Keywords: عامل هسته ای هپاتوسیت 4 آلفا; T2D; Type 2 diabetes; GWAS; Genome wide association studies; SNPs; Single nucleotide polymorphisms; HWE; Hardy-Weinberg equilibrium; MAF; Minor frequency allele; He; expected heterozygosity; Ho; observed heterozygosity; AGTR2; Angiotensin II receptor, typ
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Keywords: عامل هسته ای هپاتوسیت 4 آلفا; monogenic diabetes; young type 2 diabetes; personalised medicine; CRP; C-reactive protein; HNF1A; hepatocyte nuclear factor 1 alpha; HNF4A; hepatocyte nuclear factor 4 alpha; HNF1B; hepatocyte nuclear factor 1 beta; GCK; glucokinase; IPSAD; International
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; APO; apolipoprotein; ACS; acyl-CoA synthetase; ACSL; acyl-CoA synthetase, long chain; ACAT; acyl-CoA:cholesterol acyltransferase; AGPAT; acylglycerophosphate acyltransferase; ATGL; adipocyte triglyceride lipase; 3BHS1; 3-Beta-hydroxysteroid dehydrogenase;
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; Neuroblastoma; Hepatocyte nuclear factor 4 alpha; Matrix metalloproteinase 14; Transcriptional regulation
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ABC; ATP-binding cassette; AE2 (SLC4A2); anion exchanger 2; ALT; alanine aminotransferase; AMPK; AMP-activated protein kinase; ALP; alkaline phosphatase; ASBT (SLC10A2); apical sodium-dependent bile acid transporter; ASCOM; activating signal cointegrator-
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ACAT; acyl-CoA cholesterol acyltransferase; ACC; acetyl CoA carboxylases; ACLY; ATP citrate lyases; ACSL; acyl CoA synthetases long chain family; ADRP; adipose differentiation related protein; AGP; advanced glycation end products; AGPAT; acylglycerophosph
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; LCM; laser capture microdissection; GH; growth hormone; STAT; signal transducer and activator of transcription; HNF4; hepatocyte nuclear factor 4 alpha; RIN; RNA integrity number; Hepatic zonation; Sexual dimorphism; Laser capture microdissection (LCM);
Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; MPS; microphysiological system; LDH; lactate dehydrogenase; ALT; alanine aminotransferase; BNF; beta-naphthoflavone; Rif; rifampin; EROD; ethoxyresorufin-O-deethylase; CYPs; cytochrome P450s; HNF4α; hepatocyte nuclear factor 4 alpha; MDZ; midazolam; AFB;
Cancer development, chemoresistance, epithelial to mesenchymal transition and stem cells: A snapshot of IL-6 mediated involvement
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; Cytokine; IL-6; Cancer stem cell; Chemoresistance and EMT; MAPK; mitogen-activated protein kinases; STAT3; signal transducer and activator of transcription 3; gp130; glycoprotein 130; C/EBP; CCAAT/enhancer-binding protein; JAK; Janus kinase; PI3K; phospho
Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; TLR3; HIV; Viral transactivation; LTR; NFκB; JNK; STAT1; Histone acetylation; Epigenetics; Human monocyte-derived macrophages; TZM-bl; U38 cells; AP-1; activator protein-1; B2M; beta-2-microglobulin; BCA; bicinchoninic acid; CAT; chloramphenicol acetyltr
Interleukin 6 inhibits HBV entry through NTCP down regulation
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; HBV; Hepatitis B virus; NTCP; Sodium taurocholate co-transporting polypeptide; IL-6; Interleukin 6; IFN γ; Interferon gamma; ALT; Alanine aminotransferase; TNFα; Tumor Necrosis Factor alpha; IL-1β; Interleukin 1 beta; OSM; Oncostatin M; PHH; Primary Hu
Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ChIP; chromatin immunoprecipitation; DNMT; DNA methyltransferase; EMT; epithelial to mesenchymal transition; MET; mesenchymal to epithelial transition; TGFβ; transforming growth factor β; HNF4α; hepatocyte nuclear factor 4 alpha; qPCR; real-time polyme
Ablation of Foxl1-Cre-Labeled Hepatic Progenitor Cells and Their Descendants Impairs Recovery of Mice From Liver Injury
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; HPCs; Oval Cells; Mouse Model; Nonalcoholic Fatty Liver Disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CDE; choline-deficient, ethionine-supplemented; CK19; Cytokeratin 19; CreER; Cre-estrogen receptor
Research ArticleTGFβ overrides HNF4α tumor suppressing activity through GSK3β inactivation: implication for hepatocellular carcinoma gene therapy
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; TGFβ; transforming growth factor β; EMT; epithelial-to-mesenchymal transition; HCC; hepatocellular carcinoma; HNF4α; hepatocyte nuclear factor 4 alpha; PTM; post-translational modification; GSK3β; glycogen synthase kinase-3 beta; BIO; GSK3β-inhibitor
In vitro microarray analysis identifies genes in acute-phase response pathways that are down-regulated in the liver of chicken embryos exposed in ovo to PFUdA
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; a2m; alpha-2-macroglobulin; APR; acute-phase response; cdo1; cysteine dioxygenase type I; CEH; chicken embryonic hepatocytes; cpb2; carboxypeptidase B2; DE; differentially expressed; DMSO; dimethyl sulfoxide; f2; thrombin (coagulation factor II); FDR; fal
Hepatocyte nuclear factor 4α regulates the expression of the murine pyruvate carboxylase gene through the HNF4-specific binding motif in its proximal promoter
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ChIP; chromatin immunoprecipitation; DR1; direct repeat 1; EMSA; electrophoretic mobility shift assay; FBPase; fructose-1,6-bisphosphatase; G6Pase; glucose-6-phosphatase; HIP1; housekeeping initiator protein 1; HNF4α; hepatocyte nuclear factor 4 alpha; M
Construction of a plasmid vector for liver-specific inhibition of hepatocyte nuclear factor 4 alpha expression
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; Hepatocyte nuclear factor 4 alpha; Short hairpin RNA; Liver specific
Allelic and phenotypic spectrum of plasma triglycerides
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ABL; abetalipoproteinemia; ANGPTL3; angiopoietin-like 3; ANGPTL4; angiopoietin-like 4; APOA4; apolipoprotein A-IV; APOA5; apolipoprotein A-V; APOB; apolipoprotein B; APOC2; apolipoprotein C-II; APOC3; apolipoprotein C-III; APOE; apolipoprotein E; CAD; cor
The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ACNAT; acyl-CoA:amino acid N-acyltransferase; ACOT; acyl-CoA thioesterase; ACOX3; acyl-CoA oxidase 3; BAAT; bile acid-CoA:amino acid N-acyltransferase; CA; cholic acid; CoASH; coenzyme A; CDCA; chenodeoxycholic acid; DMN-CoA; dimethylnonanoyl-CoA; FAAH; f
Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; CK19; cytokeratin 19; CFTR; cystic fibrosis transmembrane receptor; MafA; musculoaponeurotic fibrosarcoma oncogene homolog A; GP2; glycoprotein 2; Pdx1; pancreatic and duodenal homeobox factor 1; HNF4α; hepatocyte nuclear factor 4 alpha; TTR; transthyret
Induction of a mature hepatocyte phenotype in adult liver derived progenitor cells by ectopic expression of transcription factors
Keywords: عامل هسته ای هپاتوسیت 4 آلفا; ALDPC; adult liver-derived progenitor cells; iPS; induced pluripotent stem cells; LETF; liver enriched transcription factors; LD; liver differentiation medium; HBM; hepatocyte basal medium; MM; maintenance medium; ESC; embryonic stem cells; Foxa2; forkhea