Insulin stimulates GLUT4 translocation in the semitendinosus muscle of Shetland ponies
Keywords: Skeletal muscle; GLUT4; 3-O-Methylglucose; Insulin; Shetland pony
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Reduced glucose transporter GLUT4 in skeletal muscle predicts insulin resistance in non-diabetic chronic heart failure patients independently of body composition
Keywords: Chronic heart failure; Insulin resistance; GLUT4; Skeletal muscle; Metabolism
GLUT4 molecules are recruited at random for insertion within the plasma membrane upon insulin stimulation
Keywords: Glucose transporter type 4; Insulin-responsive glucose transporter; Protein translocation; Protein trafficking; Insulin; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; GLUT4; insulin-responsive glucose transporter 4; GSC; GLUT4 s
Fatty acid transport across the cell membrane: Regulation by fatty acid transporters
Keywords: FABPc; cytoplasmic fatty acid-binding protein; FABPpm; plasma membrane fatty acid-binding protein; FATP; fatty acid transport protein; GLUT4; glucose transporter-4; ACS; acyl-CoA synthetase; CPT; carnitine palmitoyltransferase; AMPK; AMP-activated kinase;
Daidzein and the daidzein metabolite, equol, enhance adipocyte differentiation and PPARγ transcriptional activity
Keywords: Daidzein; Equol; PPARγ; Adipocyte differentiation; Insulin sensitivity; GLUT4
Purification and characterization of mammalian glucose transporters expressed in Pichia pastoris
Keywords: Glucose transporter; GLUT1; GLUT4; Membrane protein purification
Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue
Keywords: Stearoyl-coenzyme A desaturase; Adipose tissue; GLUT1; GLUT4; Adiponectin
Insulin mimetic impact of Catechin isolated from Cassia fistula on the glucose oxidation and molecular mechanisms of glucose uptake on Streptozotocin-induced diabetic Wistar rats
Keywords: Diabetes mellitus; Catechin; GLUT4; Insulin; C-peptide; 14C-glucose oxidation
Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats
Keywords: bw, Body weight; CND, Cinnamaldehyde; STZ, streptozotocinCinnamaldehyde; Glycogen; GLUT4; Insulin; Pancreatic β cells
Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling
Keywords: GLUT4; Thiazolidinedione; Rosiglitazone; Diabetes type 2; Insulin resistance; Adipocyte
Effect of M35, a neuropeptide galanin antagonist on glucose uptake translated by glucose transporter 4 in trained rat skeletal muscle
Keywords: Galanin; Exercise; M35; GLUT4; Insulin
Kaempferitrin inhibits GLUT4 translocation and glucose uptake in 3T3-L1 adipocytes
Keywords: GLUT4; Kaempferitrin; 3T3-L1 adipocytes; Glucose uptake; GLUT4 translocation; QLS site; Molecular docking
YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes
Keywords: Insulin resistance; YM201636; PIKfyve; Antiretroviral therapy; Glucose transport; GLUT4; PI 3-kinase; Insulin action
Developmentally spliced PKCβII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport
Keywords: PKCβII; GLUT4; Akt; mTORC2;
RAPGEF1 gene variants associated with type 2 diabetes in the Korean population
Keywords: Type 2 diabetes; RAPGEF1; C3G; Glut4; SNPs
Time-dependent regulation of muscle caveolin activation and insulin signalling in response to high-fat diet
Keywords: Caveolin phosphorylation; Cafeteria diet; Insulin receptor; Prediabetes; Skeletal muscle; GLUT4
MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes
Keywords: MicroRNA; GLUT4; Cardiomyocyte
Lysophosphatidylserine regulates blood glucose by enhancing glucose transport in myotubes and adipocytes
Keywords: Lysophosphatidylserine; Glucose lowering; Glucose uptake; GLUT4; Myotubes; Adipocytes; Insulin; Diabetes
Impact of excess aldosterone on glucose homeostasis in adult male rat
Keywords: Glucose homeostasis; Type-II diabetes; Aldosteronism; GLUT2; GLUT4; Skeletal muscle and liver
Additive effects of insulin and muscle contraction on fatty acid transport and fatty acid transporters, FAT/CD36, FABPpm, FATP1, 4 and 6
Keywords: Giant vesicle; Electrical stimulation; Plasma membrane; Muscle; Membrane translocation; GLUT4
Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes
Keywords: Kaempferitrin; Cinnamomum osmophloeum Kaneh; Insulin signaling pathway; GLUT4; Adiponectin; Insulin resistance
Salacia oblonga extract increases glucose transporter 4-mediated glucose uptake in L6 rat myotubes: Role of mangiferin
Keywords: GLUT4; L6-myotubes; Salacia oblonga extracts; Mangiferin; 2-DG uptake; 5′-AMP-activated kinaseAICAR, 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; AGIs, inhibitors of intestinal α-glycosidases; 5′-AMPK, 5′-AMP-activated protein kinase; 2-DG, 2-deox
17β-Estradiol treatment is unable to reproduce p85α redistribution associated with gestational insulin resistance in rats
Keywords: Insulin resistance; 17β-Estradiol; Glut4; p85α; IRS-1; Pregnancy
Progression of human bone marrow stromal cells into both osteogenic and adipogenic lineages is differentially regulated by structural conformation of collagen I matrix via distinct signaling pathways
Keywords: BMSCs; bone marrow stromal cells; NC I; native collagen I matrix; DC I; denatured collagen I matrix; ERK; Extracellular signal-regulated kinase; p38; p38 mitogen-activated protein kinase; Raf or Raf-1; serine/threonine-specific kinase in ERK activating ca
The potential role of green tea catechins in the prevention of the metabolic syndrome - A review
Keywords: BMI; body mass index; COMT; catechol-O-methyl-transferase; EC; (â)-epicatechin; ECG; (â)-epicatechin-3-gallate; EGC; (â)-epigallocatechin; EGCG; (â)-epigallocatechin-3-gallate; HDL; high density lipoprotein; IDF; International Diabetes Federation;
Identification of Glypican3 as a novel GLUT4-binding protein
Keywords: GLUT4; 3T3-L1 Adipocytes; GPC3
Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome
Keywords: PIK3R1; GLUT4; insulin signaling; polycystic ovary syndrome; polymorphism; insulin resistance
The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells
Keywords: AICAR; IL-6; IL-8; GLUT4; AMPK; Human adipose tissue; Human skeletal muscle; Rat skeletal muscle
ATM protein kinase mediates full activation of Akt and regulates glucose transporter 4 translocation by insulin in muscle cells
Keywords: A-T; Ataxia-telangiectasia; IR; Insulin receptor; IRS-1; Insulin receptor substrate 1; ATM; A-T mutated; PI 3-kinase; Phosphotidylinositol 3-kinase; GLUT4; Glucose transporter 4; QUICKI; Quantitative Insulin Sensitivity Check Index; GFP; Green fluorescenc
Dangnyohwan improves glucose utilization and reduces insulin resistance by increasing the adipocyte-specific GLUT4 expression in Otsuka Long-Evans Tokushima Fatty rats
Keywords: Dangnyohwan; GLUT4; Adipocytes; Insulin resistance; OLETF rat
Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4
Keywords: Insulin; CD36; GLUT4; Translocase; Long-chain fatty acid; Translocation; Signal transduction; CHO cells; Immuno-fluorescence microscopy; Membrane permeabilization
PIKfyve: Partners, significance, debates and paradoxes
Keywords: PIKfyve; PtdIns3,5P2; PtdIns5P; Endosome fusion; Endosome fission; Sac3; ArPIKfyve; Endosomal trafficking; GLUT4;
Dioscorea opposita reverses dexamethasone induced insulin resistance
Keywords: Dioscorea opposita; Insulin resistance; Dexamethasone; 3T3-L1 adipocytes; GLUT4
Synip phosphorylation is required for insulin-stimulated Glut4 translocation
Keywords: VAMP2; vesicle-associated membrane protein 2; Glut4; glucose transporter 4; Akt2; Insulin; Glucose transporter 4 (Glut4); Synip; Syntaxin4;
PACSIN3 overexpression increases adipocyte glucose transport through GLUT1
Keywords: Adipocyte; Endocytosis; GLUT1; GLUT4; PACSIN3; Membrane trafficking; Syndapin
A novel method to monitor insulin-stimulated GTP-loading of Rab11a in cardiomyocytes
Keywords: Rab11a; GLUT4; Akt; GTP-loading;
Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells
Keywords: GLUT4; AS160; Rab-GAP; Rab8; Rab10; Rab14; Insulin; Akt; Vesicle traffic; Muscle cells
Peptide rescues GLUT4 recruitment, but not GLUT4 activation, in insulin resistance
Keywords: GLUT; glucose transporter; DMEM; Dulbecco's modified Eagle's medium; HA; hemagglutinin; EGFP; enhanced green fluorescent protein; GLUT4; GLUT1; Recruitment to the plasma membrane; Glucose uptake; Insulin resistance; Phosphoinositide-binding peptide;
The depletion of cellular mitochondrial DNA causes insulin resistance through the alteration of insulin receptor substrate-1 in rat myocytes
Keywords: IRS, insulin receptor substrate; GLUT4, facilitative glucose transporter isoform 4; PI3K, phosphatidylinositol 3-kinase; PDK-1, 3-phosphoinositide-dependent protein kinase-1; Akt2/PKB, protein kinase BmtDNA; GLUT4; Insulin resistance; IRS-1; Akt2/PKB
FIP2 and Rip11 specify Rab11a-mediated cellular distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells
Keywords: Rab11a; FIP2; Rip11; H9c2 cells; GLUT4; FAT/CD36
How many signals impinge on GLUT4 activation by insulin?
Keywords: GLUT4; Actin remodeling; Rab; Rho
Ginsenoside Rb1 promotes adipogenesis in 3T3-L1 cells by enhancing PPARγ2 and C/EBPα gene expression
Keywords: Ginsenosides Rb1; Adipogenesis; 3T3-L1 adipocytes; PPARγ; C/EBPα; Proliferation; GLUT1; GLUT4
Muscle GLUT4 in cirrhosis
Keywords: OGTT; oral glucose tolerance test; NGT; normal glucose tolerance; IGT; impaired glucose tolerance; DM; diabetes mellitus; RT-PCR; reverse transcriptase polymerase chain reaction; HOMA; homeostasis model assessment; GEC; galactose elimination capacity; ANO
Age related obesity-induced shortening of GLUT4 mRNA poly(A) tail length in rat gastrocnemius skeletal muscle
Keywords: Obesity; Insulin resistance; GLUT4; Poly(A) tail; RNase H assay; PAT assay
Distribution patterns of the glucose transporters GLUT4 and GLUT1 in skeletal muscles of rats (Rattus norvegicus), pigs (Sus scrofa), cows (Bos taurus), adult goats, goat kids (Capra hircus), and camels (Camelus dromedarius)
Keywords: Camel; Cow; GLUT1; GLUT4; Goat; Pig; Rat; Skeletal muscles
Caudal hindbrain lactate infusion alters glucokinase, SUR1, and neuronal substrate fuel transporter gene expression in the dorsal vagal complex, lateral hypothalamic area, and ventromedial nucleus hypothalamus of hypoglycemic male rats
Keywords: Lactate; Insulin; MCT2; GLUT3; GLUT4; Dorsal vagal complex; Ventromedial nucleus hypothalamus; Lateral hypothalamic area
GLUT4 translocation: The last 200 nanometers
Keywords: GLUT4; Insulin; Adipocyte; AS160; TIRF microscopy
Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of porcine preadipocyte in vitro
Keywords: 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; Glut4; glucose transporter 4; GPDH; glycerol-3-phosphate dehydrogenase; LPL; lipoprotein lipase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PEPCK; phosphoenolpyruvate carboxykinase; PPARγ; pe
Lentivirus-mediated downregulation of hypothalamic insulin receptor expression
Keywords: Adiposity; Leptin; SOCS3; GLUT4; Arcuate nucleus; Hippocampus
Structure of the bovine VASAP-60/PRKCSH gene, functional analysis of the promoter, and gene expression analysis
Keywords: AGE-R2; advanced glycation end products-receptor 2; αGII; alpha subunit of glucosidase II; βGII; beta subunit of glucosidase II; CL; corpora lutea; DF; dominant follicle; ER; endoplasmic reticulum; FGF-1; fibroblast growth factor-1; GAPD; glyceraldehyde