دانلود مقالات ISI درباره Hdac + ترجمه فارسی

Role of histone acetylation in activation of nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway by manganese chloride

Keywords: Manganese chloride; Neurotoxicity; NF-E2-related factor 2 (Nrf2); Heme oxygenase-1(HO-1); Histone acetylation; PD; Parkinson's disease; Nrf2; erythroid 2-related factor 2; HO-1; heme oxygenase 1; ROS; reactive oxygen species; GSH; reduced glutathione; PC1

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

BRM promoter insertion polymorphisms increase the risk of cancer: A meta-analysis

Keywords: CNKI; China National Knowledge Infrastructure; HWE; Hardy-Weinberg equilibrium; PA; Pancreatic adenocarcinoma; ESCC; squamous cell carcinoma; HCC; hepatocellular carcinoma; HNSCC; head and neck squamous cell carcinoma; LC; lung cancer; PCR-PAGE; polyacryl

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Transflammation: Innate immune signaling in nuclear reprogramming

Keywords: PRR; pattern recognition receptor; TLR; toll-like receptor; RIG-1; retinoid acid-inducible gene I; RLR; RIG-1-like receptor; ROS; reactive oxygen species; RNS; reactive nitrogen species; iPSC; induced pluripotent stem cell; ESC; embryonic stem cell; MHC;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

An impedance-based approach using human iPSC-derived cardiomyocytes significantly improves in vitro prediction of in vivo cardiotox liabilities

Keywords: Cardiotoxicity; Impedance; Cardiomyocytes; iPSC; In vitro; Drug discovery; CiPA; comprehensive in vitro proarrhythmia assay; hIPSC-CMs; human induced pluripotent stem cell cardiomyocytes; HDAC; histone deacetylase inhibitors;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

A new role of GCN2 in the nucleolus

Keywords: GCN2; Amino acid starvation; Nucleolus; p53; RNA polymerase III; ARPP P0; acidic ribosomal phosphoprotein P0; ATF4; activating transcription factor 4; BRF1; B-related factor 1; eIF2α; eukaryotic initiation factor 2 alpha subunit; FC; fibrillar center; GA

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of signaling mechanisms in the heart by thioredoxin 1

Keywords: Akt; protein kinase B; AMPK; Adenosine Monophosphate-activated Protein Kinase; Ang-II; Angiotensin-II; AP1; Activator protein 1 (AP-1); ASK1; Apoptosis Signal-regulating kinase; Atg4; Autophagy related-4; ATP; Adenosine Triphosphate; CDDP; cis-diammine-di

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Development of N-hydroxycinnamamide-based HDAC inhibitors with improved HDAC inhibitory activity and in vitro antitumor activity

Keywords: HDAC; Inhibitors; Antiproliferative activity; Selectivity;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Valproate increases dopamine transporter expression through histone acetylation and enhanced promoter binding of Nurr1

Keywords: Dopamine transporter; Epigenetics; HDAC; Valproate; Histone deacetylase; Pitx3; Nurr1;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of the Glycerol Transporter, Aquaporin-3, by Histone Deacetylase-3 and p53 in Keratinocytes

Keywords: AQP; aquaporin; GFP; green fluorescent protein; HDAC; histone deacetylase; SAHA; suberoylanilide hydroxamic acid;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

BCL11B-Mediated Epigenetic Repression Is a Crucial Target for Histone Deacetylase Inhibitors in Cutaneous T-Cell Lymphoma

Keywords: CTCL; cutaneous T-cell lymphoma; HDAC; histone deacetylase; HDACi; histone deacetylase inhibitor; IC50; half maximal inhibitory concentration; MF; mycosis fungoides; SAHA; suberoylanilide hydroxamic acid;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2017 سفارش ترجمه

The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells

Keywords: AG; aminoguanidine; AGE; advanced glycation end-product; Akt; protein kinase B; eNOS; endothelial NO synthase; ERK; extracellular signal-regulated protein kinase; Glo1; glyoxalase 1; HDAC; histone deacetylase; HUVECs; human umbilical vein endothelial cell

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Dimeric but not monomeric α-lactalbumin potentiates apoptosis by up regulation of ATF3 and reduction of histone deacetylase activity in primary and immortalised cells

Keywords: MAL; multimeric alpha lactalbumin; HAMLET/BAMLET; human/bovine alpha lactalbumin made lethal to tumours; LALBA; α-lactalbumin; HDAC; histone deacetylation; HDACi; Histone deacetylase inhibitor; TSA; Trichostain A; FIL; feed back inhibitor of lactation; A

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

BH3-only protein BIM: An emerging target in chemotherapy

Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy

Keywords: WEEPGMLPFALURN-LCFDUXPPSA-N; PARP; HDAC; Multitarget; Drug design; Antitumor;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

The E3 ubiquitin ligase MID1/TRIM18 promotes atypical ubiquitination of the BRCA2-associated factor 35, BRAF35

Keywords: BHC; BRAF-histone deacetylase; BRAF35/HMG20b; BRCA2-associated factor 35; CC; coiled-coil; coREST/RCOR1; REST corepressor 1; E1; UBE1, ubiquitin activating enzyme; E2; UBE2 ubiquitin conjugating enzyme; E3; ubiquitin ligase enzyme; FN3; fibronectin type I

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2017 سفارش ترجمه

Sub-cellular localization specific SUMOylation in the heart

Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d

دانلود رایگان متن کامل مقاله ISI 76 صفحه سال انتشار : 2017 سفارش ترجمه

Effects of Klotho on fibrosis and cancer: A renal focus on mechanisms and therapeutic strategies

Keywords: ACE; angiotensin converting enzyme; ADAM; a disintegrin and metalloproteinase; AKI; acute kidney injury; ANGII; angiotensin II; AT1; angiotensin II receptor type 1; AMPKα; AMP-activated protein kinase α; α-SMA; α-smooth muscle actin; CKD; chronic kidn

دانلود رایگان متن کامل مقاله ISI 82 صفحه سال انتشار : 2017 سفارش ترجمه

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

Keywords: Aβ42; β-amyloid42; ABCA1; ATP-Binding Cassette Transporter A1; AD; Alzheimers disease; ADAM; AD-related disintegrin and metalloprotease; AICD; APP- intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE; ApolipoproteinE;

دانلود رایگان متن کامل مقاله ISI 175 صفحه سال انتشار : 2017 سفارش ترجمه

In utero exposure to carcinogens: Epigenetics, developmental disruption and consequences in later life

Keywords: 5-mc; 5-methylcytosine; AhR; aryl hydrocarbon receptor; AKT; protein kinase B; BPA; bisphenol A; CNS; central nervous system; CS; cigarette smoke; DBP; dibenzo(α1) pyrene; DES; diethylstilboestrol; DNMT; N-methyltransferase; E2; 17-β-oestradiol; ED; end

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting epigenetic reader and eraser: Rational design, synthesis and in vitro evaluation of dimethylisoxazoles derivatives as BRD4/HDAC dual inhibitors

Keywords: Epigenetic; Protein-protein interactions; Bromodomain; HDAC; Antiproliferative activity;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies

Keywords: Cancer biology; Histone deacetylase (HDAC); Telomere; Alternative lengthening of telomere (ALT); Histone deacetylase 9 (HDAC9); Promyelocytic leukemia (PML); ALT; alternative lengthening of telomere; APB; ALT-associated promyelocytic leukemia nuclear body

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Epigenetic regulation of glucose-stimulated osteopontin (OPN) expression in diabetic kidney

Keywords: Diabetic kidney disease; Hyperglycemia; Histone modification; Osteopontin (OPN); Histone methyltransferase (HMT); Histone deacetylase (HDAC); DN; diabetes nephropathy; OPN; osteopontin; HDAC; histone deacetylase; HMT; histone methyltransferase; ChIP; chro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

DNA methylation in Huntington's disease: Implications for transgenerational effects

Keywords: HD; Huntington's disease; Htt; huntingtin; DNMT; DNA methyltransferase; HDAC; histone deacetylase; DNA methylation; Epigenetic; Transgenerational; Neurodegenerative;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Selective repression of gene expression in neuropathic pain by the neuron-restrictive silencing factor/repressor element-1 silencing transcription (NRSF/REST)

Keywords: ENCODE; encyclopedia of DNA elements; HDAC; histone deacetylase; MeCP2; methyl CpG binding protein 2; miRNA; micro-RNA; NRSF; neuron-restrictive silencing factor; REST; repressor element-1 silencing transcription; Epigenetics; Neuropathic pain; NRSF/REST;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Dysregulation of select ATP-dependent chromatin remodeling factors in high trait anxiety

Keywords: ChRF; ATP-dependent chromatin remodeling factor; CHD1/3/5; chromodomain helicase DNA-binding 1/3/5; SNF2H; sucrose nonfermenting 2 homolog; HDAC; histone deacetylase; ACF; ATP-utilizing chromatin assembly and remodeling factor; vHC; ventral hippocampus; H

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Over expression of miR-200c suppresses invasion and restores methotrexate sensitivity in lung cancer A549 cells

Keywords: MTX; methotrexate; miRNAs; microRNAs; HDAC; histone deacetylase; A549; MTX-sensitive cell line A549; A549/MTX; MTX-resistant cell line A549; RT-PCR; real time-PCR; MTT; 3-(4,5-dlmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; FCM; flow cytometry; Lun

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Ischemic preconditioning, retinal neuroprotection and histone deacetylase activities

Keywords: Retina; Neuroprotection; Protein acetylation; Ischemia; Preconditioning; HDAC;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewHOPX: The Unusual Homeodomain-Containing Protein

Keywords: AA; amino acid; HD; homeodomain; Hdac; histone deacetylase; HOPX; homeodomain-only protein homeobox; mRNA; messenger RNA;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity

Keywords: Lung cancer; HDAC; Sulforaphane; Chemoprevention; Mouse xenografts

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The model beetle Tribolium castaneum can be used as an early warning system for transgenerational epigenetic side effects caused by pharmaceuticals

Keywords: DPH; diphenhydramine; HAT; histone acetyltransferase; HDAC; histone deacetylase; KAT; lysine acetyltransferase; MBD; methyl-CpG binding domain protein; Mt; methyltransferase; Nap1; nucleosome assembly protein 1; Sap; Sin3A-associated protein; Sin3A; SIN3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Associate editor: B. TeicherBenefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

Keywords: GPR41; G protein-coupled receptor 41; GPR43; G protein-coupled receptor 43; GPR109A; G protein-coupled receptor 109A; HDAC; Histone deacetylases; DSS; dextran sulfate sodium; AOM; azoxymethane; APC; adenomatous polyposis; DC; dendritic cell; Treg; T regul

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Human γδ T cells: From a neglected lymphocyte population to cellular immunotherapy: A personal reflection of 30 years of γδ T cell research

Keywords: APC; antigen-presenting cell; BTN3A; butyrophilin 3A; HDAC; histone deacetylase; IPP; isopentenyl pyrophosphate; n-BP; nitrogen-containing bisphosphonate; Gamma/delta T cells; Immunotherapy; T-cell receptor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Nephrotoxicity of epigenetic inhibitors used for the treatment of cancer

Keywords: Epigenetic inhibitors; Prostate cancer; Kidney cells; Nephrotoxicity; 5-Aza; 5-aza-2ʹ-deoxycytidine; CBZ; carbamazapine; CDK; cyclin-dependent kinase; CDKN1a; cyclin-dependent kinase inhibitor 1a; CFZ; carfilzomib; ChIP; chromatin immunoprecipitation; DM

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The safety profile of vorinostat (suberoylanilide hydroxamic acid) in hematologic malignancies: A review of clinical studies

Keywords: Histone deacetylase inhibitors; HDAC; Safety; Vorinostat; Hematologic malignancies; Clinical trial

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Constitutive hyperactivity of histone deacetylases enhances radioresistance in Lepidopteran Sf9 insect cells

Keywords: HDAC; histone deacetylase; TL; tail length; TEM; tail extent moment; PTM; post-translational modification; TSA; trichostatin A; TAU; triton-acid urea; Radioresistance; Histone deacetylase; Histone post-translational modifications; Sf9 cells; DNA damage;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research updateOxidative stress, autophagy, epigenetic changes and regulation by miRNAs as potential therapeutic targets in osteoarthritis

Keywords: ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; AGEs; advanced glycation end products; ATG; autophagy-related gene; Col2; type II collagen; DNMT; DNA methyltransferase; ERK; extracellular signal-regulated kinase; HDAC; histone deac

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Isoflurane-induced inactivation of CREB through histone deacetylase 4 is responsible for cognitive impairment in developing brain

Keywords: CREB; HDAC; Isoflurane; Synapse;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research PaperDifferential expression of HDACs and KATs in high and low regeneration capacity neurons during spinal cord regeneration

Keywords: Spinal cord injury; Axonal regeneration; Epigenetic modifications; HDAC; KAT;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Review articleNucleus and nucleus-cytoskeleton connections in 3D cell migration

Keywords: 2D; Two dimension; 3D; Three dimension; ECM; Extracellular matrix; GCL; Germ cell-less; HDAC; Histone deacetylase; HMT; Histone methyltransferases; HP 1; Heterochromatin protein 1; INM; Inner nuclear membrane; LAP2β; Lamina-associated polypeptide-2β; LB

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators

Keywords: ACC; acetyl-CoA carboxylase; ADaM; allosteric drug and metabolite; AID; auto-inhibitory domain; α-RIM; α-regulatory interacting motif; AMPK; adenosine monophosphate-activated protein kinase; ASMS; affinity selection mass spectrometry; CamKKβ; Ca2+/calm

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Histone deacetylase inhibitors decrease NHEJ both by acetylation of repair factors and trapping of PARP1 at DNA double-strand breaks in chromatin

Keywords: HDAC; DSB repair; NHEJ; PARP1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential

Keywords: ATG; autophagy-related gene; AMPK; AMP activated protein kinase; BECN1; beclin1; b-TrCP; beta-transducin repeat-containing protein; Cbl; Casitas B-lineage lymphoma; CHIP; Carboxyl terminus of Hsc70 interacting protein; CHMP2B; charged multivesicular body

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis and biological evaluation of N-phenylquinazolin-4-amine hybrids as dual inhibitors of VEGFR-2 and HDAC

Keywords: N-Phenylquinazolin-4-amine hybrid; VEGFR-2; HDAC; Dual inhibitor

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Sodium valproate prevents radiation-induced injury in hippocampal neurons via activation of the Nrf2/HO-1 pathway

Keywords: BW; body weight; GSH; glutathione; GSK3; glucose synthase kinase-3; HDAC; histone deacetylase; HO-1; heme oxygenase-1; MDA; malondialdehyde; ROS; reactive oxygen species; siRNAs; short interfering RNAs; SOD; superoxide dismutase; sodium valproate; ionizin

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

N-Myc-interacting protein (NMI) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-κB/p65

Keywords: BRCA1; breast cancer 1; CBP; CREB-binding protein; EMT; epithelial-mesenchymal transition; HAT; histone acetyltransferase; HDAC; histone deacetylase; IFN; interferon; IKK; I-κB kinase; KAP1; Krüppel-associated box-associated protein; IRF; IFN regulatory

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Determination of pressure from measured Raman frequency shifts of anhydrite and its application in fluid inclusions and HDAC experiments

Keywords: Anhydrite; Raman spectroscopy; Geobarometry; HDAC; Fluid inclusions;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Sodium butyrate and its synthetic amide derivative modulate nociceptive behaviors in mice

Keywords: SCFA; short-chain fatty acid; HDAC; histone deacetylases; GPR41 and GPR43 respectively; free fatty acid receptor (FFAR)-2 and 3; PPARs; peroxisome proliferator-activated receptors; MTC1; monocarboxylate transporter 1; CCI; chronic constriction injury; FBA

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice

Keywords: B cells; HDAC; Systemic lupus erythematosus; T cells;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of rice histone deacetylase HDA705 in seed germination and in response to ABA and abiotic stresses

Keywords: HDAC; Oryza sativa L; Epigenetic; Germination; Stress;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Long non-coding RNA: A newly deciphered “code” in prostate cancer

Keywords: Androgen receptor; LNCaP; Biomarker; PCa; prostate cancer; ncRNA; non-coding RNAs; lncRNA; long ncRNA; miRNA; microRNA; snRNA; small nuclear RNA; siRNA; small interfering RNA; tRNA; transfer RNA; rRNA; ribosomal RNA; PCA3; PCa antigen 3; PIN; prostatic in

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه