دانلود مقالات ISI درباره Hts + ترجمه فارسی

Benzimidazole-core as an antimycobacterial agent

Keywords: AIDS; acquired immunodeficiency syndrome; DNA; deoxyribonucleic acid; EMB; ethambuthol; GI; growth inhibition; HIV; human immunodeficiency virus; HTS; high throughput screening; INH; isoniazid; LTBI; latent tuberculosis infection; MABA; micro plate alamar

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Fluorescence-based assay for polyprenyl phosphate-GlcNAc-1-phosphate transferase (WecA) and identification of novel antimycobacterial WecA inhibitors

Keywords: Prenyl-phosphate-GlcNAc-1-phosphate transferase; WecA; Bacterial phosphotransferases; Mycobacterium tuberculosis; Fluorescence-based assay; HTS; WecA inhibitors

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Patient-specific hiPSC bioprocessing for drug screening: Bioprocess economics and optimisation

Keywords: COG; cost of goods; CTS; CompacT SelecTTM automated cell culture machine; FCI; fixed capital investment; hPSC; human pluripotent stem cell; HTS; high throughput screening; iPSC; induced pluripotent stem cell; PCA; patch-clamp analysis; NCE; novel chemical

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation

Keywords: Comprehensive in vitro Proarrhythmia Assay (CiPA); Field potential data sampling and analysis; Induced pluripotent cell cardiomyocytes (hiPSC-CMs); Multi electrode array (MEA); Patch clamp technologies; Pending issues and solutions; Validation; Voltage se

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Progress and prospects on DENV protease inhibitors

Keywords: Dengue; NS2B-NS3 protease; Proteolytic mechanism; Peptide inhibitors; Peptide conjugates; Small molecule inhibitors; Natural products; HTS; HTVS;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Prise en charge des léiomyomes utérins

Keywords: Myoma; leiomyoma; fibroid; myomectomy; uterine artery embolization; hysterectomy; heavy menstrual bleeding; menorrhagia; AAGL; American Association of Gynecologic Laparoscopists; AE; ablation de l'endomètre; ANET; acétate de noréthindrone; AUP; acétat

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of NF-κB inhibitors following Shenfu injection and bioactivity-integrated UPLC/Q-TOF-MS and screening for related anti-inflammatory targets in vitro and in silico

Keywords: BMC; Benzoyl-mesaconine; CAD; Coronary artery disease; CHD; Coronary heart disease; DEX; Dexamethasone; DMEM; Dulbecco's modified Eagle's Medium; ELISA; Enzyme-linked immunosorbent assay; ESI; Electrospray ionization; FBS; Fetal bovine serum; FUZ; Fuzil

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2016 سفارش ترجمه

Advancements in zebrafish applications for 21st century toxicology

Keywords: CRISPR; Clustered, regularly interspaced, short palindromic repeats; Dpf; Days post fertilization; DSB; Double strand break; Hpf; Hours post fertilization; HSC; Hematopoietic stem cell; HTS; High-throughput screen; KO; Knockout; MO; Morpholino oligonucleo

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Bioluminescent kinase strips: A novel approach to targeted and flexible kinase inhibitor profiling

Keywords: Kinase profiling; Bioluminescence; ADP detection; Selectivity profiles; Kinase assay; Kinase inhibitor; PTM; post-translational modification; FDA; U.S. Food and Drug Administration; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; TK; tyrosine kinase

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Nitrobenzofurazan derivatives of N′-hydroxyamidines as potent inhibitors of indoleamine-2,3-dioxygenase 1

Keywords: N′-hydroxyamidines; Mechanism-based drug design; IDO1 inhibition; High selectivity; Low cytotoxicity; IDO1; indoleamine 2,3-dioxygenase 1; TDO; tryptophan 2,3-dioxygenase; L-Trp; L-tryptophan; HTS; High throughput screening; UV-Vis; ultraviolet-visi

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

DNA repair targeted therapy: The past or future of cancer treatment?

Keywords: DNA damage; DNA repair; Cancer; Radiation; Replication protein A; NER; nucleotide excision repair; MMR; DNA mismatch repair; BER; base excision repair; HDR; homology directed repair; FA; Fanconi anemia; HR; homologous recombination; DDR; DNA damage respon

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2016 سفارش ترجمه

Heat transfer from Ni-W tapes in liquid nitrogen at different orientations in the field of gravity

Keywords: Heat transfer; Liquid nitrogen; HTS; Boiling regime; Ni-W tapes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular, serological and in vitro culture-based characterization of Bourbon virus, a newly described human pathogen of the genus Thogotovirus

Keywords: HTS; high throughput sequencing; BRBV; Bourbon virus; CDS; Centers for Disease Control and Prevention; RT-PCR; reverse transcription polymerase chain reaction; ORF; open reading frame; NJ; neighbor joining; PFU; plaque forming unit; IP; intraperitoneal; I

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Application of spray deposition techniques for fabrication of Sm-doped CeO2 thin films on biaxially textured Ni-W substrate

Keywords: Solid thin films; HTS; Buffer layer; Cerium Oxide;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of Bacillus anthracis PurE inhibitors with antimicrobial activity

Keywords: A260; UV absorbance at 260 nm; AIR; 5-amino-imidazole ribonucleotide; Ba; Bacillus anthracis (ΔANR strain); CAIR; 4-carboxy-amino-imidazole ribonucleotide; CD; circular dichroism; DMSO; dimethyl sulfoxide; E. coli ΔTolC; E. coli efflux pump knockout st

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

High-purity H2 production with CO2 capture based on coal gasification

Keywords: H2 production; Low-temperature CO2 capture; Coal gasification; H2 liquefaction; Pd-alloy membranes; HRF; hydrogen recovery factor; HTS; high temperature shift; IGCC; integrated gasification combined cycle; IRCC; integrated reforming combined cycle; LH2; l

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Therapeutic targets in the Wnt signaling pathway: Feasibility of targeting TNIK in colorectal cancer

Keywords: Colorectal cancer; Cancer stem cell; Wnt signaling; Traf2- and Nck-interacting kinase (TNIK); Molecular targeting therapy; ABC; ATP-binding cassette; APC; adenomatous polyposis coli; CBP; cAMP response element binding protein (CREB)-binding protein; CK; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

A Genome-Wide CRISPR Library for High-Throughput Genetic Screening in Drosophila Cells

Keywords: CRISPR/Cas9; Genome-wide library; Drosophila; Cas9; CRISPR associated protein 9; CRISPR; clustered regularly interspaced short palindromic repeat; HTS; high throughput sequencing; sgRNA; single guide RNA;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

ReviewEmerging DNA-based technologies to characterize food ecosystems

Keywords: Biotransformation; DNA barcoding; Food traceability; Food microbiota; High Throughput Sequencing; HTS;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Discovery of HCV NS5B thumb site I inhibitors: Core-refining from benzimidazole to indole scaffold

Keywords: HCV; RdRp; Thumb site I; Indole; Anti-viral; Heterocycle; HCV; hepatitis C virus; RdRp; RNA-depended-RNA-polymerase; WHO; World Health Organization; HCC; hepatocellular carcinoma; SOC; standard of care; PEG-IFN-α; pegalated α-interferon; RVB; Ribavi

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Development of fluorescent peptide substrates and assays for the key autophagy-initiating cysteine protease enzyme, ATG4B

Keywords: VWBVATUTVWMVIR-LJAQVGFWSA-N; ATG4B; autophagin 1; FRET; fluorescence resonance energy transfer; HTS; high throughput screening; LC3B; microtubule-associated protein 1 A/B light chain 3B; NEM; N-ethylmaleimide; LC-MS; liquid chromatography coupled mass s

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9

Keywords: 3-BrPA; 3 bromopyruvate; AOP; adverse outcome pathway; ARF4; ADP-ribosylation factor 4; BFA; brefeldin A; BT; 1,2,4-benzenetriol; CML; chronic myeloid leukemia; COSMID; CRISPR off-target sites with mismatches, insertions, and deletions; CRISPR-Cas9; clust

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIα targeting the ATP binding site

Keywords: AMP-PNP-5′; adenylyl-β,γ-imidodiphosphate; AUC; area under the receiver operating characteristic curve; DMSO; dimethyl sulfoxide; EF; enrichment factor; Fnorm; normalized fluorescence [‰] (per mill); GA; genetic algorithm; GHKL; Gyrase; Hsp90; histi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Integration of membrane technology into hydrogen production plants with CO2 capture: An economic performance assessment study

Keywords: ASU; air separation unit; CCS; carbon capture and sequestration; CPI; Consumer Price Index; CMR; catalytic membrane reactor; ENPV; expected net present value; FCI; fixed capital ınvestment; GPV; gross present value; HTS; high temperature shift; HP; hydro

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

T-cell receptor diversity is selectively skewed in T-cell populations of patients with Wiskott-Aldrich syndrome

Keywords: Wiskott-Aldrich syndrome; T-cell receptor repertoire diversity; high-throughput sequencing; CDR3; Complementarity-determining region 3; D50; Diversity 50; Ds; Simpson index of diversity; H′; Shannon-Wiener index; HTS; High-throughput sequencing; PE; Phy

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

(Q)SAR modelling of nanomaterial toxicity: A critical review

Keywords: AES; Auger electron spectroscopy; AFM; atomic force microscopy; ANNs; artificial neural networks; APO or Apop.; apoptosis; ATP; adenosine triphosphate (ATP); BET; Brunauer-Emmett-Teller; BSAI; biological surface adsorption index; CNTs; carbon nanotube

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

From transcriptomic to protein level changes in TDP-43 and FUS loss-of-function cell models

Keywords: RBPs; RNA-binding proteins; ALS; amyotrophic lateral sclerosis; FTD; frontotemporal dementia; HTS; high-throughput screening; F.C.; fold change; S.I.; splicing index; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; WB; Western blot; TDP-

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2015 سفارش ترجمه

Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR

Keywords: acetyl-CoA; acetyl coenzyme A; ALARM NMR; a La assay to detect reactive molecules by nuclear magnetic resonance; Asf1; anti-silencing function 1; AZ; AstraZeneca; BME; β-mercaptoethanol; BSA; bovine serum albumin; CoA; coenzyme A; CPM; N-[4-(7-diethylami

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2015 سفارش ترجمه

2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitors

Keywords: RSK; Kinase; Heterocycle; Benzoxazole; HTS;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Present status and future trends of R&D for HTS rotational machines in Japan

Keywords: Rotating machine; HTS; Ship propulsion; Vehicle application; Industrial application

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

An ultrasensitive system for measuring the USPs and OTULIN activity using Nanoluc as a reporter

Keywords: Nluc; Nanoluc; AMC; 7-amino-4-methylcoumarin; DTT; dithiothreitol; DMSO; dimethylsulfoxide; HTS; high-throughput screening; USP; ubiquitin-specific protease; GST; glutathione s-transferase; EGFP; enhanced green fluorescence protein; FRET; fluorescence res

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor

Keywords: PAK4; HTS; Protein kinase; Cancer; Drug discovery; X-ray crystallography

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Improved resolution of bacteria by high throughput sequence analysis of the rRNA internal transcribed spacer

Keywords: ARISA; automated ribosomal intergenic spacer analysis; HTS; high throughput sequencing; ITS; internal transcribed spacer; LSU; large subunit; OTU; operational taxonomic unit; PCoA; principle coordinates analysis; RISA; ribosomal intergenic spacer analysis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Diarylacylhydrazones: Clostridium-selective antibacterials with activity against stationary-phase cells

Keywords: CCCP; carbonyl cyanide m-chlorophenylhydrazone; CDAD; Clostridium difficile-associated diarrhoea; CDI; Clostridium difficile infection; DACC; Data Analysis and Coordination Centre; 2,4-DNP; 2,4-dinitrophenol; DMSO; dimethyl sulfoxide; FDA; US Food and Dru

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Correlation of solubility of hexamethylene-1,6-bisthiosulphate disodium salt dihydrate versus dielectric constants of water + ethanol mixtures

Keywords: HTS; Solubility; Dissolution enthalpy; Dissolution entropy; Dielectric constant

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

A new combination approach of CI jet and QESD to formulate pH-susceptible amorphous solid dispersions

Keywords: ASDs; Amorphous solid dispersions; BCS; Biopharmaceutics classification system; BI; Boehringer Ingelheim Pharmaceuticals; CIJ; Confined impinging jet; CQAs; Critical quality attributes; DCM; Dicholoromethane; HP-55; Hydroxypropyl methylcellulose phthalate

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Practical design and operating characteristic analysis of a 10 kW HTS DC induction heating machine

Keywords: Cryogenic; FEM; HTS; Induction heating; No insulation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Limitations and recommendations for successful DNA extraction from forensic soil samples: A review

Keywords: Soil; DNA; Extraction; Forensic; Metagenomics; HTS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agents

Keywords: SK; streptokinase; GAS; Group A Streptococcus; HTS; high-throughput screen; SAR; structure-activity relationship; TPSA; topological polar surface area; c Log P; logarithm of the calculated octanol-water partition coefficient; LDA; lithium diisopropy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Improving the apo-state detergent stability of NTS1 with CHESS for pharmacological and structural studies

Keywords: GPCR; G protein-coupled receptor; IMP; integral membrane protein; CHESS; cellular high-throughput encapsulation solubilization and screening; NT; neurotensin peptide; FACS; fluorescence-activated cell sorting; EDTA; ethylenediaminetetraacetic acid; DDM; n

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Statistical parametric speech synthesis for Ibibio

Keywords: Speech synthesis; Ibibio; Low-resource languages; HTS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Screening-based discovery of Aspergillus fumigatus plant-type chitinase inhibitors

Keywords: HTS; high-throughput screen/screening; GlcNAc; N-acetylglucosamine; AfChiA1; Aspergillus fumigatus chitinase A1; ScCTS1; Saccharomyces cerevisiae chitinase 1; AfChiB; Aspergillus fumigatus chitinase B1; AMCase; acidic mammalian chitinase; HsCHT; Homo sapi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold

Keywords: AD; Alzheimer's disease; ANK; ankyrin repeat domain; ARM; armadillo repeat domain; AUC; area under the curve; BA; brain availability; BBB; blood brain barrier; BCRP; breast cancer related protein; BI; brain impairment; CSD; Cambridge Structural Database

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Bioengineering 3D environments for cancer models

Keywords: EMT; epithelial-mesenchymal transition; ECM; extracellular matrix; 2D; two-dimensional; 3D; three-dimensional; PEG; polyethylene glycol; PLG; poly(lactide-co-glycolide); PLA; polylactic acid; RGD; arginine-glycine-aspartate peptide sequence; MMPs; m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Applications of NMR screening techniques to the pharmaceutical target Checkpoint kinase 1

Keywords: AEBSF; 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride; Chk1; Checkpoint kinase 1; DIRECTION; Difference of Inversion REcovery rate with and without Target IrradiatiON; DSBs; double strand breaks; HEPES; 4-(2-HydroxyEthyl)-1-PiperazineEthaneSulfoni

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel drug scaffolds for inhibition of SARS-CoV 3-Chymotrypsin-like protease using virtual and high-throughput screenings

Keywords: SARS-CoV; Severe Acute Respiratory Syndrome coronavirus; 3CLpro; 3 Chymotrypsin-like cysteine protease; MD; molecular dynamics; VS; virtual screening; CSM; computational solvent mapping; ROC; receiver operating characteristic; RMSD; root mean square devia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Developing zebrafish models relevant to PTSD and other trauma- and stressor-related disorders

Keywords: BDNF; brain-derived neurotrophic factor; COMT; catechol-O-methyltransferase; CRF; corticotropin releasing factor; HTS; high-throughput screens; HPA; hypothalamic-pituitary-adrenal; HPI; hypothalamic-pituitary-interrenal; LSD; lysergic acid diethyl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

HTS and HTSn: New shape descriptors based on Hough transform statistics

Keywords: HTS; HTSn; Image analysis; Shape analysis; Hough transform; Content-based image retrieval; Optical character recognition

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427

Keywords: BAC; Bacterial Artificial Chromosome; BES; bloodstream-form VSG expression site; BF; bloodstream form of the T. brucei life cycle; CDS; coding sequence; GPI; glycosyl phosphatidyl inositol; HTS; high-throughput sequencing; IC; intermediate-sized chromosom

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Analysis and HMM-based synthesis of hypo and hyperarticulated speech

Keywords: Speech synthesis; HTS; Speech analysis; Expressive speech; Speaking style adaptation; Voice quality; Speech intelligibility;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2014 سفارش ترجمه