Keywords: گیرنده پپتید-1 مانند گلوکاگون; aPKC; atypical protein kinase C; CBP; CREB binding protein; ChREBP; carbohydrate response element-binding protein; CREB; cAMP response element-binding protein; CRTC2; CREB-regulated transcription coactivator 2; FA; fatty acid; GIPR; glucose-dependent insu
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Keywords: گیرنده پپتید-1 مانند گلوکاگون; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CHO; Chinese hamster ovary; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GLP-1; glucagon-like peptide-1; GPCR; G protein-coupled receptor; iCa2+; intracellular calcium; pERK; extracellu
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Oxyntomodulin; Neuroprotection; Stroke; Glucagon-like peptide-1 receptor; Glucagon receptor; Glutamate excitotoxicity; Oxidative stress;
Keywords: گیرنده پپتید-1 مانند گلوکاگون; AD; Alzheimer's disease; APP/PS1; amyloid precursor protein/presenilin 1; Aβ; β-amyloid; CNS; central nervous system; CTRL; control; EPM; elevated plus maze; FST; forced swimming test; GLP-1R; glucagon-like peptide-1 receptor; i.c.v.; intracerebrovent
Keywords: گیرنده پپتید-1 مانند گلوکاگون; CALHM1; calcium homeostasis modulator protein 1; CCK; cholecystokinin; CT; chorda tympani; CV; circumvallate papillae; FP; fungiform papillae; GIP; gastric inhibitory polypeptide; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; L
Keywords: گیرنده پپتید-1 مانند گلوکاگون; ADCYAP1R1 (PACAPR); adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; B2M; beta-2-microglobulin; CCKAR; cholecystokinin A receptor; CCKBR; cholecystokinin B receptor; FXR; farnesoid X receptor; CRP; C-reactive protein; GAPDH; glycera
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 receptor; Electrophysiology; Channelrhodopsin; Preproglucagon; GLP-1; PPGAP, area postrema; BNST, bed nucleus stria terminalis; DMH, dorsomedial nucleus of the hypothalamus; DMV, dorsal motor nucleus of the vagus; Ex-4, Exendin-4;
Geniposidic acid upregulates atrial natriuretic peptide secretion and lowers blood pressure in spontaneously hypertensive rats
Keywords: گیرنده پپتید-1 مانند گلوکاگون; ANP; atrial natriuretic peptide; ELE; Eucommia leaf extract; GEA; geniposidic acid; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; HR; heart rate; SBP; systolic blood pressure; SHR; spontaneously hypertensive rats; EDTA; ethylen
Glucagon-like peptide-1 receptor mediated control of cardiac energy metabolism
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1; Glucagon-like peptide-1 receptor; Insulin; Glucagon; Heart; Glucose oxidation; Fatty acid oxidation; Energy metabolism;
Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic β-cell imaging
Keywords: گیرنده پپتید-1 مانند گلوکاگون; BCM; β-cell mass; BH-Ex(9-39); Bolton-Hunter labeled exendin(9-39); DMF; N,N-dimethylformamide; FB; Fluorobenzoyl; GFP; Green fluorescent protein; GLP-1; Glucagon-like peptide-1; GLP-1R; Glucagon-like peptide-1 receptor; %ID/g; Percent injected dose per
Liposome-encapsulated clodronate specifically depletes spinal microglia and reduces initial neuropathic pain
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Liposome-encapsulated clodronate (LEC); Microglia; Spinal cord; Neuropathic pain; BAA; bulleyaconitine A; CNS; central nervous system; DAPI; 4â²,6-diamidino-2-phenylindole; GLP-1 receptor; glucagon-like peptide-1 receptor; IL; interleukin; LEC; liposome-
An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Tri-agonist; Signaling cascade; Pancreatic islets; Insulin secretion; G proteins; TRP channels; AC; Adenylyl cyclase; cAMP; Cyclic adenosine monophosphate; ECL; Extracellular loop; EPAC; Exchange protein directly activated by cAMP; FCS; Fetal calf serum;
Durability of protective effect of dulaglutide on pancreatic β-cells in diabetic mice: GLP-1 receptor expression is not reduced despite long-term dulaglutide exposure
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Apoptosis; β-cell; GLP-1 receptor; Cell proliferation; Dulaglutide; Durability; Dula; Dulaglutide; GLP-1R; Glucagon-like peptide-1 receptor; GSIS; Glucose-stimulated insulin secretion; IPITT; Intraperitoneal insulin tolerance test; TG; Triglyceride; NEFA
The glucagon-like peptide-1 (GLP-1) analog liraglutide attenuates renal fibrosis
Keywords: گیرنده پپتید-1 مانند گلوکاگون; CKD; chronic kidney disease; ESRD; end-stage renal disease; UUO; unilateral ureteral obstruction; EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; TGF-β1; transfo
GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner
Keywords: گیرنده پپتید-1 مانند گلوکاگون; ANGPTL8; angiopoietin-like protein 8; BMI; body mass index; BUN; blood urea nitrogen; DBP; diastolic blood pressure; FBG; fasting blood glucose; GLP-1R; glucagon-like peptide-1 receptor; HbA1c; glycated hemoglobin A1c; HDL-C; high-density lipoprotein chol
Replacement of the C-terminal Trp-cage of exendin-4 with a fatty acid improves therapeutic utility
Keywords: گیرنده پپتید-1 مانند گلوکاگون; DPP-IV; dipeptidyl peptidase IV; Ex-4; exendin-4; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; IPGTT; intraperitoneal glucose tolerance test; NEP 24.11; neutral endopeptidase 24.11; nGLP-1R; N-terminal extracellular domain of
Exploring the effects of DPP-4 inhibitors on the kidney from the bench to clinical trials
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 (PubChem CID: 16135499); Sitagliptin (PubChem CID: 4369359); Vildagliptin (PubChem CID: 6918537); Saxagliptin (PubChem CID: 11243969); Linagliptin (PubChem CID: 10096344); Alogliptin (PubChem CID: 11450633); AKI; acute kidney injur
Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 receptor; G protein coupled receptor; Biased agonism; Cell signaling; Peptides;
Direct effects of glucose, insulin, GLP-1, and GIP on bulbospinal neurons in the rostral ventrolateral medulla in neonatal wistar rats
Keywords: گیرنده پپتید-1 مانند گلوکاگون; aCSF; artificial cerebrospinal fluid; AP; action potential; BP; blood pressure; FAP; frequency of action potential; GIPR; glucose-dependent insulinotropic peptide receptor; GLP-1R; glucagon-like peptide-1 receptor; GLUT; glucose transporter; IML; intermed
Inhibiting receptor for advanced glycation end product (AGE) and oxidative stress involved in the protective effect mediated by glucagon-like peptide-1 receptor on AGE induced neuronal apoptosis
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 receptor; Receptor for advanced glycation end products; Oxidative stress; Diabetes; Alzheimer's disease;
Obestatin promotes proliferation and survival of adult hippocampal progenitors and reduces amyloid-β-induced toxicity
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Obestatin; Hippocampal progenitors; Cell survival; PI3K/Akt; GSK-3β/β-catenin; Amyloid beta peptide; AHP; adult rat hippocampal progenitor cells; Aβ; amyloid-beta peptide; AD; Alzheimer's disease; BrdU; 5-bromo-2-deoxyuridine; BSA; bovine serum albumin
Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/β-endorphin pathway
Keywords: گیرنده پپتید-1 مانند گلوکاگون; GLP-1R; glucagon-like peptide-1 receptor; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyltetrazolium chloride; i.c.v.; intracerebroventricular; ANOVA; analysis of variance; Glucagon-like peptide-1 receptor (GLP-1R); β-endorphin; Microglia; N
Hyperglycemia-induced GLP-1R downregulation causes RPE cell apoptosis
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Diabetic retinopathy; Glucagon-like peptide-1 receptor; Reactive oxygen species; Endoplasmic reticulum stress; P53;
Exenatide exerts a PKA-dependent positive inotropic effect in human atrial myocardium
Keywords: گیرنده پپتید-1 مانند گلوکاگون; cAMP; cyclic adenosine monophosphate; Epac; cAMP-activated guanine nucleotide exchange factor; ERK; extracellular signal-regulated kinase; GLP-1R; glucagon-like peptide-1 receptor; GLUT-1/4; glucose transporter 1/4; PKA; protein kinase A; PLB; phospholamb
Simultaneous quantification of the glucagon-like peptide-1 (GLP-1) and cholecystokinin (CCK) receptor agonists in rodent plasma by on-line solid phase extraction and LC–MS/MS
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 receptor; Cholecystokinin-1 receptor; LC–MS/MS; Solid phase extraction; Pharmacokinetics; Pharmacodynamics
Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor
Keywords: گیرنده پپتید-1 مانند گلوکاگون; PPARβ/δ; peroxisome proliferator-activated receptor β/δ; GLP-1R; glucagon-like peptide-1 receptor; GW; GW501516; PA; palmitate; qPCR; quantitative polymerase chain reaction; SREBP-1c; sterol regulatory element binding protein-1c; GSIS; glucose-stimula
Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection ab
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1; Glucagon-like peptide-1 receptor; Ischemia; Myocardial infarction; Cardiomyopathy; Heart failure; IncretinGLP-1, glucagon-like peptide-1; GLP-1R, glucagon-like peptide-1 receptor; tGLP-1, truncated forms of GLP-1 such as GLP-1(9–3
Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Bone mineral density; Exendin-4; Glucagon-like peptide-1 receptor; Osteocytes; Sclerostin;
Amylin and GLP-1 target different populations of area postrema neurons that are both modulated by nutrient stimuli
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Food intake; Glucagon-like peptide-1 receptor; Exendin; Brainstem; Area postrema
Short communication: Expression of peptide YY, proglucagon, neuropeptide Y receptor Y2, and glucagon-like peptide-1 receptor in bovine peripheral tissues
Keywords: گیرنده پپتید-1 مانند گلوکاگون; peptide YY; proglucagon; Y2 receptor; glucagon-like peptide-1 receptor;
Endocrine PharmacologyA physiological role of glucagon-like peptide-1 receptors in the central nervous system of Suncus murinus (house musk shrew)
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1 receptor; Exendin-4; Exendin (9-39); Central nervous system; Glucose-lowering effect; Suncus murinus;
Glucagon-like peptide-1 receptor gene polymorphism (Leu260Phe) is associated with morning cortisol in preschoolers
Keywords: گیرنده پپتید-1 مانند گلوکاگون; CRF; corticotrophin releasing factor; DELFIA; dissociation-enhanced lanthanide fluorescent immunoassay; GLP-1; glucagon-like peptide-1; GLP-1R; glucagon-like peptide-1 receptor; HPA; hypothalamic-pituitary-adrenal; OMIM; online Mendelian inheritance i
GLP-1 receptor antagonist as a potential probe for pancreatic β-cell imaging
Keywords: گیرنده پپتید-1 مانند گلوکاگون; Glucagon-like peptide-1; Glucagon-like peptide-1 receptor; Exendin-4; Exendin(9-39); β-Cell imaging; Islet imaging; Molecular imaging; β-Cell mass; Diabetes