
Activated p300 acetyltransferase activity modulates aortic valvular calcification with osteogenic transdifferentiation and downregulation of Klotho
Keywords: کلاه; ac-H3K9; histone acetylation at histone H3 Lys 9; AV; aortic valve; CAVD; calcific aortic valve disease; ECM; extracellular matrix; Egr-1; early growth response-1; ERK; extracellular signal-regulated kinase; HAT; histone acetyltransferase; HDAC; histone d