Keywords: مانع HDAC; FK228 (PubChem CID: 5352062); PXD101 (PubChem CID: 6918638); SAHA (PubChem CID: 5311); LBH-589 (PubChem CID: 6918837); tubacin (PubChem CID: 6675804); tubastatin A (PubChem CID: 49850262); ACY-1215 (PubChem CID: 53340666); ACY-241 (PubChem CID: 53340426);
مقالات ISI مانع HDAC (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: مانع HDAC; Valproate; HDAC inhibitor; Histone deacetylase; In utero exposure; Environmental insult; Repetitive behavior; Sociability; Anxiety; Connectivity; Spines; Molecular changes;
Keywords: مانع HDAC; Histone acetylation; Creb-binding protein; Cbp; Sirtuin; HDAC inhibitor; Beta-hydroxybutyrylation; Dietary restriction; Ketogenic diet; Aging; Caloric restriction;
Keywords: مانع HDAC; Epigenetic modulator; Fluorescence-based assay; Quinic acid derivatives; HDAC inhibitor
Keywords: مانع HDAC; ATM; ataxia telangiectasia mutated; CDK; cyclin-dependent kinase; DMSO; dimethyl sulfoxide; HAT; histone acetyltransferase; HDAC; histone deacetylase; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NaB; sodium butyrate; PI; propidium i
Keywords: مانع HDAC; Gut microbiome; Butyrate; HDAC inhibitor;
Keywords: مانع HDAC; HDAC inhibitor; Nitric oxide; Benzofuroxan; Multifunctional drugs; Epigenetic;
Keywords: مانع HDAC; Plasmacytoid dendritic cells; HDAC inhibitor; Cytokines
Keywords: مانع HDAC; Histone deacetylase; HDAC inhibitor; Isoferulic acid; Anticancer;
Keywords: مانع HDAC; HDAC inhibitor; Peptides; Macrocycles; largazole; Disulfide bridge;
Keywords: مانع HDAC; Acetylation; HDAC inhibitor; Cell cycle arrest; Apoptosis; Leukemia; Cancer
Keywords: مانع HDAC; Histone deacetylase; HDAC inhibitor; Ferulic acid; Anticancer;
Keywords: مانع HDAC; Fear extinction; Metabotropic glutamate receptor; Epigenetics; HDAC inhibitor; Ventral striatum deep brain stimulation; NMDA receptor;
HSP72 functionally inhibits the anti-neoplastic effects of HDAC inhibitors
Keywords: مانع HDAC; HSP72; HDAC inhibitor; Sensitivity; Apoptosis;
The role of latency reversal agents in the cure of HIV: A review of current data
Keywords: مانع HDAC; HDAC inhibitor; HIV; Latency; Resting CD4+ T Cells;
Effects of Class II-Selective Histone Deacetylase Inhibitor on Neuromuscular Function and Disease Progression in SOD1-ALS Mice
Keywords: مانع HDAC; CMAPs; Compound muscle action potentials; FGFBP; fibroblast growth factor binding protein; HDACs; histone deacetylases; MEF; myocyte enhancer factor; PBS; phosphate-buffered saline; amyotrophic lateral sclerosis; HDAC inhibitor; SOD1G93A mice; skeletal mu
Epigenetics in myelodysplastic syndromes
Keywords: مانع HDAC; MDS; Epigenetics; ASXL1; DNMT3A; EP300; EZH2; IDH1; IDH2; KDM2B; KDM5A; KDM6A; MLL; MLL2; MLL3; MLL5; TET2; WT1; Hypomethylating agent; HDAC inhibitor;
Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects
Keywords: مانع HDAC; B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet
Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells
Keywords: مانع HDAC; Spinal muscular atrophy; HDAC inhibitor; iPSC; Neurons; Cyclic peptides;
EGCG, a tea polyphenol, as a potential mitigator of hematopoietic radiation injury in mice
Keywords: مانع HDAC; EGCG; HDAC inhibitor; Radiation; Micronucleus; CFC assay;
Therapeutic activity of the histone deacetylase inhibitor SB939 on renal fibrosis
Keywords: مانع HDAC; Renal fibrosis; TGF-beta; Myofibroblast; HDAC inhibitor;
Histone deacetylases in hearing loss: Current perspectives for therapy
Keywords: مانع HDAC; Histone deacetylase; HDAC inhibitor; Cochlea; Inner ear; Hearing loss;
XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts
Keywords: مانع HDAC; mTORC2; XPLN; SPARC; Idiopathic pulmonary fibrosis; HDAC inhibitor; ADHP; 10-Acetyl-3,7-dihydroxyphenoxazine; DAPI; 4â²,6-diamidino-2-phenylindole; ECM; extracellular matrix; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GEF; guanine nucleotide exchan
Research paperHistone deacetylase inhibitors suppress immature dendritic cell's migration by regulating CC chemokine receptor 1 expression
Keywords: مانع HDAC; Immature dendritic cell; HDAC inhibitor; MIP-1α; CCR1; Cell migration;
HDAC inhibitors: A new promising drug class in anti-aging research
Keywords: مانع HDAC; Epigenetics; HDAC inhibitor; Aging-related disease; Longevity; Healthspan; Lifespan extension;
Original ArticleIn vitro and in vivo anti-uveal melanoma activity of JSL-1, a novel HDAC inhibitor
Keywords: مانع HDAC; Uveal melanoma; Epigenetics; HDAC inhibitor; Migration and invasion; β-catenin; Cancer stem-like cells; UM; uveal melanoma; HDAC; histone deacetylase; HDACi; HDAC inhibitor; HAT; histone acetyltransferase; CSCs; cancer stem-like cells; ALDH; aldehyde deh
Effect of Class II HDAC inhibition on glutamate transporter expression and survival in SOD1-ALS mice
Keywords: مانع HDAC; Glutamate transporter EAAT2; HDAC inhibitor; SOD1G93A mice;
A novel SIRT1 inhibitor, 4bb induces apoptosis in HCT116 human colon carcinoma cells partially by activating p53
Keywords: مانع HDAC; Small molecule; HDAC inhibitor; Cell death; Bax; Caspase 3; Sirtuin;
Platinum(IV) prodrugs multiply targeting genomic DNA, histone deacetylases and PARP-1
Keywords: مانع HDAC; Multi-target; Pt(IV) prodrug; HDAC inhibitor; PARP-1 inhibitor; Overcoming drug-resistance;
Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
Keywords: مانع HDAC; HDAC inhibitor; Anti-proliferation; Western blot; Thienopyrimidine; Structure-activity relationship;
Phase I trial of vorinostat added to chemoradiation with capecitabine in pancreatic cancer
Keywords: مانع HDAC; HDAC inhibitor; Magnetic resonance imaging; Neoadjuvant therapy;
Suberoylanilide hydroxamic acid inhibits growth of head and neck cancer cell lines by reactivation of tumor suppressor microRNAs
Keywords: مانع HDAC; Suberoylanilide hydroxamic acid; HDAC inhibitor; Tumor suppressor miR; Head and neck cancer; PKCε; RhoC; miR-107; miR-138
The HDAC inhibitor SAHA improves depressive-like behavior of CRTC1-deficient mice: Possible relevance for treatment-resistant depression
Keywords: مانع HDAC; Mood disorders; Antidepressants; Animal model of depression; CREB coactivator; BDNF; HDAC inhibitor; SAHA; Epigenetics; Desipramine hydrochloride (PubChem CID: 65327); Vorinostat (PubChem CID: 5311);
Sodium butyrate reduces insulin-resistance, fat accumulation and dyslipidemia in type-2 diabetic rat: A comparative study with metformin
Keywords: مانع HDAC; Diabetes; Fat accumulation; Gluconeogenesis; HDAC inhibitor; Insulin-resistance; Sodium butyrateAc-H3/H4, Acetylated histone H3/H4; AKT-2, Protein kinase B; ANOVA, Analysis of variance; AUC, Area under curve; BAT, Brown adipose tissue; CH, Cholesterol; EL
KE108-conjugated unimolecular micelles loaded with a novel HDAC inhibitor thailandepsin-A for targeted neuroendocrine cancer therapy
Keywords: مانع HDAC; Neuroendocrine cancers; Somatostatin receptor; KE108 peptide; Unimolecular micelles; Targeted drug delivery; HDAC inhibitor
A novel approach to detect resistance mechanisms reveals FGR as a factor mediating HDAC inhibitor SAHA resistance in B-cell lymphoma
Keywords: مانع HDAC; SAHA; HDAC inhibitor; FGR; B-cell lymphoma; Drug resistance; BL; Burkitt lymphoma; CC; capture compound; CCMS; capture compound mass spectrometry; CRISPR; Clustered Regularly Interspaced Short Palindromic Repeats; DETECT; drug efficacy testing combined wi
4SC-202 activates ASK1-dependent mitochondrial apoptosis pathway to inhibit hepatocellular carcinoma cells
Keywords: مانع HDAC; Hepatocellular carcinoma (HCC); HDAC inhibitor; 4SC-202; Mitochondrial apoptosis pathway; ASK1 and cyclophilin-D;
Activation of mPTP-dependent mitochondrial apoptosis pathway by a novel pan HDAC inhibitor resminostat in hepatocellular carcinoma cells
Keywords: مانع HDAC; Hepatocellular carcinoma (HCC); HDAC inhibitor; Resminostat; mPTP; Mitochondrial apoptosis pathway; Sorafenib;
4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer
Keywords: مانع HDAC; HDAC6; HDAC inhibitor; Prostate cancer; Microtubular organization; HSP90α
Valproic acid reduces insulin-resistance, fat deposition and FOXO1-mediated gluconeogenesis in type-2 diabetic rat
Keywords: مانع HDAC; Diabetes; HDAC inhibitor; Gluconeogenesis; Insulin-resistance; Fat deposition; Sodium valproate;
The novel HDAC inhibitor AR-42-induced anti-colon cancer cell activity is associated with ceramide production
Keywords: مانع HDAC; Colon cancer; HDAC inhibitor; AR-42 and ceramide and apoptosis;
A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells
Keywords: مانع HDAC; I-7ab; HDAC inhibitor; Colorectal cancer; Apoptosis; Cell cycle arrest
Valproate attenuates the proteinuria, podocyte and renal injury by facilitating autophagy and inactivation of NF-κB/iNOS signaling in diabetic rat
Keywords: مانع HDAC; Autophagy; HDAC inhibitor; Diabetic nephropathy; NF-κB/iNOS signaling; Proteinuria; Sodium valproate; Ac-H3/Ac-H4; acetylated histone H3/H4; CaB; calbindin; CaM; calmodulin; DN; diabetic nephropathy; FITC; fluorescein isothiocyanate; HDACs; histone deace
Acetylation of intragenic histones on HPV16 correlates with enhanced HPV16 gene expression
Keywords: مانع HDAC; HPV16; Papillomavirus; Epigenetics; Histone marks; H3K9Ac; H3K36me3; H3K9me3; H4K20me3; H2BK5me1; HDAC inhibitor; Splicing; Polyadenylation; SR proteins; Hnrnp; Panobinostat; Quisinostat;
Disulfide cross-linked micelles of novel HDAC inhibitor thailandepsin A for the treatment of breast cancer
Keywords: مانع HDAC; HDAC inhibitor; Thailandepsin A; Disulfide cross-linked micelle; Targeted delivery; Breast cancer;
Evaluation of class I HDAC isoform selectivity of largazole analogues
Keywords: مانع HDAC; Largazole; HDAC inhibitor; Class I histone deacetylase; Isoform selectivity; Structure-activity relationship;
Treatment of chronically FIV-infected cats with suberoylanilide hydroxamic acid
Keywords: مانع HDAC; FIV; SAHA; Antilatency therapy; HIV; Animal model; HDAC inhibitor;
Efforts towards the synthesis of microsporin B: ready access to both the enantiomers of the key amino acid fragment
Keywords: مانع HDAC; HDAC inhibitor; Microsporin; Cross metathesis; Enzymatic resolution; Tetrapeptide;
Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells
Keywords: مانع HDAC; HDAC inhibitor; Tropolone; Natural product; Vorinostat; Leukemia;
Valproic acid attenuates the suppression of acetyl histone H3 and CREB activity in an inducible cell model of Machado–Joseph disease
Keywords: مانع HDAC; MJD; Valproic acid; HDAC inhibitor; CREB