Keywords: HCMV، ویروس سیتومگالوف انسان; HIV, human immunodeficiency virus; HCMV, human cytomegalovirus; MCMV, murine cytomegalovirus; HSCT, hematopoietic stem cell transplantation; TLRs, Toll-like receptors; PRR, pattern recognition receptor; PAMPs, pathogen-associated molecular pattern; poly I
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In vivo expression of human cytomegalovirus (HCMV) microRNAs during latency
Keywords: HCMV، ویروس سیتومگالوف انسان; cDNA, DNA complementary to RNA; dsDNA, double stranded DNA; EBV, Epstein–Barr virus; GB, major envelop glycoprotein gene; HCMV, human cytomegalovirus; HFF, human foreskin fibroblast cells; HIV, human immunodeficiency virus; IE, immediate early; Ig, immuno
Transcriptome altered by latent human cytomegalovirus infection on THP-1 cells using RNA-seq
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; lncRNAs, long noncoding RNAs; GO, gene ontology; MOI, multiplicity of infection; DEGs, differentially expressed genes; CNCI, Coding Noncoding Index; RPKM, reads per kilobase transcriptome per million readslncRNA; mRNA; RNA-seq
Mouse models for studies of HLA-G functions in basic science and pre-clinical research
Keywords: HCMV، ویروس سیتومگالوف انسان; APC, antigen presenting cell; DI, double transgenic mice expressing hβ2m and CD8; GFP, green fluorescence protein; HCMV, human cytomegalovirus; iNOS2, induced nitric oxide synthase 2; NFAT, nuclear factor of activated T-cells; NF-κB, nuclear factor kappa
Primary HCMV infection in pregnancy from classic data towards metabolomics: An exploratory analysis
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, Human Cytomegalovirus; GA, Gestational Age; AF, Amniotic Fluid; NMR, Nuclear Magnetic Resonance; Ig, Immunoglobulin; AI, Avidity Index; GC–MS, Gas Chromatography-Mass Spectrometry; PLS-DA, Partial Least Square Discriminant Analysis; KEGG, Kyoto Ency
NK cells and interferons
Keywords: HCMV، ویروس سیتومگالوف انسان; cDC, conventional dendritic cells; HCMV, human cytomegalovirus; IFNAR, type I interferon receptor; IFN, interferon; LCMV, Lymphocytic Choriomeningitis Virus; MCMV, murine cytomegalovirus; NK cells, Natural Killer cells; pDC, plasmacytoid dendritic cells;
Human cytomegalovirus replication supported by virus-induced activation of CCL2–CCR2 interactions
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; HIV, human immunodeficiency virus; HEL, human embryonic lung fibroblasts cells; IE, immediate early gene; TNF, tumor necrosis factor; DMEM, Dulbecco’s modified Eagle’s minimal essential mediumCytomegalovirus replication; CCL2;
Human cytomegalovirus infection induces leukotriene B4 and 5-lipoxygenase expression in human placentae and umbilical vein endothelial cells
Keywords: HCMV، ویروس سیتومگالوف انسان; Placenta; Human cytomegalovirus; Histoculture; 5-Lipoxygenase; Endothelial cells; LTB45-HETE, 5-hydroxyeicosatetraenoic acid; 5-LO, 5-lipoxygenase; HCMV, human cytomegalovirus; HUVECs, human umbilical vein endothelial cells; LTs, leukotrienes; LTB4, leuko
Preliminary exploration of HLA-A*1101-restricted human cytomegalovirus glycoprotein B-specific CD8+ T cells in allogeneic stem-cell transplant recipients
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; gB, glycoprotein B; MHC, major histocompatibility complex; HLA, human leukocyte antigen; HSCT, hematopoietic stem cell transplantation; CTLs, cytotoxic T lymphocytes; PBMCs, peripheral blood mononuclear cells; Ig, immunoglobin
Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; SCT, stem cell transplantation; GrM, granzyme M; GrB, granzyme BStem cell transplantation; Cytomegalovirus; Cytotoxic lymphocytes; Granzyme M
Over-expression of human cytomegalovirus miR-US25-2-3p downregulates eIF4A1 and inhibits HCMV replication
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; miRNA, microRNA; eIF4A1, eukaryotic translation initiation factor 4A1; MEM, modified Eagle’s medium; FBS, fetal bovine serum; MOI, multiplicity of infection; UTR, untranslated region; FFL, firefly luciferase; siRNA, small inte
Drug-induced severe adverse reaction enhanced by human herpes virus-6 reactivation
Keywords: HCMV، ویروس سیتومگالوف انسان; ADR, adverse drug reaction; DIHS, drug-induced hypersensitivity syndrome; DILI, drug-induced liver injury; DRESS, drug reaction with eosinophilia and systemic symptoms; HCMV, human cytomegalovirus; HHV, human herpes virus; HSR, hypersensitivity reactions;
The Tiers and Dimensions of Evasion of the Type I Interferon Response by Human Cytomegalovirus
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; dsDNA, double-stranded DNA; HSV, Herpes Simplex virus; HIV, human immunodeficiency virus; PRR, pattern recognition receptor; ISG, IFN-stimulated gene; NK, natural killer; MCMV, murine cytomegalovirus; IRF, IFN regulatory facto
Human cytomegalovirus US3 modulates destruction of MHC class I molecules
Keywords: HCMV، ویروس سیتومگالوف انسان; Antigen presentation; Immune modulation; HCMV US3 and US11; MHC class I molecules; Proteasome degradationCTL, cytotoxic T lymphocytes; ER, endoplasmic reticulum; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; HCMV, human cytomegalovirus; MHC, major hist
Autoreactivity of primary human immunoglobulins ancestral to hypermutated human antibodies that neutralize HCMV
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; AD-2S1, antigenic determinant 2 site 1; ANA, anti-nuclear antibody; gB, glycoprotein B; V, Ig variable regionHuman; Autoantibodies; B Cells; Repertoire development
Kinetics of transcription of infectious laryngotracheitis virus genes
Keywords: HCMV، ویروس سیتومگالوف انسان; BHV, bovine herpesvirus; CHX, cycloheximide; CyP, cyclophilin; dUTP, deoxyuracil triphosphate; DMEM, Dulbecco's modified Eagle's medium; E, early; E/L, early/late; EHV, equine herpesvirus; gDNA, genomic DNA; HCMV, human cytomegalovirus; HHV-6B, human herp
Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus
Keywords: HCMV، ویروس سیتومگالوف انسان; ds, double-stranded; CSF, cerebrospinal fluid; GCV, ganciclovir; HCMV, human cytomegalovirus; MSCSA, mass spectrometry-based comparative sequence analysis; SCT, stem cell transplantation; SNP, single nucleotide polymorphism; vGCV, valganciclovirHuman cyto
Human cytomegalovirus (HCMV) genotype populations in immunocompetent individuals during primary HCMV infection
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; gB, glycoprotein B; gH, glycoprotein H; UL10, unique long 10; ABs, antibodies; IgG, IgM, immunoglobulin G, immunoglobulin M; OD, optical densityHuman cytomegalovirus; Genotyping; Primary infection; DNAemia
Comparative evaluation of eight commercial human cytomegalovirus IgG avidity assays
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; ELISA, enzyme-linked immunosorbent assay; AUC, area under curve; AI, avidity indexHCMV; IgG avidity; Kits; Comparison
ER quality control in the biogenesis of MHC class I molecules
Keywords: HCMV، ویروس سیتومگالوف انسان; Cnx, calnexin; Crt, calreticulin; CST, castanospermine; ER, endoplasmic reticulum; ERAD, ER associated degradation; β2m, β2-microglobulin; HC, heavy chain; HCMV, human cytomegalovirus; PDI, protein disulfide isomerase; PLC, peptide loading complex; TAP, t
Variability and recombination of clinical human cytomegalovirus strains from transplantation recipients
Keywords: HCMV، ویروس سیتومگالوف انسان; BAL, bronchoalveolar lavage; D, donor; HCMV, human cytomegalovirus; HSV, herpes simplex virus; LIR-1, leukocyte inhibitory receptor-1; MHC, major histocompatibility complex; NK, natural killer; R, recipient; WB, whole bloodHCMV; Variability; Recombination
Prolonged endoplasmic reticulum stress promotes mislocalization of immunoglobulins to the cytoplasm
Keywords: HCMV، ویروس سیتومگالوف انسان; ASCs, antibody secreting cells; ATF6, activating transcription factor 6; ER, endoplasmic reticulum; ERAD, ER-associated degradation; GS, glycosylation site; HCMV, human cytomegalovirus; IP, immunoprecipitation; IRE-1, inositol requiring enzyme 1; PERK, PK
TRAM1 is involved in disposal of ER membrane degradation substrates
Keywords: HCMV، ویروس سیتومگالوف انسان; ATF6, activating transcription factor 6; Cln6, ceroid-lipofuscinosis neuronal protein 6; eIF2α, alpha subunit of eukaryotic initiation factor 2; ER, endoplasmic reticulum; ERAD, ER-associated degradation; HCMV, human cytomegalovirus; MHC, major histocompa
Different expression of human herpesvirus-6 (HHV-6) load in whole blood may have a significant impact on the diagnosis of active infection
Keywords: HCMV، ویروس سیتومگالوف انسان; HHV-6, Human herpesvirus-6; Gec, Genomic equivalent copies; PMNLs, Polymorphonuclear leukocytes; HCMV, Human cytomegalovirus; SCTR, Stem cell transplant recipientHuman herpesvirus-6; HHV-6; Viral load; Whole blood; Polymorphonuclear leukocytes
Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; MeCP2, Methyl CpG binding protein 2; HDAC, histone deacetylase; MIEP/E, major immediate early promoter-enhancer; NFκ-B, Nuclear factor κ-B; CREB, cAMP response element binding protein; ERF, Ets2 repressor factor; EGFP, enhance
Sensitivity of human herpesvirus 6 and other human herpesviruses to the broad-spectrum antiinfective drug artesunate
Keywords: HCMV، ویروس سیتومگالوف انسان; ART, artesunate; DMSO, dimethyl sulfoxide; EBV, Epstein–Barr virus; FCS, fetal calf serum; GCV, ganciclovir; HCMV, human cytomegalovirus; HFFs, human foreskin fibroblasts; HHV-6, human herpesvirus 6; HHV-6A/B, human herpesvirus 6 variant A/B; HSV-1, herpe
Novel vectors for simultaneous high-level dual protein expression in vertebrate and insect cells by recombinant baculoviruses
Keywords: HCMV، ویروس سیتومگالوف انسان; AcMNPV, Autographa californica multicapsid nucleopolyhedrovirus; GFP, green fluorescent protein; HCMV, human cytomegalovirus; kbp, kilo base pairs; MCMV, murine cytomegalovirus; MOI, multiplicity of infection; ORF, open reading frame; PHCMVie, human cytom
HCMV infection of PDCs deviates the NK cell response into cytokine-producing cells unable to perform cytotoxicity
Keywords: HCMV، ویروس سیتومگالوف انسان; Cell activation; Dendritic cells; Natural killer cells; Viral infectionPDC, plasmacytoid dendritic cell; HCMV, human cytomegalovirus; MOI, multiplicity of infection; MDC, myeloid dendritic cell; MoDC, monocyte-derived dendritic cell; MDM, monocyte-derived
Conserved herpesvirus protein kinases
Keywords: HCMV، ویروس سیتومگالوف انسان; CHPK, conserved herpesviral protein kinase; HSV, herpes simplex virus; VZV, varicella-zoster virus; HCMV, human cytomegalovirus; EBV, Epstein–Barr virus; KSHV, Kaposi sarcoma associated virus; HHV, human herpesvirus; AIDS, acquired immunodeficiency syndro
High prevalence of an active human cytomegalovirus infection in patients with colonic diverticulitis
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; IBD, inflammatory bowel disease; IL-6, interleukin 6; IFN, interferon; TNF, tumor necrosis factorDiverticulitis; Perforated diverticulitis; HCMV
Physical and intellectual development in children with asymptomatic congenital cytomegalovirus infection: A longitudinal cohort study in Qinba mountain area, China
Keywords: HCMV، ویروس سیتومگالوف انسان; CMV, cytomegalovirus; HCMV, human cytomegalovirus; MCMV, murine cytomegalovirus; DQ, development quotient; IQ, intelligence quotient; WPPSI, Wechsler Preschool and Primary Scale of Intelligence; SNHL, sensorineural hearing loss; CNS, central neural system
Substrate Modulation of Enzyme Activity in the Herpesvirus Protease Family
Keywords: HCMV، ویروس سیتومگالوف انسان; KSHV, Kaposi's sarcoma herpesvirus; HCMV, human cytomegalovirus; EBV, Epstein-Barr virus; DFP, diisopropyl fluorophosphonate; R, release; M, maturationallostery; induced fit; viral protease; protein-protein interactions; X-ray structure
l-Nucleoside enantiomers as antivirals drugs: A mini-review
Keywords: HCMV، ویروس سیتومگالوف انسان; HIV, human immunodeficiency virus; HBV, hepatitis B virus; HCV, hepatitis C virus; HSV, herpes simplex virus; HCMV, human cytomegalovirus; EBV, Epstein-Barr virus; VZV, Varicella-Zoster virus; RSV, respiratory syncitial virusl-Nucleoside enantiomers; Anti
RIVETS: The recombinant immunoglobulin and viral epitope tag system
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; AD-2S1, antigenic determinant 2 site 1; gB, glycoprotein BRecombinant immunoglobulin; Epitope tag; Constant region; Immunoassays
Intracellular Trafficking of the HCMV Immunoevasin UL16 Depends on Elements Present in both its Cytoplasmic and Transmembrane Domains
Keywords: HCMV، ویروس سیتومگالوف انسان; HCMV, human cytomegalovirus; ER, endoplasmic reticulum; TGN, Trans-Golgi Network; CYT,TMD, cytoplasmic and transmembrane domains,respectively; BFA, brefeldin Aintracellular trafficking; HCMV; NKG2D; TGN; transmembrane domain
A novel strategy to identify the regulatory DNA-organized cooperations among transcription factors
Keywords: HCMV، ویروس سیتومگالوف انسان; hCMV, human cytomegalovirus; MIEP, major immediate-early enhancer/promoter; ODN, oligodeoxynucleotides; ID, increment of diversityStrategy; Cooperation; Comprehensive perturbation; Transcription factor; MIEP