Keywords: AIC; Akaike information criterion; BIC; Bayesian information criterion; DLD; Department of Livestock Development (Thailand); ERGM; exponential random graph model; GOF; goodness of fit; MCMC; Markov chain Monte Carlo; MCMCMLE; Monte Carlo Markov chain maxi
مقالات ISI (ترجمه نشده)
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Keywords: Mathematical modelling; Sexually transmitted infections; Human papillomavirus; Sexual behavior; Sexual mixing; SPAR; sex partner acquisition rate, or the number of new partners in a given time period; Natsal-3; National Survey on Sexual Attitudes and Life
Keywords: HPPD; p-hydroxyphenylpyruvate-dioxygenase; TSR; target-site resistance; NTSR; non-target-site resistance; CFS; Curtiss Farm mesotrione-susceptible; HCR; Henry County mesotrione-resistant; DAT; days after treatment; GOF; goodness-of-fit; OR; odds ratio; Wa
Keywords: LiDAR; LiDAR intensity; Tidewater glacier; Calving; South Shetland Islands; Antarctica; AC; Analysed Cloud; AIC; Akaike Information Criterion; ALS; Airborne Laser Scanning; AP; Antarctic Peninsula; CP; Control Point; DEM; Digital Elevation Model; E; Nash-
Keywords: Biosecurity; Dual use research of concern; DURC; GOF; BWTC; Bioviolence; Bioterrorism; Self-governance; Bioethics; Biological risk management; Dual-use export control;
Keywords: Personalized medicine; primary immunodeficiency disorders; immune dysregulation; autoimmunity; therapy; mutation; APDS; Activated phosphoinositide 3-kinase syndrome; CMC; Chronic mucocutaneous candidiasis; CTLA4; Cytotoxic lymphocyte antigen 4; GOF; Gain
Keywords: Executive recruitment; Industry origin; Managerial performance; Shareholder value; Social network analysis; Exponential random graph models; ERGM; exponential random graph model; GoF; goodness of fit; NACE; statistical classification of economic activitie
Keywords: GOF; Covalent modification; Flux; Filtration; Wastewater treatment;
Keywords: FTFI; Fungicide Treatment Frequency Index; FRAC; Fungicide Resistance Action Committee; GoF; goodness-of-fit; HTFI; Herbicide Treatment Frequency Index; HRAC; Herbicide Resistance Action Committee; ITFI; Insecticide Treatment Frequency Index; IRAC; Insect
Keywords: GOF; Gain-of-function; STAT1; Signal transducer and activator of transcription 1; CMCD; Chronic mucocutaneous candidiasis disease; CCD; Coiled-coiled domain; DBD; DNA-binding domain; LOF; Loss-of-function; AR; Autosomal recessive; AD; Autosomal dominant
Keywords: AB; attitude toward a behavior; B; behavior; CFA; confirmatory factor analysis; CFI; comparative fit index; EFA; exploratory factor analysis; EEF; eco-environment fragile; GFI; goodness of fit index; GOF; Goodness-of-Fit; GTGP; Grain to Green Program; IN;
Keywords: Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: ASCVD; atherosclerotic cardiovascular disease; CHD; coronary heart disease; CVD; cardiovascular disease; CYP; cytochrome; EAS; European Atherosclerosis Society; FDA; Food and Drug Administration; FH; Familial hypercholesterolemia; GOF; gain of function; H
Keywords: GOF; goodness of fit; RMSE; root mean squared error; KW; Kruskal-Wallis H-test; DFA; discriminant function analysis; PCA; principal components analysis; Sediment fingerprinting; Mixing model; Sediment source ascription; Sediment contribution; River catc
Keywords: ADA; adenosine deaminase; AIRE; autoimmune regulator; AML; acute myeloid leukemia; APECED; autoimmune polyendocrinopathy, candidiasis, and ectodermal dysplasia; APLAID; autoinflammation and PLCγ2-associated antibody deficiency and immune dysregulation; A
Keywords: ANOVA; analysis of variance; ECD; equivalent current dipole; EEG; electroencephalography; fMRI; functional magnetic resonance imaging; GOF; goodness of fit; MEG; magnetoencephalography; MRI; magnetic resonance imaging; PCC; posterior cingulate cortex; PET
Keywords: Watershed modeling; Eutrophication; Runoff; Great Lakes; Lake Erie; Allochthonous inputs; Non-point source pollution; Algal bloom; SWAT; Soil and Water Assessment Tool; DLBRM; Distributed Large Basin Runoff Model; HSPF; Hydrology Simulation Program-Fort
Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
PCSK9 inhibition alters the lipidome of plasma and lipoprotein fractions
Keywords: PCSK9; Lipidomics; Lipoproteins; Atherosclerosis; Sphingolipids; Drug therapy; CAD; coronary artery disease; CE; cholesteryl ester; Cer; ceramide; DAG; diacylglycerol; Gb3; globotriasoylceramide; Glc/GalCer; glucosyl/galactosylceramide; GOF; gain-of-funct
Peripheral vascular atherosclerosis in a novel PCSK9 gain-of-function mutant Ossabaw miniature pig model
Keywords: GOF; gain of function; PCSK9; proprotein convertase subtilisin/kexin type-9; WT; wild-type; AD; atherogenic diet; MDCT; multidetector computed tomography; LDL-C; low-density lipoprotein cholesterol; ND; normal diet; IVUS; intravascular ultrasound; BOLD-MR
Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations
Keywords: Signal transducer and activator of transcription 1, gain of function; natural killer cell deficiency; perforin; Janus kinase inhibition; ruxolitinib; natural killer cell maturation; ADCC; Antibody-dependent cellular cytotoxicity; CCD; Coiled-coil domain;
Patterns of clustering of the metabolic syndrome components and its association with coronary heart disease in the Multi-Ethnic Study of Atherosclerosis (MESA): A latent class analysis
Keywords: LCA; latent class analysis; MetS; metabolic syndrome; BMI; body mass index; CHD; coronary heart disease; CVD; cardiovascular disease; HDL; high density lipoprotein; NCEP-ATP III; National Cholesterol Education Program Adult Treatment Panel III; MESA; Mult
CRISPLD1 rs12115090 polymorphisms alters antiplatelet potency of clopidogrel in coronary artery disease patients in Chinese Han
Keywords: CAD; coronary artery disease; ACS; acute coronary syndrome; DAPT; dual antiplatelet therapy; PCI; percutaneous coronary intervention; SNPs; single nucleotide polymorphisms; LD; loading dose; MD; maintain dose; PRI; platelet reaction index; HTPR; high on-t
Prediction of human pharmacokinetics of activated recombinant factor VII and B-domain truncated factor VIII from animal population pharmacokinetic models of haemophilia
Keywords: rFVIIa; activated recombinant factor VII; rFVIII; recombinant factor VIII; PK; pharmacokinetic; pcVPC; prediction corrected visual predictive check; IIV; inter-individual variability; RSE; relative standard error; GOF; goodness-of-fit; Allometric scaling;
Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles
Keywords: Connexin43; Transcriptional regulation; Cardiac development; Cardiac electrophysiology; Wnt signaling, Ventricular tachycardia; SHF; Second heart field; RV; Right ventricle; LV; Left ventricle; ACM; Arrhythmogenic cardiomyopathy; GOF; Gain-of-function; LO
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function
Keywords: Signal transducer and activator of transcription 1; gain of function; sumoylation; small ubiquitin-related modifier; IFN-γ; Rhodococcus species infection; CMC; Chronic mucocutaneous candidiasis; GFP; Green fluorescent protein; GOF; Gain of function; IP10
The role of STIM1 and SOCE in smooth muscle contractility
Keywords: Stromal interaction molecule 1 (STIM1); Store-operated calcium entry; Store-operated calcium channels; Smooth muscle contraction; Ca2+; calcium; CSM; cavernous smooth muscle; CPA; cyclopiazonic acid; [Ca2+]; icytoplasmic calcium concentration; GoF; gain o
Compound heterozygous KCNQ1 mutations (A300T/P535T) in a child with sudden unexplained death: Insights into possible molecular mechanisms based on protein modeling
Keywords: aa; amino acid; BWA; Burrows-Wheeler aligner; CaM; calmodulin; CPR; cardiopulmonary resuscitation; DNA; deoxyribonucleic acid; ECG; electrocardiogram; GOF; gain of function; KCNE1; potassium voltage-gated channel subfamily E member 1; Kv7.1; voltage-gated
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Keywords: STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
Keywords: Activated phosphoinositide 3-kinase δ syndrome; p110δ-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency; phosphoinositide 3-kinase δ; PIK3CD gene; bronchiectasis; immunodeficiency; hematopoietic stem cell transplanta
Force regulated conformational change of integrin αVβ3
Keywords: Ab; antibody; BFP; biomembrane force probe; BSA; bovine serum albumin; Fg; fibrinogen; FNIII7-10; fibronectin module III domain 7-10; GOF; gain-of-function; MT; mutant; SA; streptavidin; WT; wild type; Biomechanics; Integrin αVβ3; Integrin conformat
Effortful control and resting state networks: A longitudinal EEG study
Keywords: ACC; anterior cingulate cortex; AIns; anterior insula; ANOVA; analysis of variance; BEM; boundary element model; BOLD; blood oxygen level dependent; CEN; central executive network; DlPFC; dorsolateral prefrontal cortex; DMN; default mode network; EC; effo
Free thiol groups in von Willebrand factor (VWF) are required for its full function under physiological flow conditions
Keywords: ADAMTS-13; a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13; DTT; dithiothreitol; ECM; extracellular matrix; ELISA; enzyme linked immunosorbent assay; FVIII; coagulation factor VIII; GOF; gain-of-function; GPIb; glycoprote
Normal hematopoiesis and lack of β-catenin activation in osteoblasts of patients and mice harboring Lrp5 gain-of-function mutations
Keywords: GOF; Gain-of-function; AML; Acute myeloid leukemia; LSK; HSC-enriched Linâ Sca-1+Â c-Kit+ cells; LT-HSC; Long-term hematopoietic stem cell; ST-HSC; Short-term hematopoietic stem cell; MPP; Multipotent progenitor; CMP; Common myeloid progenitor; GMP; Gra
VEGF regulates relative allocation of Isl1+ cardiac progenitors to myocardial and endocardial lineages
Keywords: VEGF; Isl1; Flk1; Multipotent cardiac progenitors; A; atrium; CPCs; cardiac progenitor cells; C-Casp3; cleaved caspase-3; GOF; gain-of function; HPF; per high power field; IB4; Isolectin B4; ISH; in situ hybridization; LOF; loss-of-function; MHC; myosin h
Coronary Thrombosis and Major Bleeding After PCI With Drug-Eluting Stents: Risk Scores From PARIS
Keywords: bleeding; PCI; risk; thrombosis; CrCl; creatinine clearance; CTE; coronary thrombotic event; DAPT; dual-antiplatelet therapy; DES; drug-eluting stent(s); GOF; goodness-of-fit; MB; major bleeding; MI; myocardial infarction; OR; odds ratio; PCI; percutaneou
Exome and genome sequencing for inborn errors of immunity
Keywords: Next-generation sequencing; whole-exome sequencing; whole-genome sequencing; targeted sequencing; primary immunodeficiency; AD; Autosomal dominant; AF; Allele frequency; AR; Autosomal recessive; CADD; Combined annotation-dependent depletion; CID; Combined
Biomarkers for Wilms Tumor: A Systematic Review
Keywords: biomarkers; kidney neoplasms; pediatrics; prognosis; Wilms tumor; COG; Children's Oncology Group; GOF; gain of function; LOH; loss of heterozygosity; NWTS; National Wilms Tumor Study; PRISMA; Preferred Reporting Items for Systematic Reviews and Meta-An
Common variable immunodeficiency, impaired neurological development and reduced numbers of T regulatory cells in a 10-year-old boy with a STAT1 gain-of-function mutation
Keywords: CMC; chronic mucocutaneous candidiasis; CVID; common variable immunodeficiency; FOXP3; forkhead-box protein 3; GOF; gain-of-function; STAT; signal transducer and activator of transcription; Immunodeficiency; STAT transcription factor; Cytokine signaling;
Electrophysiologic consequences of KATP gain of function in the heart: Conduction abnormalities in Cantu syndrome
Keywords: α-MHC; α-myosin heavy chain; AV; atrioventricular; AVERP; AV effective refractory period in AV node; CS; Cantu syndrome; DTG; double transgenic; ECG; electrocardiogram; ERP; effective refractory period; GOF; gain of function; Kir; inward rectifier potas
Negative and positive temperature dependence of potassium leak in MscS mutants: Implications for understanding thermosensitive channels
Keywords: CP; specific heat capacity; GOF; gain-of-function; LOF; loss-of-function; MS; mechanosensitive; NTD; negative temperature dependent; PTD; positive temperature dependent; TM; transmembrane helix; Bacteria; Channel; Mechanosensitive; Potassium; Thermosensit
Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity
Keywords: Primary immunodeficiency; combined immunodeficiency; B-cell lymphoma 10; mucosa-associated lymphoid tissue lymphoma-translocation gene 1; CARMA1; caspase recruitment domain 9; AR; Autosomal recessive; BCL10; B-cell lymphoma 10; BCR; B-cell receptor; CARD;
Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies
Keywords: Follicular helper T cells; humoral immunity; primary immunodeficiencies; cytokine signaling; Bcl-6; B-cell lymphoma 6; cTFH; Circulating follicular helper T; DN; Double-negative; DP; Double-positive; GC; Germinal center; GOF; Gain of function; IL-10R; IL-
Relationship Between ABCB1 Polymorphisms, Thromboelastography and Risk of Bleeding Events in Clopidogrel-Treated Patients With ST-Elevation Myocardial Infarction
Keywords: ADP; adenosine diphosphate; STEMI; ST-elevation myocardial infarction; PCI; percutaneous coronary intervention; PR; platelet reactivity; LOF; loss-of-function; GOF; gain-of-function; ABCB1; ATP-binding cassette, sub-family B, member 1, also called MDR1; S
Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells
Keywords: CSCs; Cancer stem cells; FISH; Fluorescent in situ hybridization; GOF; Gain of function; MMPs; Matrix metalloproteinases; Mutp53; Mutant p53; OS; Osteosarcoma; Human osteosarcoma; Cancer stem cells; Mutant p53 gain of function; Cancer cell dedifferentiati
ReviewMendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity
Keywords: AD; autosomal dominant; AR; autosomal recessive; BCG; bacillus Calmette-Guérin; CGD; chronic granulomatous disease; CMC; chronic mucocutaneous candidiasis; EM; environmental mycobacteria; GOF; gain-of-function; HSCT; hematopoietic stem cell transplantati
Steady-state MEG responses elicited by a sequence of amplitude-modulated short tones of different carrier frequencies
Keywords: AEF; auditory evoked field; AM; amplitude modulation(ed); ANOVA; analysis of variance; ASSR; auditory steady-state response; EEG; electroencephalography; fc; carrier frequency; fm; modulation frequency; GOF; goodness of fit; MEG; magnetoencephalography; M
Can magnetoencephalography track the afferent information flow along white matter thalamo-cortical fibers?
Keywords: BA3b; Brodmann area 3b; CD; Conduction Velocity; DTI; Diffusion Tensor Imaging; ECD; Equivalent Current Dipole; EEG; Electroencephalography; EPI; Echo-Planar Imaging; EPSPs; Excitatory Postsynaptic Potentials; FA; Fractional Anisotropy; fMRI; Functional M
Overcoming the heterologous bias: An in vivo functional analysis of multidrug efflux transporter, CgCdr1p in matched pair clinical isolates of Candida glabrata
Keywords: Candida glabrata; CgCDR1; Multidrug resistance; Clinical isolates; ABC; ATP binding cassette; MF; major facilitator; AR; azole resistant; AS; azole sensitive; NR; Nile Red; GOF; gain of function;
A novel mechanism for LQT3 with 2:1 block: A pore-lining mutation in Nav1.5 significantly affects voltage-dependence of activation
Keywords: Cardiac Sodium Channel; LQT3; V411M; Flecainide; Mexiletine; Lidocaine; WT; wild-type; LQTS; Long QT Syndrome; AP; action potential; ECG; electrocardiogram; GOF; gain of function; HEK; human embryonic kidney; TdP; torsades de pointes;