دانلود مقالات ISI درباره Grp94 + ترجمه فارسی

پروتئین تنظیم شده با گلوکز 94 کیلو دالر باعث ایجاد فنوتیپ تهاجمی در سلول های سرطانی می شود

Glucose-regulated protein of 94 kDa contributes to the development of an aggressive phenotype in breast cancer cells

Keywords: eIF2; eukaryotic initiation factor 2; ER; endoplasmic reticulum; Grp94; glucose-regulated protein of 94 kDa; Grp78; glucose-regulated protein of 78 kDa; HIF-1α; hypoxia inducible factor-1 alpha; HRE; hypoxia response element; Hsp; heat shock protein;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

کلستروم اکسیتوسین، واکنش استرس سلولی، التهاب و نشانگرهای اتوفایگی را در ویروس های مختلف گلوتاتیون تازه متولد می شود

Colostrum oxytocin modulates cellular stress response, inflammation, and autophagy markers in newborn rat gut villi

Keywords: Enterocytes; Stress response; LC3A; GRP94; eIF2a; IκB;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

پیشرفت راهبرد های عصبی زیستی در برابر شکست پروتئازازیس: چالش های ناشی از تولید نانو

Progressing neurobiological strategies against proteostasis failure: Challenges in neurodegeneration

Keywords: AAA; ATPases associated with diverse cellular activities; 17-AAG; 17-N-allylamino-17-demethoxygeldanamycin; ABC; ATP-binding cassette; ABCE1; ATP binding cassette subfamily E member 1; AD; Alzheimer's disease; AIF; apoptosis inducing factor; Akt; Alpha se

دانلود رایگان متن کامل مقاله ISI 104 صفحه سال انتشار : 2017 سفارش ترجمه

هدف قرار دادن پاسخ شوک گرما در ترکیب با پرتودرمانی: حساسیت سلول های سرطانی به مرگ سلولی ناشی از اشعه و افزایش ایمنی بدن آنها

Targeting the heat shock response in combination with radiotherapy: Sensitizing cancer cells to irradiation-induced cell death and heating up their immunogenicity

Keywords: 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

پس از 48 ساعت سریع رعایت یک رژیم استاندارد، پاسخ التهابی را در کبد ماوس نشان می دهد

Refeeding with a standard diet after a 48-h fast elicits an inflammatory response in the mouse liver

Keywords: A20; tumor necrosis factor, alpha-induced protein 3; ALT; alanine aminotransferase; AST; aspartate aminotransferase; Atf3; activating transcription factor 3; Cxcl; chemokine (C-X-C motif) ligand; Gapdh; glyceraldehydes-3-phosphate dehydrogenase; Glut2; gl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

هدف قرار دادن سیستم ER ـ اتوفاژی در شبکه ترابکولار برای درمان گلوکوم

Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma

Keywords: Myocilin; Glaucoma; Trabecular meshwork; Grp94; Autophagy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

TSPA as a novel ATF6α translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice

Keywords: ATF6α; ER stress; Insulin resistance; TSPA; T2DM; Akt; protein kinase B; ATF6; activating transcription factor 6; CHOP; C/EBP-homologous protein; CNX; calnexin; CRT; calreticulin; CREB; cAMP response element binding protein; ER; Endoplasmic reticulum; ER

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Bicuculline Reverts the Neuroprotective Effects of Meloxicam in an Oxygen and Glucose Deprivation (OGD) Model of Organotypic Hippocampal Slice Cultures

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ATF4; activating transcription factor 4; BIC; OGD 30 min followed by 24 h of normoxic conditions, both of them in the presence of bicuculline; CA1; Cornu ammonis 1; CCD; charge-coupled device;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Quantitative proteomics and biochemical analyses reveal the role of endoplasmin in the regulation of the expression and secretion of A Disintegrin And Metalloproteinase 12

Keywords: ADAM12S; Endoplasmin (GRP94); Label-free quantification; Secretion; Spectral counting; Docking; ADAM12S; the short form of a disintegrin and metalloproteinase 12; CANX; calnexin; CPORT; Consensus Prediction Of interface Residues in Transient complexes; Dl

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The GRP94 gene of Yesso scallop (Patinopecten yessoensis): Characterization and expression regulation in response to thermal and bacterial stresses

Keywords: Patinopecten yessoensis; GRP94; Gene expression; Heat shock; Bacteria infection;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

Keywords: αMHC-Cre; α-myosin heavy chain promoter-driven Cre recombinase; BCL2L13; Bcl-2-like protein 13; CCCP; mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone; ER; endoplasmic reticulum; FKBP8; FK506-binding protein 8; GRP78; glucose-regulated p

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Osteogenesis imperfecta: new genes reveal novel mechanisms in bone dysplasia

Keywords: ADAMTS; A disintegrin and metalloprotease with thrombospondin motifs; AR-OI; autosomal recessive osteogenesis imperfecta; ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; BiP; binding immunoglobulin protein; BMDD; bone mineraliz

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

A novel mutation in PNLIP causes pancreatic triglyceride lipase deficiency through protein misfolding

Keywords: BiP; immunoglobulin binding protein; ER; endoplasmic reticulum; GRP94; glucose-regulated protein-94; IRE1; inositol-requiring enzyme 1; PNLIP; pancreatic triglyceride lipase; PNLIPRP2; pancreatic lipase related protein 2; XBP1; X-box binding protein-1; Li

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation and function of the human HSP90AA1 gene

Keywords: Hsp90; heat shock protein 90; Grp94; glucose regulated protein 94; TRAP1; tumor necrosis factor associated protein 1; MHC1; major histocompatibility complex 1; PTM; posttranslational modification; TSS; transcription start site; HSE; heat shock element; TF

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleEndoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis

Keywords: DENA; diethyl-nitrosoamine; ER; endoplasmic reticulum; HCC; hepatocellular carcinoma; grp94; Molecular chaperone; Liver cancer; gp96;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals

Keywords: Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Correlation between chemotype-dependent binding conformations of HSP90α/β and isoform selectivity-Implications for the structure-based design of HSP90α/β selective inhibitors for treating neurodegenerative diseases

Keywords: HSP90 inhibitors; Isoform selectivity; Structure-based drug design; GRP94; TRAP1; Huntington's disease; Huntingtin;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Development of radamide analogs as Grp94 inhibitors

Keywords: Hsp90; Grp94

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Characterization of the Grp94/OS-9 Chaperone–Lectin Complex

Keywords: ER, endoplasmic reticulum; ERAD, ER-associated degradation; TMP, terminally misfolded protein; MRH, mannose recognition homology; ITC, isothermal titration calorimetry; CTE, C-terminal extension; BME, β-mercaptoethanolchaperone; Hsp90; Grp94; ER-associate

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response

Keywords: ATF6; activating-transcription-factor 6; Bip/Grp78; immunoglobulin heavy-chain binding protein; Chop; C/EBP homologous protein; Grp94; glucose-regulated protein 94 kDa; eIF2α; eukaryotic initiation factor 2α; ER; endoplasmic reticulum; FFA; free fatty

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: A differential role of unfolded protein response (UPR) signaling proteins

Keywords: AMPK; 5′ adenosine monophosphate-activated protein kinase; ATF6; activated transcription factor 6; BW; body weight; CHOP/GADD153; CCAAT/-enhancer-binding protein homologous protein; CPT1; carnitine palmitoyl transferase 1; ER; endoplasmic reticulum; GLU

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Changes in vimentin, lamin A/C and mitofilin induce aberrant cell organization in fibroblasts from Fanconi anemia complementation group A (FA-A) patients

Keywords: Fanconi anemia; Oxidative stress; Cell structure; 2D-PAGE; two dimensional polyacrylamide gel electrophoresis; AML; acute myeloid leukemia; BM; bone marrow; DSBs; double strand breaks; ER; endoplasmic reticulum; GRP94; glucose response protein 94; HSC; hu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

ER stress in diffuse large B cell lymphoma: GRP94 is a possible biomarker in germinal center versus activated B-cell type

Keywords: DLBCL; UPR; GRP94

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Anti-KDEL-coated nanoparticles: A promising tumor targeting approach for ovarian cancer?

Keywords: Nanoparticle; Targeting; Ovarian cancer; GRP78; GRP94; DiO; dioctadecyloxacarbo-cyanine perchlorate; EDAC; 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimidide; ER; endoplasmic reticulum; GRP; glucose-regulated protein; HER; herceptin; mAb; monoclonal antibod

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Redox signaling loops in the unfolded protein response

Keywords: AGR2; anterior gradient 2; ARE; antioxidant responsive element; ATF4; activating transcription factor-4; ATF6; activating transcription factor-6; ASK1; apoptosis signal-regulating kinase-1; BI-1; BAX inhibitor-1; BiP; immunoglobulin heavy chain-binding pr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - Reversal by a chemical chaperone

Keywords: ABCA-1; ATP binding cassette transporter class A type I; ABCG-1; ATPbinding cassette transporter class G type I; AGE; advanced glycation end products; AGE-alb; advanced glycated albumin; Apo A-I; apolipoprotein A-I; ATF6; activating transcription factor 6

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Participation of endoplasmic reticulum stress in the pathogenesis of spontaneous glomerulosclerosis-Role of intra-renal angiotensin system

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; GS; glomerulosclerosis; AT-1; angiotensin II receptor type1; ARB; angiotensin receptor-1 blockade; GRP94; glucose-regulated protein 94; GRP78; glucose-regulated protein 78, GRP78 also known as BiP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Autoimmunity to endoplasmic reticulum chaperone GRP94 in myasthenia gravis

Keywords: Autoantibody; Autoimmune diseases; ER stress; GRP94; Immunoprecipitation; Myasthenia gravis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Hsp90b1 knockout targeted to male germline: a mouse model for globozoospermia

Keywords: Gp96; Grp94; endoplasmic reticulum; spermiogenesis; male infertility; mouse model; Vasa-Cre;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity

Keywords: BiP; binding protein (GRP78); ER; endoplasmic reticulum; ERAD; ER associated degradation; GRP94; glucose regulated protein 94; HFE; hereditary hemochromatosis protein; HLA-I; human leukocyte antigen-I; IFN-γ; interferon-γ; IL-2; interleukin-2; MHC-I; ma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Differential expression of heat shock protein genes in preconditioning for photosynthetic acclimation in water-stressed loblolly pine

Keywords: GRP94; HSP70; Promoter analysis; sHSP; HSP; Heat shock protein; BIP; Luminal binding protein; PDI; Protein disulfide isomerase; UPRE; Unfolded protein response element; STRE; Stress response element;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Stress Signaling in the Methionine-Choline-Deficient Model of Murine Fatty Liver Disease

Keywords: Steatosis; Steatohepatitis; Endoplasmic Reticulum Stress; Integrated Stress; apoB100; apolipoprotein B100; ATF6; activating transcription factor-6; Bcl-xL; B-cell lymphoma extra-large; BiP; immunoglobulin-binding protein; CHOP; C/EBP homologous protein; e

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Gp93, the Drosophila GRP94 ortholog, is required for gut epithelial homeostasis and nutrient assimilation-coupled growth control

Keywords: Drosophila; Gp93; Hsp90; GRP94; HSP90B1; Copper cell; Midgut; Epithelium; Endoderm; Growth control;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells

Keywords: ATF6; activating transcription factor 6; BiP/GRP78; immunoglobulin heavy chain-binding protein or 78 kDa glucose-regulated protein; CHOP/GADD153; C/EBP homologous protein or growth arrest- and DNA damage-inducible gene 153; eIF2α; eukaryotic translation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

cDNA cloning and expression of grp94 in the Pacific oyster Crassostrea gigas

Keywords: Crassostrea gigas; Endoplasmic reticulum (ER); GRP94; Hypoxia; Molecular chaperone; Mollusk; Oyster;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Different Poses for Ligand and Chaperone in Inhibitor-Bound Hsp90 and GRP94: Implications for Paralog-Specific Drug Design

Keywords: Gdm, geldanamycin; Rdc, radicicol; PEG, polyethylene glycol; MME, monomethyl ether; PDB, Protein Data BankHsp90; GRP94; geldanamycin; radamide; chaperone

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas

Keywords: Gastric carcinoma; GRP78; GRP94; Pathogenesis; Progression; Prognosis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Phosphorylated PKR contributes the induction of GRP94 under ER stress

Keywords: Phosphorylated PKR; ER stress; GRP94; GRP78

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Viral insertion in Evi12 causes expression of aberrant Grp94 mRNAs containing the viral gag myristylation motif

Keywords: Proviral insertion; Evi12; Grp94; Leukemia; Myristylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

A non-receptor-mediated mechanism for internalization of molecular chaperones

Keywords: gp96; grp94; Dendritic cells; Receptors; Endocytosis; Flow cytometry; Stress proteins; Heat shock proteins

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Induction of cellular stress and chaperone activation in organotypic slice cultures of hippocampus

Keywords: Hippocampus; Slice cultures; ER stress; Chaperones; GRP78/BiP; GRP94; Astrocytes; Neuroprotection;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Lithium toxicity and expression of stress-related genes or proteins in A549 cells

Keywords: Lithium; oxidative stress; Cytochrome P450; HSP; GRP94

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Mood stabilizing drug lithium increases expression of endoplasmic reticulum stress proteins in primary cultured rat cerebral cortical cells

Keywords: Lithium; Valproate; GRP78; GRP94; Calreticulin

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1

Keywords: GRP78; GRP94; E47 cells; Oxidative stress; ER stress

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Overexpression of endoplasmic reticulum molecular chaperone GRP94 and GRP78 in human lung cancer tissues and its significance

Keywords: Grp94; GRP78; Expression; Human lung cancer; Endoplasmic reticulum molecular chaperone; Differentiation; Cancer progression; RNA isolation; Immunohistochemistry; Western blot; Lung squamous carcinoma; Lung adenocarcinoma; Lung adenosquamous carcinom; Lung

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Disruption of the endoplasmic reticulum by cytotoxins in LLC-PK1 cells

Keywords: Cytotoxicity; Endoplasmic reticulum; GRP94; GRP78; Caspase-12; LLC-PK1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Dying a Thousand Deaths: Redundant Pathways From Different Organelles to Apoptosis and Necrosis

Keywords: Akt; proto-oncogene product of the viral oncogene v-akt; AIF; apoptosis inducing factor; Apaf-1; apoptotic protease activating factor-1; ATF6; activating transcription factor 6; Bad; heterodimeric partner for Bcl-xL and Bcl-2; Bak; Bcl2 homologous antagon

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Up-regulation of 94-kDa glucose-regulated protein by hypoxia-inducible factor-1 in human endothelial cells in response to hypoxia

Keywords: Hypoxia; HIF-1; Endothelial cell; GRP94; Promoter;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه