Escherichia coli bioreporters
Keywords: ژنوتوکسیک; Bioluminescence; Genotoxic; Oxidative stress; Serum; Complement
Waterborne cadmium impacts immunocytotoxic and cytogenotoxic endpoints in green-lipped mussel, Perna canaliculus
Keywords: ژنوتوکسیک; Genotoxic; Immune system; Haemocytes; Gill; Micronucleus test; Comet assay
Evidence of DNA damage in humans inhabiting a volcanically active environment: A useful tool for biomonitoring
Keywords: ژنوتوکسیک; MNC; micronucleated cells; ONA; cells with other nuclear anomalies; Buccal exfoliated cells; Micronuclei; Genotoxic; Volcanism;
In vitro genotoxicity evaluation of acetamiprid in CaCo-2 cells using the micronucleus, comet and γH2AX foci assays
Keywords: ژنوتوکسیک; Acetamiprid; Genotoxic; CaCo-2; Comet; Micronucleus; γH2AX
A validated CE method for determining dimethylsulfate a carcinogen and chloroacetyl chloride a potential genotoxin at trace levels in drug substances
Keywords: ژنوتوکسیک; Dimethyl sulfate; Chloroacetyl chloride; Genotoxic; Capillary electrophoresis and validation
Testing the cytotoxicity and genotoxicity of the antimalarial drug mefloquine
Keywords: ژنوتوکسیک; Mefloquine (MQ); Cytotoxic; Genotoxic; Spermatocyte diakinesis metaphase-1
Guidelines and pharmacopoeial standards for pharmaceutical impurities: Overview and critical assessment
Keywords: ژنوتوکسیک; Impurities; Toxicology; Genotoxic; TTC; Drug safety; Risk assessment; Analysis; Pharmacopoeia; ICH; Guideline; Qualification;
In vivo genotoxicity evaluation of atrazine and atrazine-based herbicide on fish Carassius auratus using the micronucleus test and the comet assay
Keywords: ژنوتوکسیک; Aquatic; Genotoxic; Fish; Atrazine; Micronucleus test; Comet assay;
Using estimates of metal bioavailability in the soil and genetic variation of allozymes to investigate heavy metal tolerance in the earthworm Eisenia fetida (Oligochaeta)
Keywords: ژنوتوکسیک; Resistance; Cadmium; Metal; Eisenia fetida; Genotoxic
Assessing the genotoxic potentials of arsenic in tilapia (Oreochromis mossambicus) using alkaline comet assay and micronucleus test
Keywords: ژنوتوکسیک; Arsenic; Oreochromis mossambicus; Genotoxic; Micronucleus; Alkaline comet assay; DNA damage;
Improved in silico prediction of carcinogenic potency (TD50) and the risk specific dose (RSD) adjusted Threshold of Toxicological Concern (TTC) for genotoxic chemicals and pharmaceutical impurities
Keywords: ژنوتوکسیک; TTC; Threshold of toxicological concern; Genotoxic; Mutagenic; Impurities; QSAR; SAR; TD50; Pharmaceuticals; Food contact substances; RSD; Carcinogenicity;
Control and analysis of hydrazine, hydrazides and hydrazones—Genotoxic impurities in active pharmaceutical ingredients (APIs) and drug products
Keywords: ژنوتوکسیک; Hydrazine; Genotoxic; Derivatisation; Chromatography; Spectroscopy
In silico approaches to predicting cancer potency for risk assessment of genotoxic impurities in drug substances
Keywords: ژنوتوکسیک; Genotoxic; Impurities; In silico; Carcinogenicity; Threshold of toxicological concern; Pharmaceutical; TD50; Cancer potency;
Risk assessment of consumption of methylchavicol and tarragon: The genotoxic potential in vivo and in vitro
Keywords: ژنوتوکسیک; Tarragon; Methylchavicol; Estragole; Genotoxic; Risk assessment
Analytical approaches for the detection of epoxides and hydroperoxides in active pharmaceutical ingredients, drug products and herbals
Keywords: ژنوتوکسیک; Epoxide; Hydroperoxide; Genotoxic; Herbal; Chromatography
Risk assessment of carcinogens in food
Keywords: ژنوتوکسیک; Risk assessment; Carcinogen; Genotoxic; Non-genotoxic; Food
Application of the Margin of Exposure (MOE) approach to substances in food that are genotoxic and carcinogenic
Keywords: ژنوتوکسیک; Margin of Exposure; MoE; Genotoxic; Carcinogens; Modelling; Exposure
Non-linear dose–response of DNA-reactive genotoxins: Recommendations for data analysis
Keywords: ژنوتوکسیک; Dose–response; DNA reactive; EMS; Genotoxic; MMS; Threshold
Induction of micronuclei and sister chromatid exchange in bone-marrow cells and abnormalities in sperm of Algerian mice (Mus spretus) exposed to cadmium, lead and zinc
Keywords: ژنوتوکسیک; Cadmium; Lead; Zinc; Genotoxic; Micronucleus; Sister chromatid exchange; Sperm abnormalities
Assessment of genotoxic and mutagenic effects of chlorpyrifos in freshwater fish Channa punctatus (Bloch) using micronucleus assay and alkaline single-cell gel electrophoresis
Keywords: ژنوتوکسیک; DNA damage; Chlorpyrifos; Comet assay; Micronucleus assay; Genotoxic; Channa punctatus
Combination of in vitro bioassays for the determination of cytotoxic and genotoxic potential of wastewater, surface water and drinking water samples
Keywords: ژنوتوکسیک; Salmonella typhimurium TA1535/pSK1002; HepG2; Surface waters; Wastewaters; Genotoxic; Cytotoxic
A comparison of concentrations of polycyclic aromatic compounds detected in dust samples from various regions of the world
Keywords: ژنوتوکسیک; Polycyclic aromatic hydrocarbons; House dust; Genotoxic; Cancer; Environmental health
Quantifiable mRNA transcripts for tamoxifen-metabolising enzymes in human endometrium
Keywords: ژنوتوکسیک; CYP3A4; Endometrial carcinoma; Genotoxic; Selective oestrogen receptor modulator; SULT2A1; Tamoxifen;
Risk assessment of dietary exposures to compounds that are genotoxic and carcinogenic—An overview
Keywords: ژنوتوکسیک; Risk assessment; Dietary exposure; Genotoxic; Carcinogenic
Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance
Keywords: ژنوتوکسیک; Genotoxic; Impurities; Mixtures; Drug substance