Keywords: هومووانیلیک اسید; Aβ; amyloid β; AADC; L-amino acid decarboxylase; ACC; Anterior cingulate cortex; AD; Alzheimer's disease; aMCI; Amnestic mild cognitive impairment; APP; Amyloid precursor protein; AR; Adrenergic receptor; ATMX; atomoxetine; BDNF; Brain-derived neurotrop
مقالات ISI هومووانیلیک اسید (ترجمه نشده)
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Prenatal vitamin D deficiency does not exacerbate behavioural impairments associated with prenatal ethanol exposure in juvenile male mice
Keywords: هومووانیلیک اسید; Juvenile mouse behaviour; Foetal alcohol exposure; Vitamin D deficiency; 25(OH)D; 25-hydroxyvitamin D (calcidiol); Aadc; aromatic L-amino acid decarboxylase; ADHD; attention deficit hyperactivity disorder; ASD; Autism spectrum disorder; COMT; comethyl tra
Evaluation of antiparkinson activity of PTUPB by measuring dopamine and its metabolites in Drosophila melanogaster: LC-MS/MS method development
Keywords: هومووانیلیک اسید; PD; Parkinson disease; DA; Dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; HVA; Homovanillic acid; BBB; blood brain barrier; sEH; soluble epoxide hydrolase; mEH; microsomal epoxide hydroxylases; COX-2; cyclooxygenase-2; ROS; reactive oxygen species; AA;
TREM2 overexpression attenuates neuroinflammation and protects dopaminergic neurons in experimental models of Parkinson's disease
Keywords: هومووانیلیک اسید; AD; Alzheimer's disease; CNS; central nervous system; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; ESI; electrospray interface; FTD; frontotemporal dementia; HPLC-MS/MS; high-performance liquid chromatography-tandem mass spectrometry; HVA; homovanilli
Comprehensive, robust, and sensitive UPLC-MS/MS analysis of free biogenic monoamines and their metabolites in urine
Keywords: هومووانیلیک اسید; EPI; epinephrine; NE; norepinephrine; DE; dopamine; MN; metanephrine; NMN; normetanephrine; 3-MT; 3-methoxytyramine; 5-HT; serotonin; 5-HIAA; 5-hydroxyindole-3-acetic acid; VMA; vanillylmandelic acid; HVA; homovanillic acid; MOPEGAL; 3-methoxy-4-hydroxyph
Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease
Keywords: هومووانیلیک اسید; 5-HT; serotonin, 6-OHDA, 6-hydroxydopamine; CDNF; cerebral dopamine neurotrophic factor; DA; dopamine; DBS; deep brain stimulation; DOPAC; 3,4-dihydroxyphenylacetic acid; GDNF; glial cell line-derived neurotrophic factor; HVA; homovanillic acid; IBOT; ibo
Relationship between serum homovanillic acid, DRD2 C957T (rs6277), and hDAT A559V (rs28364997) polymorphisms and developmental stuttering
Keywords: هومووانیلیک اسید; Stuttering; Dopamine; Homovanillic acid; DRD2 C957T;
Common gut microbial metabolites of dietary flavonoids exert potent protective activities in β-cells and skeletal muscle cells
Keywords: هومووانیلیک اسید; Hippuric acid; Homovanillic acid; 5-Phenylvaleric acid; (â)-Epicatechin; Insulin; Respiration;
Large neutral amino acid supplementation as an alternative to the phenylalanine-restricted diet in adults with phenylketonuria: evidence from adult Pah-enu2 mice
Keywords: هومووانیلیک اسید; 5-HIAA; 5-hydroxyindoleacetic acid; BBB; blood-brain barrier; HVA; homovanillic acid; LAT1; large neutral amino acid transporter type 1; Ile; isoleucine; LNAA; large neutral amino acid; Leu; leucine; Phe; phenylalanine; PKU; phenylketonuria; Trp; trypto
Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease
Keywords: هومووانیلیک اسید; α-Syn; alpha-Synuclein; h-α-Syn; transgenic human alpha-Synuclein; D1 receptor; dopamine receptor type 1; D2 receptor; dopamine receptor type 2; DA; dopamine; DAT; dopamine transporter; VMAT2; vesicular monoamine transporter 2; DOPAC; 3,4-dihydroxypheny
Memantine ameliorates depressive-like behaviors by regulating hippocampal cell proliferation and neuroprotection in olfactory bulbectomized mice
Keywords: هومووانیلیک اسید; Apoptosis; Cell proliferation; Depression; Emotional behavior; Olfactory bulbectomy; Neuroinflammation; ANOVA; analysis of variance; Bax; Bcl-2-associated protein X; Bcl-2; B cell lymphoma/leukemia gene 2; BDNF; brain-derived neurotrophic factor; BrdU; 5-
Multivariate pharmacokinetic/pharmacodynamic (PKPD) analysis with metabolomics shows multiple effects of remoxipride in rats
Keywords: هومووانیلیک اسید; AAAD; aromatic amino acid decarboxylase; AQC; 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate; ASCA; ANOVA Simultaneous Component Analysis; BCAA; branched chain amino acids; brainECF; brain extracellular fluid; CNS; central nervous system; D2R; dopamine D
Knockout of sodium pump α3 subunit gene (Atp1a3â/â) results in perinatal seizure and defective respiratory rhythm generation
Keywords: هومووانیلیک اسید; 3-MT; 3-methocytryptamine; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; 5-hydroxytryptamine; AHC; alternating hemiplegia of childhood; ATP1A3 or Atp1a3; gene for sodium pump α3 subunit of human or mouse, respectively; Atp1a3; homozygous knockout mice of Atp
Research PaperZonisamide attenuates lactacystin-induced parkinsonism in mice without affecting system xcâ
Keywords: هومووانیلیک اسید; 5HT; serotonin; 5HIAA; 5-hydroxyindoleacetic acid; 6-OHDA; 6-hydroxydopamine; DA; dopamine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; ECL; enhanced chemiluminescence; GSH; glutathione; HVA; homovanillic acid; i.p.; intraperitoneal;
Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice
Keywords: هومووانیلیک اسید; 3α-diol; 5α-androstane-3α, 17β-diol; 3β-diol; 5α-androstane-3β, 17β-diol; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DHEA; dehydroepiandrosterone; DHP; 5α-dihydroprogesterone; DHT; dihydrotestost
Involvement of serotonergic, noradrenergic and dopaminergic systems in the antidepressant-like effect of ginsenoside Rb1, a major active ingredient of Panax ginseng C.A. Meyer
Keywords: هومووانیلیک اسید; OFT; open-field test; TST; tail suspension test; FST; forced swim test; CUMS; chronic unpredicted mild stress; PCPA; p-Chlorophenylalanine; 5-HTP; 5-hydroxytryptophan; NE; noradrenergic; 5-HT; 5-hydroxytrylamine; 5-HIAA; 5-hydroxyindoleacetic acid; DA; do
Plasmalogen precursor mitigates striatal dopamine loss in MPTP mice
Keywords: هومووانیلیک اسید; AADC; aromatic acid decarboxylase; DA; dopamine; DAT; dopamine transporter; DHA; docosahexaenoic acid; DOPAC; 3,4-dihydroxyphenylacetic acid; 5-HIAA; 5-hydroxyindoleacetic acid; HPLC; high performance liquid chromatography; 5-HT; serotonin; [3H]-TBZ-OH; [
Xiaochaihutang attenuates depressive/anxiety-like behaviors of social isolation-reared mice by regulating monoaminergic system, neurogenesis and BDNF expression
Keywords: هومووانیلیک اسید; XCHT; Xiaochaihutang; SI; social isolation; TST; tail suspension test; FST; forced swimming test; OFT; open field test; EPM; elevated-plus maze; AT; intruder-induced aggression test; GLU; glutamic acid; GABA; γ-aminobutyric acid; 5-HT; 5-hydroxyptramine;
Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not
Keywords: هومووانیلیک اسید; SN; substantia nigra; DA; dopamine; NA; noradrenaline; 5-HT; 5-hydroxytryptamine; LED; light emitting diode; PD; Parkinson's disease; TH; tyrosine hydroxylase; 5-HIAA; 5-hydroxyindoleacetic acid; DOPAC; 3, 4-dihydroxyphenylacetic acid; HVA; homovanillic
Expanding the repertoire of L-DOPA's actions: A comprehensive review of its functional neurochemistry
Keywords: هومووانیلیک اسید; AADC; aromatic L amino acid decarboxylase; COMT; catechol-O-methyl-transferase; CSF; cerebrospinal fluid; 6-OHDA; 6-hydroxydopamine; DBH; dopamine β-hydroxylase; DOPAC; 3,4-dihydroxyphenylacetic acid; 3-MT; 3-methoxytyramine; DA; dopamine; DAT; dopamine
The role of system Xcâ in methamphetamine-induced dopaminergic neurotoxicity in mice
Keywords: هومووانیلیک اسید; Methamphetamine neurotoxicity; System Xcâ; xCT knockout mice; Glutamate-related toxicity; Oxidative damage; Striatum; ANOVA; analysis of variance; CNS; central nervous system; DA; dopamine; DCF; dichlorofluorescin; DCFH-DA; 2â²,7â²-dichlorofluorescin
BNN-20, a synthetic microneurotrophin, strongly protects dopaminergic neurons in the “weaver” mouse, a genetic model of dopamine-denervation, acting through the TrkB neurotrophin receptor
Keywords: هومووانیلیک اسید; Parkinson's-disease; Microneurotrophin; Neuroprotection; TrkB-receptor-signaling; NGL (NF-κB; GFP.Luc)-mice; Arg1; Arginase; BBB; blood-brain-barrier; BDNF; Brain-Derived Neutrotrophic Factor; BNN-20; 17-beta-spiro-[5-androsten-17,2'-oxiran]-3beta-ol; CS
Associations between a locus downstream DRD1 gene and cerebrospinal fluid dopamine metabolite concentrations in psychosis
Keywords: هومووانیلیک اسید; HVA; homovanillic acid; DRD2; dopamine receptor D2 gen; CSF; cerebrospinal fluid; CNS; central nervous system; DRD1; dopamine receptor D1 gene; DRD3; dopamine receptor D3 gene; DRD4; dopamine receptor D4 gene; DRD5; dopamine receptor D5 gene; SNPs; single
3-O-methyldopa levels in newborns: Result of newborn screening for aromatic l-amino-acid decarboxylase deficiency
Keywords: هومووانیلیک اسید; 3-OMD; 3-O-methyldopa; AADC; Aromatic l-amino acid decarboxylase; CI; confidence interval; DBS; dried blood spots; GA; gestational age; HIAA; 5-hydroxyindolacetic acid; HVA; homovanillic acid; LC-MS/MS; Liquid chromatography-tandem mass spectrometry; OGC;
The influence of n-3 fatty acids on maternal behavior and brain monoamines in the perinatal period
Keywords: هومووانیلیک اسید; n-3 Def; n-3 fatty acid deficiency; n-3 Adq; n-3 fatty acid adequacy; ARA; arachidonic acid, 20:4n-6; DHA; docosahexaenoic acid, 22:6n-3; GD; gestational day; PD; postpartum day; 5-HT; serotonin, 5-hydroxytryptamine; 5-HIAA; 5-hydroxyindole acetic acid; N
Baicalein inhibits α-synuclein oligomer formation and prevents progression of α-synuclein accumulation in a rotenone mouse model of Parkinson's disease
Keywords: هومووانیلیک اسید; PD; Parkinson disease; α-syn; α-synuclein; SN; substantia nigra; LBs; Lewy bodies; PFA; paraformaldehyde; TH; tyrosine hydroxylase; PBS; phosphate buffered saline; ChAT; choline acetyltransferase; HPLC; high performance liquid chromatography; DA; dopami
Anti-depressant effects of Gastrodia elata Blume and its compounds gastrodin and 4-hydroxybenzyl alcohol, via the monoaminergic system and neuronal cytoskeletal remodeling
Keywords: هومووانیلیک اسید; WGE; water extracts of Gastrodia elata Bl.; GAS; gastrodin; HBA; 4-hydroxybenzyl alcohol; HB; 4-hydroxybenzyl aldehyde; VAN; vanillin; OFT; open field test; FST; forced swimming test; MDD; major depression disorder; 5-HT; serotonin; 5-HIAA; 5-hydroxyindol
An optimized method for neurotransmitters and their metabolites analysis in mouse hypothalamus by high performance liquid chromatography-Q Exactive hybrid quadrupole-orbitrap high-resolution accurate mass spectrometry
Keywords: هومووانیلیک اسید; 5-HIAA; 5-hydroxyindole-3-acetic acid; 5-HT; 5-hydroxytryptamine; 5-HTP; 5-hydroxytryptophan; CA; caffeic acid; CV; coefficient of variation; DA; dopamine; DNS-Cl; dansyl chloride; DOPAC; 3,4-dihydroxyphenylacetic acid; E; epinephrine; GABA; γ-aminobutyr
Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate
Keywords: هومووانیلیک اسید; CPu; caudate putamen; DA; dopamine; DAergic; dopaminergic; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; HVA; homovanillic acid; NSDA; nigrostriatal dopaminergic; SN; substantia nigra; TH; tyrosine hydroxylase; TP; testosterone propion
Impact of LC-MS/MS on the laboratory diagnosis of catecholamine-producing tumors
Keywords: هومووانیلیک اسید; Mass spectrometry; Pheochromocytoma; Paraganglioma; Neuroblastoma; Normetanephrine; Metanephrine; Methoxytyramine; Norepinephrine; Epinephrine; Homovanillic acid, vanillymandelic acid; LC-MS/MS; liquid chromatography with tandem mass spectrometry; LC-ECD;
Effects of (â)-sesamin on motor and memory deficits in an MPTP-lesioned mouse model of Parkinson's disease treated with l-DOPA
Keywords: هومووانیلیک اسید; 6-OHDA; 6-hydroxydopamine; CREB; cyclic AMP-response element binding protein cyclic AMP; DOPAC; 3,4-dihydroxyphenylacetic acid; Epac; exchange protein activation by cAMP; ERK; extracellular signal-regulated kinase; HVA; homovanillic acid; JNK; c-Jun N-ter
Research reportVariability in the effect of antidepressants upon Wfs1-deficient mice is dependent on the drugs' mechanism of actions
Keywords: هومووانیلیک اسید; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; DA; dopamine; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; HVA; homovanillic acid; NA; noradrenaline; NMDA; N-methyl-d-aspartate; SERT; serotonin transporter; SSRI; selective serotonin r
Increased levels of brain serotonin correlated with MMP-9 activity and IL-4 levels resulted in severe experimental autoimmune encephalomyelitis (EAE) in obese mice
Keywords: هومووانیلیک اسید; 5-HIAA; 5-hydroxyindole acetic acid; 5-HT; 5-hydroxytryptamine, serotonin; AMCS; average mean clinical score; AUC; area under the curve; DA; dopamine; DHBA; 3,4-dihydroxybenzylamine; DOPAC; 3,4-dihydroxyphenyl acetic acid; EAE; experimental autoimmune enc
LC/MS-based metabolomics strategy to assess the amelioration effects of ginseng total saponins on memory deficiency induced by simulated microgravity
Keywords: هومووانیلیک اسید; Ach; acetylcholine; AD; Alzheimer's disease; Asn; asparagine; Asp; aspartic acid; BC; behavioral research control group; BH; behavioral research HU group; BHG; behavioral research HU plus GTS treatment group; CORT; corticosterone; DA; dopamine; DHBA; dihy
Aromatic l-amino acid decarboxylase deficiency diagnosed by clinical metabolomic profiling of plasma
Keywords: هومووانیلیک اسید; 3-MT; 3-methoxytyrosine; M-MTS; 3-methoxytyramine sulfate; 3-O-MD; 3-O-methyldopa; 5-HTP; 5-hydroxytryptophan; AADC; aromatic l-amino acid decarboxylase deficiency; COMT; catechol-O-methyl transferase; CSF; cerebrospinal fluid; HVA; homovanillic acid; 5-H
Altered histamine neurotransmission in HPRT-deficient mice
Keywords: هومووانیلیک اسید; 1-MH; 1-methylhistamine; 1-MI4AA; 1-methylimidazole-4-acetic acid; 3-MT; 3-methoxytyramine; d4-dopamine; 2-(3,4-dihydroxyphenyl)ethyl-1,1,2,2-d4-amine HCl; d4-histamine; histamine-d4 diHCl; d5-DOPAC; 3,4-dihydroxyphenylacetic acid (ring-d3,2,2-d2); d6-nor
Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits
Keywords: هومووانیلیک اسید; DAT; dopamine transporter; PD; Parkinson's disease; DAT-tg; dopamine transporter over-expressing transgenic; DAT-KO; dopamine transporter knock-out; VMAT2; vesicular monoamine transporter 2; VMAT2-kd; vesicular monoamine transporter 2 knock-down; MPTP; 1-
Vitamin D regulates tyrosine hydroxylase expression: N-cadherin a possible mediator
Keywords: هومووانیلیک اسید; BSA; bovine serum albumin; DOPAC; dihydroxyphenylacetic acid; DVD; developmental vitamin D; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GDNF; glial-derived neurotrophic factor; HPLC; high-pressure liquid chromatography; HVA; homovanillic acid; PBS; p
Increased brain bio-distribution and chemical stability and decreased immunogenicity of an engineered variant of GDNF
Keywords: هومووانیلیک اسید; 6-OHDA; 6-Hydroxy-dopamine; BBB; Blood-brain-barrier; CEX; Cation Exchange chromatography; CHO; Chinese Hamster Ovary; DOPAC; Dihydroxyphenylacetic acid; Dopa; 3,4-dihydroxyphenylalanine; DA; Dopamine; ECM; Extracellular matrix; GDNF; Glial cell line-de
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo
Keywords: هومووانیلیک اسید; 6-OHDA; 6-hydroxydopamine; AAV; adeno-associated viral vector; Bcl-2; B-cell lymphoma 2; CNS; central nervous system; ctl; contralateral; DAPI; 4â²,6-diamidino-2-phenylindole; DIV; day in vitro; DOPAC; 3,4-dihydroxyphenylacetic acid; EGFP; enhanced green
Androgen metabolites impact CSF amines and axonal serotonin via MAO-A and -B in male macaques
Keywords: هومووانیلیک اسید; 5HIAA; 5-hydroxyindoleacetic acid; ANOVA; analysis of variance; AR; androgen receptors; CSF; cerebrospinal fluid; DHT; dihydrotestosterone; ER; estrogen receptors; FLUT; flutamide; HVA; homovanillic acid; IHC; immunohistochemistry; ISH; in situ hybridizat
Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway
Keywords: هومووانیلیک اسید; 6-OHDA; 6-hydroxydopamine; ARE; antioxidant response element; BSA; bovine serum albumin; Cyt C; cytochrome c; DA; dopamine; DAPI; 4â²,6-diamidino-2-phenylindole; DCFH-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; DOPAC; dih
Research ReportThe preferential nNOS inhibitor 7-nitroindazole and the non-selective one NG-nitro-l-arginine methyl ester administered alone or jointly with l-DOPA differentially affect motor behavior and monoamine metabolism in sham-operated and 6-OHDA-l
Keywords: هومووانیلیک اسید; ANOVA; analysis of variance; DA; dopamine; DOPAC; 3,4-dihydroxyphenylacetic acid; HPLC; high-pressure liquid chromatography; 5-HT; serotonin; 5-HIAA; 5-hydroxyindoleacetic acid; 6-OHDA; 6-hydroxydopamine hydrochloride; HVA; homovanillic acid; l-NAME; NG-n
Autotaxin, a secreted lysophospholipase D, as a promising therapeutic target in chronic inflammation and cancer
Keywords: هومووانیلیک اسید; ABTS; 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); AML; acute myeloid leukemia; ApnA; diadenosine polyphosphates; ATP; adenosine-5â²-triphosphate; ATX; autotaxin; BALF; bronchoalveolar lavage fluid; bis-pNPP; bis(p-nitrophenyl) phosphate; BLM
Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity
Keywords: هومووانیلیک اسید; 6-OHDA; 6-hydroxydopamine; AD; Alzheimer's disease; ARE; antioxidant response elements; DA; dopamine; DMF; dimethyl fumarate; DOPAC; dihydroxyphenylacetic acid; GCLC; glutathione cysteine ligase regulatory subunit; GCLM; glutathione cysteine ligase modu
Long-Term Follow-Up Results of the Observation Program for Neuroblastoma Detected at 6-Month Mass Screening
Keywords: هومووانیلیک اسید; HVA; Homovanillic acid; MRI; Magnetic resonance imaging; MS; Mass screening; NBL; Neuroblastoma; VMA; Vanillylmandelic acid;
Effects of ultrafine diesel exhaust particles on oxidative stress generation and dopamine metabolism in PC-12 cells
Keywords: هومووانیلیک اسید; Diesel exhaust particles; Oxidative stress; Dopamine; PC-12 cells; Neurotoxicity; DEPs; diesel exhaust particles; DOPAC; dihydroxyphenylacetic acid; HVA; homovanillic acid; PM; particulate matter; DA; dopamine; HPLC; high performance liquid chromatography
Shock/sepsis/trauma/critical careSepsis-induced changes in behavioral stereotypy in rats; involvement of tumor necrosis factor-alpha, oxidative stress, and dopamine turnover
Keywords: هومووانیلیک اسید; Sepsis; stereotypy; TNF-α; oxidative stress; homovanillic acid; sepsis-associated encephalopathy;
Subthalamotomy-induced changes in dopamine receptors in parkinsonian monkeys
Keywords: هومووانیلیک اسید; 6-OHDA; 6-hydroxydopamine; DA; dopamine; DAT; dopamine transporter; DL; dorsolateral; DM; dorsomedial; DOPAC; 3,4-dihydroxyphenylacetic acid; GPe; globus pallidus pars externa; GPi; globus pallidus pars interna; HFS; high-frequency stimulation; HPLC; high
Anxiety- and depression-like phenotype of hph-1 mice deficient in tetrahydrobiopterin
Keywords: هومووانیلیک اسید; BH4; tetrahydrobiopterin; NO; nitric oxide; NOS; nitric oxide synthase; GTP-CH1; guanosine triphosphate cyclohydrolase 1; DRD; DOPA-responsive dystonia; hph-1; hyperphenylalaninemia 1; WT; wild-type; hph; homozygous hph-1; DOPAC; deuterium-labelled 3,4-di