دانلود مقالات ISI درباره Hdac + ترجمه فارسی

Biophenols: Enzymes (β-secretase, Cholinesterases, histone deacetylase and tyrosinase) inhibitors from olive (Olea europaea L.)

Keywords: Olive biophenols; BACE-1; AChE & BChE; HDAC; SH-SY5Y cells; Verbascoside; Rutin; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Resistance to EGFR inhibitors in non-small cell lung cancer: Clinical management and future perspectives

Keywords: NNSCLC; non-small cell lung cancer; OS; overall survival; EGFR; epidermal growth factor receptor; TKI; tyrosine kinase inhibitor; ALK; Anaplastic lymphoma kinase; MET; mesenchymal epithelial transition factor; PFS; progression free survival; HER2; human e

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD

Keywords: airway inflammation; airway remodeling; COPD; HDAC2; IL-17A; CS; cigarette smoke; CSE; cigarette smoke extract; CXCL; chemokine (C-X-C motif) ligand; ECM; extracellular matrix; HBE; human bronchial epithelial; HDAC; histone deacetylase; HRCT; high-resolut

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

NF-κB pathways in the development and progression of colorectal cancer

Keywords: 5-FU; 5-fluorouracil; AMPK/mTOR; AMP-activated Protein Kinase/mammalian target of rapamycin; APC; adenomatous polyposis coli; BAFF; B-cell activating factor; COX-2; cyclooxygenase 2; CRC; Colorectal cancer; DD; Dimerization domain; EGFR; epidermal growth

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Mechanisms controlling the anti-neoplastic functions of FoxO proteins

Keywords: ATM; ataxia telangiectasia mutated; cHL; classical hodgkin lymphoma; CML; chronic myelogenous leukemia; CSC; cancer stem cell; ERK; the extracellular signal-regulated kinase; ERα; the nuclear receptor estrogen receptor α; FoxO; forkhead box O; G6PC; glu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Epigenetic mechanisms regulating T-cell responses

Keywords: Epigenetics; gene regulation; enhancer; promoter; chromatin accessibility; histone modifications; DNA methylation; transcription factor binding; T-cell development; T-cell function; T-cell exhaustion; regulatory T cells; tissue specificity; ATAC; Assay fo

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

Keywords: NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC11 is a regulator of diverse immune functions

Keywords: APC; antigen presenting cell; CTCL; cutaneous T-cell lymphoma; DAMP; Damage associated molecular pattern; DC; dendritic cell; FDA; U.S. Food and Drug Administration; GVHD; graft versus host disease; HAT; histone acetyltransferase; HDAC; histone deacetylas

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

Epithelial mesenchymal transition Transcription Factor (TF): The structure, function and microRNA feedback loop

Keywords: SNAIL; Snail family transcriptional repressor; ZEB; Zinc finger E-box binding homeobox; BMP1; Bone Morphogenetic protein1; TWIST; twist family bHLH transcription factor 1; GSC; goosecoid hemeobox; TGF-β; transforming growth factor beta; NPC; nasopharynge

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2018 سفارش ترجمه

Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration

Keywords: HAT; histone-acetyltransferase; Gcn5; General Control Nonderepressible; HDAC; histone deacetylase; CPTH2; cyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl)hydrazone; Ubp8; ubiquitin protease 8; DUB; deubiquitylation; Psh1; E3-ubiquitin ligase; Ub; ubiq

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma

Keywords: Glioblastoma; Nanoparticle; HDAC; Quisinostat (JNJ-26481585); PLA-PEG; pH;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC inhibitors as epigenetic regulators for cancer immunotherapy

Keywords: AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

Keywords: Histone deacetylase; HDAC; Histone deacetylase inhibitor; HDACi; Tetrahydro-β-carboline; Histone deacetylase 6 inhibition assay;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Endocrine and physiological regulation of neutral fat storage in Drosophila

Keywords: Lipid metabolism; Drosophila; Obesity; Insulin; TOR; Ecdysone; AGPAT; acylglycerol-3-phosphate acyltransferase; AKH; adipokinetic hormone; BMM; Brummer; CC; corpora cardiac; DAG; diacylglycerol; Dilp; Drosophila insulin-like peptide; DGAT; diacylglycerol

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Stimulation of liver IGF-1 expression promotes peak bone mass achievement in growing rats: a study with pomegranate seed oil

Keywords: PSO; pomegranate seed oil; PBM; peak bone mass; BMD; bone mineral density; HDAC; histones deacetylases; IGF-1; insulin growth factor-1; IRS; insulin receptor substrate; MAPK; mitogen-activated protein kinase; ERK; extracellular signal-regulated kinase; CH

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Phosphorylated SIRT1 as a biomarker of relapse and response to treatment with glatiramer acetate in multiple sclerosis

Keywords: SIRT1; PBMCs; Multiple sclerosis; Histone trimethylation; Glatiramer acetate; Biomarker; AUC; area under the curve; CNS; central nervous system; CPT; cell preparation tubes; EAE; experimental autoimmune encephalomyelitis; EDSS; expanded disability status

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis

Keywords: ASC; Inflammation; Danger associated-molecular patterns; Potassium; Purinergic receptors; KDAC; lysine deacetylase; HDAC; histone deacetylase; HDACi/KDACi; HDAC/KDAC inhibition; NLRP; NLR (NOD-like receptor) family pyrin domain containing; NLRC; NLR Famil

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies

Keywords: Antitumor agents; Bioinformatics; Drug design; Enzyme inhibitors; Epigenetics; HDAC;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis, and biological evaluation of novel amide and hydrazide based thioether analogs targeting Histone deacteylase (HDAC) enzymes

Keywords: Acrylamide; Hydrazide; Thioether; HDAC; Scaffold hopping;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1

Keywords: Angiotensin II; Vascular smooth muscle cell (VSMC); Sphingosine-1-phosphate receptor (S1PR); APE/Ref-1; Vascular neointima; DCF-DA; 6-carboxy-2′,7′-dichlorofluoroscein diacetate; Ang II; angiotensin II; AT; Ang II receptor; APE/Ref-1; apurinic/apyrimi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Chromatin organization regulated by EZH2-mediated H3K27me3 is required for OPN-induced migration of bone marrow-derived mesenchymal stem cells

Keywords: Osteopontin; Bone marrow-derived mesenchymal stem cells (BMSCs); Migration; Chromatin; Nuclear mechanics; ERK1/2 signalling; AFM; atomic force microscopy; BMSCs; bone marrow-derived mesenchymal stem cells; BSA; bovine serum albumin; CSK buffer; cytoskelet

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Disruption of Epithelial HDAC3 in Intestine Prevents Diet-Induced Obesity in Mice

Keywords: Epigenetics; Gene Regulation; Mouse Model; Overweight; ChIP; chromatin immunoprecipitation; HDAC; histone deacetylase; HFD; high-fat diet; IEC; intestinal epithelial cell; RNA-seq; RNA sequencing; SCFA; short-chain fatty acid;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

SAHA and cisplatin sensitize gastric cancer cells to doxorubicin by induction of DNA damage, apoptosis and perturbation of AMPK-mTOR signalling

Keywords: SAHA; Suberoylanilide hydroxamic acid; AMPK; AMP-dependent protein kinase; HDAC; histone deacetylase; HDACi; Histone deacetylase inhibitor; mTOR; Mechanistic target of rapamycin; NHEJ; Non-homologous end joining; TSA; Trichostatin A; H3K36; Histone H3 lys

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

RNA seq analysis of a novel fish pathogenic fungus, Fusarium oxysporum: In quest of unveiling the virulence factors associated with fish infection

Keywords: GO; gene ontology; FOSC; Fusarium oxysporum species complex; MF; molecular function; CC; cellular component; BP; biological process; CBD; cellulose binding domains; CBM; carbohydrate binding modules; GH; glycoside hydrolases; SAP; secreted aspartic protea

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Beta-hydroxybutyrate Promotes the Expression of BDNF in Hippocampal Neurons under Adequate Glucose Supply

Keywords: BDNF; brain-derived neurotrophic factor; BHBA; β-hydroxybutyrate; CREB; cAMP response element binding protein; DMEM; Dulbecco's Modified Eagle's Medium; GPR; G-protein-coupled receptor; HAT; histone acetyltransferase activity (HAT); HDAC; histone dea

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Overexpression of OCT4 induced by modulation of histone marks plays crucial role in breast cancer progression

Keywords: CSC; cancer stem cell; ChIP; chromatin immunoprecipitation; DZNeP; deazaneplanocin A hydrochloride; DNMT; DNA methyltransferase; EZH2; enhancer of Zeste homolog 2; HDAC; histone deacetylase; H3K4me3; histone 3 lysine 4 trimethylation; H3K9acS10p; histone

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2

Keywords: 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; ACh; acetylcholine; AHR; aryl hydrocarbon receptor; ChIP; chromatin immunoprecipitation; c-NRF2; cytosolic NRF2; Ctrl; control; DM; diabetes mellitus; EC; endothelial cell; HDAC; histone deacetylase; HG; hig

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Co-targeting of BET proteins and HDACs as a novel approach to trigger apoptosis in rhabdomyosarcoma cells

Keywords: Apoptosis; Cell death; Mitochondria; HDAC; BET proteins; Rhabdomyosarcoma; JQ1; ARMS; alveolar rhabdomyosarcoma; BRD; bromodomain; BET protein; bromo- and extra-Terminal protein; CI; combination index; ERMS; embryonal rhabdomyosarcoma; EV; empty vector; F

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

Keywords: Autophagy; Combination therapy; Erlotinib; Vps34; High-content screening; AKT; Protein kinase B; ATG7; Autophagy-related protein 7; BafA1; Bafilomycin A1; Chk1; Checkpoint kinase 1; CQ; Chloroquine; FGFR; Fibroblast growth factor receptor; GFP; Green fluo

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy

Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure

Keywords: α/β-Cardiac Myosin; Heavy chain Alpha and Beta Cardiac Myosin; ABCG2; ATP-Binding Cassette sub-family G member 2; ANOVA; Analysis of Variance; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl Sulfoxide; DPBS; Dulbecco's Phosphate-Buffered Sali

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Diarylcyclopropane hydroxamic acid inhibitors of histone deacetylase 4 designed by combinatorial approach and QM/MM calculations

Keywords: Huntington's disease; Histone deacetylases; Inhibitors of HDAC4; Computer-assisted drug design; QM/MM approach; B3LYP; hybrid gradient-corrected exchange-correlation functional of electron density; CADD; computer-assisted drug design; DCHA; trans-(2R,3R)-

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors

Keywords: BET; Bromodomain and Extra-Terminal; BD1; bromodomain 1; BD2; bromodomain 2; KAc; acetylated-lysine; THQ; tetrahydroquinoline; BETi; Bromodomain inhibitors; HAT; histone acetyltransferase; HDAC; histone deacetylase; TR-FRET; time-resolved fluorescence res

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Caveolin-1 Controls Hyperresponsiveness to Mechanical Stimuli and Fibrogenesis-Associated RUNX2 Activation in Keloid Fibroblasts

Keywords: AFM; atomic force microscopy; COL; collagen; ECM; extracellular matrix; FN; fibronectin; HDAC; histone deacetylase; KFs; keloid fibroblasts; NFs; normal fibroblasts; PA; polyacrylamide; siNC; nontargeting control small interfering RNA; siRNA; small interf

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Cooperativity of HOXA5 and STAT3 Is Critical for HDAC8 Inhibition-Mediated Transcriptional Activation of PD-L1 in Human Melanoma Cells

Keywords: HDAC; histone deacetylase; HOXA5; homeobox A5; PD-1; programmed death 1; PD-L1; programmed death-ligand 1; shRNA; short hairpin RNA; STAT3; signal transducer and activator of transcription 3;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroprotective effects of valproic acid on brain ischemia are related to its HDAC and GSK3 inhibitions

Keywords: Valproic acid; Neuroprotection; Inflammation; Oxidative stress; HDAC; GSK3;

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Histone acetylation of oligodendrocytes protects against white matter injury induced by inflammation and hypoxia-ischemia through activation of BDNF-TrkB signaling pathway in neonatal rats

Keywords: HDAC; histone deacetylas; SB; sodium butyrate; WMI; white mater injury; LPS; lipopolysaccharide; HI; hypoxic-ischemia; CC; corpus callosum; SVZ; subventricular zone; DG; dentate gyrus; OL; oligodendroglial lineage; H&E; haematoxylin and eosin; BrdU; 5-bro

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

STAT3: The art of multi-tasking of metabolic and immune functions in obesity

Keywords: Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Long non-coding RNAs regulation in adipogenesis and lipid metabolism: Emerging insights in obesity

Keywords: lncRNAs; Obesity; White adipogenesis; Brown adipocyte differentiation; Lipid metabolism; Therapeutics; WAT; white adipose tissue; BAT; brown adipose tissue; Pparg; peroxisome proliferator-activated receptor γ; Cebpa; CCAAT/enhancer binding protein α; Fa

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2018 سفارش ترجمه

Functions and epigenetic aspects of miR-15/16: Possible future cancer therapeutics

Keywords: CLL; chronic lymphocytic leukemia; MicroRNAs; miRNAs; UTR; untranslated region; SAHA; suberoyl anilide hydroxamic acid; HDAC; histone deacetylase; miR-15/16; Epigenetics; Drug resistance; Drosha; Therapeutics; EMT;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Spirohydantoins and 1,2,4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation

Keywords: HDAC; Epigenetics; Spirohydantoin; Triazole;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

The potential for targeted rewriting of epigenetic marks in COPD as a new therapeutic approach

Keywords: COPD; Chronic obstructive pulmonary disease; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR/Cas9; Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-Associated Protein 9 (Cas9); CSC; Cigarette smoke co

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Connexins, important players in the dissemination of prostate cancer cells

Keywords: AGA; alpha-glycyrrhetinic acid; ALP; alkaline phosphatase; BMEC; bone marrow endothelial cells; BPH; benign prostatic hyperplasia; Cbx; carbenoxolone; CSC; cancer stem cells; Cx; connexin; CXCL12; C-X-C motif chemokine 12; CXCR4; C-X-C chemokine receptor

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Modulating autophagy in cancer therapy: Advancements and challenges for cancer cell death sensitization

Keywords: 3-MA; 3-Methyl Adenine; Akt; Protein kinase B; AMP; Adenosine monophosphate; AMPK; AMP-activated protein kinase; Atg; Autophagy related genes; ATP; Adenosine triphosphate; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; BCL-2; B-

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of a long-term treatment with metformin in dystrophic mdx mice: A reconsideration of its potential clinical interest in Duchenne muscular dystrophy

Keywords: DMD; Duchenne muscular dystrophy; DGC; dystrophin-associated glycoprotein complex; ECM; extracellular matrix; SIRT1; Sirtuin1; PGC-1α; peroxisome proliferator-activated receptor γ coactivator 1α; PPARγ; peroxisome proliferator-activated receptor γ; B

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

A Trichostatin A (TSA)/Sp1-mediated mechanism for the regulation of SALL2 tumor suppressor in Jurkat T cells

Keywords: AP4; Activating Protein 4; BAX; Bcl-2-associated X protein; Brd4; Bromodomain-containing protein 4; Brg1; Brahma-related gene-1; C2H2; Cys2-His2 zinc finger; CBP; CREB-binding protein; CDKN2A; Cyclin-Dependent Kinase Inhibitor 2A gene; CDKN1A; Cyclin-Depe

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2018 سفارش ترجمه

Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

Keywords: 15d-PGJ2; 15-deoxy-D12, 14prostaglandin J2; 15(S)-HETE; 15(S)-hydroxyeicosatetraenoic acid; ADP; adenosine diphosphate; AGE; advanced glycan end product; AMPA; α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid; ARE; antioxidant response element; AS; a

دانلود رایگان متن کامل مقاله ISI 75 صفحه سال انتشار : 2018 سفارش ترجمه

Oligodendrogliopathy in neurodegenerative diseases with abnormal protein aggregates: The forgotten partner

Keywords: 5-HT; 5-hydroxytryptamine; Aβ; β-amyloid; ABCA8; ATP binding cassette subfamily A member 8; AD; Alzheimer's disease; ADP; adenosine diphosphate; AGD; argyrophilic grain disease; ALS; amyotrophic lateral sclerosis; AMBRA-1; autophagy and beclin 1 regul

دانلود رایگان متن کامل مقاله ISI 131 صفحه سال انتشار : 2018 سفارش ترجمه

Short communicationSIRT2 inhibition reverses anhedonia in the VGLUT1+/− depression model

Keywords: BDNF; brain-derived neurotrophic factor; HDAC; histone deacetylase; PFC; prefrontal cortex; VGLUT1; vesicular glutamate transporter 1; Anhedonia; Imipramine; Histone acetylation; Sirtuin 2 (SIRT2); Prefrontal cortex (PFC); 33i; Major depression;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models

Keywords: MOPr; μ-opioid receptor; NRSF; neuron-restrictive silencer factor; REST; repressor element 1 silencing transcription factor; HDAC; histone deacetylase; nrse; neural restrictive silencer element; re1; repressor element 1; PAH; paired amphipathic helix; ST

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه