دانلود مقالات ISI درباره HDAC، هیستون دیازتیلاز + ترجمه فارسی

HDAC inhibitors TSA and sodium butyrate enhanced the human IL-5 expression by altering histone acetylation status at its promoter region

Keywords: HDAC، هیستون دیازتیلاز; IL-5, interleukin-5; HDAC, histone deacetylase; HAT, histone acetyltransferase; HDACi, HDAC inhibitor; TSA, trichostatin; NaBu, sodium butyrate; FACS, fluorescence-activated cell sorter; RE, responsive elementIL-5; HDACs; HDAC inhibitors; Histone hyperace

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

Keywords: HDAC، هیستون دیازتیلاز; HDAC inhibitors; microglial apoptosis; neuroprotectionDA, dopaminergic; DAPI, 4′-6-diamidino-2-phenylindole; ELISA, enzyme-linked immunosorbent assay; FITC, fluorescein isothiocyanate; HDAC, histone deacetylase; HDACIs, histone deacetylase inhibitors; LPS

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of protein kinase D activity in adult myocardium: Novel counter-regulatory roles for protein kinase Cε and protein kinase A

Keywords: HDAC، هیستون دیازتیلاز; AR, adrenergic receptor; ARVM, adult rat ventricular myocytes; cTnI, cardiac troponin I; DAG, diacylglycerol; DMSO, dimethylsulfoxide; DN, dominant-negative; ET1, endothelin-1; GRK, G protein-coupled receptor kinase; HDAC, histone deacetylase; ISO, isopre

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Kruppel-like Factors (KLFs) in muscle biology

Keywords: HDAC، هیستون دیازتیلاز; KLF, Kruppel-like Factor; PDGF, platelet derived growth factor; TGFβ, transforming growth factor β; MEF, myocyte enhancer factor; HDAC, histone deacetylase; MALDI-TOF, matrix-assisted laser desorption ionization/time-of-flightKLF; Kruppel; Cardiomyocyte;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Contribution of reactivated RUNX3 to inhibition of gastric cancer cell growth following suberoylanilide hydroxamic acid (vorinostat) treatment

Keywords: HDAC، هیستون دیازتیلاز; SAHA, suberoylanilide hydroxamic acid; HDAC, histone deacetylase; HAT, histone acetylase; TSA, trichostatin A; ChIP, chromatin immunoprecipitation; MBD, methyl-CpG binding domain; DNMT, DNA methyltransferase; 5-aza-CdR, 5-aza-2′-deoxycytidineVorinostat; R

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Drug targeting of dysregulated transcription in Huntington's disease

Keywords: HDAC، هیستون دیازتیلاز; HD, Huntington's Disease; Htt, Huntingtin; IND, Investigational New Drug; HAT, Histone Acetyl Transferase; HDAC, Histone deacetylase; SAHA, Suberoylanilide hydroxamic acid; Sir2, Silent Information Regulator (Sirtuin); SirT1, Sirtuin 1; SirT2, Sirtuin 2;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Histone Hyperacetylation in the Coding Region of Chromatin Undergoing Transcription in SV40 Minichromosomes Is a Dynamic Process Regulated Directly by the Presence of RNA Polymerase II

Keywords: HDAC، هیستون دیازتیلاز; HAT, histone acetyl transferase; HDAC, histone deacetylase; RNAPII, RNA polymerase II; ChIP, chromatin immunoprecipitation; ReChIP, Re chromatin immunoprecipitation; ISF, immune selection and fragmentation; ISFIP, immune selection fragmentation and immuno

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Small molecules affecting transcription in Friedreich ataxia

Keywords: HDAC، هیستون دیازتیلاز; Frataxin; Friedreich ataxia; Transcription; Polyamides; Histone deacetylase inhibitorFRDA, Friedreich ataxia; FXN, frataxin gene; HDAC, histone deacetylase

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Mammalian Sir2-related protein (SIRT) 2–mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation

Keywords: HDAC، هیستون دیازتیلاز; cerebellar granule cells; NAD; nicotinamide; colchicine; sirtuin; developmentBSA, bovine serum albumin; DIV, days in vitro; FCS, fetal calf serum; GFP, green fluorescent protein; HDAC, histone deacetylase; HEK293T, human embryonic kidney 293T; HRP, horser

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Sulforaphane as a promising molecule for fighting cancer

Keywords: HDAC، هیستون دیازتیلاز; CYP, cytochrome P450; GLS, glucosinolates; GST, glutathione S transferase; HDAC, histone deacetylase; ITCs, isothiocyanates; MN, micronucleus; NQO1, NAD(P)H:quinone oxidoreductase 1; PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine; SFN, sulforaphane

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Carboxyl Terminus of NKX2.5 Impairs its Interaction with p300

Keywords: HDAC، هیستون دیازتیلاز; ANF, atrial natriuretic factor; HAT, histone acetyltransferase; GST, glutathione-S-transferase; SRF, serum response factor; C/H3, cysteine/histidine-rich region; HDAC, histone deacetylase; EMSA, electrophoretic mobility-shift assayNkx2.5; inhibitory C-ter

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation

Keywords: HDAC، هیستون دیازتیلاز; HAT, histone acetyltransferase; HDAC, histone deacetylase; SER, sensitizer enhancement ratioATM; Anacardic acid; Tip60; HAT; Radiosensitivity; DNA repair

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Immunohistochemical analysis of histone H3 acetylation and methylation—Evidence for altered epigenetic signaling following traumatic brain injury in immature rats

Keywords: HDAC، هیستون دیازتیلاز; PTMs, posttranslational modifications; HDAC, histone deacetylase; CCI, controlled cortical impactDisorders of the nervous system, TraumaEpigenetic; Hippocampus; Pediatric; Posttranslational modification; Acetylation; Methylation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Human B-ind1 gene promoter: Cloning and regulation by histone deacetylase inhibitors

Keywords: HDAC، هیستون دیازتیلاز; TBP, TATA-binding protein; TAF, TBP-associated factor; TF, transcription factor; TSA, Trichostatin A; NaB, sodium butyrate; HDAC, histone deacetylase; HDI, histone deacetylase inhibitorSodium butyrate; TSA; Transfection; Luciferase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Chromatin structure and epigenetics

Keywords: HDAC، هیستون دیازتیلاز; APL, acute promyelocytic leukemias; DNMT, DNA methyltransferase; HAT, histone acetyltransferase; HDAC, histone deacetylase; HMTs, histone methyltransferases; MBDs, methyl-binding proteins; PML, promyelocytic leukemia gene; RAR, retinoic acid receptorChrom

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Leucine zipper-like domain is required for tumor suppressor ING2-mediated nucleotide excision repair and apoptosis

Keywords: HDAC، هیستون دیازتیلاز; HAT, histone acetyltransferase; HDAC, histone deacetylase; LZL, leucine zipper-like; NER, nucleotide excision repair; PCNA, proliferating cell nuclear antigen; PCR, potential chromatin regulatory; PHD, plant homeodomain; PIP, PCNA-interacting protein; wt,

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

The X-linked methyl binding protein gene Kaiso is highly expressed in brain but is not mutated in Rett syndrome patients

Keywords: HDAC، هیستون دیازتیلاز; RTT, Rett; MECP2, methyl-CpG-binding protein 2; MBD, methyl binding domain; CDKL5, cyclin-dependent kinase-like 5; PCR, polymerase chain reaction; HDAC, histone deacetylase; DPR, deletion prone region; BTB/POZ, broad complex-tramtrack-bric a brac/Poxvirus

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Epigenetic regulation of nuclear steroid receptors

Keywords: HDAC، هیستون دیازتیلاز; NR, nuclear receptor; AR, androgen receptor; ERα, estrogen receptor; PPARγ, peroxisome proliferator-activated receptor γ; HAT, histone acetyltransferase; HDAC, histone deacetylase; SRC, steroid receptor coactivator; N-CoR, nuclear receptor corepresssor; S

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

NF-κB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells

Keywords: HDAC، هیستون دیازتیلاز; Trichostatin A; Apoptosis; NF-κB; Human tongue carcinomaTSA, Trichostatin A; HDAC, histone deacetylase; NF-κB, nuclear factor-κB; HAT, histone acetyltransferase; SAHA, suberoylanilide hydroxamic acid; NaB, sodium butyrate; IκB, inhibitors of NF-κB; TNF-α,

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Connexins and their channels in cell growth and cell death

Keywords: HDAC، هیستون دیازتیلاز; cADPr, cylic ADP-ribose; Cx, connexin; CxRE, connexin response element; DNMT, DNA methyltransferase; GCV, ganciclovir; GJIC, gap junctional intercellular communication; HDAC, histone deacetylase; HSV-tk, herpes simplex virus thymidine kinase; UTR, untrans

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of the pro-inflammatory signaling induced by protein acetylation in microglia

Keywords: HDAC، هیستون دیازتیلاز; CAPE, caffeic acid phenethyl ester; Dexa, dexamethasone; EMSA, electrophoretic mobility shift assay; FBS, fetal bovine serum; HDAC, histone deacetylase; IKK2, I kappa B kinase 2 (IKK beta); IL-6, interleukin-6; JNK, c-Jun N-terminal kinase; LDH, lactate d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

The major histocompatibility complex class II transactivator is differentially regulated by interferon-γ and transforming growth factor-β in microglial cells

Keywords: HDAC، هیستون دیازتیلاز; cDNA, copy DNA; EAE, experimental allergic encephalomyelitis; MHC II, major histocompatibility complex class II; CIITA, MHC class II transactivator; HAT, histone acetyltransferase; HDAC, histone deacetylase; IFN-γ, interferon-γ; IRF-1, interferon regulato

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Role of estrogen receptor α transcriptional coregulators in tamoxifen resistance in breast cancer

Keywords: HDAC، هیستون دیازتیلاز; ERE, estrogen-response element; HAT, histone acetyltransferase; AF1, activation function 1; HDAC, histone deacetylase; Genes: ERα/β, estrogen receptor α/β; SRC1/2/3, steroid receptor coactivator 1/2/3; NCOA1/2, nuclear receptor coactivator 1/2; TIF2, tran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of the prepronociceptin gene and its effect on neuronal differentiation

Keywords: HDAC، هیستون دیازتیلاز; ppN/OFQ, prepronociceptin; cAMP, 3′–5′cyclic adenosine monophosphate; ChIP, chromatin immunoprecipitation; HDAC, histone deacetylase; CREB, cAMP-response element binding proteinNociceptin/orphanin FQ; Neuroblastoma; CREB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Carbonyl- and sulfur-containing analogs of suberoylanilide hydroxamic acid: Potent inhibition of histone deacetylases

Keywords: HDAC، هیستون دیازتیلاز; HDAC, histone deacetylase; SAHA, suberoylanilide hydroxamic acid; HAT, histone acetyltransferase; ACE, angiotensin-converting enzyme; IFN, interferon; ISG, IFN-stimulated gene; TSA, trichostatin AHistone deacetylase; Inhibitors; α-Mercaptoketone; Suberoyl

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

B29 Gene Silencing in Pituitary Cells Is Regulated by Its 3′ Enhancer

Keywords: HDAC، هیستون دیازتیلاز; GH, growth hormone; EMSA, electrophoretic mobility shift assay; DHS, DNase 1 hypersensitive site; TSA, trichostatin-A; 5-aza, 5-aza-2-deoxycytidine; HDAC, histone deacetylase; ChIP, chromatin immunoprecipitationB29 (Igβ, CD79b); Bob1 (OCA-B, OBF-1); DNA m

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Retinoic acids and trichostatin A (TSA), a histone deacetylase inhibitor, induce human pyruvate dehydrogenase kinase 4 (PDK4) gene expression

Keywords: HDAC، هیستون دیازتیلاز; PDK4, pyruvate dehydrogenase kinase 4; RA, retinoic acid; TSA, trichostatin A; HDAC, histone deacetylase; HAT, histone acetyltransferase; RXRα, retinoid X receptor α; RARα, retinoic acid receptor α; CBF, CCAAT box binding factor; RARE, retinoic acid respo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components

Keywords: HDAC، هیستون دیازتیلاز; miRNA, microRNA; miR, microRNA; TLRs, toll-like receptors; CIITA, MHC class II transactivator; UTR, untranslated region; ARE, AU-rich element; GO, gene ontology; HAT, histone acetyltransferase; HDAC, histone deacetylase; Luc, luciferaseImmune genes; Micro

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Peroxisome proliferator-activated receptor α expression is regulated by estrogen receptor α and modulates the response of MCF-7 cells to sodium butyrate

Keywords: HDAC، هیستون دیازتیلاز; DMEM, Dulbecco's Modified Eagle's Medium; DOX, doxycycline; ER, estrogen receptor; ERE, estrogen response element; FBS, fetal bovine serum; HDAC, histone deacetylase; PPAR, peroxisome proliferator-activated receptor; PPRE, peroxisome proliferator response

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Signal integration between IFNγ and TLR signalling pathways in macrophages

Keywords: HDAC، هیستون دیازتیلاز; CpG DNA; Endotoxin tolerance; Interferon; Lipopolysaccharide; Nitric oxide; STAT1; Toll-like receptorBMM, bone marrow-derived macrophage; CSF-1, colony-stimulating factor-1; HDAC, histone deacetylase; ICSBP, interferon consensus sequence binding protein;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

SULF1 Inhibits Tumor Growth and Potentiates the Effects of Histone Deacetylase Inhibitors in Hepatocellular Carcinoma

Keywords: HDAC، هیستون دیازتیلاز; DAPI, 4′,6-diamidino-2-phenylindole dihydrochloride; HAT, histone acetyltransferase; HCC, hepatocellular carcinoma; HDAC, histone deacetylase; SAHA, suberoylanilide hydroxamic acid; SULF1, sulfatase 1 enzyme; TSA, trichostatin A; TV, tumor volume

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2006 سفارش ترجمه

Sp1 elements in SULT2B1b promoter and 5′-untranslated region of mRNA: Sp1/Sp2 induction and augmentation by histone deacetylase inhibition

Keywords: HDAC، هیستون دیازتیلاز; SULT, Sulfotransferase; nt, nucleotide; TSS, transcription start site; UTR, untranslated region; RT, reverse transcription; EMSA, electrophoresis mobility shift assay; HDAC, histone deacetylase; TSA, trichostatin ASulfonation; SULT2B1 promoter; Cis-elemen

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه