Keywords: Graphene oxide; Immunosensor; Cellular surface camouflage; Pancreatic islet; Granzyme B;
مقالات ISI (ترجمه نشده)
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Keywords: 5-FU; 5-fluoro-uracil; AAV; adeno-associated virus; ADAM; ADAM metallopeptidase domain; ADCC; antibody-dependent cell-mediated cytotoxicity; CCL; chemokine (C-C motif) ligand; CD; cluster of differentiation; CTLA-4; cytotoxic T-lymphocyte-associated ant
Keywords: Polymeric nanomedicines; Peptide; Cancer therapy; Therapeutic delivery; AF; aminoflavone; ANG; angiopep-2; BBB; blood brain barrier; BCECs; brain capillary endothelial cells; BP; bortezomib-pinanediol; bPEISS; bioreducible branched polyethylenimine; BPLP;
Keywords: HLA-G; human leukocyte antigen G; HLA-E; human leukocyte antigen E; PD-L1; programmed cell death 1 ligand 1; IL-10; interleukin-10; TGF-β; transforming growth factor beta; sHLA-G; soluble HLA-G; OL; oral leukoplakia; GB; granzyme B; OPL; oral precancerou
Keywords: Granzyme B; Inflammatory markers; MMP-9; Neutrophils; S100A12; Stroke;
Keywords: BDCA-2; blood dendritic cell antigen-2; CD123; interleukin-3 receptor α chain; CTL; cytotoxic CD8 T lymphocyte; DC; dendritic cell; GZMB; granzyme B; IFN; interferon; IL; interleukin; ILT7; immunoglobulin superfamily receptor immunoglobulin-like transcri
Keywords: Breast cancer; Forest therapy; NK cell activity; Perforin; Granzyme B; Adjuvant therapy;
Keywords: Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: Atopic dermatitis; laser capture microdissection; IL-34; claudins 8 and 4; immune; barrier; AD; Atopic dermatitis; CE; Cornified envelope; CLDN; Claudin; CSF-1R; Colony-stimulating factor 1 receptor; CTLA4; Cytotoxic T-lymphocyte antigen 4; DC; Dendritic
Keywords: Cancer ablation; Hepatocellular carcinoma; Orthotopic model; Nanosecond pulsed electric fields; Electroporation; Non-thermal; Apoptosis; Absence of recurrence; Granzyme B; Immunity;
Keywords: Decorin; Lumican; Fibromodulin; Toll-like receptor; Matrix metalloproteinases; 5/6-Nx; 5/6-nephrectomized Sprague-Dawley rats; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ALK; activin like kinase; ATS; hymocyte serum; BGN (Bgn)
Keywords: Apoptosis; Caspase; Granzyme B; Fas; LAK cells; Reactive oxygen intermediates; Squamous cell carcinoma cells
Keywords: Gene expression; Granzyme B; Stroke
CD8dim but not CD8bright cells positive to CD56 dominantly express KIR and are cytotoxic during visceral leishmaniasis
Keywords: Killer Cell Immunoglobulin-like Receptors; Granzyme B; CD8dimNKT cells; Leishmania donovani;
Ox40 regulates the conversion and suppressive function of double-negative regulatory T cells
Keywords: Tregs; regulatory T cells; DNT; double-negative regulatory T cells; mDCs; mature dendritic cells; KO; knockout; WT; wild type; Ox40-KO; Ox40 knockout; IL-2; interleukin 2; GM-CSF; granulocyte macrophage colony stimulating factor; CM; complete culture medi
Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease
Keywords: Sarcoidosis; CD8+ cytolytic T cells; Perforin; Granzyme B; Granulysin; CTL; cytolytic T cell; Th; T helper; LS; Löfgren's syndrome; HLA; human leukocyte antigen; BAL; bronchoalveolar lavage; PBMC; peripheral blood mononuclear cell; PBL; peripheral blood
Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine
Keywords: Tandem repeat extracellular domain of M2 (M2e5x); Virus like particles expressing flagellin (Flag VLP); Effector T cells; Granzyme B; Innate immunity;
IL-21 dependent Granzyme B production of B-cells is decreased in patients with lupus nephritis
Keywords: SLE; IL-21; Granzyme B; Lupus nephritis;
Level of Granzyme B-positive T-regulatory cells is a strong predictor biomarker of acute Graft-versus-host disease after day +30 after allo-HSCT
Keywords: Graft-versus-host disease; Biomarker; Predictor; Granzyme B; T-regulatory cells;
Granzyme B producing B-cells in renal transplant patients
Keywords: B-cells; Renal transplantation; Allograft rejection; Regulatory B-cells; Immune tolerance; CMV; Cytomegalovirus; CsA; Cyclosporine A; GrB; Granzyme B; HC; healthy controls; IL; Interleukin; RTX; renal transplant patients;
Serpinb9 is a marker of antigen cross-presenting dendritic cells
Keywords: Serpinb9; SPI6; Dendritic cell; Cross-presentation; Granzyme B; DCs;
Immunohistochemical investigations on the expression of programmed cell death ligand 1, human leukocyte antigens G and E, and granzyme B in intraoral mucoepidermoid carcinoma
Keywords: CTL; cytotoxic T lymphocytes; GB; granzyme B; HAJ/ACCG; Goiás Combat Cancer Association's Araújo Jorge Hospital; HG; high grade; HLA; human leukocyte antigen; IG; intermediate grade; LG; low grade; MEC; mucoepidermoid carcinoma; NK; Natural Killer; OS
IL-21 May Promote Granzyme B-Dependent NK/Plasmacytoid Dendritic Cell Functional Interaction in Cutaneous Lupus Erythematosus
Keywords: GrB; granzyme B; LE; lupus erythematosus; NK; natural killer; pDC; plasmacytoid DC; Th1; T helper 1; Th17; T helper 17;
Peripheral leucocytes and tissue gene expression of granzyme B/perforin system and serpinB9: Impact on inflammation and insulin resistance in coronary atherosclerosis
Keywords: Granzyme B; Perforin; Proteinase inhibitor 9; Inflammation; Insulin resistance; Atherosclerosis;
Skin-Resident Effector Memory CD8+CD28- T Cells Exhibit a Profibrotic Phenotype in Patients with Systemic Sclerosis
Keywords: dcSSc; diffuse cutaneous systemic sclerosis; GraB; granzyme B; ND; normal donor; NS; normal skin; SSc; systemic sclerosis;
Fucosylation Deficiency in Mice Leads to Colitis and Adenocarcinoma
Keywords: Signal Transduction; Metabolism; Tumorigenesis; Colon Cancer; AAL; Aleuria aurantia lectin; CRC; colorectal cancer; FITC; fluorescein isothiocyanate; FX; guanosine diphosphate-4-keto-6-deoxymannose 3,5-epimerase-4-reductase; GDP; guanosine diphosphate;
In vivo IL-4 prevents allo-antigen driven CD8+ CTL development
Keywords: Graft-vs.-host disease; T cells; IL-4; CTL; Mouse; Cytokine; BDF1; B6D2F1; B6; C57Bl/6; GrB; granzyme B; HVG; host-vs.-graft; KO; knock out; p â F1; parent-into-F1; pfp; perforin; Tfh; T follicular helper; WT; wild type;
Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model
Keywords: Medical biotechnology; Human cytolytic fusion protein; Immunotherapy; Granzyme B; Triple negative breast cancer;
NCR1 is an activating receptor expressed on a subset of canine NK cells
Keywords: NCR1/NKp46; Dog; Natural killer cell; Granzyme B
Research paperSignificant role for IRF3 in both T cell and APC effector functions during T cell responses
Keywords: IRF; Interferon Regulatory Factor; IFN; interferon; GrB; Granzyme B; ISG; Interferon stimulated gene; DCs; dendritic cells; INAM; IRF3-dependent NK-activating molecule; Eomes; Eomesodermin; Interferon Regulatory Factor-3; Interferon-γ; Interleukin-17; Gr
M2SR, a novel live single replication influenza virus vaccine, provides effective heterosubtypic protection in mice
Keywords: ADCC; antibody-dependent cellular cytotoxicity; Aichi; influenza A/Aichi/2/1968; APC; allophycocyanin; BAL; bronchoalveolar lavage; BSA; bovine serum albumin; CPE; cytopathic effect; FCS; fetal calf serum; FITC; fluorescein isothiocyanate; HAI; hemaggluti
Up-regulation of granzyme B and perforin by staphylococcal enterotoxin C2 mutant induces enhanced cytotoxicity in Hepa1-6 cells
Keywords: Staphylococcal enterotoxins; Granzyme B; Perforin; Apoptosis; Cytotoxicity;
Enhancing NK cell cytotoxicity by miR-182 in hepatocellular carcinoma
Keywords: B2m; beta-2-microglobulin; cDNA; complementary DNA; DMEM; Dulbecco's modified eagle's medium; FBS; fetal bovine serum; GzmB; granzyme B; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; IFN-γ; interferon gamma; KIRs; killer immunoglobulin recep
Granzyme B as a diagnostic marker of tuberculosis in patients with and without HIV coinfection
Keywords: CD8+ T-cell; Granzyme B; HIV-TB coinfection; Immunodiagnosis; rESAT-6; Tuberculosis;
Polymethoxylated flavones potentiate the cytolytic activity of NK leukemia cell line KHYG-1 via enhanced expression of granzyme B
Keywords: Granzyme B; KHYG-1; NK cell; Nobiletin; Polymethoxylated flavone; p38 MAPK;
Study of effect of inhaled versus oral corticosteroids on sputum granzyme B in patients with moderate persistent bronchial asthma
Keywords: Granzyme B; Corticosteroids; Bronchial asthma
Differential effects of IL-15 on the generation, maintenance and cytotoxic potential of adaptive cellular responses induced by DNA vaccination
Keywords: IL-15; Knock out; DNA vaccine; Immune response; Cytotoxic potential; HIV; GzmB; granzyme B; KO; knockout; Tcm; central memory T cells; Tem; effector memory T cells; WT; wild type;
Enhanced anti-colon cancer immune responses with modified eEF2-derived peptides
Keywords: eEF2; eukaryotic elongation factor-2; TAAs; tumor-associated antigens; PBLs; peripheral blood lymphocytes; Tg; transgenic; TCR; T cell receptor; GrB; granzyme B; CTL; cytotoxic T lymphocyte; PBMCs; peripheral blood mononuclear cells; DC; dendritic cell; D
Effects of extracellular pH and hypoxia on the function and development of antigen-specific cytotoxic T lymphocytes
Keywords: CFSE; 5-(and 6-)carboxyfluorescein diacetate succinimydylester; CTLs; cytotoxic T lymphocytes; CTM; complete T-cell medium; GrB; granzyme B; IFN-γ; interferon-γ; mAbs; monoclonal antibodies; pO2; partial pressure of oxygen; PBS; phosphate-buffered salin
Study of serum Granzyme B in heavy cigarette smokers with and without chronic obstructive pulmonary disease
Keywords: COPD; Granzyme B; Smokers
Expression, purification and anticancer analysis of GST-tagged human perforin and granzyme B proteins in human laryngeal cancer Hep-2 cells
Keywords: Perforin; Granzyme B; Expression; Purification; Apoptosis;
Cytohesin-associated scaffolding protein (CASP) is a substrate for granzyme B and ubiquitination
Keywords: NK cell; CASP; Granzyme B; Ubiquitination;
ZPDC glycoprotein (24Â kDa) induces apoptosis and enhances activity of NK cells in N-nitrosodiethylamine-injected Balb/c
Keywords: ZPDC glycoprotein (24Â kDa); Hepatocarcinogenesis; NK cells; Perforin; Granzyme B;
Trafficking phenotype and production of granzyme B by double negative B cells (IgG+IgDâCD27â) in the elderly
Keywords: B lymphocytes; Chemokine receptors; Inflamm-aging; Elderly; IL-21; Granzyme B;
The role of intrahepatic CD3Â +/CD4Â â/CD8Â â double negative T (DN T) cells in enhanced acetaminophen toxicity
Keywords: GrB; granzyme B; DN T; double negative T; APAP; acetaminophen; DILI; drug-induced liver injury; NAPQI; n-acetyl-benzoquinone imine; NK; natural killer; CTL; cytotoxic T lymphocytes; FasL; Fas ligand; Gr; granzyme; i.p; intraperitoneally; ALT; alanine tran
MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1
Keywords: miR-150; NK cells; perforin-1; NK cell cytotoxicity; post-transcriptional regulation; immunotherapy; tumor growth and metastasis; AANAT; Aralkylamine N-acetyltransferase; DMEM; Dulbecco modified Eagle medium; E/T; Effector/target; GAPDH; Glyceraldehyde-3-
HIV replication in conjunction with granzyme B production by CCR5+ memory CD4 T cells: Implications for bystander cell and tissue pathologies
Keywords: CCR5; Granzyme B; HIV replication; Enteropathy; Memory CD4 T cells; SIV pathogenesis;
Cleavage of the interchain disulfide bonds in rituximab increases its affinity for FcγRIIIA
Keywords: RTX; rituximab; S-RTX; S-sulfonated rituximab; A-RTX; reduced and then alkylated rituximab; mAb; monoclonal antibody; ADCC; antibody-dependent cellular cytotoxicity; FcγR; Fcγ receptor; KHYG-1/FcγRIIIA; KHYG-1 cells stably expressing FcγRIIIA; SDS-P
Re-evaluation of the involvement of NK cells and C-type lectin-like NK receptors in modulation of immune responses by multivalent GlcNAc-terminated oligosaccharides
Keywords: Clr; C-type lectin related protein; GlcNAc; N-acetyl-d-glucosamine; GN4P: GlcNAc4-PAMAM; N-acetyl-d-glucosamine-coated tetrabranched polyamidoamine dendrimer; GN8P: GlcNAc8-PAMAM; N-acetyl-d-glucosamine-coated octabranched polyamidoamine dendrimer; GN4P-A
Preliminary reportThe enhanced effect of lupeol on the destruction of gastric cancer cells by NK cells
Keywords: DMSO; dimethyl sulphoxide; ERK; extracellular signal-regulated kinase; FCM; Flow cytometry; GAPDH; glyceraldehydephosphate; GraB; Granzyme B; IFN-γ; interferon-gamma; rhIL-2; recombinant human interleukin-2; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl