دانلود مقالات ISI درباره Hif-1Α + ترجمه فارسی

Non-electron transfer chain mitochondrial defects differently regulate HIF-1α degradation and transcription

Keywords: Hypoxia; HIF-1α; Mitochondrial defects; MFAS II; Mpv17; MnSOD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1α, CXCR4 and CA9 in colorectal carcinoma

Keywords: Colorectal carcinoma; Prognosis; Survival; HIF-1α; CA9; CXCR4;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleMyocyte enhancer factor 2D promotes colorectal cancer angiogenesis downstream of hypoxia-inducible factor 1α

Keywords: MEF2D; HIF-1α; Angiogenesis; Colorectal cancer; CD31; cluster of differentiation 31; CDS; coding sequence; ChIP; chromatin immunoprecipitation; CM; conditioned medium; CRC; colorectal cancer; DMEM; Dulbecco's modified Eagle's medium; HCC; hepatocellular

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleRas inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway

Keywords: Metastasis; Ras; Ras inhibitors; LOX; PI3K; HIF-1α; CRC; colorectal cancer; LOX; lysyl oxidase; PI3K; phosphatidylinositol 3-kinase; HIF; hypoxia-inducible factor; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; ECM; extracellula

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Transcription factor SP1 mediates hyperglycemia-induced upregulation of roundabout4 in retinal microvascular endothelial cells

Keywords: Robo4; roundabout4; DR; diabetic retinopathy; HREC; human retinal endothelial cells; SP1; specificity protein 1; ChIP; chromatin immunoprecipitation; FVM; fibrovascular membranes; PDR; proliferative diabetic retinopathy; RPE; retinal pigment epithelial; V

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of extract of Pueraria tuberosa on expression of hypoxia inducible factor-1α and vascular endothelial growth factor in kidney of diabetic rats

Keywords: Diabetic nephropathy; HIF-1α; VEGF; Nephrin; Phytomedicine; Pueraria tuberosa;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Protective role of hypoxia-inducible factor-1α-dependent CD39 and CD73 in fulminant acute liver failure

Keywords: ALF; acute liver failure; HIF-1α; hypoxia inducible factor-1α; CD39; ecto-5′-nucleotidase 39; CD73; ecto-5′-nucleotidase 73; Acute liver failure; CD39; CD73; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

HIF-1α coordinates epigenetic activation of SIAH1 in hepatocytes in response to nutritional stress

Keywords: Epigenetics; Transcriptional regulation; HIF-1α; KDM3A; Histone demethylation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Propofol attenuates pancreatic cancer malignant potential via inhibition of NMDA receptor

Keywords: Propofol; CaMK II; HIF-1α; VEGF; NMDA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury

Keywords: Controlled cortical injury (CCI); Thyroid hormone; Deiodinase; HIF-1α; HIF-2α; Hypoxia-responsive genes; Thyroid hormone responsive genes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases

Keywords: ALP; alkaline phosphatase; AMPK; AMP-activated protein kinase; Ang II; angiotensin II; BER; base excision repair; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CHIP; carboxyl terminus of Hsp70-interacting protein; CLL; chronic lympho

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of Paeoniflorin against AOPP-induced oxidative injury in HUVECs by blocking the ROS-HIF-1α/VEGF pathway

Keywords: Paeoniflorin; AOPPs; Reactive oxygen species; HIF-1α; VEGF; AOPPs; advanced oxidation protein products; HUVECs; human umbilical vein endothelial cells; DCFH-DA; dichlorofluorescein-diacetate; ROS; reactive oxygen species; MMP; mitochondrial membrane pote

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleTanshinone IIA inhibits β-catenin/VEGF-mediated angiogenesis by targeting TGF-β1 in normoxic and HIF-1α in hypoxic microenvironments in human colorectal cancer

Keywords: Tanshinone IIA; Colorectal cancer; Hypoxia; Angiogenesis; β-catenin/TCF/LEF signaling pathway; TGF-β; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Ascorbic acid, but not dehydroascorbic acid increases intracellular vitamin C content to decrease Hypoxia Inducible Factor -1 alpha activity and reduce malignant potential in human melanoma

Keywords: BRAF; Murine sarcoma viral (v-raf) oncogene homolog B1; HIF-1α; Hypoxia inducible factor-1 alpha; PHD; prolyl hydroxylase; FIH; Factor Inhibiting HIF; AA; Ascorbic acid; A2P; Ascorbate 2-phosphate; DHA; Dehydroascorbic acid; EDHB; Ethyl 3, 4-dihydroxbeno

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Bisphenol A induces proliferative effects on both breast cancer cells and vascular endothelial cells through a shared GPER-dependent pathway in hypoxia

Keywords: BPA; Hypoxia; GPER; HIF-1α; VEGF; Tumor development;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise

Keywords: 8-OHdG; 8-hydroxy-2-deoxyguanosine; ABL1; ABL proto-oncogene 1; AhpC; alkyl hydroperoxide reductase; AKT1; V-Akt murine thymoma viral oncogene homolog 1; APEX1; endonuclease apurinic/apyrimidinic endodeoxyribonuclease 1; ARG1; arginase 1; ARG2; arginase 2

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Role of Cyclooxygenase-2 Pathway in Creating an Immunosuppressive Microenvironment and in Initiation and Progression of Wilms' Tumor

Keywords: WT; Wilms' tumor; COX-2; Cyclooxygenase-2; Wt1; Wilms' Tumor 1 gene; Igf2; Insulin Growth Factor2; HIF-1α; Hypoxia-inducible factor 1-alpha; IDO; Indolamine 2, 3-dioxygenase; TGF-β; Transforming growth factor beta; TNF-α; Tumor necrosis factor alpha; p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation

Keywords: 3-BrPA; 3-bromopyruvate; ΔΨm; mitochondrial membrane potential; DMS; dimethyl succinate; HDAC; histone deacetylase; ETC; electron transport chain; HIF-1; hypoxia-inducible factor 1; IGF-1R; insulin-like growth factor 1 receptor; IDH; isocitrate dehydrog

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1α

Keywords: ASK1; apoptosis signal-regulating kinase; NB; neuroblastoma; SP; side population; TLX; Dorosophla tailless homologue; MMP; mitochondrial membrane potential; TLX; ASK1; Neuroblastoma; HIF-1α; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

A marine sponge alkaloid derivative 4-chloro fascaplysin inhibits tumor growth and VEGF mediated angiogenesis by disrupting PI3K/Akt/mTOR signaling cascade

Keywords: 4-Chloro fascaplysin; Angiogenesis; Apoptosis; VEGF; PI3K/AKT/mTOR; 4-CF; 4-chloro fascaplysin; HUVEC; Human umbilical vascular endothelial cells; VEGF; Vascular endothelial growth factor; HIF-1α; Hypoxia-inducible factor-1α; MMP; Matrix metalloproteina

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells

Keywords: ChIP; chromatin immunoprecipitation; CRC; colorectal cancer; PCR; polymerase chain reaction; RT; reverse transcription; EMT; epithelial-mesenchymal transition; MET; mesenchymal-epithelial transition; Ascl2; Achaete scute-like 2; HIF-1α; hypoxia inducible

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

A tumoural angiogenic gateway blocker, Benzophenone-1B represses the HIF-1α nuclear translocation and its target gene activation against neoplastic progression

Keywords: Benzophenone-1B; Benzimidazole; Angiogenesis; HIF-1α; Solid tumour; Nuclear translocation;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Chemosynthesis pathway and bioactivities comparison of saponins in radix and flower of Panax notoginseng (Burk.) F.H. Chen

Keywords: ANOVA; Analysis of variance; AP-1; Activator Protein-1; DMSO; Dimethyl Sulfoxide; dNTPs; Deoxynucleotide Triphosphates; ESI; Electrospray Ionization; FBS; Fetal bovine serum; GAS; Interferon-Gamma Activated Sequence; GLC; Glucose; HIF-1α; Hypoxia Inducib

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Archival ReportAdaptive Activation of a Stress Response Pathway Improves Learning and Memory Through Gs and β-Arrestin-1-Regulated Lactate Metabolism

Keywords: Adrenergic receptor; Arrestin; G protein; HIF-1α; Memory; Stress;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Cannabidiol: State of the art and new challenges for therapeutic applications

Keywords: (5-HT)1A; 5-hydroxytryptamine receptor;  ∆9-THC; delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; A2A; adenosine receptor; AEA; anandamide; ALI; acute lung injury; Aml-1; acute myeloid leukemia; APP; amyloid precursor protein; AR; androgen r

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells

Keywords: Annexin V; FITC-conjugated annexinV; BCA; bicinchoninic acid; BNIP3; Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3; CBP; CREB-binding protein; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CHIP; chromatin immunoprecipitation; CHOP; CCAAT-en

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Circular RNA hsa_circ_0010729 regulates vascular endothelial cell proliferation and apoptosis by targeting the miR-186/HIF-1α axis

Keywords: Circular RNA; Vascular endothelial cells; Hsa_circ_0010729; miR-186; HIF-1α; HUVECs;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Study on the role of Hsa-miR-31-5p in hypertrophic scar formation and the mechanism

Keywords: HS; Hypertrophic scars; ECM; Extracellular matrix; HIF1α; Hypoxia inducible factor1 α; HSFBs; Hypertrophic scar fibroblasts; VEGF; Vascular endothelial growth factor; TIMP-1; Tissue inhibitors of metalloproteinase; TAD; Transcriptional activation domain

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of hypoxia-inducible factor-1α by prolonged in vivo hyperinsulinemia treatment potentiates cancerous progression in estrogen receptor-positive breast cancer cells

Keywords: Breast cancer; Type 2 diabetes mellitus; Hyperinsulinemia; HIF-1α; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of HIF-1α and its downstream targets in rat hippocampus after long-term simulated microgravity exposure

Keywords: Microgravity; Tail-suspension; Hippocampus; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

MiR-34a contributes to diabetes-related cochlear hair cell apoptosis via SIRT1/HIF-1α signaling

Keywords: miR-34a; T2DM; Hearing impairment (HI); SIRT1; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

NEU3 sialidase role in activating HIF-1α in response to chronic hypoxia in cyanotic congenital heart patients

Keywords: HIF-1α; Sialidase NEU3; Congenital heart defects; Chronic hypoxia; EGFR signaling pathway;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells

Keywords: FUCCI; Fluorescence ubiquitination cell-cycle indicator; HC; Hypoxia-conditioned; HIF-1α; Hypoxia-inducible factor-1α; MTs; Microtubules; MTAs; Microtubule-targeting agents; MCR; Mitotic cell rounding; NRX; Normoxic; PTX; Paclitaxel; PLA; Peloruside A;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

BH3-only protein BIM: An emerging target in chemotherapy

Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Impact of BRAF kinase inhibitors on the miRNomes and transcriptomes of melanoma cells

Keywords: ASNS; asparagine synthetase; AXL; proto-oncogene tyrosine kinase receptor AXL; BRAF; B-Raf proto-oncogene serine/threonine kinase/v-raf murine sarcoma viral oncogene homolog B; CCL2; chemokine C-C motif ligand 2; CE; coexpression coefficient; CHAC1; ChaC

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia decreases ROS level in human fibroblasts

Keywords: BNIP3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; CM-H2DCFDA; chloromethyl-2′,7′-dichlorodihydrofluorescein diacetate; Δψm; mitochondrial membrane potential; DTNB; 5,5'-dithiobis-(2-nitrobenzoic acid); FCCP; carbonyl cyanide p-(tri

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Dual signaling evoked by oxidized LDLs in vascular cells

Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Hypoxia induced cognitive impairment modulating activity of Cyperus rotundus

Keywords: Cyperus rotundus; GFAP; HIF-1α; Hippocampus; Hypoxia; Spatial reference memory;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells

Keywords: ACh; acetylcholine; CAC; citric acid cycle; DHE; dihydroethidium; FFAs; free fatty acids; HFD; high-fat diet; HIF-1α; hypoxic inducible factor-1α; HK; hexokinase; HUVECs; human umbilical vein endothelial cells; mPTP; mitochondrial permeability transitio

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells

Keywords: Leucine; Reactive oxygen species; Oxidative phosphorylation; Glycolysis; mTOR; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2017 سفارش ترجمه

Redox signaling in the gastrointestinal tract

Keywords: HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci

دانلود رایگان متن کامل مقاله ISI 150 صفحه سال انتشار : 2017 سفارش ترجمه

Prolyl hydroxylase 3 (PHD3) expression augments the development of regulatory T cells

Keywords: PHD3; DMOG; Th17; Tregs; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

PIAS3 enhances the transcriptional activity of HIF-1α by increasing its protein stability

Keywords: HIF-1α; PIAS3; Stabilization; SUMO E3 ligase; Transcriptional regulation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Targeting HIF-1α is a prerequisite for cell sensitivity to dichloroacetate (DCA) and metformin

Keywords: Cancer metabolism; Dichloroacetate; Glycolytic enzymes; HIF-1α; Metformin;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Neonatal bronchopulmonary dysplasia increases neuronal apoptosis in the hippocampus through the HIF-1α and p53 pathways

Keywords: Bronchopulmonary dysplasia; Hippocampus; Neuron; Apoptosis; HIF-1α; p53;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

STEAP4 and HIF-1α gene expressions in visceral and subcutaneous adipose tissue of the morbidly obese patients

Keywords: Obesity; Inflammation; STEAP4; HIF-1α; Adipose tissue;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The effect of 17α-ethynylestradiol induced intrahepatic cholestasis of pregnancy on placental P-glycoprotein in mice: Implications in the individualized transplacental digoxin treatment for fetal heart failure

Keywords: Intrahepatic cholestasis of pregnancy; Placenta; P-glycoprotein; HIF-1α; Digoxin; Fetal heart failure;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Stabilization of HIF-1α modulates VEGF and Caspase-3 in the hippocampus of rats following transient global ischemia induced by asphyxial cardiac arrest

Keywords: HIF-1α; VEGF; Caspase-3; Cardiac arrest; Cardiopulmonary resuscitation; Hippocampus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

The Vascular Endothelial Growth Factor-A phosphorylates Murine Double Minute-2 on its Serine 166 via the Extracellular Signal-Regulated Kinase 1/2 and p90 Ribosomal S6 Kinase in primary human endothelial cells

Keywords: Angiogenesis; Endothelial cell; Skeletal muscle; ERK1/2; extracellular signal-regulated kinase 1/2; HIF-1α; hypoxia inducible factor-1α; HDMECs; human dermal microvascular endothelial cells; MAPK; mitogen activated protein kinases; Mdm2; murine double m

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Transarterial Chemoembolization Using Sorafenib in a Rabbit VX2 Liver Tumor Model: Pharmacokinetics and Antitumor Effect

Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; HCC; hepatocellular carcinoma; HIF-1α; hypoxia-inducible factor 1α; m/z; mass-to-charge ratio; TAE-L; transarterial embolization with Lipiodol; TAE-S; transarterial embolization with sorafe

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه