The signaling and transformation potency of the overexpressed HER2 protein is dependent on the normally-expressed EGFR
Keywords: HER2; EGFR; Signaling; Transformation;
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Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines
Keywords: c-Src; Oestrogen receptor; HER2; Breast cancer cell lines;
New therapies in HER2-positive breast cancer: A major step towards a cure of the disease?
Keywords: Anti-HER2 antibodies; HER2; Metastatic breast cancer; Trastuzumab; Tyrosine-kinase inhibitors
EGFR, HER2, survivin, and loss of pSTAT3 characterize high-grade malignancy in salivary gland cancer with impact on prognosis
Keywords: Salivary gland cancer; EGFR; HER2; Survivin; pSTAT3; Prognosis
The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
Keywords: Motility; Cytoskeleton; Signaling; Adhesion; HER2; pH-regulation
Preclinical evaluation of anti-HER2 Affibody molecules site-specifically labeled with 111In using a maleimido derivative of NODAGA
Keywords: HER2; Affibody molecules; Radionuclides; Receptor targeting; Molecular imaging; Indium-111; Maleimido-NODAGA
Targeting high affinity and epitope-distinct oligoclonal nanobodies to HER2 over-expressing tumor cells
Keywords: Oligoclonal; Nanobodies; HER2; Breast cancer; Immunotherapy
Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies
Keywords: Stathmin; P-glycoprotein; Resistance; Taxane; p53; HER2; BRCA1/2; MRP-1;
Expression of activated HER2 in human testes
Keywords: Germ cells; HER2; human; soma; testis; tyrosine phosphorylated
Impact of chromosome 17 centromere region assessment on HER2 status reported in breast cancer
Keywords: Breast cancer; HER2; Chromosome17; Polysomy
Novel pyrrolo[2,1-f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases
Keywords: EGFR; HER2; Kinase inhibitor
Breast carcinomas with isolated bone metastases have different hormone receptor expression profiles than those with metastases to other sites or multiple organs
Keywords: Breast cancer; Estrogen receptor; Progesterone receptor; HER2; Bone metastasis
Genetic alterations and protein expression of HER2 and chromosome 17 polysomy in breast cancer
Keywords: HER2; Breast cancer; Chromosome 17; Polysomy; Immunohistochemistry; Fluorescence in situ hybridization
Trastuzumab combined to neoadjuvant chemotherapy in patients with HER2-positive breast cancer: A systematic review and meta-analysis
Keywords: Breast cancer; Neoadjuvant; Trastuzumab; Her2; Meta-analysis
A Phase I Study of Capecitabine, Oxaliplatin, and Lapatinib in Metastatic or Advanced Solid Tumors
Keywords: CapOx/lap; fluoropyrimidines; HER2
Estrogen receptor positive operable breast cancer: Does menopausal status impact on HER2 and progesterone receptor status?
Keywords: Estrogen receptor; Progesterone receptor; HER2; Breast cancer; MenopauseASCO, American Society of Clinical Oncology; CI, confidence interval; ER, estrogen receptor; FSH, follicle-stimulating hormone; HER2, human epidermal growth factor receptor 2; OR, odd
Significance of HER2 Protein Examination in Ductal Carcinoma In Situ
Keywords: breast; carcinoma; DCIS; HER2; biopsy
Quantum dots-based double-color imaging of HER2 positive breast cancer invasion
Keywords: Quantum dots; HER2; Type IV collagen; Breast cancer invasion;
Prognostic value of breast cancer subtypes on breast cancer specific survival, distant metastases and local relapse rates in conservatively managed early stage breast cancer: A retrospective clinical study
Keywords: Breast cancer subtypes; Breast-conserving surgery; Adjuvant radiotherapy; Estrogen receptor; Progesterone receptor; HER2
Increasing vaccine potency through exosome antigen targeting
Keywords: TAA; tumor associated antigens; APC; antigen presenting cells; ECD; extracellular domain; CEA; carcinoembryonic antigen; HER2; human epidermal growth factor receptor 2; MUC1; mucin 1; CDC; complement-dependent cytotoxicity; bmDC; bone marrow derived dendr
Topoisomerase II-α as a predictive factor of response to therapy with anthracyclines in locally advanced breast cancer
Keywords: Topoisomerase II-α; Breast cancer; Anthracycline; Neoadjuvant; Markers; HER2;
Lack of replication for the association between HER2 I655V polymorphism and breast cancer risk: A systematic review and meta-analysis
Keywords: HER2; Polymorphism; Ile655Val; rs1136201; Breast cancer; Systematic review; Meta-analysis;
FISH-based determination of HER2 status in circulating tumor cells isolated with the microfluidic CEE™ platform
Keywords: Microfluidic; CTC; HER2; FISH
A positive cross-regulation of HER2 and ER-α36 controls ALDH1 positive breast cancer cells
Keywords: HER2; ER-α36; ALDH1; Breast cancer stem cells
Age and Survival Estimates in Patients Who Have Node-Negative T1ab Breast Cancer by Breast Cancer Subtype
Keywords: Distant recurrence-free survival; HER2; Hormone receptor; Recurrence-free survival; Triple-negative breast cancer
Label-free Her2 detection and dissociation constant assessment in diluted human serum using a longitudinal extension mode of a piezoelectric microcantilever sensor
Keywords: Piezoelectric microcantilever; Longitudinal extension mode; Cancer antigen detection; Her2; Label-free; Dissociation constant
Inhibitor of Apoptosis (IAP) survivin is indispensable for survival of HER2 gene-amplified breast cancer cells with primary resistance to HER1/2-targeted therapies
Keywords: Survivin; HER2; Trastuzumab; Lapatinib; Breast cancer
Quantum dots-based molecular classification of breast cancer by quantitative spectroanalysis of hormone receptors and HER2
Keywords: Quantum dots; Breast carcinoma; Molecular classification; Hormone receptor; HER2; Quantitative analysis;
Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer
Keywords: Antibody-drug conjugate; HER2; Maytansinoid; T-DM1; Trastuzumab
A Phase II Study of Weekly Nanoparticle Albumin-Bound Paclitaxel With or Without Trastuzumab in Metastatic Breast Cancer
Keywords: Nab paclitaxel; HER2; Sensory neuropathy; SPARC; Veeda Oncology Network
Her2 Amplification is Significantly More Frequent in Lymph Node Metastases From Urothelial Bladder Cancer Than in the Primary Tumours
Keywords: Her2; Bladder cancer; Metastases; Survival; Tissue microarray; FISH
Affibody-based nanoprobes for HER2-expressing cell and tumor imaging
Keywords: Affibody; Bioconjugation; Nanoprobes; HER2; Molecular imaging;
New therapeutic approaches in breast cancer
Keywords: Breast cancer; Targeted therapy; HER2; EGFR; mTOR
Prevalence and Prognostic Role of Triple-Negative Breast Cancer by Race: A Surveillance Study
Keywords: Biologic markers; Breast neoplasms; Health status disparities; HER2; Race/ethnicity; Triple negative breast cancer
The effect of direct translocation across endosomes on the cytotoxicity of the recombinant protein e23sFv-Fdt-casp6 to HER2 positive gastric cancer cells
Keywords: HER2; Gastric cancer; Apoptosis; Translocation;
Comparative biodistribution of imaging agents for in vivo molecular profiling of disseminated prostate cancer in mice bearing prostate cancer xenografts: focus on 111In- and 125I-labeled anti-HER2 humanized monoclonal trastuzumab and ABY-025 Affibody
Keywords: HER2; Prostate cancer; Trastuzumab; Affibody molecule; Biodistribution; Radiolabeling
Advances in carcinogenesis: A historical perspective from observational studies to tumor genome sequencing and TP53 mutation spectrum analysis
Keywords: 6,4-PPs; pyrimidine(6-4)pyrimidone photoproducts; AK; Actinic Keratosis; BaP; benzo(a)pyrene; BPDE; benzo(a)pyrene diol epoxide; BCC; Basal cell carcinoma; CPD; cyclobutane pyrimidine dimers; CRC; colorectal carcinoma; ER; estrogen receptor; ERG; ETS re
Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells
Keywords: Trastuzumab resistance; Rac1; PTEN; IGF-IR; Akt; HER2
Flavonoid-enriched extracts from Nelumbo nucifera leaves inhibits proliferation of breast cancer in vitro and in vivo
Keywords: NLE; Nelumbo nucifera leaf extract; HPLC; high-performance liquid chromatography; FAS; fatty acid synthase; HER2; human epithelial growth factor receptor 2; cdk; cyclin-dependent kinase; CKIs; cdk inhibitors; ER; estrogen receptor; FAK; focal adhesion kin
Prognostic potential of topoisomerase IIα and HER2 in a retrospective analysis of early advanced breast cancer patients treated with adjuvant anthracycline chemotherapy
Keywords: Breast cancer; Anthracyclines; TOPOIIα; HER2; Prognostic potential
Current technologies for HER2 testing in breast cancer
Keywords: Breast cancer; CISH; FISH; HER2; MLPA; SISH
Consenso de la Sociedad Española de AnatomÃa Patológica (SEAP) y de la Sociedad Española de OncologÃa Médica (SEOM) sobre la determinación de HER2 en el carcinoma gástrico
Keywords: Carcinoma gástrico; HER2; ImnunohistoquÃmica; Hibridación in situ; Estandarización; Control de calidad; Gastric carcinoma; HER2; Immunohistochemistry; In situ hybridization; Standardization; Quality control;
HER2 Interacts With CD44 to Up-regulate CXCR4 via Epigenetic Silencing of microRNA-139 in Gastric Cancer Cells
Keywords: Trastuzumab/Herceptin; Cancer Cell Signaling; Histone Deacetylase; Metastasis-Associated Protein-1; CXCR4; C-X-C chemokine receptor type 4; GSP; gene-specific primer; H3K9; the ninth lysine of histone H3; HDAC; histone deacetylase; HER2; human epidermal g
Impact of American Society of Clinical Oncology/College of American Pathologists guideline recommendations on HER2 interpretation in breast cancer
Keywords: HER2; FISH; Immunohistochemistry; Breast carcinoma
Mucinous cystadenocarcinoma of the breast with amplification of the HER2-gene confirmed by FISH: The first case reported
Keywords: Mucinous; Cystadenocarcinoma; Breast; HER2; FISH
HER2-testing in 538 consecutive breast cancer cases using FISH and immunohistochemistry
Keywords: HER2; Breast cancer; Immunohistochemistry; HercepTest; FISH
Enhancement of paclitaxel-induced apoptosis in HER2-overexpressing human breast cancer cells by a pertuzumab mimetic peptide, HRAP
Keywords: HRAP; HER2; Paclitaxel; Pertuzumab; Breast cancer; Apoptosis
Review of Testing and Use of Adjuvant Trastuzumab across a Cancer Network - Are We Treating the Right Patients?
Keywords: Adjuvant therapy; breast cancer; HER2; trastuzumab;
Exemestane and Chemotherapy as First-line Treatment of Metastatic Breast Cancer: Results of a Phase II Study
Keywords: Advanced breast cancer; Anthracyline; HER2; Pneumonia; Pulmonary embolism; Trastuzumab
Detection of HER2 breast cancer biomarker using the opto-fluidic ring resonator biosensor
Keywords: Breast cancer; HER2; Ring resonator; Optical biosensor; Label-free