Keywords: Skin sensitization; Allergic contact dermatitis (ACD); Adverse outcome pathway (AOP); DPRA; KeratinoSensâ¢; LuSens; h-CLAT; (modified) MUSST; Database; Integrated testing strategy (ITS);
مقالات ISI (ترجمه نشده)
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Assessment of the skin sensitisation hazard of functional polysiloxanes and silanes in the SENS-IS assay
Keywords: Skin sensitisation; Functional polysiloxanes and silanes; In chemico; In vitro; SENS-IS; DPRA; KeratinoSensâ¢; mMUSST; h-CLAT; LLNA; GPMT;
Evaluation of in vitro assays for the assessment of the skin sensitization hazard of functional polysiloxanes and silanes
Keywords: Sensitization; Polysiloxanes; Silanes; In vitro; DPRA; KeratinoSensâ¢; mMUSST; h-CLAT; LLNA; GPMT;
Comparison and validation of an in vitro skin sensitization strategy using a data set of 33 chemical references
Keywords: Ac; Acylating agents; ACD; Allergic Contact Dermatitis; AOP; Adverse Outcome Pathway; ARE; Antioxidant Response Element; DC; dendritic cell; DMSO; dimethyl sulfoxide; DNCB; dinitrochlorobenzene; DPRA; Direct Peptide Reactivity Assay; ECVAM; European Centr
Binary test battery with KeratinoSens⢠and h-CLAT as part of a bottom-up approach for skin sensitization hazard prediction
Keywords: Skin sensitization; KeratinoSensâ¢; h-CLAT; Hazard identification; Bottom-up approach;
Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?
Keywords: Adverse Outcome Pathway; Skin sensitization; Pre-hapten; Pro-hapten; DPRA; h-CLAT; KeratinoSensâ¢; Reaction mechanistic domain;
Predicting skin sensitisation using a decision tree integrated testing strategy with an in silico model and in chemico/in vitro assays
Keywords: Skin sensitisation; Derek Nexus; DPRA; KeratinoSens; LuSens; h-CLAT; U-SENS; Integrated testing strategy; In silico assessment; ACD; allergic contact dermatitis; AOP; adverse outcome pathway; CLP; classification labelling and packaging; DC; dendritic cell
Skin sensitization risk assessment model using artificial neural network analysis of data from multiple in vitro assays
Keywords: Skin sensitization; Risk assessment; SH test; h-CLAT; Antioxidant response element, ARE; Artificial neural network;
Development of an in vitro skin sensitization test based on ROS production in THP-1 cells
Keywords: BH; 1-bromohaxane; BKC; benzalkonium chloride; CB; chlorobenzene; CM-H2DCFDA; 5-(and 6-)-chloromethyl-2â², 7â²-dichlorodihydrofluorescein diacetate, acetyl ester; DCs; dendritic cells; DCV5; concentration showing 5% decrease of cell viability relative
Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals
Keywords: Skin sensitization; Cell-surface thiols; SH test; h-CLAT; Artificial neural network; Risk assessment;
Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency
Keywords: h-CLAT; human Cell Line Activation Test (h-CLAT); EC3; estimated concentration that produces a stimulation index of 3 in the murine local lymph node assay; LLNA; murine local lymph node assay; CV75; tested concentration providing a cell viability of 75%;
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: Skin sensitisation
Keywords: ACD; allergic contact dermatitis; AEL; acceptable exposure level; APC; antigen presenting cells; CEL; consumer exposure level; CIR; cosmetic ingredient review; COLIPA; the European Cosmetics Association; DC; dendritic cells; DPRA; direct peptide reactivit
Putting the parts together: Combining in vitro methods to test for skin sensitizing potentials
Keywords: ARE; antioxidant response element; AUC; area under the curve; C.C; control cells; CV75; concentration reducing viability to 75%; DC; dendritic cells; DMSO; dimethyl sulfoxide; DNCB; 1-chloro-2,4-dinitrobenzene; DPRA; Direct Peptide Reactivity Assay; ECHA;
Inter-laboratory study of the in vitro dendritic cell migration assay for identification of contact allergens
Keywords: MUTZ-LC; MUTZ-3 derived Langerhans Cells; CMC; cytokine maturation cocktail; MUSST; myeloid U937 skin sensitisation test; h-CLAT; human cell line activation test; MUTZ-3; Migration; Sensitizer; Dendritic cell; In vitro; Assay; Chemokine;
The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: Results of a ring-study in five laboratories
Keywords: LLNA; local lymph node assay; Nrf2; nuclear factor-erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; SOP; standard operating procedure; WLR; within laboratory reproducibility; BLR; between laborat