The Poly(ADP-ribose) polymerases (PARPs): New roles in intracellular transport
Keywords: PARP; PARG; Transport; Crm1; p53; NF-κB; HMGB1; AIF; KIF4; KLF8;
مقالات ISI (ترجمه نشده)
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Involvement of HMGB1 and RAGE in IL-1β-induced gingival inflammation
Keywords: IL-1β; Gingiva; HMGB1; RAGE;
Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models
Keywords: WFA; withaferin A; HMGB1; high mobility group box 1 protein; HUVEC; human umbilical vein endothelial cell; CAM; cell adhesion molecule; TNF-α; tumor necrosis factor-α; NF-κB; nuclear factor-κB; EC; endothelial cell; LPS; lipopolysaccharide; VCAM; vasc
Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models
Keywords: Lycopene; HMGB1; Inflammation; Vascular disease;
Tanshinone IIA sodium sulfonate facilitates endocytic HMGB1 uptake
Keywords: HMGB1; high mobility group box 1; LC3; microtubule-associated protein1 light chain 3; TSN-SS; tanshinone IIA sodium sulfonate; HMGB1; Macrophage; Endocytosis; Tanshinone; Autophagy;
Research ReportProtective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines
Keywords: CAT; Catalase; H2; Hydrogen gas; H2O2; Hydrogen peroxide; HMGB1; High-mobility group protein 1; HS; Hydrogen-rich saline; 8-iso-PGF2α; 8-iso-prostaglandin F2α; MCA; Middle cerebral artery; MDA; Malondialdehyde; OH; Hydroxyl radicals; pMCAO; Permanent mi
System xcâ regulates microglia and macrophage glutamate excitotoxicity in vivo
Keywords: CNS; central nervous system; LPS; lipopolysaccharide; OPC; oligodendrocyte progenitor cell; GSH; glutathione; TLR; toll-like receptor; NBQX; 2,3-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide; DAB; diaminobenzidine; DAPI; 4â²,6-diamidi
HMGB1 in vascular diseases: Its role in vascular inflammation and atherosclerosis
Keywords: HMGB1; RAGE; TLRs; Vasculitis; Atherosclerosis
The origin and properties of extracellular DNA: From PAMP to DAMP
Keywords: DNA; Anti-DNA; Systemic lupus erythematosus; Apoptosis; Immune complexes; HMGB1
Research ArticleProfound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats
Keywords: HCC; hepatocellular carcinoma; DEN; diethylnitrosamine; DSS; dextran sulfate sodium; PAMP; pathogen-associated molecular patterns; DAMP; damage-associated molecular patterns; HMGB1; high-mobility group box 1; TAL; tachypleus amebocyte lysate; Hepatocellul
Research ArticleMolecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity
Keywords: ALF; acute liver failure; ALI; acute liver injury; ALT; alanine aminotransferase; APAP; acetaminophen; DILI; drug-induced liver injury; HMGB1; High Mobility Group Box-1 protein; KCC; Kings College Criteria; K18; keratin-18; LFT; liver function test; NAC;
Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion
Keywords: Glycyrrhizin; HMGB1; MCAO; Neuroprotection; Anti-inflammation
2-Methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction
Keywords: 2-Methoxycinnamaldehyde; Inflammation; HMGB1; VCAM-1; Heme oxygenase-1; Ischemia; Reperfusion injury;
TNF-α induced secretion of HMGB1 from non-immune canine mammary epithelial cells (MTH53A)
Keywords: HMGB1; Secretion; Cytokines; Tumor; Canis familiaris
The Kupffer Cell Inhibition Exacerbates but Splenectomy Prevents Mortality in a Rat Septic Peritonitis Model
Keywords: sepsis; cytokine; heterogeneity; lung injury; splenectomy; HMGB1; Kupffer cell
Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and toll-like receptors in the adult prefrontal cortex
Keywords: AIE; adolescent intermittent ethanol; BEC; blood ethanol content; FC2; frontal cortex area 2; HMGB1; high-mobility group box 1; IHC; immunohistochemistry; IL; infralimbic cortex; +IR; immunoreactivity; LPS; lipopolysaccharide; OFC; orbitofrontal cortex; P
Toll-like receptors in chronic pain
Keywords: TLRs; Toll-like receptors; ERK; extracellular signal-regulated kinase; JNK; c jun N-terminal kinase; IL; interleukin; TNF-α; tumor necrosis factor-α; PGE2; prostaglandin E2; GLT1; glutamate transporter 1; GLAST; glutamate aspartate transporter; LPS; lip
Apicidin and Docetaxel Combination Treatment Drives CTCFL Expression and HMGB1 Release Acting as Potential Antitumor Immune Response Inducers in Metastatic Breast Cancer Cells
Keywords: CTCFL; CTCF-like protein; HDACi; histone deacetylase inhibitors; CT; cancer testis; CRT; calreticulin; HMGB1; high-mobility group box 1 protein; MHC I; major histocompatibility complex class I; DCs; dendritic cells; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-
PCA-ELISA: A sensitive method to quantify free and masked forms of HMGB1
Keywords: HMGB1; Interfering factors; ELISA; EMSA; Septic shock
Suppression of high-mobility group box-1 and receptor for advanced glycation end-product axis by polymyxin B-immobilized fiber hemoperfusion in septic shock patients
Keywords: HMGB1; sRAGE; Septic shock; Endotoxin; PMX-F;
DR396, an apoptotic DNase γ inhibitor, attenuates high mobility group box 1 release from apoptotic cells
Keywords: Apoptosis; DNA fragmentation; DNase γ; Inhibitor; HMGB1;
Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response
Keywords: BCA; bicinchoninic acid; HR; heart rate; H&E; hematoxylin-eosin; HMGB1; high-mobility group box 1; IL-6; interleukin 6; IS; infarct size; LAD; left anterior descending; LVEDP; left ventricular end-diastolic pressure; LVSP; left ventricular systolic pres
High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products
Keywords: HMGB1; High-mobility group box-1; LPS; lipopolysaccharide; LPS-RS; Rhodobacter sphaeroides lipopolysaccharide; RAGE; Receptor for Advanced Glycation End Products; NORT; novel object recognition test; TLE; temporal lobe epilepsy; TLR4; toll-like receptor 4
Expression of HMGB1 and HMGN2 in gingival tissues, GCF and PICF of periodontitis patients and peri-implantitis
Keywords: HMGB1; HMGN2; Periodontitis; Peri-implantitis;
CKD712, (S)-1-(α-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, inhibits the lipopolysaccharide-stimulated secretion of HMGB1 by inhibiting PI3K and classical protein kinase C
Keywords: CLP; cecum and ligation puncture; HMGB1; high mobility group box 1 protein; iNOS; inducible nitric oxide synthase; PBMo; peripheral blood monocytes; PDK-1; phosphoinositide-dependent kinase 1; PKC; protein kinase C; cPKC; classical PKC; Sepsis; Inflammati
The release of high mobility group box 1 in apoptosis is triggered by nucleosomal DNA fragmentation
Keywords: Nucleosomal DNA fragmentation; Apoptosis; HMGB1; CAD; DNase
Protective effect of Acanthopanax gracilistylus-extracted Acankoreanogenin A on mice with fulminant hepatitis
Keywords: Acankoreanogenin A; Fulminant hepatitis; Inflammatory cytokine; HMGB1
Production of recombinant human HMGB1 and anti-HMGB1 rabbit serum
Keywords: Recombinant; HMGB1; Protein purification; Anti-serum
Relationship Between HMGB1 and Tissue Protective Effects of HSP72 in a LPS-Induced Systemic Inflammation Model
Keywords: HSP72; lipopolysaccharide; acute inflammation; pulmonary; HMGB1
(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction
Keywords: CO; carbon monoxide; CLP; cecal ligation and puncture; ECR; methanol extract of Cyperus rotundus; HO-1; heme oxygenase-1; HMGB1; high mobility group box 1; LPS; lipopolysaccharide; iNOS; inducible nitric oxide synthase; NO; nitric oxide; PVDF; polyvinylid
EPCK1, a Vitamin C and E Analogue, Reduces Endotoxin-Induced Systemic Inflammation in Mice
Keywords: lipopolysaccharide; nitric oxide; HMGB1; liver injury; antioxidant; oxidative stress
High mobility group box 1 protein suppresses T cell-mediated immunity via CD11clowCD45RBhigh dendritic cell differentiation
Keywords: HMGB1; high mobility group box 1 protein; DC; dendritic cell; IL-4/10/12; interleukin-4/10/12; IFN-γ; interferon-γ; MLR; mixed lymphocyte reaction; High mobility group box 1 protein; Dendritic cell; CD11chighCD45RBlow DCs; CD11clowCD45RBhigh DCs; Immuni
ReviewToll-like receptors in inflammation of the central nervous system
Keywords: CNS; central nervous systems; COX-2; cyclooxygenase-2; DAMP; damage-associated molecular pattern; EAE; experimental autoimmune encephalomyelitis; HMGB1; high mobility group box 1; IL; interleukin; iNOS; inducible nitric oxide synthase; IRF; interferon reg
Macrophage activation by factors released from acetaminophen-injured hepatocytes: Potential role of HMGB1
Keywords: AA; acetaminophen; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â², 7â²-dichlorodihydro-fluorescein diacetate acetyl ester; COX; cyclooxygenase; DTPA; diethylene triamine pentaacetic acid; EGTA; ethylene glycol-bis(2-aminoethylether)-N,N,Nâ²,Nâ²-tetraacetic ac
HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption
Keywords: HMGB1; RAGE; Acute lung injury; Endothelium; MAP kinase; Hsp27;
Gabexate Mesilate Inhibits the Expression of HMGB1 in Lipopolysaccharide-Induced Acute Lung Injury
Keywords: gabexate mesilate; HMGB1; lipopolysaccharide; acute lung injury
The effect of biodegradable gelatin microspheres on the neuroprotective effects of high mobility group box 1 A box in the postischemic brain
Keywords: Gelatin microsphere; HMGB1; A box; Neuroprotection; Brain ischemia; MCAO
Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation
Keywords: HMGB1; cyclosporine A; FK506; rapamycin; astrocytes; ischemia; iNOS; COX-2
Toll-like receptor signaling in amyotrophic lateral sclerosis spinal cord tissue
Keywords: Toll-like receptors; HMGB1; ALS; spinal cord; glia; neurodegenerationALS, amyotrophic lateral sclerosis; ALS-lt, long-term survival >48 months; ALS-st, short-term survival <18 month; GFAP, glial fibrillary acidic protein; HMGB1, high mobility group box 1;
Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes
Keywords: Keratinocytes; house dust mite; caspase-1; IL-1β; IL-18; NLRP3; inflammasome; Dermatophagoides pteronyssinus; Der p 1; AD; Atopic dermatitis; ASC; Apoptosis-associated specklike protein containing a caspase-recruitment domain; E-64; Trans-epoxysuccinyl L
Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors
Keywords: HMGB1; Amphoterin; RAGE; Proteoglycan; Toll-like receptors; Cell migration
HMGB1, a potent proinflammatory cytokine in sepsis
Keywords: HMGB1; Inflammation; Sepsis; Septic shock; Cytokines
Sequential changes of Legionella antigens and bacterial load in the lungs and urines of a mouse model of pneumonia
Keywords: Legionella pneumophila; Antigen; LAMP; HMGB1
The CO-releasing molecule CORM-3 protects against articular degradation in the K/BxN serum transfer arthritis model
Keywords: CO-releasing molecule; CORM-3; HMGB1; K/BxN serum transfer arthritis; PGD2
Targeting HMGB1 in inflammation
Keywords: Cytokine; HMGB1; Inflammation; Immune response; Receptor
The role of HMGB1 in the pathogenesis of rheumatic disease
Keywords: HMGB1; Inflammation; Rheumatic diseases; Necrosis; Apoptosis; Therapy
HMGB1 attenuates anti-metastatic defence of the liver in colorectal cancer
Keywords: Colorectal cancer; Liver metastasis; HMGB1; Kupffer cell
Elevated expression of HMGB1 in squamous-cell carcinoma of the head and neck and its clinical significance
Keywords: Head and neck cancer; HMGB1; Squamous-cell carcinoma; Metastasis; Prognosis;
Moderate hypothermia suppresses jugular venous superoxide anion radical, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats
Keywords: CPA; cardiopulmonary arrest; ROS; reactive oxygen species; O2â·; superoxide anion radical; FBI/R; forebrain ischemia/reperfusion; HMGB1; high-mobility group box 1; MH; moderate hypothermia; ÎI; difference in O2-· current; Q; quantified partial value
High-mobility group box 1 and cancer
Keywords: HMGB1; Damage associated molecular pattern molecule [DAMP]; Autophagy; Cancer; Angiogenesis; Receptor for advanced glycation endproducts [RAGE]; TLR2; TLR4; CD24; TLR9; Hallmarks of cancer; Field effect; Inflammation