A novel orally available small molecule that inhibits hepatitis B virus expression
Keywords: RG7834; HBV; HBsAg; Viral gene expression; Humanized mice;
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Hepatitis B virus: The challenge of an ancient virus with multiple faces and a remarkable replication strategy
Keywords: Hepatitis B virus; Chronic hepatitis B; Hepadnaviridae; Vertical transmission; Viral life cycle; p22cr; 22-kDa core-related protein; anti-HBc; anti hepatitis B core protein antibodies; Alix; apoptosis linked gene II interacting protein X; ARD; arginine-ri
Novel HBV recombinants between genotypes B and C in 3â²-terminal reverse transcriptase (RT) sequences are associated with enhanced viral DNA load, higher RT point mutation rates and place of birth among Chinese patients
Keywords: AA; amino acid; ADV; adefovir-dipivoxil; ALT; alanine aminotransferase; AST; aspartate aminotransferase; C; core; CHB; chronic hepatitis B; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; NUC; nucleos(t)ide analog
Efficacy of NVR 3-778, Alone and In Combination With Pegylated Interferon, vs Entecavir In uPA/SCID Mice With Humanized Livers and HBV Infection
Keywords: CAM; ER Stress Response; Assembly Inhibitor Core Protein; Replication; DAA; ALT; alanine aminotransferase; CAM; capsid assembly modulator; cccDNA; covalently closed circular DNA; ER; endoplasmatic reticulum; ETV; entecavir; h-Alb; human albumin; HAP; hete
Deep sequencing identifies hepatitis B virus core protein signatures in chronic hepatitis B patients
Keywords: Hepatitis B virus core protein; Chronic hepatitis B; Deep sequencing; HBeAg status; Treatment response; HBV; hepatitis B virus; CHB; chronic hepatitis B; NUC; nucleos(t)ide analogues; peg-IFN; pegylated interferon; HBsAg; hepatitis B surface antigen; HBc;
Nonlytic Lymphocytes Engineered to Express Virus-Specific T-Cell Receptors Limit HBV Infection by Activating APOBEC3
Keywords: Antiviral; Immune Response; Immune Therapy; LTB; 3-D; 3-dimensional; AE-T; activated T; APOBEC3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; CAR; chimeric antigen receptor; cccDNA; covalently closed circular DNA; E:T; effector cell-to
Design, synthesis, and biological evaluation of new 1,2,3-triazolo-2â²-deoxy-2â²-fluoro- 4â²-azido nucleoside derivatives as potent anti-HBV agents
Keywords: 2â²-deoxy-2â²-β-fluoro-4â²-azido-β-d-arabinofuranosyl 1,2,3-triazole nucleoside; Anti-HBV activity; Nucleoside reverse transcriptase inhibitor (NRTI); Lamivudine-resistant HBV mutants; Viral DNA replication; HBV; hepatitis B virus; HCV; hepatitis C v
HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon
Keywords: Coinfection; Interferon-stimulated Gene; PRR; RIG-I; APOBEC; apolipoprotein B mRNA editing enzyme catalytic subunit; cccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; circDNA; circular DNA; GFP-IRF3; green fluorescent protein-interferon
Impact of universal infant hepatitis B vaccination in the US-affiliated Pacific Islands, 1985-2015
Keywords: Hepatitis B virus infection; HBV; HBsAg; Hepatitis B vaccination; Children; Pacific Islands;
Hepatitis B surface antigen on subviral particles reduces the neutralizing effect of anti-HBs antibodies on hepatitis B viral particles in vitro
Keywords: HBV; Neutralisation; Dane particles; Attachment; HBsAg;
A novel mutation in TAP1 gene leading to MHC class I deficiency: Report of two cases and review of the literature
Keywords: Anti-HBc IgG; antibody against Hepatitis B core antigen; CVID; common variable immunodeficiency; ER; endoplasmic reticulum; HBeAg; Hepatitis B envelope antigen; HBsAg; Hepatitis B surface antigen; HBV; Hepatitis B virus; HLA; human leukocyte antigen; Ig;
Minimal association of alleles of human leukocyte antigen class II gene and long-term antibody response to hepatitis B vaccine vaccinated during infancy
Keywords: anti-HBc; antibody against hepatitis B core antigen; anti-HBs; antibody against hepatitis B surface antigen; CI; confidence intervals; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HLA; human leukocyte antigen; OR; odd ratio; PCR-SSP; polyme
miR-101 suppresses HBV replication and expression by targeting FOXO1 in hepatoma carcinoma cell lines
Keywords: miR-101; FOXO1; HBV replication; HBsAg; HBeAg;
Hepatitis B vaccine alone may be enough for preventing hepatitis B virus transmission in neonates of HBsAg (+)/HBeAg (â) mothers
Keywords: HBV; hepatitis B virus; HBsAg; hepatitis B virus surface antigen; HBeAg; hepatitis B virus e antigen; HepB; hepatitis B vaccine; HBIG; hepatitis B immunoglobulin; MTCT; mother-to-child transmission; anti-HBs; antibody to hepatitis B virus surface antigen;
A novel hepatitis B virus-derived cis-acting sequence that enhances expression of transgenes delivered by plasmid vectors in eukaryote cell culture systems
Keywords: Cis-acting element; Hepatitis B virus; Promoter; HBV-Derived DT2 CAE; Protein production; Eukaryotic cell culture; CAE; cis-acting element; EGFP; enhanced green fluorescent protein; LHB; large surface Hepatitis B; HBsAg; Hepatitis B surface antigen; MIF;
The nucleotide changes within HBV core promoter/precore during the first 12Â weeks of nucleos(t)ide treatment might be associated with a better virological response
Keywords: ADV; adefovir dipivoxil; BCP; basic core promoter; CHB; chronic hepatitis B; CP; core promoter; EN II; enhancer II; HBeAg; hepatitis e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; LMV; lamivudine; Mut; mutation; NUC; nucleoside/nuc
Mutations in basal core promoter is associated with significant fibrosis in both HBeAg positive and negative treatment-naïve chronic hepatitis B
Keywords: CHB; chronic hepatitis B; BCP; basal core promoter; PC; precore; LSM; liver stiffness measurement; ALT; alanine aminotransferase; HBsAg; HBV surface antigen;
A terminal antibody method based on multiple factors that influence ELISA results for measurement of antibody affinity in clinical specimens
Keywords: anti-HBe; antibody to hepatitis B virus e antigen; anti-HBs; antibody to hepatitis B virus surface antigen; anti-HCV; antibody to hepatitis C virus; CV; coefficients of variation; ELISA; enzyme-linked immunosorbent assay; HBsAg; hepatitis B virus surface
Impact of hepatitis B vaccination on HBsAg kinetics, interferon-inducible protein 10 level and recurrence of viremia
Keywords: CccDNA; covalently closed circular DNA; CHB; chronic hepatitis B; ECLIA; Electrochemiluminescence immunoassay; ELISA; Enzyme-linked immunosorbent assay; HBsAg; HBV surface antigen; HCC; hepatocellular carcinoma; HOMA-IR; Homeostatic model assessment for i
Significant reduction in notification and seroprevalence rates of hepatitis B virus infection among the population of Zhejiang Province, China, aged between 1 and 29Â years from 2006 to 2014
Keywords: HBV; hepatitis B virus; HBsAg; hepatitis B surface antigen; anti-HBc; antibodies to hepatitis B core antigen; anti-HBs; antibodies to hepatitis B surface antigen; NNDRS; National Notifiable Disease Reporting System; HepB; hepatitis B vaccine; CI; confiden
Safety and immune response to a challenge dose of hepatitis B vaccine in healthy children primed 10Â years earlier with hexavalent vaccines in a 3, 5, 11-month schedule: An open-label, controlled, multicentre trial in Italy
Keywords: AEs; adverse events; anti-HBc; hepatitis B core antibody; anti-HBs; hepatitis B surface antigen antibody; CI; confidence interval; FAS; full analysis set; GMCR; geometric mean of individual concentration ratio; GMCs; geometric mean concentrations; HB; hep
Serological and molecular epidemiological outcomes after two decades of universal infant hepatitis B virus (HBV) vaccination in Nunavut, Canada
Keywords: Hepatitis B virus; Neonatal vaccination; Inuit; Canada; Vaccine follow-up; anti-HBc; antibody to the HBV core protein; anti-HBs; antibody to the HBV surface protein; HBsAg; HBV surface protein, HBV, hepatitis B virus; GMT; geometric mean titer; WHO; World
T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model
Keywords: OMT; oxymatrine; HBV; hepatitis B virus; ETV; entecavir; HBsAg; hepatitis B surface antigen; HBeAg; hepatitis B e antigen; HBcAg; hepatitis B core antigen; IFN-γ; interferon-γ; TNF-α; tumor necrosis factor-α; HE; hematoxylin and eosin; ALT; alanine am
Characteristics of patients with hepatitis B virus and hepatitis C virus dual infection in a Western European country: Comparison with monoinfected patients
Keywords: Epidemiology; Screening; Viral hepatitis; Ag; antigen; ALT; alanine aminotransferase; BASL; Belgian Association for the Study of the Liver; CI; confidence interval; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; HBsAg; hepa
Identification of amino acids in antigen-binding site of class II HLA proteins independently associated with hepatitis B vaccine response
Keywords: HBV; hepatitis B virus; anti-HBs; antibody to hepatitis B surface antigen; HBsAg; hepatitis B surface antigen; LD; linkage disequilibrium; PDB; Protein Data Bank; Leu26; leucine at position 26; GGPM; glycine-glycine-proline-methionine; DEAV; aspartic acid
Association of CYP2B6 gene polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a Chinese population
Keywords: TB; tuberculosis; ADR; adverse drug reaction; ATDH; Anti-TB drug-induced hepatotoxicity; DDI; drug-drug interaction; HIV; human immunodeficiency virus; NAT2; N-acetyltransferase 2; CYP; cytochrome P450; GST; glutathione S-transferase; ALT; alanine aminotr
Oral administration of synthetic selenium nanoparticles induced robust Th1 cytokine pattern after HBs antigen vaccination in mouse model
Keywords: HBV; hepatitis B virus; HBsAg; hepatitis B surface antigen; SeNPs; selenium nanoparticles; ELISA; enzyme-linked immunosorbent assay; PBS; phosphate buffered saline; CHB; chronic hepatitis B; LC; liver cirrhosis; HCC; hepatocellular carcinoma; HEPES; 4-2-h
The development of hepatocarcinoma after long-term antivirus treatment of Chinese patients with chronic hepatitis B virus infection: Incidence, long-term outcomes and predictive factors
Keywords: HBV; Hepatitis B virus; HCC; Hepatocellular carcinoma; CHB; Chronic hepatitis B; HBsAg; Hepatitis B surface antigen; HBeAg; Hepatitis B e antigen; TB; Total bilirubin; HCV; Hepatitis C virus; HIV; Human immunodeficiency virus; ETV; Entecavir; ADV; Adefovi
Delivery of immunoreactive antigen using a controllable needle-free jet injector
Keywords: Needle-free; Intradermal; HBsAg; Immunization; Jet injector; Control;
Comparison of the patterns of antibody recall responses to HIV-1 gp120 and hepatitis B surface antigen in immunized mice
Keywords: HIV-1; Envelope; HBsAg; T follicular helper cells; PD-1; Immune memory;
Major findings and recent advances in virus-like particle (VLP)-based vaccines
Keywords: VLP; virus-like particle; CCMV; cowpea chlorotic mottle virus; HBV; hepatitis B virus; PASP; pathogen associated structural pattern; BCR; B cell receptor; APC; antigen presenting cell; LN; lymph node; SCS; sub capsular sinus; DC; dendritic cell; cDC; conv
No. 342-Hepatitis B and Pregnancy
Keywords: Hepatitis B; antiviral therapy; breast-feeding; chronic hepatitis; immuno-prophylaxis; vertical transmission; viral load; pregnancy; ALT; alanine aminotransferase; anti-HBe; hepatitis B envelope antibody; anti-HBs; hepatitis B surface antibody; CHB; chron
Comparative characterization of hepatitis B virus surface antigen derived from different hepatitis B virus genotypes
Keywords: HBV; Hepatitis B Virus; HBsAg; Hepatits B Virus surface antigen; HBcAg; Hepatitis B Virus core antigen; HBeAg; Hepatitis B Virus e antigen; L/M/SHBs; large/middle/small Hepatitis B Virus surface protein; HBx; Hepatitis B Virus regulatory protein; HBV/X; H
Managing sharps injuries and other occupational exposures to HIV, HBV, and HCV in the dermatology office
Keywords: hepatitis B; hepatitis C; HIV; needlestick injuries; occupational exposures; anti-HBs; antibody to hepatitis B surface antigen; CDC; Centers for Disease Control and Prevention; HBeAg; hepatitis B e antigen; HBIG; hepatitis B immunoglobulin; HBsAg; hepatit
Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B
Keywords: HBV; Intrahepatic innate immune response; cccDNA; HBsAg;
Impaired expression and function of TLR8 in chronic HBV infection and its association with treatment responses during peg-IFN-α-2a antiviral therapy
Keywords: ALT; Alanine aminotransferase; CHB; Chronic hepatitis B; CM; Conditioned medium; CR; Complete response; HBeAg; Hepatitis B e antigen; HBsAg; Hepatitis B surface antigen; HBV; Hepatitis B virus; HC; Healthy control; ICS; Intracellular cytokines staining; I
Primary cardiac diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression in an immunocompetent Chinese elderly woman
Keywords: DLBCL; Diffuse large B-cell lymphoma; PCL; Primary cardiac lymphoma; MRI; Magnetic resonance imaging; HBsAg; Hepatitis B virus surface antigen; HIV; Human immunodeficiency virus; NHL; Non-Hodgkin lymphoma; GCB; Germinal center B-cell-like; ABC; Activated
The role of quantitative hepatitis B surface antigen revisited
Keywords: Hepatitis B; HBsAg; Pegylated interferon; Entecavir; Tenofovir; Antiviral treatment;
Risk for hepatitis B and C virus reactivation in patients with psoriasis on biologic therapies: A retrospective cohort study and systematic review of the literature
Keywords: biologic; HBcAg; hepatitis B virus; hepatitis C virus; psoriasis; reactivation; risk; HBcAb; HBV core-specific antibody; HBsAb; HBV surface-specific antibody; HBsAg; HBV surface antigen; HBV; hepatitis B virus; HCV; hepatitis C virus; IL; interleukin; OBI
Hepatitis due to Reactivation of Hepatitis B Virus in Endemic Areas Among Patients With Hepatitis C Treated With Direct-acting Antiviral Agents
Keywords: Therapy; Risk Factor; Coinfection; Prognostic Factor; CHC; chronic hepatitis C; DAA; direct-acting antiviral agent; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C v
Eradicating hepatitis B virus: The critical role of preventing perinatal transmission
Keywords: Chronic HBV infection; Eradication; Escape mutant; Hepatitis B immune globulin; Hepatitis B vaccine; Hepatitis B surface antigen; Mother-to-child transmission; Perinatal HBV infection; Prevention; HBV; hepatitis B virus; HBIG; hepatitis B immunoglobulins;
Hypomethylation of BORIS is a promising prognostic biomarker in hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; BORIS; the brother of the regulator of the imprinted site; CTCF; CCCTC-binding factor; ZF; zinc finger; MSP; methylation-specific PCR; ICR; imprinting control regions; PVTT; portal vein tumor thrombus; TNM; tumor node metast
Association between chronic hepatitis B virus infection and HLA-DP gene polymorphisms in the Turkish population
Keywords: HBV; Hepatitis B virus; SNPs; Single nucleotide polymorphisms; A/G; Adenine/Guanine; AFP; α-fetoprotein; CI; Confidence interval; GWAS; Genome-wide association studies; LC; liver cirrhosis; HLA; Human leukocyte antigen; RT-PCR; Real time polymerase chain
Serum hepatitis B core-related antigen is more accurate than hepatitis B surface antigen to identify inactive carriers, regardless of hepatitis B virus genotype
Keywords: HBcrAg; HBeAg negative chronic hepatitis B; HBsAg; HBV inactive carrier; Hepatitis B; Hepatitis B virus genotype;
What is new on HBsAg and other diagnostic markers in HBV infection?
Keywords: HBsAg; HBcrAg; HBV RNA; PEG-IFN; Nucleos(t)ide analogues; HBV infection;
Comparison of Tissue Elastography With Magnetic Resonance Imaging T2* and Serum Ferritin Quantification in Detecting Liver Iron Overload in Patients With Thalassemia Major
Keywords: LSM; IO; Hemoglobinopathy; Prognostic Factor; Monitor; Management; ANA; anti-nuclear antibody; ANOVA; analysis of variance; ASMA; anti-smooth muscle antibody; CI; confidence interval; ELISA; enzyme-linked immunosorbent assay; HBsAg; hepatitis B surface
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
Keywords: Hepatitis B; EASL guidelines; Treatment; Interferon; Entecavir; Tenofovir; TAF; HBsAg; Hepatocellular carcinoma; HBV DNA; HBV reactivation; Mother to child transmission;
Construction, expression and characterization of a fusion protein HBscFv-IFNγ in Komagatella (Pichia) pastoris X33
Keywords: AOX1; alcohol oxidase 1; BMGY; buffered minimal glycerol complex medium; BMMY; buffered minimal methanol-complex medium; BSA; bovine serum albumin; CB; Coomassie blue staining; ELISA; enzyme-linked immunosorbent assay; HBsAg; hepatitis B surface antigen;
Pregnancy favors the expansion of circulating functional follicular helper T Cells
Keywords: Bcl-6; transcription factor B cell lymphoma-6; CMV; cytomegalovirus; E2-17β; estradiol; ELISA; Enzyme-linked immunosorbent assay; GC; germinal center; HbsAg; hepatitis B superficial antigen; HBV; hepatitis B virus; HIV; Human immunodeficiency virus; IC
Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection
Keywords: Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf