Keywords: Chicken; GPR120; CD36; Lipase; Fat taste; Rostrum;
مقالات ISI (ترجمه نشده)
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Keywords: Fat taste; Fat perception; BMI; Diet; 3-AFC; 3-alternative forced choice method; CanO; Canola Oil; CanOOleA; Canola Oil spiked with Oleic Acid; CD36; Cluster of differentiation 36; EDTA; Ethylenediaminetetraacetic acid; FFA; free fatty acid; FFQ; Food Fre
Keywords: AMPK; AMP-activated protein kinase; BARCIST; Brown Adipose Reporting Criteria in Imaging Studies; BAT; Brown adipose tissue; BMI; Body mass index; β1-AR; β1-adrenergic receptor; β3-AR; β3-adrenergic receptor; CIT; Cold-induced thermogenesis; CO2; diox
Keywords: Satiation; Satiety; Stomach; Neurohormonal; AA; amino acids; ARC; arcuate nucleus; BMI; body mass index; CCK; cholecystokinin; FFAR; free fatty acid receptor; GIP; glucose-dependent insulinotropic peptide; GLP; glucagon-like peptide; GPR120; G protein cou
Keywords: ER; endoplasmic reticulum; FA; fatty acid; Gpr120; G-protein-coupled receptor 120; HGO; hepatic glucose output; LA; linoleic acid (18: 2 n 6); HPA; high-palmitic-acid diet; HOA; high-oleic-acid and low-palmitic-acid diet; IL; interleukin; JNK; c-Jun N-ter
Keywords: ABCA; ATP-binding cassette transporter; AIM; Apoptosis inhibitor of macrophage; APC; antigen-presenting cell; ASC; apoptotic speck protein containing a caspase recruitment domain; AT; adipose tissue; ATM; AT macrophage; BLT; leukotriene B4 receptor; BM; b
Keywords: ACC; acetyl-coenzyme A carboxylases; ACO; acetyl-coenzyme A oxidase; ALT; alanine aminotransferase; APC; adipocyte; AST; aspartate aminotransferase; ATGL; adipose triglyceride lipase; CD68; cluster of differentiation 68; COX-2; cyclooxygenase-2; CPT1; car
Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes
Keywords: GPR120; FFAR4; N-arylpyrrole; Type 2 diabetes; GPR40; oGTT; DIO mouse;
Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design
Keywords: GPR120; Agonist biphenyl derivatives; OGTT; Type 2 diabetes;
Maternal n-3 PUFA supplementation promotes fetal brown adipose tissue development through epigenetic modifications in C57BL/6 mice
Keywords: ARA; (arachidonic acid); Cidea; (cell death-inducing DNA fragmentation factor α-like effector A); DHA; (docosahexaenoic acids); EHMT1; (euchromatic histone N-lysine methyltransferase 1); EPA; (eicosapentaenoic acids); eWAT; (epididymal white adipose tiss
Flaxseed oil rich in omega-3 protects aorta against inflammation and endoplasmic reticulum stress partially mediated by GPR120 receptor in obese, diabetic and dyslipidemic mice models
Keywords: Nutrigenomics; Obesity; Inflammation; ER stress; n-3 fatty acids; GPR120; Atherogenesis;
Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation
Keywords: Ang-II; angiotensin-II; CKD; chronic kidney disease; H2S; hydrogen sulfide; SCFA; short chain fatty acid; GYY; GYY4137 dichloromethane complex; WT; wild type; GFR; glomerular filtration rate; Olfr78; olfactory receptor 78; Rorc; RAR-related orphan recepto
The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines
Keywords: FFA; Free-fatty acid; PUFA; polyunsaturated fatty acid; DHA; docosahexaenoic acid; EPA; Eicosapentaenoic acid; OA; Oleic acid; LA; Linoleic acid; LPA; 1-oleoyl lysophosphatidic acid, LPC, lysophosphatidylcholine; EGFR; Epidermal growth factor receptor; EM
Different effects of G-protein-coupled receptor 120 (GPR120) and GPR40 on cell motile activity of highly migratory osteosarcoma cells
Keywords: GPR120; GPR40; Cell migration; Osteosarcoma cells;
Improving metabolic stability with deuterium: The discovery of GPU-028, a potent free fatty acid receptor 4 agonists
Keywords: Deuterium; FFA4 agonist; GPR120; TUG-891; Type 2 diabetes;
Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist
Keywords: Free fatty acid receptor 4; GPR120; Free fatty acid receptor 1; Phenylpropanoic acid; Type 2 diabetes;
Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists
Keywords: GPR120; Type 2 diabetes; Phenylpropanoic acid;
Aroma compound diacetyl suppresses glucagon-like peptide-1 production and secretion in STC-1 cells
Keywords: Diacetyl (PubChem CID:650); Nicardipine (PubChem CID:41114); Nitrendipine (PubChem CID:4507); Tolbutamide (PubChem CID:5505); Glucagon-like peptide 1; Diacetyl; Flavour compound; Satiety; GPR120;
Effects of arachidonic acid on FFA4 receptor: Signaling, phosphorylation and internalization
Keywords: AA; arachidonic acid; PMA; phorbol 12-myristate 13-acetate; GPCRs; G protein-coupled receptors; FFA4 phosphorylation; GPR120; FFA4 internalization; ERK phosphorylation;
Free-fatty acid receptor-4 (FFA4) modulates ROS generation and COX-2 expression via the C-terminal β-arrestin phosphosensor in Raw 264.7 macrophages
Keywords: FFA4; free-fatty acid receptor-4; ROS; reactive oxygen species; COX-2; cyclooxygenase-2; PMA; phorbol-12-myristate 13-acetate; TUG-891 (Pubchem CID 57522038); AH7614 (PubChem CID 233085).; FFA4; GPR120; Free-fatty acids; Reactive oxygen species; COX-2;
GPR120 in adipocytes has differential roles in the production of pro-inflammatory adipocytokines
Keywords: Obesity; Extracellular matrix remodeling factor; Protein kinase C; Toll-like receptors; Ï-3 polyunsaturated fatty acids; Ï-3 PUFA; Ï-3 polyunsaturated fatty acid; DHA; docosahexaenoic acid; ECM; extracellular matrix; EPA; eicosapentaenoic acid; GPR120;
Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders
Keywords: Adipose tissue; Brown fat; Nrg4; Adipokine; NAFLD; Diabetes; BAT; Brown adipose tissue; WAT; White adipose tissue; eWAT; epididymal WAT; Nrg4; Neuregulin 4; HFD; High-fat diet; TAG; Triglyceride; WT; Wild type; Tg; Transgenic; KO; Knockout; TNFα; Tumor n
Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects
Keywords: GPR120; FFAR4; Aryloxybutanoic acid; Benzofuran propanoic acid; Type 2 diabetes; Ultra high-throughput screening;
Diverse effects of G-protein-coupled free fatty acid receptors on the regulation of cellular functions in lung cancer cells
Keywords: GPR120; GPR40; Cell motility; Invasion; Lung cancer;
Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages
Keywords: Omega 3 polyunsaturated fatty acid; GPR120; Macrophage; Anti-inflammation; FFA4
Inhibitory effects of omega-3 fatty acids on early brain injury after subarachnoid hemorrhage in rats: Possible involvement of G protein-coupled receptor 120/β-arrestin2/TGF-β activated kinase-1 binding protein-1 signaling pathway
Keywords: COX-2; cyclooxygenase-2; DAPI; 4,6-diamino-2-phenyl indole; DHA; docosahexaenoic acid; EBI; early brain injury; EMSA; electrophoretic mobility shift assays; EPA; eicosapentaenoic acid; FJB; Fluoro-Jade B; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; G
GPR120 promotes adipogenesis through intracellular calcium and extracellular signal-regulated kinase 1/2 signal pathway
Keywords: GPR120; 3T3-L1; Adipogenesis; [Ca2+]i; ERK1/2
Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders
Keywords: FFA; free-fatty acids; FFA4; free-fatty acid receptor-4; FFA1; free-fatty acid receptor-1; PUFA; polyunsaturated fatty acids; ALA; α-linolenic acid; EPA; eicosapentaenoic acid; DHA; docosahexaenoic acid; Free-fatty acid receptor-4; GPR120; Polyunsaturate
Different roles of GPR120 and GPR40 in the acquisition of malignant properties in pancreatic cancer cells
Keywords: GPR120; GPR40; Cell motility; Invasion; Pancreatic cancer cells;
The role of G-protein-coupled receptor 120 in fatty acids sensing in chicken oral tissues
Keywords: Fatty acid; GPR120; Fat taste receptor; Chicken;
ReviewReview on emu products for use as complementary and alternative medicine
Keywords: Emu oil; PUFAs; MUFA; Inflammation; Antioxidant; Penetration enhancer; GPR120;
FFA4 receptor (GPR120): A hot target for the development of anti-diabetic therapies
Keywords: GPR120; Glucose metabolism; Lipid; Arrestin; Biased signaling;
Ca2+ signaling in taste bud cells and spontaneous preference for fat: Unresolved roles of CD36 and GPR120
Keywords: Lipids; Taste receptor cells; CD36; GPR120; Stim1; Ca2+ influx factor; Fatty acids; AA; arachidonic acid; [Ca2+]i; free intracellular calcium concentration; CaM; calmodulin; CIF; calcium influx factor; cPLA2; cytosolic phospholipase A2; GL; glossopharynge
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
Keywords: Free fatty acid receptor 4; Free fatty acid receptor 4 agonist; Free fatty acid receptor 4 antagonist; FFA4; GPR120;
Oncology/EndocrineDocosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target?
Keywords: Melanoma; Omega-3 fatty acid; Omega-3 polyunsaturated fatty acid; Docosahexaenoic acid; G protein-coupled receptor; GPR40; GPR120;
Research ArticleGPR120 on Kupffer cells mediates hepatoprotective effects of Ï3-fatty acids
Keywords: ALT; Alanine transaminase; AST; Aspartate transaminase; GPR120; G protein-coupled receptor 120; i.p.; intra-peritoneal; i.v.; intra-venous; IRI; ischemia reperfusion injury; KC; Kupffer cells; ROS; reactive oxygen species; Ï3FAs; omega-3 fatty acids; Fat
Phenotypic characterization of GPR120-expressing cells in the interstitial tissue of pancreas
Keywords: GPR120; Pancreas; CD68; CD117; CD34
Agonism with the omega-3 fatty acids α-linolenic acid and docosahexaenoic acid mediates phosphorylation of both the short and long isoforms of the human GPR120 receptor
Keywords: GPR120; Free fatty acid; G protein-coupled receptor; Receptor phosphorylation
Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis
Keywords: G-protein-coupled receptor; Free fatty acid; Insulin; FFAR1; FFAR2; FFAR3; GPR120;
Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: Comparison with human GPR120 splice variants
Keywords: GPR120; Fatty acids; Calcium signaling
Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion
Keywords: DHA; EPA; GLP-1; Hypoglycemic effect; GPR120
The regulation of adipogenesis through GPR120
Keywords: GPR120; GPR40; Adipogenesis; Long-chain fatty acids;