دانلود مقالات ISI درباره مانع HDAC + ترجمه فارسی

The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth

Keywords: مانع HDAC; Thyroid cancer; Anaplastic; HDAC inhibitor; Thailandepsin A; TDP-A; Growth inhibition

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Valproate improves prepulse inhibition deficits induced by corticotropin-releasing factor independent of GABAA and GABAB receptor activation

Keywords: مانع HDAC; CRH; Corticosterone; Sensorimotor gating; HDAC inhibitor; GABA; Mood stabilizer;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC)

Keywords: مانع HDAC; HNSCC; Chromatin remodeling; HDAC inhibitor; Histone acetylation; NFκB; ChemoresistanceHNSCC, head and neck squamous cell carcinoma; NFκB, nuclear factor kappa B; DDR, DNA damage repair; DSB, double strand breaks; TSA, trichostatin A; IKKα, IκB kinase alp

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Non-toxic dose chidamide synergistically enhances platinum-induced DNA damage responses and apoptosis in Non-Small-Cell lung cancer cells

Keywords: مانع HDAC; HDAC inhibitor; Carboplatin; Cisplatin; Oxaliplatin; DNA damage; Non-small-cell lung cancer

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene

Keywords: مانع HDAC; Differentiation; HDAC inhibitor; Immediate early gene; Local chromatin structure; nur77 gene; PC12 cell

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity

Keywords: مانع HDAC; Bone marrow stromal cells; Histone deacetylase 8; Osteogenic differentiation; Histone H3 lysine 9 acetylation; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Histone deacetylase inhibitor (HDACI) mechanisms of action: Emerging insights

Keywords: مانع HDAC; HDAC inhibitor; DNA damage response; DNA repair; Cell cycle checkpoints; Apoptosis; Rational combinations; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; APAF-1; apoptotic protease activating factor 1; ASK1; apoptosis signal-regulating ki

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2014 سفارش ترجمه

Synergistic induction of miR-126 by hypoxia and HDAC inhibitors in cardiac myocytes

Keywords: مانع HDAC; Hypoxia; Cardiac myocytes; Micro-RNA-126; Tricostatin A; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

HDAC3 regulates stability of estrogen receptor α mRNA

Keywords: مانع HDAC; ERα; Breast cancer; HDAC inhibitor; HDAC3; mRNA stability; Cell proliferation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The novel HDAC inhibitor NDACI054 sensitizes human cancer cells to radiotherapy

Keywords: مانع HDAC; HDAC inhibitor; Ionizing radiation; Cancer cell lines; 3D cell culture; DNA repair;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Different effect of sodium butyrate on cancer and normal prostate cells

Keywords: مانع HDAC; Androgen receptor; Coregulators; HDAC inhibitor; Sodium butyrate; Acetylation; Prostate cells;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Histone deacetylase inhibitors suppress CXCR4-mediated dendritic cell migration by regulation of maturation process

Keywords: مانع HDAC; Dendritic cell; HDAC inhibitor; SDF-1α; CXCR4; Cell migration; Inflammation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Blockade of the ERK pathway enhances the therapeutic efficacy of the histone deacetylase inhibitor MS-275 in human tumor xenograft models

Keywords: مانع HDAC; ERK pathway; MEK inhibitor; HDAC inhibitor; Combination therapy; Synergistic drug interaction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The NR4A orphan nuclear receptors mediate transcription-dependent hippocampal synaptic plasticity

Keywords: مانع HDAC; Nr4a; Synaptic plasticity; Nuclear receptors; Hippocampus; Long-term potentiation; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis

Keywords: مانع HDAC; HDAC inhibitor; Histone acetylation; SAHA; Neurogenesis; Corticogenesis; Neural stem cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

HDAC inhibitor DWP0016 suppresses miR-22 to induce growth inhibition and apoptosis via p53-independent PTEN activation in neuroblastoma SH-SY5Y cells

Keywords: مانع HDAC; HDAC inhibitor; Apoptosis; miR-22; PTEN; PI3K/Akt pathway;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition of monomethylarsonous acid (MMAIII)-induced cell malignant transformation through restoring dysregulated histone acetylation

Keywords: مانع HDAC; HATs, histone acetyltransferases; HDACs, histone deacetylases; iAs, inorganic arsenic; MMAIII, monomethylarsonous acid; SAHA, suberoylanilide hydroxamic acidArsenic; Cell malignant transformation; HDAC inhibitor; Histone acetylation; Monomethylarsonous ac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Sulforaphane mitigates genotoxicity induced by radiation and anticancer drugs in human lymphocytes

Keywords: مانع HDAC; Sulforaphane; Radiation protection; Micronucleus; HDAC inhibitor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Combination of a novel HDAC inhibitor OBP-801/YM753 and a PI3K inhibitor LY294002 synergistically induces apoptosis in human endometrial carcinoma cells due to increase of Bim with accumulation of ROS

Keywords: مانع HDAC; HDAC inhibitor; PI3K inhibitor; Apoptosis; Bim; ROS

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Combination therapy: Histone deacetylase inhibitors and platinum-based chemotherapeutics for cancer

Keywords: مانع HDAC; Histone deacetylase; Cisplatin; Cancer; Chemotherapy; HDAC inhibitor; Combination therapy; Platinum drug

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells

Keywords: مانع HDAC; HDAC inhibitor; MHY219; Prostate cancer; Apoptosis; Cell cycle

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers

Keywords: مانع HDAC; Urothelial cancer; Histone deacetylase; HDAC inhibitor; Epigenetic; Targeted therapy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Development of programmable small DNA-binding molecules with epigenetic activity for induction of core pluripotency genes

Keywords: مانع HDAC; PI polyamides; SAHA derivatives; HDAC inhibitor; Gene activation; Induced pluripotent stem cell; Pluripotent stem cell;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Dihydrobenzofurans as cannabinoid receptor ligands from Cordyceps annullata, an entomopathogenic fungus cultivated in the presence of an HDAC inhibitor

Keywords: مانع HDAC; Entomopathogenic fungi; Secondary metabolites; HDAC inhibitor; Cannabinoid receptor; VCD;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Phase I Trial of Vorinostat Combined With Bortezomib for the Treatment of Relapsing and/or Refractory Multiple Myeloma

Keywords: مانع HDAC; Cell cycle; HDAC; HDAC inhibitor; Proteasome inhibitor; Suberoylanilide hydroxamic acid (SAHA); Synergistic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192

Keywords: مانع HDAC; HDAC inhibitor; Benzamide; MI-192; AML; Differentiation; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Biodistribution and metabolism of 11C-labeled Kendine 91 in mice and rats

Keywords: مانع HDAC; Carbon-11; PET; MRI; Kendine 91; Biodistribution; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro

Keywords: مانع HDAC; Spinal cord injury; HDAC inhibitor; Valproic acid; Neurons;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC–EGFR dual inhibitors

Keywords: مانع HDAC; N-Aryl salicylamides; HDAC inhibitor; EGFR inhibitor; Antiproliferative activity; Synthesis

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid

Keywords: مانع HDAC; Neurogenesis; Corticogenesis; mESCs; HDAC inhibitor; Valproic acid; Histone acetylation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Vorinostat, a histone deacetylase inhibitor, facilitates fear extinction and enhances expression of the hippocampal NR2B-containing NMDA receptor gene

Keywords: مانع HDAC; Extinction; HDAC inhibitor; Hippocampus; NR2B; Vorinostat;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Butyrate-induced GPR41 Activation Inhibits Histone Acetylation and Cell Growth

Keywords: مانع HDAC; GPR41; Butyrate; HDAC inhibitor; Anti-proliferation; Cell cycle arrest

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylase inhibitor, apicidin, inhibits human ovarian cancer cell migration via class II histone deacetylase 4 silencing

Keywords: مانع HDAC; HDAC inhibitor; Ovarian cancer; Migration; Apicidin; HDAC4

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease

Keywords: مانع HDAC; (HDAC); histone deacetylase; (HDACi); HDAC inhibitor; (HD); Huntington's disease; (Ppp1r1b); Protein phosphatase 1, regulatory (inhibitor) subunit 1B; (Htt); Huntingtin; Neurodegenerative; Striatum; Disease; Epigenetic; Therapeutic; Chromatin; Gene expres

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Chromatin-modifying agents in anti-cancer therapy

Keywords: مانع HDAC; Epigenetic inhibitors; HDAC; DNMT; Anti-cancer therapy; Clinical trials; Combinatory treatments; AML; acute myeloid leukemia; AZA; 5-azacytidine; CMA; chromatin-modifying agent; CML; chronic myeloid leukemia; CMML; chronic myelomonocytic leukemia; CTCL; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Proteins implicated in the increase of adhesivity induced by suberoylanilide hydroxamic acid in leukemic cells

Keywords: مانع HDAC; SAHA; Adhesion; Cofilin; Vimentin; PAK; HDAC inhibitor

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Role of Additional Novel Therapies in Myeloproliferative Neoplasms

Keywords: مانع HDAC; JAK2-V617F; HDAC inhibitor; hsp90 inhibitors; PI3K/AKT inhibitor; MEK inhibitor; Myeloproliferative neoplasms;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2012 سفارش ترجمه

A convenient procedure for the solid-phase synthesis of hydroxamic acids on PEGA resins

Keywords: مانع HDAC; Hydroxamic acids; Solid-phase synthesis; Hydroxylamine; HDAC inhibitor; PEGA resin;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

Keywords: مانع HDAC; HDAC inhibitor; dopamine; neuroprotection; valproateAcH3 Lys 9, acetylated histone 3 lysine 9; DA, dopamine; DAergic, dopaminergic; GSK3-β, glycogen synthase kinase-3β; HDAC, histone deacetylase; HDACi, histone deacetylase inhibitor; HPLC, high-pressure l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

ERK1/2 activation plays important roles in the opposite effects of Trichostatin A in non-cancer and cancer cells

Keywords: مانع HDAC; HDAC inhibitor; TSA; Apoptosis; ERK1/2; Non-cancer cells; Cancer cellsHDAC, histone deacetylase; MAPK, mitogen-activated protein kinase; ERK1/2, extracellular signal-regulated kinase 1/2; TSA, trichostatin A; MEK1, MAPKK1, mitogen-activated protein kinase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

TXNIP (VDUP-1, TBP-2): A major redox regulator commonly suppressed in cancer by epigenetic mechanisms

Keywords: مانع HDAC; Epigenetics; DNA methylation; Polycomb-repressive complex 2 (PRC2); MicroRNA; Histone modification; TXNIP/VDUP-1/TBP-2; Reactive oxygen species (ROS); Oxidative stress; HDAC inhibitor; DZNep; DNMT inhibitor; Solid tumor; Acute myeloid leukemia

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Glutathione-S-transferase pi 1(GSTP1) gene silencing in prostate cancer cells is reversed by the histone deacetylase inhibitor depsipeptide

Keywords: مانع HDAC; Histone; Methylation; Depsipeptide; Prostate cancer; HDAC inhibitor; GSTP1;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Epigenetics and autosomal dominant polycystic kidney disease

Keywords: مانع HDAC; Epigenetic; Autosomal dominant polycystic kidney disease; Histone deacetylases; HDAC inhibitor; α-Tubulin; Epidermal growth factor receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Apicidin, a histone deaceylase inhibitor, induces both apoptosis and autophagy in human oral squamous carcinoma cells

Keywords: مانع HDAC; HDAC inhibitor; Apicidin; Oral cancer; Cell cycle; Apoptosis; Autophagy; Oral squamous cell carcinoma

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Histone Deacetylase Inhibitors Sensitize Human Non-small Cell Lung Cancer Cells to Ionizing Radiation Through Acetyl p53-Mediated c-myc Down-Regulation

Keywords: مانع HDAC; Acetylation; c-myc; HDAC inhibitor; Ionizing radiation; p53

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

2′,4′,6′-Tris(methoxymethoxy) chalcone induces apoptosis by enhancing Fas-ligand in activated hepatic stellate cells

Keywords: مانع HDAC; 2′,4′,6′-Tris(methoxymethoxy) chalcone; Hepatic stellate cell; Apoptosis; HDAC inhibitor; Fas-ligand; Hepatic fibrosis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The role of class I histone deacetylase (HDAC) on gluconeogenesis in liver

Keywords: مانع HDAC; HDAC1; Phosphoenol pyruvate carboxykinase (PEPCK); Hepatocyte nuclear factor 4α (HNF4α); Forkhead box O 1 (FoxO1); HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Valproic acid improves outcome after rodent spinal cord injury: Potential roles of histone deacetylase inhibition

Keywords: مانع HDAC; Spinal cord injury; Histone acetylation; HDAC inhibitor; Valproic acid

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway

Keywords: مانع HDAC; Differentiation; HDAC inhibitor; Hematopoiesis; Inflammation; Stem cell;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis

Keywords: مانع HDAC; Amyotrophic lateral sclerosis (ALS); Mouse model; Treatment; HDAC inhibitor; Histone acetylation; Motoneurons; Astrocyte; Microglia; Neuromuscular junction; Motor function

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه