دانلود مقالات ISI درباره Hif-1Α + ترجمه فارسی

Salvianolic acid B improves the disruption of high glucose-mediated brain microvascular endothelial cells via the ROS/HIF-1α/VEGF and miR-200b/VEGF signaling pathways

Keywords: Tight junction proteins; Salvianolic acid B; High glucose; HIF-1α; miR-200b;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Pulmonary, gastrointestinal and urogenital pharmacologyPotent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats

Keywords: HIF-1α; Combined allergic rhinitis and asthma syndrome; YC-1; Inflammation; Rat;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Eukaryotic translation initiation factor 5A (eIF5A) is essential for HIF-1α activation in hypoxia

Keywords: Acetylation; eIF5A; HIF-1α; Hypoxia; Hypusination;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

AK-1, a SIRT2 inhibitor, destabilizes HIF-1α and diminishes its transcriptional activity during hypoxia

Keywords: HIF; hypoxia-inducible factor; SIRT2; AK-1; HIF-1α; Hypoxia; Cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research articleLactate induced HIF-1α-PRMT1 cross talk affects MHC I expression in monocytes

Keywords: Lactate; Monocyte; MHC class I; PRMT1; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperHypoxia inducible factor 1α: A critical factor for the immune response to pathogens and Leishmania

Keywords: Leishmania; Pathogens; HIF-1α; Inflammation; Immunosuppression; Immunoregulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The ROS-mediated activation of STAT-3/VEGF signaling is involved in the 27-hydroxycholesterol-induced angiogenesis in human breast cancer cells

Keywords: 27HC; 27-hydroxycholesterol; BC; breast cancer; E2; estradiol; ER; estrogen receptor; HUVECs; human umbilical vein endothelial cells; HIF-1α; hypoxia induced factor-1 alpha; ROS; reactive oxygen species; STAT-3; signal transducer and activator of transcr

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiency by which HIF-1α mRNA is translated

Keywords: RNA helicase; Metastasis; Colon tumor; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

CITED2 controls the hypoxic signaling by snatching p300 from the two distinct activation domains of HIF-1α

Keywords: HIF-1α; hypoxia-inducible factor 1α; CITED2; CBP/p300-interacting transactivator with an ED-rich tail 2; FIH; factor inhibiting HIF; VHL; von Hippel-Lindau; NAD; N-terminal transactivation domain; CAD; C-terminal transactivation domain; CH1/2; Cystein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

20-HETE contributes to ischemia-induced angiogenesis

Keywords: AA; arachidonic acid; 20-HETE; 20-hydroxyeicosatetraenoic acid; EC; endothelial cells; HMVEC; human microvascular endothelial cells; VEGF; vascular endothelial growth factor; VEGFR2; vascular endothelial growth factor receptor 2; HIF-1α; hypoxia-inducibl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

4-O-galloylalbiflorin discovered from Paeonia lactiflora Pall. is a potential β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor

Keywords: Alzheimer's disease (AD); β-secretase (BACE1); β-amyloid peptide; Paeonia lactiflora Pall; 4-O-galloylalbiflorin; Docking; Aβ; β-amyloid peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; BACE1; β-site amyloid precursor protein cleavin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The expression and function of E3 ligase SIAH2 in acute T lymphoblastic leukemia

Keywords: T-ALL; SIAH2; PHD; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Treatment with an activator of hypoxia-inducible factor 1, DMOG provides neuroprotection after traumatic brain injury

Keywords: DMOG; HIF-1α; Angiogenesis; Traumatic brain injury; Cell death; Lesion volume;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Silencing of hypoxia inducible factor-1α gene attenuated angiotensin Ⅱ-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice

Keywords: Abdominal aortic aneurysm; HIF-1α; Inflammation; MMP; Neovascularity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportKnockout of programmed cell death 5 (PDCD5) gene attenuates neuron injury after middle cerebral artery occlusion in mice

Keywords: PDCD5; programmed cell death 5; RhPDCD5; recombinant human programmed cell death 5; MCAO; middle cerebral artery occlusion; VHL; von Hippel-Lindau tumor suppressor protein; Mdm2; mouse double minute 2 homolog; HIF-1α; hypoxia-inducible factor 1 alpha; BN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

AT1 receptor antagonism before ischemia prevents the transition of acute kidney injury to chronic kidney disease

Keywords: glomerular hypertrophy; HIF-1α; inflammation; proximal tubule; renal fibrosis; renal hypoperfusion; VEGF;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Amelioration of ER stress by 4-phenylbutyric acid reduces chronic hypoxia induced cardiac damage and improves hypoxic tolerance through upregulation of HIF-1α

Keywords: ER stress; Hypoxia; PBA; HIF-1α; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by limiting HIF-1α activation in hepatic ischemia/reperfusion injury

Keywords: I/R; ischemia/reperfusion; ROS; reactive oxygen species; SEVO; sevoflurane; PROP; propofol; PTP; permeability transition pore; HIF-1α; hypoxia-inducible factor 1 alpha; DFX; deferoxamine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; GS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Decorin as a multivalent therapeutic agent against cancer

Keywords: AMPKα; AMP-activated protein kinase, alpha; AP4; Activating enhancer binding protein 4; ATG; Autophagy-related gene; Bcl2; B-cell CLL/lymphoma 2; BRAF; Proto-oncogene B-Raf; ECM; Extracellular matrix; EGFR; Epidermal growth factor receptor; ERK; Extracel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial ferritin affects mitochondria by stabilizing HIF-1α in retinal pigment epithelium: implications for the pathophysiology of age-related macular degeneration

Keywords: Mitochondrial ferritin; Mitochondria; Age-related macular degeneration; HIF-1α; Neurodegeneration;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Neurobehavioral alterations plus transcriptional changes of the heat shock protein 90 and hypoxia inducible factor-1α in the crucian carp exposed to copper

Keywords: AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; ACS; amino cupric silver stain; Cu; copper; DIG; digoxigenin-11-dUTP; Dl; lateral part of the dorsal telencephalon; Dm; medial part of the dorsal telencephalon; HIF-1α; hypoxia inducible facto

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Polyphenol compounds and PKC signaling

Keywords: AP-1; activated protein-1; ARE; antioxidant response element; BBB; blood brain barrier; CAT; catalase; CHO; Chinese hamster ovary; DAG; diacylglycerol; EGFR; epidermal growth factor receptor; EGR; early growth response; ERK; extracellular signal-regulated

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Elevated Serum CD95/FAS and HIF-1α Levels, but Not Tie-2 Levels, May Be Biomarkers in Patients With Severe Endometriosis: A Preliminary Report

Keywords: CD95/FAS; HIF-1α; Tie-2; Endometriosis;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

CD271 Down-Regulation Promotes Melanoma Progression and Invasion in Three-Dimensional Models and in Zebrafish

Keywords: 3D; three-dimensional; HIF-1α; hypoxia inducible factor-1α; MIC; melanoma-initiating cell; MM; metastatic melanoma; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PM; primary melanoma;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions

Keywords: ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Involvement of hypoxia-inducible factor-1α in the oxidative stress induced by advanced glycation end products in murine Leydig cells

Keywords: HIF-1α; Leydig cell; Reactive oxygen species; Advanced glycation end products;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Role of HIF-1α in the hypoxia inducible expression of the thiamine transporter, SLC19A3

Keywords: HIF-1α; hypoxia inducible factor 1 α; THTR1; thiamine transporter 1; THTR2; thiamine transporter 2; HIF-1β; hypoxia inducible factor 1 β; FBS; fetal bovine serum; DFO; deferoxamine mesylate; HRE; hypoxia responsive element; WCL; whole cell lysates; PB

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

HIF-1 regulates insect lifespan extension by inhibiting c-Myc-TFAM signaling and mitochondrial biogenesis

Keywords: HIF-1α; C-Myc; TFAM; Developmental arrest; Lifespan extension; Helicoverpa armigera;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α

Keywords: Akt; protein kinase B; AMPK; AMP-activated protein kinase; AVOs; acidic vesicular organelles; BNIP3; BCL2/adenovirus E1B 19 kDa interacting protein 3; BNIP3L; BCL2/adenovirus E1B 19 kDa interacting protein 3-like; CCND1; cyclin D1; CFSE; 5-(6)-carboxyfl

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics

Keywords: AC; adenylyl cyclase; AI; anemia of inflammation; cdks; cyclin-dependent kinases; bFGF; basic fibroblast growth factor; BpT; 2-benzoylpyridine thiosemicarbazone; Bp4eT; 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone; Bp44mT; 2-benzoylpyridine 4,4-dimethyl-

دانلود رایگان متن کامل مقاله ISI 103 صفحه سال انتشار : 2016 سفارش ترجمه

The AMP-activated protein kinase (AMPK) and cancer: Many faces of a metabolic regulator

Keywords: AMPK; Tumor metabolism; mTOR; Warburg effect; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

hCG stimulates angiogenic signals in lymphatic endothelial and circulating angiogenic cells

Keywords: hCG; human chorionic gonadotropin; HIF-1α; hypoxia inducible factor-1α; CXCL12; C-X-C motif chemokine 12; CXCR4; C-X-C chemokine receptor type 4; CAC; circulating angiogenic cells; LH; luteinizing hormone; LEC; lymphatic endothelial cells; UTM; uterine

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA in prostate cancer

Keywords: DGCR8; Digeorge syndrome chromosomal region 8; CCNDs; cyclin Ds; CDK4; cyclin-dependent kinase 4; CDK6; cyclin-dependent kinase 6; E2F; E2 transcription factor; E2F2; E2 transcription factor 2; IGF1R; insulin-like growth factor 1 receptor; ELK1; ELK1 memb

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

HIF-1α regulates bone formation after osteogenic mechanical loading

Keywords: Hypoxia inducible factor; HIF-1α; Mechanical loading; Osteogenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro inhibitory activities of six gypenosides on human liver cancer cell line HepG2 and possible role of HIF-1α pathway in them

Keywords: Gypenosides; Gynostemma pentaphyllum; Cytotoxic activity; HepG2; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Silencing of HIF-1α enhances the radiation sensitivity of human glioma growth in vitro and in vivo

Keywords: Gliomas; Radiation sensitivity; HIF-1α; RNAi; Pathway;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia

Keywords: SIRT1; HIF-1α; Stabilization; Deacetylation; Interaction; Invasion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Bisphenol A alters the cardiovascular response to hypoxia in Danio rerio embryos

Keywords: Endocrine disruption; Bisphenol A; Hypoxia; Zebrafish; Cardiovascular; Co-exposure; HIF-1α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

RGS19 converts iron deprivation stress into a growth-inhibitory signal

Keywords: Regulator of G-protein signaling; N-myc downstream-regulated gene 1 protein; Cysteine string motif; Iron-binding protein; AC; adenylyl cyclase; CCI; CREB-CBP binding inhibitor; CCK-8; cell counting kit-8; CREB; cAMP response element-binding protein; CSM;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo

Keywords: Angiogenesis; HIF-1α; Mitochondria; Pro-angiogenic agent; PTD; UQCRB;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The inducible E3 ubiquitin ligases SIAH1 and SIAH2 perform critical roles in breast and prostate cancers

Keywords: Cytokine; Estrogen; Sex hormone; SIAH1; SIAH2; ACK1/TNK2; activated CDC42-associated kinase 1; AR; androgen receptor; ATM; ataxia telangiectasia mutated; ATR; ataxia telangiectasia mutated related; BF; biochemical failure; DCC; deleted in colorectal cance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation

Keywords: Osteoclast; Autophagy; Hypoxia; HIF-1α; microRNAs; Periodontal disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Combined effects of EGFR tyrosine kinase inhibitors and vATPase inhibitors in NSCLC cells

Keywords: Bnip3; Epidermal growth factor receptor; Hif-1α; Tyrosine kinase inhibitors; vATPase inhibitors;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Posttranslational modification of Sirt6 activity by peroxynitrite

Keywords: HIF-1α; hypoxia-inducible factor-1α; HRMEC; human retinal microvascular endothelial cell; Sirt; sirtuin; LPS; lipopolysaccharide; NAD; nicotinamide adenine dinucleotide; NT; nitrotyrosine; PARP-1; mono-ADP-ribosylating poly(ADP-ribose) polymerase 1; SIN

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain

Keywords: CNS; central nervous system; COX; cyclooxygenase; ECA; external carotid artery; Hif-1α; hypoxia-inducing factor-1α; Hsp70; heat shock protein 70; ICA; internal carotid artery; MCAO; middle cerebral artery occlusion; MT-1/2; metallothionein-1/2; MTF-1; m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cellular repressor of E1A-stimulated gene overexpression in bone mesenchymal stem cells protects against rat myocardial infarction

Keywords: BMSCs; CREG; HIF-1α; Myocardial infarction; VHL;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2

Keywords: AMC; 7-amino-4-methylcoumarin; CDDO-Me; methyl-2-cyano-3,12-dioxooleana-1, 9(11)dien-28-oate; DNCB; 2,4-dinitrochlorobenzene; Gclm; glutamate-cysteine ligase regulatory subunit; HIF-1α; hypoxia-inducible factor 1α; IAA; iodoacetamide; Keap1; Kelch-lik

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Protein kinase CK2 inhibition is associated with the destabilization of HIF-1α in human cancer cells

Keywords: Protein kinase CK2; Kinase inhibitors; HIF-1α; Murine xenograft;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Hispidulin inhibits proliferation and enhances chemosensitivity of gallbladder cancer cells by targeting HIF-1α

Keywords: Gallbladder cancer; Hispidulin; HIF-1α; P-gp; Chemosensitivity;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Redox-regulated fate of neural stem progenitor cells

Keywords: ARE; antioxidant response element; bHLH; basic helix-loop-helix; BMI1; B lymphoma Mo-MLV insertion region 1 homolog; CtBPs; C-terminal binding proteins; DLL4; delta-like protein 4; DVL; disheveled; DOUX; dual oxidases; ES; embryonic stem cells; EGFR; epid

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه