دانلود مقالات ISI درباره ها Marchesi + ترجمه فارسی

توسعه روش متابولومیک شبه هدفمند مبتنی بر متابولیک با استفاده از کروماتوگرافی مایع همراه با طیف سنجی جرمی

Development of a metabolic pathway-based pseudo-targeted metabolomics method using liquid chromatography coupled with mass spectrometry

Keywords: ها Marchesi; LC; liquid chromatography; MS; mass spectrometry; MS/MS; tandem mass spectrometry; UPLC; ultra-high-performance liquid chromatography; MRM; multiple reaction monitoring; ESCC; esophageal squamous cell carcinoma; LC-MS; liquid chromatography-mass spectrome

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2019 سفارش ترجمه

آبجو تولید شده از طریق حفره های هیدرودینامیکی مقدار بیشتری از زانتوهومول و دیگر پرنیلفلاوونوئید ها را حفظ می

Beer produced via hydrodynamic cavitation retains higher amounts of xanthohumol and other hops prenylflavonoids

Keywords: ها Marchesi; Brewing; Hops; Hydrodynamic cavitation; Prenylated flavonoids; Xanthohumol; 3′;-GCN; 3′;-geranylchalconaringenin; 6-GN; 6-geranylnaringenin; BIAB; Brew In A Bag; CN; Cavitation Number; DMX; desmethylxanthohumol; EBC; European Brewery Convention; HESI;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

تغییرات وابسته به سن در مانع خون مغزی. یک مطالعه مقایسه ای ساختاری و عملکردی در موش های صحرایی جوان و جوان

Age-dependent changes at the blood-brain barrier. A Comparative structural and functional study in young adult and middle aged rats

Keywords: ها Marchesi; ABC; ATP-binding casette; aCSF; artificial cerebrospinal fluid; AP; anterior-posterior; aPPF; artificial peripheral perfusion fluid; AUC; area under the curve; BBB; blood-brain barrier; Cmax; maximum concentration; DMSO; dimethyl sulfoxide; DV; dorso-vetr

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

توسعه و اعتبار سنجی طیف سنجی جرمی کروماتوگرافی-دو بعدی برای اندازه گیری همزمان 5 نوع ضد قارچی آزول و 1 متابولیت فعال

Development and validation of a liquid chromatography-tandem mass spectrometry assay for the simultaneous quantitation of 5 azole antifungals and 1 active metabolite

Keywords: ها Marchesi; IFI; invasive fungal infection; TDM; therapeutic drug monitoring; PK; pharmacokinetics; AMR; analytical measuring range; MRM; multiple reaction monitoring; HESI; heated electrospray ionization; Azole; Antifungal; Invasive fungal infection; Therapeutic dru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

بررسی بیولوژیکی میکروالگها: استخراج مناسب با استفاده از اثر انگشت اسپکترومتر ماتریس کروماتوگرافی مایع با وضوح بالا به عنوان ابزار کلیدی برای مشخص کردن ویژگی های متابولیک موفقیت آمیز

Bioprospecting of microalgae: Proper extraction followed by high performance liquid chromatographic-high resolution mass spectrometric fingerprinting as key tools for successful metabolom characterization

Keywords: ها Marchesi; Cer; ceramides; DG; diacylglycerols; EPA; eicosapentaenoic acid; FWHM; full width at half maximum; HESI; heated electrospray; HILIC; hydrophobic interaction liquid chromatography; HPLC; high performance liquid chromatography; HRMS/MS; high resolution tand

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی ادرار 2 - {[2- (استیلامینو-2-کربوکسی اتیل سولفانیل} بوتانیدیک اسید، یک اسید مرپرتروکیک موشهای تحت درمان با اسید مالیک

Study of urinary 2-{[2-(acetylamino-2-carboxyethyl]sulfanyl}butanedioic acid, a mercapturic acid of rats treated with maleic acid

Keywords: ها Marchesi; COSY; correlation spectroscopy; DDW; double de-ionized water; GSH; glutathione; HESI; heated electro spray ionization; HMBC; heteronuclear multiple-bond correlation spectroscopy; HMQC; heteronuclear multiple-quantum correlation spectroscopy; LOD; limit of

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

ایمنی واکسن کمکی: تمرکز بر خود ایمنی

Safety of vaccine adjuvants: Focus on autoimmunity

Keywords: ها Marchesi; AID; autoimmune disorders; AF; adjuvant formulations; ASIA; autoimmune/inflammatory syndrome induced by adjuvants; CFA; complete Freund′s adjuvant; CIA; collagen-induced arthritis; DA; dark Agouti; DC; dendritic cells; EAE; experimental autoimmune encep

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

سنتز، بررسی و تجزیه و تحلیل ترکیبات آکریل آمید و گلیدیدید گلوتاتیون

Synthesis, characterization and analysis of the acrylamide- and glycidamide-glutathione conjugates

Keywords: ها Marchesi; AA; acrylamide; AAMA; N-acetyl-S-(2-carbamoylethyl)-cysteine; COSY; correlation spectroscopy; EH; epoxide hydrolase; GA; glycidamide; GAMA; N-acetyl-S-(2-hydroxy-2-carbamoylethyl)-cysteine; GSH; glutathione; GST; glutathione-S-transferase; HESI; heated el

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

پذیرش مقررات و استفاده از مطالعات سم شناسی باروری یک نسل در اروپا

Regulatory acceptance and use of the Extended One Generation Reproductive Toxicity Study within Europe

Keywords: ها Marchesi; ACSA; Agricultural Chemical Safety Assessment of the ILSI HESI; ARA; Actual Regulatory Acceptance by regulatory authorities; CARACAL; Competent Authorities for REACH and GLP; CLP; classification and labelling process; CMR; Carcinogenic, Mutagenic and Repr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

کروماتوگرافی مایع با کارآیی چند عاملی با روش اسپکترومتری توده ای با وضوح بالا برای کنترل باقی مانده های آفت کش، میکوتوکسین ها و آلکالوئیدهای پریرولیزیدین

Multi-analyte high performance liquid chromatography coupled to high resolution tandem mass spectrometry method for control of pesticide residues, mycotoxins, and pyrrolizidine alkaloids

Keywords: ها Marchesi; AGC; automatic gain control; AIF; all ion fragmentation; C-trap; curved linear trap; CRM; certified reference material; dd; data dependent; dSPE; dispersive solid phase extraction; EFSA; European Food Safety Authority; ESI; electrospray ionization; EU; Eu

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

رویکردها و ملاحظات برای ارزیابی ایمنی مسکن برای مواد شیمیایی محیطی: خلاصه کارگاه

Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: A workshop summary

Keywords: ها Marchesi; 2,4-D; 2,4-dichlorophenoxyacetic acid; ACD; allergic contact dermatitis; ACSA; agricultural chemical safety assessment; AFC; antibody forming cell; CP; cyclophosphamide; CT; carbon tetrachloride; DART; developmental and reproductive toxicology; DIT; devel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

چالش های کشف و توسعه داروهای استنشاقی: واکنش ماکروفاژ آلوئولار منجر شده است

Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses

Keywords: ها Marchesi; 3D; Three dimensional; AM; Alveolar macrophage; APSGB; Academy of Pharmaceutical Science of Great Britain; BAL; Bronchoalveolar lavage; CAD; Cationic amphiphillic drugs; COPD; Chronic obstructive pulmonary disease; DLCO; Diffusing capacity of the lung for

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

سنتز و فعالیت ضد التهابی گلوکوزینولات های معطر

Synthesis and anti-inflammatory activity of aromatic glucosinolates

Keywords: ها Marchesi; DCM; dichloromethane; DME; 1,2-dimethoxyethane; DMF; N,N-dimethylformamide; ESI; electrospray ionization; FTMS; fourier transform mass spectrometry; GLs; glucosinolates; HESI; heated electrospray ionization; HRMS; high resolution mass spectrometry; IR; in

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report

Keywords: ها Marchesi; Safety pharmacology; Cardiotoxicity; Human-induced pluripotent stem cell-derived cardiomyocytes; Multi-electrode array technology; APD; action potential duration; APC; automated patch clamp; CiPA; Comprehensive in vitro Proarrhythmia Assay; CSRC; Cardiac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Utilizing Threshold of Toxicological Concern (TTC) with high throughput exposure predictions (HTE) as a risk-based prioritization approach for thousands of chemicals

Keywords: ها Marchesi; AOPs; Adverse Outcome Pathways; FSANZ; Food Standards Australia New Zealand; HTE; High Throughput Exposure; HTS; high throughput screening; ILSI; International Life Sciences Institute; HESI; Health and Environmental Sciences Institute; RISK21; Risk Assess

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Comparison of one- and three-lead ECG to measure cardiac intervals and differentiate drug-induced multi-channel block

Keywords: ها Marchesi; Automated ECG analysis; Cardiac safety; CiPA; Electrocardiogram; HESI; Methods; Multichannel block; QT interval; QT subintervals; Spatial magnitude lead;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

A homologues prediction strategy for comprehensive screening and characterization of C21 steroids from Xiao-ai-ping injection by using ultra high performance liquid chromatography coupled with high resolution hybrid quadrupole-orbitrap mass spectrometry

Keywords: ها Marchesi; UHPLC-Q-Orbitrap MS; ultra high performance liquid chromatography with high resolution hybrid quadrupole-orbitrap mass spectrometry; HESI; heat electrospray ionization; TCMs; traditional Chinese medicines; Q-TOF-MS; hybrid quadrupole orthogonal time-of-fl

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Nano liquid chromatography-high-resolution mass spectrometry for the identification of metabolites of the two new psychoactive substances N-(ortho-methoxybenzyl)-3,4-dimethoxyamphetamine and N-(ortho-methoxybenzyl)-4-methylmethamphetamine

Keywords: ها Marchesi; NPS; new psychoactive substances; NBOMe; N-ortho-methoxybenzyl; 25B-NBOMe; 2-(4-bromo-2,5-dimethoxyphenyl)-N-(ortho-methoxybenzyl) ethanamine; 25C-NBOMe; 2-(4-chloro-2,5-dimethoxyphenyl)-N-(ortho-methoxybenzyl) ethanamine; 25I-NBOMe; 2-(4-iodo-2,5-dimetho

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

CiPA challenges and opportunities from a non-clinical, clinical and regulatory perspectives. An overview of the safety pharmacology scientific discussion

Keywords: ها Marchesi; Comprehensive In-Vitro Proarrhythmia assay; CiPA; hERG; Multiple cardiac ion channels; Proarrhythmia; QTc; Torsade de pointes; AV; atrioventricular; CiPA; Comprehensive In-Vitro Proarrhythmia Assay; CSRC; Cardiac Safety Research Consortium; DG; Discussion

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Cross - site comparison of excitation-contraction coupling using impedance and field potential recordings in hiPSC cardiomyocytes

Keywords: ها Marchesi; Arrhythmia; EAD; CardioExcyte 96; Cardiomyocytes; CiPA; Contractility; Extracellular field potential; hiPSC; Impedance; Safety pharmacology; AXG; Cor.4U®, hiPSC-CMs, Ncardia; BrCoV; Beat rate (beat period) coefficient of variation; CDI; iCell Cardiomyocy

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Research articleSimultaneous determination and pharmacokinetic study of twelve bioactive compounds in rat plasma after intravenous administration of Xuebijing injection by UHPLC-Q-Orbitrap HRMS

Keywords: ها Marchesi; UHPLC-Q-Orbitrap HRMS; ultra high performance liquid chromatography -Q exactive hybrid quadrupole-orbitrap high-resolution accurate mass spectrometry; IS; internal standard; HESI; heat electrospray ionization; LLOQ; the lower limit of quantitation; RE; re

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Research articleUHPLC-Q-Orbitrap-HRMS-based global metabolomics reveal metabolome modifications in plasma of young women after cranberry juice consumption

Keywords: ها Marchesi; HESI; heated electrospray ionization; HRMS; high-resolution mass spectrometer; PCA; principal component analysis; OPLS-DA; orthogonal partial least squares-discriminant analyses; QC; quality control; Cranberry juice; UHPLC-Q-Orbitrap-HRMS; Metabolomics; O

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Integration of the TGx-28.65 genomic biomarker with the flow cytometry micronucleus test to assess the genotoxicity of disperse orange and 1,2,4-benzenetriol in human TK6 cells

Keywords: ها Marchesi; BaP; benzo[a]pyrene; BT; 1,2,4-benzenetriol; 2DC; 2-dimensional hierarchical clustering; DO; disperse orange; HHRA; Human Health Risk Assessment; HESI; Health and Environmental Sciences Institute; MOA; Mode of Action; MN; micronucleus; NSC; Nearest Shrunk

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of Silybum marianum fruit constituents on the health status of rabbits in repeated 42‐day fattening experiment

Keywords: ها Marchesi; S. marianum; Silybum marianum; SM; silymarin; SB; silybin; GAP; good agricultural practices; FRAP; ferric reducing antioxidant power; TBARS; thiobarbituric acid reactive substances; SOD; superoxide dismutase; GPx; glutathione peroxidase; GSR; glutathione

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis, properties, antitumor and antibacterial activity of new Pt(II) and Pd(II) complexes with 2,2′-dithiobis(benzothiazole) ligand

Keywords: ها Marchesi; AO; Acridine Orange; BTA; Benzothiazole; DTBTA; 2,2′-dithiobis(benzothiazole); DTT; 1, 4-Dithiothreitol; DMF; dimethylformamide; DMSO; dimethylsulfoxide; EB; Ethidium Bromide; EDTA; Ethylenediaminetetraacetic acid; FACS; Fluorescence-Activated Cell Sort

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Rapid determination of 30 bioactive constituents in XueBiJing injection using ultra high performance liquid chromatography-high resolution hybrid quadrupole-orbitrap mass spectrometry coupled with principal component analysis

Keywords: ها Marchesi; UHPLC-Q-Orbitrap MS; ultra high performance liquid chromatography with high resolution hybrid quadruple-orbitrap mass spectrometry; HESI; heat electrospray ionization; LOD; the limit of detection; LOQ; the limit of quantitation; RE; relative error; RSD; r

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Computational approaches to understand the adverse drug effect on potassium, sodium and calcium channels for predicting TdP cardiac arrhythmias

Keywords: ها Marchesi; ANN; Artificial Neural Network; CASH; Cardiac Arrest Study Hamburg; CAST; Cardiac Arrhythmia Suppression Trial; Cav1.2; L-Type calcium channel; CiPA; Comprehensive in vitro Proarrhythmic Assay; CSRC; Cardiac Safety Research Consortium; DHPs; 4-Aryl-1,4-di

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Keywords: ها Marchesi; Regulatory toxicology; Transcriptomics; Metabolomics; Good laboratory practice (GLP); Weight-of-evidence (WoE); Adverse outcome pathway (AOP); Mode-of-action (MoA); Gene expression; Differentially expressed genes; ANOVA; Analysis of variance; AOP; Adverse

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative - Update on progress

Keywords: ها Marchesi; APD; action potential duration; AERS; adverse event reporting system; CiPA; Comprehensive in Vitro Proarrhythmia Assay; EAD; early after depolarizations; ECG; electrocardiogram; HESI; Health and Environmental Sciences Institute; HT; high throughput; hSC-C

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

HESI/FDA workshop on immunomodulators and cancer risk assessment: Building blocks for a weight-of-evidence approach

Keywords: ها Marchesi; Immunotoxicology; Immunotoxicity; Immunomodulation; Immunosuppression; Carcinogenicity; Cancer; Risk assessment; CTL; cytotoxic T-lymphocytes; EBV; Epstein-Barr virus; FDA; Food and Drug Administration; HESI; Health and Environmental Sciences Institute;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Micro-CT imaging: Developing criteria for examining fetal skeletons in regulatory developmental toxicology studies - A workshop report

Keywords: ها Marchesi; Concordance criteria; Developmental toxicology; Imaging; Micro-CT; Skeletal evaluation; GLP validation; 2-D; two-dimensional; 3-D; three-dimensional; CRO; contract research organization; DART; developmental and reproductive toxicology; EFD; embryo-fetal d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Profiling of complex lipids in marine microalgae by UHPLC/tandem mass spectrometry

Keywords: ها Marchesi; DG; diacylglycerols; DGDG; digalactosyldiacylglycerols; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; GL; glycolipids; HESI; Heated ElectroSpray Ionization; HILIC; hydrophilic interaction liquid chromatography; HRMS; high resolution mass spectrom

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation

Keywords: ها Marchesi; Comprehensive in vitro Proarrhythmia Assay (CiPA); Field potential data sampling and analysis; Induced pluripotent cell cardiomyocytes (hiPSC-CMs); Multi electrode array (MEA); Patch clamp technologies; Pending issues and solutions; Validation; Voltage se

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Development and analytical comparison of microflow and nanoflow liquid chromatography/mass spectrometry procedures for quantification of cardiac troponin T in mouse hearts

Keywords: ها Marchesi; AL KO; double knock-out for ApoE and receptor for LDL; ApoE; apolipoprotein E; AST; aspartate transaminase; CK; creatine kinase; cTnT; cardiac troponin T; TnC; troponin C; TnI; troponin I; HESI; heated electrospray; ICAT; isotope-coded affinity tags; iTRA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Liquid chromatography-tandem mass spectrometry assay for the EGFR inhibitor pelitinib in plasma

Keywords: ها Marchesi; AUC; area under the plasma drug concentration-time curve; EDTA; ethylenediaminetetraacetic acid; HESI; heated electrospray ionization; IS; internal standard; kA; absorption rate constant; QC; quality control; SD; standard deviation; SRM; selected reacti

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

A public-private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee

Keywords: ها Marchesi; ADRs; adverse drug reactions; CDER; Center for Drug Evaluation and Research; cTn; cardiac troponin; CV; cardiovascular; EMA; European Medicines Agency; EWG; Expert Working Group; ECG; electrocardiogram; HESI; Health and Environmental Sciences Institute; h

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

HESI Exams: Consequences and Remediation

Keywords: ها Marchesi; HESI; NCLEX-RN; Remediation; Nursing education; Online learning

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

HESI Admission Assessment Scores: Predicting Student Success

Keywords: ها Marchesi; Admission assessment; Nursing students; Attrition; Retention; HESI

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The transgenic mouse assay as an alternative test method for regulatory carcinogenicity studies—Implications for REACH

Keywords: ها Marchesi; REACH; Carcinogenicity; Transgenic mice; Alternative models; High production volume chemicals; Genotoxicity; ICH; NTP; HESI; Two-year rodent bioassay

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Uses and issues of biomonitoring

Keywords: ها Marchesi; Biomonitoring; Epidemiological studies; Population surveys; HESI

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه