Keywords: ACC1; acetylcoenzyme A carboxylase 1; ASIP; agouti signaling protein; BETA2; transcription factor Beta 2; CYP7a1; cytochrome P450, family 7, subfamily a, polypeptide 1; cFOS; transcription factor C-fos; FASN; fatty acid synthase; FOXA2; forkhead box prote
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Beta cell line; Oxidative stress; Carnosine; Diabetes; Pancreatic islet transplantation; CI; CELL index; D-CA; D-carnosine; L-CA; L-carnosine; NAC; N-acetyl-L-cysteine; DCF-DA; 2â²,7-dichlorofluorescein-diacetate; GSIS; glucose stimulated insulin secreti
Keywords: T2DM; type 2 diabetes; GSIS; glucose-stimulated insulin secretion; SNP; single nucleotide polymorphism; KoGES; Korean Genome Epidemiology Study; KARE; Korea Association Resource; GWAS; genome-wide-association studies; Cdc42; cell division control protein
Keywords: Diabetes; Isoflavones; Insulin resistance; Phytochemicals; Pancreatic β-Cells; DM; diabetes mellitus; T1DM; Type 1 diabetes mellitus; T2DM; Type 2 diabetes mellitus; DHD; dihydrodaidzein; O-Dma; O-desmethylangolensin; DHG; dihydrogenistein; 6-OH-O-Dma; 6
Keywords: Angiopoietin-like protein 4 (Angptl4); Pancreas; Insulin secretion; Protein kinase A; Angptls; angiopoietin-like proteins; Angptl4; angiopoietin-like protein 4; cAMP; cyclic adenosine monophosphate; CCD; coiled-coil domain; DMEM; Dulbecco's modified Eagle
Keywords: 4-HDDE; 4-Hydroxy-2E,6Z-dodecadienal; 4-HHE; 4-Hydroxyl-2E-hexenal, 4-HNE, 4-Hydroxy-2E-nonenal; AGE; Advanced glycation end products; ALE; Advanced lipoxidation end products; AR; aldose reductase; COX; Cyclooxygenase; EET; Epoxyeicosatrienoic acid; ER; E
Keywords: aR'; activity coefficient ratio; CDC; complete depolarization cocktail; ÎÏM; mitochondrial membrane potential; ÎÏP; plasma membrane potential; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; GSIS; glucose-stimulated insulin secretion; KA
Keywords: Baicalin; Baicalein; Flavonoids; Chemoprevention; Inflammatory diseases; 6-OHDA; 6-hydroxydopamine; 12-LOX; 12-lipoxygenase; AIDS; acquired immunodeficiency disorder syndrome; AhR; aryl hydrocarbon receptor; AIH; autoimmune hepatitis; AICAR; 5-aminoimidaz
Keywords: Glucose tolerance; Inflammation; Insulin secretion; Insulin resistance; Nitrite; Type 2 diabetes; NO; nitric oxide; GSIS; glucose-stimulated insulin secretion; QUICKI; quantitative insulin sensitivity check index; HOMA-IR; homeostasis model assessment of
Keywords: 6PGDH; 6-phosphogluconate dehydrogenase; KATP; ATP-sensitive K+ channel; ER; endoplasmic reticulum; G6PDH; glucose-6-phosphate dehydrogenase; GC; gas chromatography; GHB; γ-hydroxybutyric acid; GSIS; glucose-stimulated insulin secretion; ICDc; cytosolic
Keywords: SM; sphingomyelin; SMS; sphingomyelin synthase; Cer; ceramide; CerS; ceramide synthase; S1P; sphingosine 1 phosphate; LC/ESI-MS/MS; liquid chromatography/electrospray ionization-tandem mass spectrometry; VLCFA; very long-chain fatty acid; HexCer; hexosylc
Keywords: AGL; Above Ground Level; MCP; Measure Correlate Predict; CNT; Centralized; MDM; Metrological Department Malaysia; CSP; Concentrating Solar Power; MMD; Malaysian Meteorological Department; DCNT; Decentralized; MHP; Micro Hydropower; DEM; Digital Elevation
Keywords: Beta cells; Diabetes; Eicosanoids; Fatty aldehyde dehydrogenase; Glutathione peroxidase; Glutathione-S-transferase4-hydroxyalkenals; 4-Hydroxynonenal; Lipid peroxidation; Phospholipase A; 12-HETE (PubChem CID: 5283155); 15-HETE (PubChem CID: 280724); 4-HN
Keywords: Suicide ideation; Meaning in life; Resiliency; Depression; GSIS; EMIL;
Keywords: Wharton's jelly; Mesenchymal stem cells; Diabetes mellitus; Insulin producing cells; Pluripotency/stem cell markers; CB-MSCs; Cord blood mesenchymal stem cells; CD; Cluster of differentiation; DM; Diabetes mellitus; DMEM; Dulbecco's modified Eagle medium;
Keywords: AGE-RAGE; advanced glycation end products; AI; atherogenic index; AMPK; AMP-activated protein kinase; Ara; arabinose; Bax; pro-apoptotic Bcl2-associated X; Bcl-2; B-cell leukaemia/lymphoma 2; BG; blood glucose; CAT; catalase; Fuc; fucose; FBG; fasting blo
Keywords: Îp; proton motive force established on inner mitochondrial membrane; ÎÏ; electrical membrane potential established on inner mitochondrial membrane; COX4.1; cytochrome c oxidase subunit 4 isoform 1; ERK; extracellular signal-regulated kinase; FA; fatty
Keywords: CNS; central nervous system; INS-1; insulin secreting β-cell line originated from a rat insulinoma; GK rat; Goto-Kakizaki rat; NOD mouse; non-obese diabetic mouse; TKP; tryptophan/kynurenine pathway; Trp; tryptophan; KYN; kynurenine; 3HK; 3-OH-kynureni
Keywords: GSIS; glucose-stimulated insulin secretion; T; testosterone; DHT; 5α-dihydrotestosterone; AR; androgen receptor; Tfam; mitochondrial transcription factor A; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; NRF1; nuclear respiratory
Keywords: AA; arachidonic acid; ALP; alkaline phosphatase; ALX; G protein-coupled lipoxin A(4) receptor; AMP; adenosine monophosphate; BAT; brown adipose tissue; BMC; bone mineral content; BMD; bone mineral density; BMI; body mass index; CKD; chronic kidney disease
Keywords: Catharanthus roseus; Catharanthus roseus (L). Don; GSIS; glucose-stimulated insulin secretion; HFD; high-fat diet; STZ; streptozotocin; OGTT; oral glucose tolerance test; HbA1c; glycated hemoglobin; TG; plasma triglyceride; TEA; tetraethylammonium chlorid
Keywords: 7,8-DHF; 7,8-dihydroxyflavone; Aβ; amyloid beta; AchE; acetylcholine-esterase; ABCA1; ATP-binding cassette transporter 1; APP; amyloid precursor protein; Akt; protein kinase B; ApoE; apolipoprotein E; AAV/Aβ; adeno-associated viral vector carrying Aβ c
Keywords: AA; arachidonic acid; COX; cyclooxygenase; EET; epoxyeicosatrienoic acid; FALDH; fatty aldehyde dehydrogenase; GLUT1; glucose transporter 1, GPx, glutathione peroxidase; GSIS; glucose-stimulated insulin secretion; 4-HDDE; 4-hydroxy-2E, 6Z-dodecadienal; HF
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; Ang-II; angiotensin II; AP-1; activator protein 1; ARIC; Atherosclerosis Risk in Communities; ATF-6; activating transcription factor-6; CAC; coronary artery calcification; CARDIA; Coronary Artery Risk Development
Discovery of a novel potent GPR40 full agonist
Keywords: GPR40 full agonist; Insulin secretagogues; Type 2 diabetes mellitus; GPCR; GSIS;
Discovery of novel benzo[b]thiophene tetrazoles as non-carboxylate GPR40 agonists
Keywords: GPR40 agonist; Tetrazole; Type 2 diabetes; GPCR; GSIS;
Lysophosphatidylcholine and its phosphorothioate analogues potentiate insulin secretion via GPR40 (FFAR1), GPR55 and GPR119 receptors in a different manner
Keywords: Lysophosphatidylcholine (LPC); GPR40 (FFAR1); GPR55; GPR119; Insulin secretion; [Ca2+]i; intracellular calcium ions concentration; cAMP; cyclic AMP; GSIS; glucose-stimulated insulin secretion; GPCR; G protein coupled receptor; IBMX; 3-isobutyl-1-methylxan
Durability of protective effect of dulaglutide on pancreatic β-cells in diabetic mice: GLP-1 receptor expression is not reduced despite long-term dulaglutide exposure
Keywords: Apoptosis; β-cell; GLP-1 receptor; Cell proliferation; Dulaglutide; Durability; Dula; Dulaglutide; GLP-1R; Glucagon-like peptide-1 receptor; GSIS; Glucose-stimulated insulin secretion; IPITT; Intraperitoneal insulin tolerance test; TG; Triglyceride; NEFA
NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations
Keywords: Human induced pluripotent stem cells; NKX6.1; Reporter cell line; Directed differentiation; hiPSC-derived beta cells; EBiSC; European Bank for Induced Pluripotent Stem Cells; FACS; Fluorescence activated cell sorting; GFP; Green fluorescence protein; GSIS
Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Keywords: Apoptosis; β cells; Inflammation; Lysine demethylases; Gene expression; Diabetes; ATF; Activating transcription factor; ChIP; Chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DP; Death promoting gene; ER; Endoplasmic reticulum; FDH; Formald
Insights into pathogenesis of five novel GCK mutations identified in Chinese MODY patients
Keywords: GCK; Glucokinase; GKRP; Glucokinase regulatory protein; GSIS; Glucose-stimulated insulin secretion; G6P; Glucose-6-phosphate; GKAs; Glucokinase activators; MODY; Maturity-onset diabetes of the young; mGCK; Mutant GCK; OHA; Oral hypoglycaemic agents; WT GC
Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control
Keywords: AAV; adeno-associated virus; DIO; diet-induced obesity; GCC; guanylyl cyclase receptor; GN; guanylin peptide; GSIS; glucose-stimulated insulin secretion; GUCA2A; guanylate cyclase activator 2A gene; GUCA2B; guanylate cyclase activator 2B gene; ISH; in sit
Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis
Keywords: ASC; Inflammation; Danger associated-molecular patterns; Potassium; Purinergic receptors; KDAC; lysine deacetylase; HDAC; histone deacetylase; HDACi/KDACi; HDAC/KDAC inhibition; NLRP; NLR (NOD-like receptor) family pyrin domain containing; NLRC; NLR Famil
Mitochondrial uncoupling, ROS generation and cardioprotection
Keywords: ANT; adenine nucleotide translocator; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CcO; cytochrome c oxidase; DNP; 2,4-dinitrophenol; FCCP; carbonyl cyanide p-trifluoromethoxyphenylhydrazone; GSIS; glucose-stimulated insulin secretion; HNE; 4-hydroxy-2
The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates
Keywords: EndoC-βH1; Pseudoislets; Glucose stimulated insulin secretion; Somatostatin signaling; Proliferation; BB; Bombesin; PACAP; Pituitary Adenylate Cyclase-Activating Polypeptides; SST; Somatostatin; Bxv1; B10 xenotropic virus 1; GLP1R; GLP1 receptor; GSIS; G
INGAP-PP effects on β-cell mass and function are related to its positive effect on islet angiogenesis and VEGFA production
Keywords: Insulin secretion; Angiogenesis; Islet cells; Diabetes; T2D; Type 2 diabetes; INGAP; islet neogenesis associated protein; GSIS; glucose stimulated insulin secretion; GTT; glucose tolerance test; AUC; area under the curve; TBARS; Thiobarbituric acid reacti
Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption
Keywords: Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR
Prolonged stimulation of insulin release from MIN6 cells causes zinc depletion and loss of β-cell markers
Keywords: Zn2+; zinc ions; MT; metallothionein; ZIP; Zrt- and Irt-related protein; ZnT; zinc transporter protein; GSIS; glucose-stimulated insulin secretion; KATP channels; ATP-sensitive potassium channels; L-VGCC; L-type voltage-gated calcium channels; Ca2+; calci
Deactivation of the NLRP3 inflammasome in infiltrating macrophages by duodenal-jejunal bypass surgery mediates improvement of beta cell function in type 2 diabetes
Keywords: ASC; apoptosis-associated speck-like protein; AUC; area under the curve; CRP; circulating C-reactive protein; CD68; Cluster of Differentiation 68; DIO; diet-induced obesity; DMEM; Dulbecco's Modified Eagle Medium; DJB; duodenal-jejunal bypass; FBS; fetal
BDE-47 and BDE-85 stimulate insulin secretion in INS-1 832/13 pancreatic β-cells through the thyroid receptor and Akt
Keywords: GSIS; glucose-stimulated insulin secretion; POP; Persistent organic pollutant; PBDE; poly-brominated diphenyl ether; BDE-47; 2,2â²,4,4â²- tetrabromodiphenyl ether; BDE-85; 2,2â²,3,4,4â²-pentabromodiphenyl ether; TR; thyroid receptor; BDE-47; BDE-85; G
Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction
Keywords: HG; high glucose; GEFs; guanine nucleotide exchange factors; GSIS; glucose-stimulated insulin secretion; NOD mice; nonobese diabetic mice; Nox2; phagocyte-like NADPH oxidase; Rac1; Ras-related C3 botulinum toxin substrate 1; ROS; reactive oxygen species;
ReviewRegulation of insulin exocytosis by calcium-dependent protein kinase C in beta cells
Keywords: Protein kinase C; Insulin; Exocytosis; Beta cell; PKC; protein kinase C; DAG; diacylglycerol; PIP2; phosphatidylinositol-4,5-bisphosphate; GSIS; glucose stimulated insulin secretion; PLC; phospholipase C; IP3; inositol triphosphate; PMA; phorbol 12-myrist
Transcribing β-cell mitochondria in health and disease
Keywords: β-Cell; Mitochondria; Islets; Genome-wide association study (GWAS); Insulin secretion; Expression quantitative trait locus (eQTL); ATGL; adipocyte triglyceride lipase; AMPK; AMP-dependent protein kinase; COX; Cytochrome c oxidase; CYTB; Cytochrome b; ERR
Transgenerational pancreatic impairment with Igf2/H19 epigenetic alteration induced by p,p'-DDE exposure in early life
Keywords: p,p'-DDE; p,p'-Dichlorodiphenoxydichloroethylene; IGT; impaired glucose tolerance; Igf2; insulin like growth factor-2; DMRs; differentially methylated regions; ICR; imprinted control regions; GSIS; glucose stimulated insulin secretion; p,p'-DDE; Tra
Mechanisms of the amplifying pathway of insulin secretion in the β cell
Keywords: ABCC8; ATP binding cassette subfamily C member 8; ADCY5; adenylyl cyclase type 5; AICAR; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; DPP-IV; dipeptidyl peptidase 4; G6PD; glucose-6-phosphate dehydrogenase; GDH; glutamate dehydrogenase; GIP; gast
Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors
Keywords: PDE10a inhibitor; Insulin secretagogues; Type 2 diabetes; GPCR; GSIS; Brain penetration;
Acute intravenous glucose load impairs early insulin secretion and insulin content in islet β cells in mice
Keywords: Acute hyperglycemia; IPGTT; GSIS; Insulin granules
Coffee silverskin extract improves glucose-stimulated insulin secretion and protects against streptozotocin-induced damage in pancreatic INS-1E beta cells
Keywords: CF; caffeine; CGA; chlorogenic acid; CSE; coffee silverskin extract; DCF; dichlorofluorescein; GPx; glutathione peroxidase; GR; glutathione reductase; GSH; reduced glutathione; GSIS; glucose-stimulated insulin secretion; KRB; Krebs-Ringer bicarbonate bu
Adaptive response of rat pancreatic β-cells to insulin resistance induced by monocrotophos: Biochemical evidence
Keywords: IGF1; insulin like growth factor 1; IR; insulin resistance; MCP; monocrotophos; OPI; organophosphorus insecticide; GSIS; glucose sensitive insulin secretion; PC; pyruvate carboxylase; mG3PDH; mitochondrial glycerol-3-phosphate dehydrogenase; MDH; malate d
GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space
Keywords: GPR40; G protein-coupled receptor 40; FFA1; free fatty acid receptor 1; PK; pharmacokinetic; GSIS; glucose-stimulated insulin secretion; T2DM; type 2 diabetes mellitus; IDF; International Diabetes Federation; GLP-1; glucagon-like peptide1; GIP; gastric in