Keywords: اسید گلیکوزید سدیم اسید; Intrahepatic cholestasis of pregnancy; Serum bile acid; Pseudo-targeted method; Metabolomics; UPLC-triple TOF-MS/MS; Diagnostic and therapeutic profiles; ICP; Intrahepatic cholestasis of pregnancy; TBA; total bile acids; UDCA; ursodeoxycholic acid; LCA; l
مقالات ISI اسید گلیکوزید سدیم اسید (ترجمه نشده)
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Keywords: اسید گلیکوزید سدیم اسید; ASBT; apical sodium-dependent bile acid transporter; BMI; body mass index; CA; cholic acid; CA-D4; cholic acidâ2,2,4,4âD4; CARB; Carbohydrate and Related Biomarkers; CDCA; chenodeoxycholic acid; CRP; C-reactive protein; CV; coefficient of variation; D
Keywords: اسید گلیکوزید سدیم اسید; ASBT; apical sodium-dependent bile acid transporter; ASDs; amorphous solid dispersions; BACS; bile acid-CoA synthase; BAT; bile acid-amino acid transferase; BCS; biopharmaceutics classification system; BSH; bile salt hydrolase; C4; 7α-hydroxy-4-cholesten
Keywords: اسید گلیکوزید سدیم اسید; ABCB; ATP-binding cassette sub-family B; Apo; apolipoprotein; ASBT; apical sodium dependent bile acid transporter; BDL; bile duct ligation; BSEP; bile salt export pump; CA; cholic acid; CDCA; chenodeoxycholic acid; C/EBP; CCAAT-enhancer-binding protein; C
Keywords: اسید گلیکوزید سدیم اسید; ANT; adenine nucleotide translocator; Cyt C; cytochrome C; Cys A; cyclosporine A; FCCP; carbonylcyanide-p-(trifluoromethoxy) phenyl-hydrazone; GCDCA; glycochenodeoxycholic acid; IM; inner membrane; MβCD; methyl-β-cyclodextrin; MMP; mitochondrial membran
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition
Keywords: اسید گلیکوزید سدیم اسید; ALT; alanine amino transferase; AST; aspartate amino transferase; AUClast; area under the plasma time curve from time 0 to the last measured concentration (24Â h); BSEP; Bile Salt Export Pump; CL; clearance; C0; highest initial plasma concentration of dru
Glycochenodeoxycholic Acid Does Not Increase Transforming Growth Factor-Beta Expression in Bile Duct Epithelial Cells or Collagen Synthesis in Myofibroblasts
Keywords: اسید گلیکوزید سدیم اسید; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GCDCA; glycochenodeoxycholic acid; PCR; Polymerase chain reaction; TGF-β; transforming growth factor-beta; bile acids; primary sclerosing cholangitis; bile duct epithelial cells; phosphatyl
Deletion of liver-specific STAT5 gene alters the expression of bile acid metabolism genes and reduces liver damage in lithogenic diet-fed mice
Keywords: اسید گلیکوزید سدیم اسید; STAT5; signal transducer and activator of transcription 5; GH; growth hormone; IGF-1; insulin-like growth factor-1; LDLR; low-density lipoprotein receptor; STAT5 LKO; liver-specific STAT5 knock-out; STAT5 fl/fl; STAT5 flox/flox; TG; triacylglycerol; ChMCs
Improved synthesis of glycine, taurine and sulfate conjugated bile acids as reference compounds and internal standards for ESI-MS/MS urinary profiling of inborn errors of bile acid synthesis
Keywords: اسید گلیکوزید سدیم اسید; EEDQ; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; DEPC; diethyl phosphorocyanidate; DPPA; diphenyl phosphoryl azide; SO3-TEA; sulfur trioxide-triethylamine complex; SO3-TMA; sulfur trioxide-trimethylamine complex; SO3-DMA; sulfur trioxide-N,N-dimethyl
Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis
Keywords: اسید گلیکوزید سدیم اسید; LCA; lithocholic acid; UDCA; ursodeoxycholic acid; CDCA; chenodeoxycholic acid; DCA; deoxycholic acid; CA; cholic acid; TCA; taurocholic acid; GCDC; glycochenodeoxycholic acid; TCDC; taurochenodeoxycholic acid; GCA; glycocholic acid; GDCA; glycodeoxycholi
GCDCA down-regulates gene expression by increasing Sp1 binding to the NOS-3 promoter in an oxidative stress dependent manner
Keywords: اسید گلیکوزید سدیم اسید; Cholestatic liver disease; Endothelial nitric oxide synthase; Oxidative stress; Transcription factor Sp1; Glycochenodeoxycholic acid; ADHP; 0-acetyl-3, 7-dihydroxyphenoxazine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BDL; bile duct
UPLC-MS-based serum metabonomics for identifying acute liver injury biomarkers in Chinese miniature pigs
Keywords: اسید گلیکوزید سدیم اسید; ALB; albumin; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATP; adenosine triphosphate; BPI; base peak intensity; CDP-choline; cytidine diphosphate choline; CHO; cholesterol; Cr; creatinine; ESI; electrospray ionization; FAAH; fatty aci
Hepatocyte-based in vitro model for assessment of drug-induced cholestasis
Keywords: اسید گلیکوزید سدیم اسید; ALT; alanine aminotransferase; ALP; aspartate aminotransferase; BAs; bile acids; BSEP/Bsep; bile salt export pump (human/rat); DICI; drug-induced cholestasis index; DMSO; dimethyl sulfoxide; TCA; taurocholic acid; CA; cholic acid; FBS; fetal bovine serum;
Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis
Keywords: اسید گلیکوزید سدیم اسید; Glycochenodeoxycholic acid; Sphingosine kinase; Calcium oscillation; Cholestatic liver disease; Sphingosine-1 phosphate; Sphingosine-1 phosphate receptor;
Disruption of Stard10 gene alters the PPARα-mediated bile acid homeostasis
Keywords: اسید گلیکوزید سدیم اسید; StAR; steroidogenic acute regulatory protein; START; StAR-related lipid transfer; STARD10/Stard10; START domain containing 10; WT; wild type; ASBT/Asbt; apical sodium dependent bile acid transporter; STARD2/Stard2; START domain containing 2; CA; cholic ac
Mitochondrial genome depletion in human liver cells abolishes bile acid-induced apoptosis: Role of the Akt/mTOR survival pathway and Bcl-2 family proteins
Keywords: اسید گلیکوزید سدیم اسید; ABC; ATP-binding cassette; Akt; protein kinase B; BCRP; Breast cancer resistance protein; BSEP; Bile salt export pump; DCA; Deoxycholic acid; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; ERK; Extracellular regulated kinase; EtBr; Ethidium bromide; GC
Differential activation of the human farnesoid X receptor depends on the pattern of expressed isoforms and the bile acid pool composition
Keywords: اسید گلیکوزید سدیم اسید; Glycoconjugated bile acids; Tauroconjugated bile acids; Ileum; Liver; Nuclear receptor; ACA; allocholic acid; BA; bile acid; BSEP; bile salt export pump; CDCA; chenodeoxycholic acid; CA; cholic acid; DCA; deoxycholic acid; FGF; fibroblast growth factor; F
Bile acid profiling in human biological samples: Comparison of extraction procedures and application to normal and cholestatic patients
Keywords: اسید گلیکوزید سدیم اسید; CA; cholic acid; CDCA; chenodeoxycholic acid; CV; coefficient of variation; DCA; deoxycholic acid; GCA; glycocholic acid; GCDCA; glycochenodeoxycholic acid; GC-MS; gas chromatography coupled to mass spectrometry; GDCA; glycodeoxycholic acid; GLCA; glyco
Calcium-dependent nitric oxide production is involved in the cytoprotective properties of n-acetylcysteine in glycochenodeoxycholic acid-induced cell death in hepatocytes
Keywords: اسید گلیکوزید سدیم اسید; Activator protein 1; AP-1; Anion superoxide; O2â; 2,7- dichlorofluorescein diacetate; DCFDA; (Z)-1-[2-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate; NONOate; dihydroethidium; DHE; glycochenodeoxycholic acid; GCDCA; reduced glutathione;
Bile acid toxicity structure-activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A)
Keywords: اسید گلیکوزید سدیم اسید; GCA; glcyocholic acid; GCDCA; glycochenodeoxycholic acid; GDCA; glycodeoxycholic acid; GUDCA; glycoursodeoxycholic acid; HSA; hydrophobic surface area; HCA; hyocholic acid; NCA; nutriacholic acid; UCA; ursocholic acid; PSA; polar surface area; TCA; tauroc
Free fatty acids sensitize hepatocytes to bile acid-induced apoptosis
Keywords: اسید گلیکوزید سدیم اسید; Apoptosis; Bile acid; Cholestasis; Glycochenodeoxycholic acid; Interleukin; Liver; Nonalcoholic; Oleic acid; Steatosis
Interaction between caspase-8 activation and endoplasmic reticulum stress in glycochenodeoxycholic acid-induced apoptotic HepG2 cells
Keywords: اسید گلیکوزید سدیم اسید; Apoptosis; Endoplasmic reticulum; Caspase; Glycochenodeoxycholic acid; HepG2 cells
Involvement of endoplasmic reticulum in glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes
Keywords: اسید گلیکوزید سدیم اسید; Apoptosis; Endoplasmic reticulum; Hepatocytes; Glycochenodeoxycholic acid
The effect of ursodeoxycholic acid on glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes
Keywords: اسید گلیکوزید سدیم اسید; Apoptosis; Bile acid; Hepatocytes; Ursodeoxycholic acid; Glycochenodeoxycholic acid;
Bile acids induce hepatic stellate cell proliferation via activation of the epidermal growth factor receptor
Keywords: اسید گلیکوزید سدیم اسید; BrdU; bromodeoxyuridine; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; GCDCA; glycochenodeoxycholic acid; HSC; hepatic stellate cell; JNK; c-Jun N-terminal kinase; MEK; mitogen-activated
Increased susceptibility of fat-laden Zucker-rat hepatocytes to bile acid-induced oncotic necrosis: An in vitro model of steatocholestasis
Keywords: اسید گلیکوزید سدیم اسید; ALT; alanine aminotransferase; AP; alkaline phosphatase; AST; aspartate aminotransferase; BSA; bovine serum albumin; CSA; cyclosporin A; ÎΨ; mitochondrial membrane potential; DAPI; 4,6-diamino-2-phenylindole; DCF; 2,7â²-dichlorofluorescein; DCF-DA; dic