دانلود مقالات ISI درباره Her2 + ترجمه فارسی

Tyrosine kinase inhibitors for brain metastases in HER2-positive breast cancer

Keywords: Breast cancer; Central nervous system (CNS) metastases; HER2; Small-molecule tyrosine kinase inhibitors; Lapatinib; Neratinib; Afatinib; Tucatinib;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

An automated epifluorescence microscopy imaging assay for the identification of phospho-AKT level modulators in breast cancer cells

Keywords: Assay development; Automated microscopy; Breast cancer; Calcium channels; Gene silencing; High content analysis; EGF; Epidermal growth factor; EGFR; Epidermal growth factor receptor; EMT; Epithelial mesenchymal transition; HER2; Human epidermal growth fac

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Association study of miR-100, miR-124-1, miR-218-2, miR-301b, miR-605, and miR-4293 polymorphisms and the risk of breast cancer in a sample of Iranian population

Keywords: BC; breast cancer; CRC; colorectal cancer; CI; confidence intervals; ESCC; esophageal squamous cell carcinoma; HNSCC; head and neck squamous cell carcinoma; HCC; hepatocellular carcinoma; HER2; human growth factor receptor 2; miRNA; MicroRNA; OR; odd rati

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

HDAC inhibitors as epigenetic regulators for cancer immunotherapy

Keywords: AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Micropapillary urothelial carcinoma: evaluation of HER2 status and immunohistochemical characterization of the molecular subtype

Keywords: Urothelial bladder cancer; Micropapillary variant; HER2; Molecular subtype; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

An improved 99mTc-HYNIC-(Ser)3-LTVSPWY peptide with EDDA/tricine as co-ligands for targeting and imaging of HER2 overexpression tumor

Keywords: HER2; Imaging; LTVSPWY; HYNIC; Tumor; EDDA;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation

Keywords: Breast Cancer; c-KIT; Epigenetics; DNA methylation; Immunohistochemistry; ADH; Atypical ductal hyperplasia; BCA; Bicinchoninic acid; CML; Chronic myelogenous leukemia; CK5/6; Cytokeratin 5/6; CK903; Cytokeratin 903; DCIS; Ductal Carcinoma in situ; ER; Est

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Multivalent targeting and killing of HER2 overexpressing breast carcinoma cells with methotrexate-encapsulated tetra-specific non-overlapping variable domain heavy chain anti-HER2 antibody-PEG-liposomes: In vitro proof-of-concept

Keywords: Heavy chain antibodies; HER2; Immuno-PEG-liposome; Methotrexate; Oligoclonal VHH; Targeted drug delivery;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin®-conjugated PLGA-PEG nanoparticles for drug delivery

Keywords: NPs; nanoparticles; TNF-α; tumor necrosis factor alpha; PEG; polyethylene glycol; PLGA; poly (D L- lactide-co-glycolide); MALDI; matrix assisted laser desorption/ionization; TOF; time-of-flight; TFA; trifluoroacetic acid; DCM; dichloromethane; EDC; 1-eth

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Nitrated T helper cell epitopes enhance the immunogenicity of HER2 vaccine and induce anti-tumor immunity

Keywords: Human epidermal growth factor receptor 2; Universal T cell epitope; Anti-tumor immunity; Nitration; CTL; cytotoxic T lymphocyte; E:T; effector:target; HER2; Human epidermal growth factor receptor 2; LDH; lactate dehydrogenase; MHC; Major histocompatibilit

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A sensitive electrochemical aptasensing platform based on exonuclease recycling amplification and host-guest recognition for detection of breast cancer biomarker HER2

Keywords: Electrochemical aptasensing; HER2; RecJf exonuclease; Host-guest interaction; Homogeneous hybridization;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3Kα-selective inhibitor CYH33 in breast cancer

Keywords: PIK3CA; HER2; Akt; Patient-derived xenograft (PDX);

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

Dendrosomal nanocurcumin and exogenous p53 can act synergistically to elicit anticancer effects on breast cancer cells

Keywords: TNBC; Triple-negative breast cancer; ER; estrogen receptor; PR; progesterone receptor; HER2; human epidermal growth factor receptor-2; EMT; epithelial-mesenchymal transition; BMI1; B-lymphoma Moloney murine leukemia virus insertion region-1; ZEB1; zing fi

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer

Keywords: Gold nanoparticle; Trastuzumab resistance; HER2; Gastric cancer; Autophagy; Tmab; trastuzumab; HER2; human epidermal growth factor receptor 2; AuNP; gold nanoparticle; ECD; extracellular domain; ADCC; antibody-dependent cellular cytotoxicity; PTEN; phosph

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

ER stress and cancer: The FOXO forkhead transcription factor link

Keywords: Endoplasmic reticulum; ER stress; Cancer; FOXO; Forkhead transcription factors; Unfolded protein response; AKT; Protein Kinase B; AKT1; Protein Kinase B Alpha; AMPK; AMP-activated protein kinase; ASK1; Apoptosis Signal Regulated Kinase 1; ATF4; Activating

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

YAP promotes breast cancer metastasis by repressing growth differentiation factor-15

Keywords: ALPP; alkaline phosphatase; AREG; amphiregulin; α-SMA; alpha smooth muscle actin; BIRC5; baculoviral inhibitor of apoptosis repeat-containing 5; ChIP; chromatin immunoprecipitation; CTGF; connective tissue growth factor; DDIT4; DNA-damage inducible trans

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells

Keywords: CNOT2; Breast cancer; Tissue array; CAM; VEGF; CCR4-Not complex; carbon catabolite repressed 4-negative on TATA-less complex; EGFR; epidermal growth factor receptor; HER2; human epidermal growth factor receptor 2; TNBC; triple negative breast cancers; VEG

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib

Keywords: Autophagy; Combination therapy; Erlotinib; Vps34; High-content screening; AKT; Protein kinase B; ATG7; Autophagy-related protein 7; BafA1; Bafilomycin A1; Chk1; Checkpoint kinase 1; CQ; Chloroquine; FGFR; Fibroblast growth factor receptor; GFP; Green fluo

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Distinct apoptotic blocks mediate resistance to panHER inhibitors in HER2+ breast cancer cells

Keywords: Δψm; mitochondrial membrane potential; FCCP; carbonylcyanide-4-(trifluoromethoxy)-phenylhydrazone; FITC; fluorescein isothiocyanate; BSA; bovine serum albumin; JC-1; 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazolylcarbocyanine iodide; MO

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Ampullary carcinoma-A genetic perspective

Keywords: AVC; ampulla of vater carcinoma; KRAS; Kirsten rat sarcoma viral oncogene homolog; OS; overall survival; RFS; recurrence free survival; HER2; human epidermal growth factor receptor 2; BRAF; B rapidly activated fibrosarcoma; BRCA2; breast cancer 2; TP53; t

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview

Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2018 سفارش ترجمه

Liposome-chaperoned cell-free synthesis for the design of proteoliposomes: Implications for therapeutic delivery

Keywords: ABC; accelerated blood clearance; AUC; area under the curve; BACE1; β-site APPcleaving enzyme 1; C8bp; C8-binding protein; Cardiolipin; 1,3-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol; CDH2; N-cadherin; CF; cell-free; CHO; Chinese Hamster Ovary ce

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

Keywords: Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf

دانلود رایگان متن کامل مقاله ISI 68 صفحه سال انتشار : 2018 سفارش ترجمه

Achieving clear margins. Directed shaving using MarginProbe, as compared to a full cavity shave approach

Keywords: BCS; breast conserving surgery; IDC; invasive ductal carcinoma; DCIS; ductal carcinoma in situ; ER; estrogen receptor; PR; progesteron receptor; HER2; human epidermal growth factor receptor 2;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Ligand peptide-grafted PEGylated liposomes using HER2 targeted peptide-lipid derivatives for targeted delivery in breast cancer cells: The effect of serine-glycine repeated peptides as a spacer

Keywords: Liposomes; Targeting; PEG; Drug delivery; HER2;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

AGR2 associates with HER2 expression predicting poor outcome in subset of estrogen receptor negative breast cancer patients

Keywords: HER2; AGR2; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

The First Case of HER2+ Invasive Ductal Carcinoma Arising From a Breast Hamartoma and Literature Review

Keywords: Breast cancer; Her2; Hamartoma; DCIS; ductal carcinoma in situ; LCIS; Lobular carcinoma in situ; IDC; invasive ductal carcinoma; ILC; invasive lobular carcinoma;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Increased risk of SSEs in bone-only metastatic breast cancer patients treated with zoledronic acid

Keywords: b-MBC; bone-metastasized breast cancer; BP; bisphosphonate; CI; confidence interval; ER; estrogen receptor; HER2; human epidermal growth factor receptor 2; HR; hormone receptor; MBC; metastatic breast cancer; OR; odds ratio; PgR; progesterone receptor; SR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Pathobiology of HER 2 positive small invasive (T1a,b) breast cancer: “A wolf in sheep's clothing”

Keywords: Small breast cancer; HER2; Hormone receptors; Tumor grade; Nodal metastasis; Proliferation index;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Objective, domain-specific HER2 measurement in uterine and ovarian serous carcinomas and its clinical significance

Keywords: HER2; Intracellular domain; Extracellular domain; Serous carcinoma; Quantitative immunofluorescence; Targeted therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Real world patterns of care in HER2-overexpressing breast cancer: Results of a survey of TEACH clinical trial investigators in 2011

Keywords: Breast neoplasm; HER2; Health care disparities; Molecular targeted therapy;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

A potential pitfall in evaluating HER2 immunohistochemistry for gastric signet ring cell carcinomas

Keywords: Gastric cancer; signet ring cell carcinoma; immunohistochemistry; HER2; trastuzumab;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Creciendo juntos. Casos equívocos HER2 y guías clínicas

Keywords: HER2; Casos equívocos; Guías clínicas; Hibridación in situ; Carcinoma de mama; HER2; Equivocal cases; Clinical guides; In situ hybridization; Breast carcinoma;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

ESR1 single nucleotide polymorphism rs1062577 (c.*3804T > A) alters the susceptibility of breast cancer risk in Iranian population

Keywords: ATM; ataxia-telangiectasia mutated; BRCA1; BReast CAncer gene 1; BRCA2; BReast CAncer gene 2; CHECK2; checkpoint kinase 2; ER; estrogen receptor; ESR1; estrogen receptor 1; HER2; human epidermal growth factor 2; PR; progesterone receptor; PTEN; phosphatas

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperPACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression

Keywords: C23; Ac-[DLeu]LLLRVK-amba peptide; CS-FBS; charcoal stripped fetal bovine serum; ER+; estrogen-receptor-positive; HER2; human epithelial growth factor receptor 2 enriched; IHC; immunohistochemistry; ML; multi-leu peptide Ac-LLLLRVKR- NH2; PC; proprotein c

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Gene copy number variation and protein overexpression of EGFR and HER2 in distal extrahepatic cholangiocarcinoma

Keywords: EGFR; HER2; cholangiocarcinoma; distal; copy number variation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptional repression of HER2 by ANO1 Cl− channel inhibition in human breast cancer cells with resistance to trastuzumab

Keywords: Breast cancer; HER2; Resistance to HER2-targeted therapy; Ca2+-activated Cl− channel; ANO1; IGFBP5;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Piperlongumine downregulates the expression of HER family in breast cancer cells

Keywords: Breast cancer; HER1; HER2; HER3; Piperlongumine; Reactive oxygen species;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionBreast cancer biomarkers before and after neoadjuvant chemotherapy: does repeat testing impact therapeutic management?

Keywords: Breast cancer; Neoadjuvant; ER; PR; HER2; Repeat testing; Biomarker;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors

Keywords: Affibody molecule; 44Sc; DOTA; ZHER2:2891; HER2; PET imaging;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Erythro-austrobailignan-6 down-regulates HER2/EGFR/integrinβ3 expression via p38 activation in breast cancer

Keywords: Breast cancer; Erythro-austrobailignan-6, p38; Caspase-3; Topoisomerase; EGFR; EA6; Erythro-Austrobailignan-6; JNK; c-Jun N-terminal kinase; EGFR; epidermal growth factor receptor; SC; Saururus chinensis; CDK-4; cycle dependent protein kinase-4; HER2; hum

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Simvastatin inhibits tumor angiogenesis in HER2-overexpressing human colorectal cancer

Keywords: Simvastatin; Anti-angiogenesis; HER2; VEGF; Colorectal cancer;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Original contributionOverexpression of phosphoprotein phosphatase 2A predicts worse prognosis in patients with breast cancer: a 15-year follow-up

Keywords: TNBC; triple-negative breast cancer; IHC; immunohistochemistry; OS; overall survival; RFS; relapse-free survival; Breast cancer; PP2A; HER2; p-AKT; Ki-67;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate, shows promising antitumor activity in epithelial ovarian carcinoma with HER2/Neu expression

Keywords: SYD985; T-DM1; Antibody-drug conjugate; Ovarian serous carcinoma; HER2; Ado-trastuzumab emtansine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Prognostic value of tumour-infiltrating lymphocytes in small HER2-positive breast cancer

Keywords: Tumour-infiltrating lymphocytes; HER2; Stage pT1a-b breast cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Original research articleImmunohistochemical analysis of PTEN, HER2/neu, and ki67 expression in patients with gastric cancer and their association with survival

Keywords: PTEN; phosphatase and tensin homolog; HER2; human epidermal growth factor receptor 2; OS; overall survival; DFS; disease free survival; TNM; tumor-node-metastasis; PIP3; phosphatidylinositol-(3,4,5)-triphosphate; TK; tyrosine kinase; EGFRs; epidermal grow

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Targeting EGFR/HER2 heterodimerization with a novel anti-HER2 domain II/III antibody

Keywords: Breast cancer; HER2; Transmembrane signal transduction; Structural analysis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Adherence to the Western, Prudent and Mediterranean dietary patterns and breast cancer risk: MCC-Spain study

Keywords: BC; breast cancer; EpiGEICAM; epidemiological study of the Spanish Group for Breast Cancer Research (Grupo Español de Investigación en Cáncer de Mama); MCC-Spain; multicase-control study on common tumours in Spain; OR; odds ratio; 95%CI; 95% Confidence

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Study on molecular structure, spectroscopic properties (FTIR and UV-Vis), NBO, QTAIM, HOMO-LUMO energies and docking studies of 5-fluorouracil, a substance used to treat cancer

Keywords: Cancer; HER2; 5-Fluorouracil; Molecular modeling; DFT;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Cytologic assessment of estrogen receptor, progesterone receptor, and HER2 status in metastatic breast carcinoma

Keywords: Estrogen receptor; Progesterone receptor; HER2; Cytology; FNA; Metastasis; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه