Artificial neural network analysis of data from multiple in vitro assays for prediction of skin sensitization potency of chemicals

► Combination of h-CLAT and SH test improved the accuracy of prediction of LLNA. ► SH test, CV75 value (cytotoxicity) and h-CLAT were correlated with LLNA. ► Artificial neural network model by SH test/CV75/h-CLAT was correlated with LLNA. ► SH test and the peptide-binding assay were mutually correlated.