Keywords: A; adenine; ACMG; American College of Medical Genetics; Ala; alanine; Asp; aspartic acid; BCL2L12; B-cell lymphoma-2-like protein 12; BRCA1; breast cancer-1 gene; C; cytosine; CCDS; Consensus Coding Sequence; CD; circular dichroism; CDC; coding sequence;
مقالات ISI (ترجمه نشده)
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Keywords: Antimicrobial Peptide; Collagen; Inflammatory Bowel Disease; CD; Crohn's disease; DSS; dextran sulfate; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; HA; hemagglutinin; HEK293T; human e
Keywords: Transient transfection; Tubespins; Automation; Protein expression; HEK293T
Functional analysis of a novel ENG variant in a patient with hereditary hemorrhagic telangiectasia (HHT) identifies a new Sp1 binding-site
Keywords: Ab; antibody; ACTB; β-actin; ACVRL1; Activin A Receptor type II-Like Kinase 1; AVM; ArterioVenous Malformation; BMP; Bone Morphogenetic Protein; BMPR2; Bone Morphogenetic Protein Receptor Type 2; CAVM; Cerebral ArterioVenous Malformation; CTRL; control;
Upregulation of miR-215 exerts neuroprotection effects against ischemic injury via negative regulation of Act1/IL-17RA signaling
Keywords: Act1; nuclear factor activator 1; CCA; common carotid artery; ECA; external carotid artery; FITC; fluorescein isothiocyanate; HEK293T; human embryonic kidney 293T; ICA; internal carotid artery; IL-17RA; interleukin-17 receptor A; JNK; c-JuneN-terminal kin
The antitumor effect of TAT-DCF1 peptide in glioma cells
Keywords: GBM; glioblastoma; DCF1; dendritic cell-derived factor 1; TAT; transactivator of transcription; IPTG; isopropyl-β-thiogalactopyranoside; SDS-PAGE; sodium dodecyl sulfate polyacrylamide gel electrophoresis; RT; room temperature; PBS; phosphate buffered sa
Melanocortin-4 receptor in swamp eel (Monopterus albus): Cloning, tissue distribution, and pharmacology
Keywords: ACTH; Adrenocorticotropic hormone; AgRP; Agouti-related protein; α-MSH; α-melanocyte-stimulating hormone; BSA; bovine serum albumin; cAMP; 3â²,5â²-cyclic adenosine monophosphate; CNS; central nervous system; DMEM; Dulbecco's Modified Eagle Medium; ECL
Molecular and functional characterization of tumor-induced factor (TIF): Hamster homolog of CXCL3 (GROγ) displays tumor suppressive activity
Keywords: CXCL1; CXCL3; CXCR2; GRO; IL-8; MAS; Tumor-induced factor; Chemokine; Ab; antibody; CHO-K1; Chinese hamster ovary-K1; CNV; copy number variation; CXCR2; CXC chemokine receptor 2; CRE; cAMP-response elements; DCIP1; dendritic cell inflammatory protein 1; D
Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy
Keywords: A2058; human metastatic melanoma cell; A2780; human ovarian carcinoma cell; A2780cisR; cisplatin-resistant A2780; A375; human melanoma cell; A549; human lung adenocarcinoma epithelial cell; A549R; cisplatin-resistant A549 cell; Aβ; beta-amyloid; acac; ac
Molecular changes in appearance of a cancer cell among normal HEK293T cells
Keywords: Cellular competition; Co-culture; HEK293T; Proteome analysis; Tumor suppressor gene;
Cocaine modulates allosteric D2-Ï1 receptor-receptor interactions on dopamine and glutamate nerve terminals from rat striatum
Keywords: CREB; cAMP Response Element-Binding protein; CNS; central nervous system; D2R; D2 receptor; DA; dopamine; DAT; dopamine transporter; HEK293T; Human Embryonic Kidney cells 293; NER; net extra-outflow; Ï1Rs; Ï1 receptors; Cav 1.3; voltage dependent calciu
Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia
Keywords: Caulerpa taxifolia; Caulerpenyne; Oatp1d1; Oct1; Zebrafish; Effect-directed analysis (EDA); ASP+; 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide; CYN; caulerpenyne; EDA; effect-directed analysis; ESI; electrospray ionization; HEK293T; human embryon
Cry toxin specificities of insect ABCC transporters closely related to lepidopteran ABCC2 transporters
Keywords: ABC transporter; ATP-binding cassette transporter; ABCC transporter; ABC transporter subfamily C; HEK293T; human embryonic kidney 293 T; D-MEM; Dulbecco's modified Eagle medium; PEI; polyethylenimine; LDH; lactose dehydrogenase; Bacillus thuringiensis; Cr
An insight into the orphan nucleotide sugar transporter SLC35A4
Keywords: ER; endoplasmic reticulum; WM1341-D; human melanoma cell line; COS-7; African green monkey kidney cell line; HEK293T; human embryonic kidney 293 cells resistant to neomycin; HepG2; human liver cancer cell line; MDCK; Madin-Darby canine kidney II; MDCK-RCA
Toxicological impact of JWH-018 and its phase I metabolite N-(3-hydroxypentyl) on human cell lines
Keywords: Synthetic cannabinoids; JWH-018; JWH-018 N-(3-hydroxypentyl) metabolite; HEK293T; SH-SY5Y; Toxicity;
Development of a serodiagnostic multi-species ELISA against tick-borne encephalitis virus using subviral particles
Keywords: AP; alkaline phosphatase; BHK-21; baby hamster kidney fibroblast; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HEK293T; human embryonic kidney 293T; HRP; horseradish peroxidase; JEV; Japanese encephalitis virus; mAb; monoclonal antib
E3 ubiquitin ligase CHIP interacts with C-type lectin-like receptor CLEC-2 and promotes its ubiquitin-proteasome degradation
Keywords: CLEC-2; C-type lectin-like receptor 2; CHIP; C terminus of Hsc70-interacting protein; PMA; phorbol myristate acetate; CHX; cycloheximide; HEK293T; human emborynic kidney 293T; MS; mass spectrometry; FACS; fluorescence-activated cell sorting; ITAM; immunor
Pre-steady-state kinetic investigation of bypass of a bulky guanine lesion by human Y-family DNA polymerases
Keywords: 3-NBA; 3-nitrobenzanthrone; nitroPAH; nitro-polycyclic aromatic hydrocarbon; TA98; Salmonella typhimurium strain TA98; dGC8-N-ABA; N-(2â²-deoxyguanosin-8-yl)-3-aminobenzanthrone; TLS; translesion DNA synthesis; hPolη; human DNA polymerase eta; hPolκ; h
BRET-based β-arrestin2 recruitment to the histamine H1 receptor for investigating antihistamine binding kinetics
Keywords: H1R; histamine H1 receptor; GPCR; G protein-coupled receptor; NFAT; nuclear factor of activated T-cells; ERK; extracellular signal-regulated kinases; BRET; bioluminescence resonance energy transfer; HEK293T; Human embryonic kidney cells transformed with l
Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors
Keywords: Indoleamine 2; 3-dioxygenase 2; IDO2 bioassay system; IDO2 inhibitor; Tryptanthrin derivatives; hIDO2; human indoleamine 2, 3-dioxygenase 2; IDO1; indoleamine 2, 3-dioxygenase 1; L-1-MT; L-1-methyl-tryptophan; TDO; tryptophan 2, 3-dioxygenase; LLC; Lewis
The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5
Keywords: PRMT5; protein arginine methyltransferase 5; EGFR; epidermal growth factor receptor; TNF; tumor necrosis factor; NF-Y; nuclear factor Y; PKC; protein kinase C; Hsp90; heat shock protein 90; UPS; ubiquitin-proteasome system; CHIP; carboxyl terminus of he
Characterization of a ligand-gated cation channel based on an inositol receptor in the silkworm, Bombyx mori
Keywords: Gustatory receptor; Mulberry leaf; Inositol; Xenopus oocyte expression system; Ca2+ imaging; BmGr; Bombyx mori gustatory receptor; cRNA; capped RNA; MBS; modified Barth's saline; HEK293T; Human embryonic kidney 293Â T; D-MEM; Dulbecco's modified Eagle med
Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling
Keywords: BMDMs; bone marrow-derived macrophages; c-di-GMP; cyclic diguanylate monophosphate; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; GST; Glutathione S-transferase; HEK293T; human embryonic kidney; IB; immunobl
An endogenous ‘non-specific’ protein detected by a His-tag antibody is human transcription regulator YY1
Keywords: His-tag antibody; Yin and Yang 1 (YY1); Histidine-rich proteins; HeLa; HEK293T; ‘Non-specific’ band
Mapping of genomic double-strand breaks by ligation of biotinylated oligonucleotides to forum domains: Analysis of the data obtained for human rDNA units
Keywords: Forum domains; Double-strand breaks; Fragile sites; rDNA; Bioinformatics; HEK293T
Role of the salt bridge between glutamate 546 and arginine 907 in preservation of autoinhibited form of Apaf-1
Keywords: Apaf-1; apoptotic protease activating factor-1; CARD; caspase recruitment domain; NOD; nucleotide-binding and oligomerization domain; WRD; WD40-repeat domain; NBD; nucleotide-binding domain; HD1; helical domain 1; WHD; winged-helix domain; HD2; helical do
Genome-wide mapping of hot spots of DNA double-strand breaks in human cells as a tool for epigenetic studies and cancer genomics
Keywords: Double-strand breaks; Fragile sites; H3K4me3 marks; Bioinformatics; HEK293T
Roles of translesion synthesis DNA polymerases in the potent mutagenicity of tobacco-specific nitrosamine-derived O2-alkylthymidines in human cells
Keywords: NNK; 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone; NNN; N'-nitrosonornicotine; O2-Me-dT; O2-methylthymidine; O2-POB-dT; O2-[4-(3-pyridyl)-4-oxobut-1-yl]thymidine; HEK293T; human embryonic kidney 293T; TLS; translesion synthesis; MF; mutation frequency;
Hepatitis C virus NS3 protein enhances cancer cell invasion by activating matrix metalloproteinase-9 and cyclooxygenase-2 through ERK/p38/NF-κB signal cascade
Keywords: AP-1; activation protein-1; CMA; cell matrix adhesion; COX-2; cyclooxygenase-2; ECM; extracellular matrix; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; HBV; hepatitis B v
Oncogenic Human Papillomavirus 16E7 modulates SUMOylation of FoxM1b
Keywords: HPV; human papillomavirus; FoxM1b; Forkhead box transcription factor M1b; HEK293T; human embryonic kidney 293T cells; SUMO; small ubiquitin-like modifier; CHX; cycloheximide; PIAS1; protein inhibitor of activated STAT (signal transducer and activator of t
The inhibitory actions by lacosamide, a functionalized amino acid, on voltage-gated Na+ currents
Keywords: FBS; fetal bovine serum; HEK293T; human embryonic kidney cells; I-V; current-voltage; LCS; lacosamide; TEA; tetraethylammonium chloride; TTX; tetrodotoxin; lacosamide; Na+ current; use dependence; current inactivation; excitability;
BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs)
Keywords: AP; action potential; APP; amyloid precursor protein; BACE1; β-site APP-cleaving enzyme 1; DMEM; Dulbecco's modified Eagle's medium; DTT; dithiothreitol; EGFP; enhanced green fluorescent protein; FRAP; fluorescence recovery after photobleaching; HEK293T;
Biotransport and intracellular ice formation phenomena in freezing human embryonic kidney cells (HEK293T)
Keywords: HEK293T; Cryomicroscopy; Cryopreservation; Water transport; Intracellular ice formation (IIF); Optimal cooling rate;
Ligand-selective activation of heterologously-expressed mammalian olfactory receptor
Keywords: HEK293T; Olfactory receptor; mOR-EG; olfr73; Biased signaling; Functional assay
Induction of apoptosis through ER stress and TP53 in MCF-7 cells by the nanoparticle [Gd@C82(OH)22]n: A systems biology study
Keywords: ER; endoplasmic reticulum; ROS; reactive oxygen species; GO; gene ontology; qRT; quantitative real-time; TF; transcription factor; LTS; least trimmed squares; LMS; least median of squares; MLE; maximum likelihood estimator; HEK293T; human embryonic kidney
Regulation of the two kiss promoters in goldfish (Carassius auratus) by estrogen via different ERα pathways
Keywords: GPR54 or Kiss1R; G protein-coupled receptor 54; GnRH; gonadotropin-releasing hormone; ER; estrogen receptor; ERα; estrogen receptor α; ERβ; estrogen receptor β; Sp1; specificity protein-1; Sp3; specificity protein-3; ERE; estrogen response element; RN
Chromatin dynamics at the hTERT promoter during transcriptional activation and repression by c-Myc and Mnt in Xenopus leavis oocytes
Keywords: Ac; acetylation; AU; arbitrary units; bHLHZip; basic helix loop helix leucine zipper; bp; basepair; ChIP; chromatin immunoprecipitation; DMS; dimethylsulfate; DNase I; deoxyribonuclease I; dsDNA; double stranded DNA; EMSA; electrophoretic mobility shift a
Presenilins are novel substrates for TRAF6-mediated ubiquitination
Keywords: AD; Alzheimer's disease; AICD; APP intracellular domain; APH-1; anterior pharynx-defective-1; APP; Amyloid precursor protein; Aβ; Amyloid β; C99; 99-amino acid APP C-terminal fragment; ER; Endoplasmic reticulum; FAD; Familial Alzheimer's disease; HEK293
A replication-incompetent virus possessing an uncleavable hemagglutinin as an influenza vaccine
Keywords: MDCK; Madin-Darby canine kidney; HEK293T; human embryonic kidney 293T; HA; hemagglutinin; HA-MDCK; HA-expressing MDCK; MOI; multiplicity of infection; PFU; plaque-forming unit; FI; Formalin-inactivated virus; BAL; bronchoalveolar lavage; ELISA; Enzyme-lin
Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells
Keywords: PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex1; mTORC2; mTOR complex2; S6K1; p70 S6 kinase1; S6; ribosomal protein S6; 4E-BP1; eIF4E1 binding protein1; eIF2α; eukaryotic initiation factor 2α; PKR; ds RNA
Expression of recombinant sea urchin cellulase SnEG54 using mammalian cell lines
Keywords: Sea urchin; Stronglyocentrotus nudus; Cellulase; HeLa; HEK293T
The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity
Keywords: CPU; caudate putamen; DA; Dopamine; GFP; green fluorescent protein; HEK293T; human embryonic kidney 293T cells; NAc; nucleus accumbens; qRT-PCR; quantitative real-time polymerase chain reaction; shRNA; short hairpin RNA; siRNA; small interference RNA; VTA
Advantages of COS-1 monkey kidney epithelial cells as packaging host for small-volume production of high-quality recombinant lentiviruses
Keywords: Lentivirus; HEK293T; COS-1; Packaging cell
Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells
Keywords: Caspase-6; Caspase self-activation; Effector caspase; HEK293T; Caspase activation; Caspase activity; Alzheimer disease
Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling
Keywords: TSC; tuberous sclerosis complex; mTOR; mammalian target of rapamycin; Ub; ubiquitin; RNAi; RNA interference; Pam; Protein-associated with Myc; HIW; highwire; RPM-1; regulator of presynaptic morphology; RHD; regulator of chromosome condensation-homolgy dom
Regulation of melanin-concentrating hormone receptor 1 signaling by RGS8 with the receptor third intracellular loop
Keywords: CBB; Coomassie Brilliant Blue; DTT; dithiothreitol; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; GAP; GTPase-activating protein; GPCR; G protein-coupled receptor; GST; glutathione S-transferase; HA; hemagglutinin; HEK293T; human embryonic kid
The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway
Keywords: Cytochrome c; Drosophila; HEK293T; PDK-1; Severe Acute Respiratory Syndrome
Regulation of pharmacology by hetero-oligomerization between A1 adenosine receptor and P2Y2 receptor
Keywords: GPCR; Hetero-oligomer; Dimer; Purinergic receptor; P2 receptor; Adenosine receptor; Calcium mobilization; Adenylate cyclase; HEK293T