دانلود مقالات ISI درباره کلیه جنین انسان + ترجمه فارسی

Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Keywords: کلیه جنین انسان; OCT1; Organic Cation Transporter 1; hOCT1; human OCT1; HEK; Human Embryonic Kidney; EV; empty vector; MPP+; 1-methyl-4-phenylpyridinium; TEA; tetraethylammonium; CCF; competitive counter flow; TMD; transmembrane domains; CHARMm; Chemistry at Harvard Macro

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroanatomical distribution and function of the vasopressin V1B receptor in the rat brain deciphered using specific fluorescent ligands

Keywords: کلیه جنین انسان; ACTH; adrenocorticotropic hormone; AVP; arginine8 vasopressin; AC; adenylyl cyclase; BSA; bovine serum albumin; CaMKII; calmoduline-dependent serine/threonine kinase II; CHO; chinese hamster ovary; DG; dentate gyrus; DMEM; Dulbecco's modified Eagles'

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

On the G protein-coupling selectivity of the native A2B adenosine receptor

Keywords: کلیه جنین انسان; BAY60-6583; 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; cAMP; 3′,5′-cyclic adenosine monophosphate; CE3F4; 5,7-dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde; CGS21680; 2-[p-(2-carboxyethy

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines

Keywords: کلیه جنین انسان; Alprenolol (Pubchem CID: 2119); CGP 12177 (Pubchem CID: 2687); CGP 20712A (Pubchem CID: 2685); Cimaterol (Pubchem CID: 2755); Furimazine (Pubchem CID: 219083); Hoechst 33342 (Pubchem CID: 1464); IBMX (Pubchem CID: 3758); ICI 118551 (Pubchem CID: 5484725);

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Tools and drugs for uracil nucleotide-activated P2Y receptors

Keywords: کلیه جنین انسان; ADP; Adenosine 5′-diphosphate; AP4A; P1,P4-Di(adenosine-5′)-tetraphosphate; AR; Adenosine receptor; AR-C118925; 5-{[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl}-N-(1H-tetrazol-5-yl)-2-furancarbo

دانلود رایگان متن کامل مقاله ISI 193 صفحه سال انتشار : 2018 سفارش ترجمه

Attachment of a 'molecular spring' restores drug-stimulated ATPase activity to P-glycoprotein lacking both Q loop glutamines

Keywords: کلیه جنین انسان; P-glycoprotein; ABC protein; Disulfide cross-linking; Molecular spring; Drug-stimulated ATPase activity; ABC; ATP-binding cassette; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; human embryonic kidney; TM; transmembrane; TMD; transmembrane do

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Down-regulation of Kir2.6 channel by c-termini mutation D252N and its association with the susceptibility to Thyrotoxic Periodic Paralysis

Keywords: کلیه جنین انسان; EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; HEK; Human embryonic kidney; Hepes; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; TPP; Thyrotoxic Periodic Paralysis; TREs; thyroid hormone response elements; TSH; t

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Original articlePharmacological effects of β-d-mannuronic acid (M2000) on miR-146a, IRAK1, TRAF6 and NF-κB gene expression, as target molecules in inflammatory reactions

Keywords: کلیه جنین انسان; ANOVA; analysis of variance; CCL-8; chemokine (C-C motif) ligand 8; CO2; carbon dioxide; FADD; fas-associated protein with death domain; HEK; human embryonic kidney; IRAK1; interleukin-1 receptor-associated kinase 1; IRF5; interferon regulatory factor 5;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperDetection of potassium channel KIR4.1 antibodies in Multiple Sclerosis patients

Keywords: کلیه جنین انسان; CRESM; Regional Referring Multiple Sclerosis Centre; NICO; Neuroscience Institute Cavalieri Ottolenghi; KIR4.1; inward-rectifying potassium channel 4.1; MS; multiple sclerosis; LG-KIR4.1; lower-glycosylated KIR4.1; HEK; human embryonic kidney; ELISA; enzy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

A short cross-linker activates human P-glycoprotein missing a catalytic carboxylate

Keywords: کلیه جنین انسان; 1, 10-Phenanthroline (PubChemSID: 24278); Cyclosporine A (PubChemCID: 5284373); Verapamil hydrochloride (PubChemCID: 62969); Vinblastine (PubChemCID: 241903); n-dodecyl-β-D-maltoside (PubChemCID: 114880); ABC; ATP-binding cassette; P-gp; P-glycoprotein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The binding orientation of epibatidine at α7 nACh receptors

Keywords: کلیه جنین انسان; Cys-loop; Ion channel; Radioligand; Epibatidine; Agonist; α7 nACh; Nicotinic; Receptor; AChBP; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI− cells

Keywords: کلیه جنین انسان; NKR-P1; CD161; klrb1; NK cells; HEK293; LLT1; CTL; C-type lectin-like; GnTI−; N-acetylglucosaminyltransferase I negative; HEK; human embryonic kidney; LLT1; lectin-like transcript 1; lPEI; linear polyethylenimine; MALS; multi-angle light scattering; NK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

A high density CHO-S transient transfection system: Comparison of ExpiCHO and Expi293

Keywords: کلیه جنین انسان; CHO cells; HEK293 cells; Transient transfection; Post-translational modification; Glycosylation; BLI; Biolayer Interferometry; CHO; Chinese Hamster Ovary; CV; Column Volume; EBNA; Epstein-Barr Nuclear Antigen-1; HEK293; Human Embryonic Kidney; PTM; Post-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites

Keywords: کلیه جنین انسان; Ataxin-3; Spinocerebellar ataxia type 3; Mass spectrometry; Neurodegeneration; Ubiquitination; Phosphorylation; DUB; deubiquitinating enzyme;; HD; Huntington's disease; HEK; human embryonic kidney;; LC-MS/MS; liquid chromatography tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart

Keywords: کلیه جنین انسان; ChIP; chromatin immunoprecipitation; cRNA; complementary RNA; ddPCR; droplet digital PCR; GATA-BS; GATA binding sites; HEK; human embryonic kidney; Re-ChIP; sequential ChIP; NaV1.5; sodium channel, voltage-gated, type V alpha subunit; TSS; transcription s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together

Keywords: کلیه جنین انسان; CSFM; complete serum-free medium; EGF; epidermal growth factor; HEK; human embryonic kidney; HSG; HEPES-buffered saline with glucose; ILV; intralumenal vesicle; MPR; mannose-6-phosphate receptor; PAM; peptidylglycine α-amidating monooxygenase; PAL; pepti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Optogenetic Control of Ca2 + and Voltage-Dependent Large Conductance (BK) Potassium Channels

Keywords: کلیه جنین انسان; ChR; channelrhodopsin; CatCh; Calcium translocating Channelrhodopsin; BK; Big Potassium; HEK; human embryonic kidney; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; Cav; voltage-gated calcium; optogenetics; BK channel; channelrhodops

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The identification of a novel isoform of EphA4 and ITS expression in SOD1G93A mice

Keywords: کلیه جنین انسان; ALS; amyotrophic lateral sclerosis; BCA; bicinchoninic acid; CHO; Chinese hamster ovary; DAPI; 4′,6-diamidino-2-phenylindole; EphA; ephrin type-A receptor; EphA4-FL; full-length EphA4; EphB; ephrin type-B receptor; ESTs; expressed sequence tag sequences

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1

Keywords: کلیه جنین انسان; DRG; dorsal root ganglion neuron; TRP; transient receptor potential; ER; endoplasmic reticulum; AITC; allyl isothiocyanate; HEK; human embryonic kidney; BCTC; 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide; BABTA; 1,2-Bis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The effects of RAMPs upon cell signalling

Keywords: کلیه جنین انسان; Receptor activity modifying protein; G protein-coupled receptor; Signalling; Trafficking; Coupling; AM; adrenomedullin; AMY; amylin; CaSR; calcium-sensing receptor; CGRP; calcitonin gene-related peptide; CHO; chinese hamster ovary; CLR; calcitonin recepto

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway

Keywords: کلیه جنین انسان; SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Thiol-reactive drug substrates of human P-glycoprotein label the same sites to activate ATPase activity in membranes or dodecyl maltoside detergent micelles

Keywords: کلیه جنین انسان; P-glycoprotein drug-binding sites; ABC protein; n-Dodecyl-β-D-maltoside detergent; Tariquidar; Thiol reactive verapamil and rhodamine; ABC; ATP-binding cassette; DM; n-dodecyl-β-D-maltoside; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; hum

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells

Keywords: کلیه جنین انسان; AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

The yeast Ste2p G protein-coupled receptor dimerizes on the cell plasma membrane

Keywords: کلیه جنین انسان; BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; C-EGFP; C-terminal domain of enhanced green protein; EGFP; enhanced green fluorescent protein; ER; endoplasmic reticulum; FRET; Förster resonance energy tran

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Lysophosphatidylcholine export by human ABCA7

Keywords: کلیه جنین انسان; Aβ; amyloid β; ABC; ATP-binding cassette; AD; Alzheimer's disease; apoA-I; apolipoprotein A-I; apoE; apolipoprotein E; APP; amyloid precursor protein; BHK; baby hamster kidney; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; GFP; gr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

TRAF1 Is Critical for DMBA/Solar UVR-Induced Skin Carcinogenesis

Keywords: کلیه جنین انسان; AK; actinic keratosis; DMBA; 7,12-dimethylbenz[a]anthracene; ERK; extracellular signal-regulated protein kinase; HA; hemagglutinin; HEKa; adult human epidermal keratinocyte; HEK; human embryonic kidney; K; keratin; MAPK; mitogen-activated protein kinase;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

The antidepressant bupropion is a negative allosteric modulator of serotonin type 3A receptors

Keywords: کلیه جنین انسان; Antidepressant; Bupropion; Hydroxybupropion; 5-HT3A receptors; Pentameric ligand-gated ion channels; 5-HT3AR; 5-hydroxytryptamine type 3A receptor; 5-HT; 5-hydroxytryptamine; ACh; acetylcholine; α-BgTx; α-bungarotoxin; CNS; central nervous system; DA; d

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells

Keywords: کلیه جنین انسان; EP selectivity; G protein-coupled receptor (GPCR); Prostaglandin; Prostaglandin E1; Prostaglandin E2; Receptor regulation; AA; arachidonic acid; COX-1 and -2; cyclooxygenase-1 and -2, respectively; cPGES; cytosolic PGES; DGLA; dihomo-γ-linolenic acid; EP

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه

Measuring inhibition of monoamine reuptake transporters by new psychoactive substances (NPS) in real-time using a high-throughput, fluorescence-based assay

Keywords: کلیه جنین انسان; Dopamine transporter; Norepinephrine transporter; Serotonin transporter; Fluorescent monoamine substrate; Designer drugs; Drug screening; 2C-B; 2,5-dimethoxy-4-bromophenethylamine; 4-FA; 4-fluoroamphetamine; 5-APB; 5-(2-aminopropyl)benzofuran; 25B-NBOMe;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2017 سفارش ترجمه

Direct coupling of the HER4 intracellular domain (4ICD) and STAT5A signaling is required to induce mammary epithelial cell differentiation

Keywords: کلیه جنین انسان; 4ICD; HER4 intracellular domain; ATCC; American type culture collection; EGF; epidermal growth factor; EGFP; enhanced green fluorescent protein; EGFR; epidermal growth factor family; ERα; estrogen receptor alpha; FBS; fetal bovine serum; HEK; human embry

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

CRASP: CFP reconstitution across synaptic partners

Keywords: کلیه جنین انسان; CRASP; GRASP; CFP reconstitution; GFP reconstitution; Connectome; Drosophila; GRASP; GFP reconstitution across synaptic partners; CRASP; CFP reconstitution across synaptic partners; HEK; human embryonic kidney; PN; projection neuron; KC; Kenyon cells; IHC

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

P-glycoprotein ATPase activity requires lipids to activate a switch at the first transmission interface

Keywords: کلیه جنین انسان; P-glycoprotein; ABC protein; Disulfide cross-linking; Switch; Transmission interface; ATPase activity; ABC; ATP-binding cassette; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; human embryonic kidney; TM; transmembrane; TMD; transmembrane doma

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

CED-4 is an mRNA-binding protein that delivers ced-3 mRNA to ribosomes

Keywords: کلیه جنین انسان; Apoptosis; RNA binding protein; L10a; Translation; Translocation; ced; cell death abnormal; egl; egg-laying defective; HEK; human embryonic kidney; GFP; green fluorescent protein; MG132; Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, Z-LLL-CHO;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

CASZ1 loss-of-function mutation associated with congenital heart disease

Keywords: کلیه جنین انسان; CHD; congenital heart disease; VSD; ventricular septal defect; PCR; polymerase chain reaction; TH-luc; tyrosine hydroxylase- luciferase; HEK; human embryonic kidney; Congenital heart disease; Genetics; Transcription factor; CASZ1; Reporter gene assay;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7

Keywords: کلیه جنین انسان; ACKR; atypical chemokine receptor; CCKAR; cholecystokinin A receptor; CCL; chemokine (CC motif) ligand; CHO; Chinese hamster ovary; CXCL; chemokine (CXC motif) ligand; CX3CL; chemokine (CX3C motif) ligand; EBV; Epstein-Barr virus; ERK; extracellular rec

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Oxidation differentially modulates the recombinant voltage-gated Na+ channel α-subunits Nav1.7 and Nav1.8

Keywords: کلیه جنین انسان; TTX; tetrodotoxin; Nav; voltage-gated sodium channel; TRP; transient receptor potential; HEK; human embryonic kidney; EGFP; green fluorescent protein; DRG; dorsal root ganglion; Nociception; Pain; Oxidative stress; Sodium channel; Nav1.7; Nav1.8;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1

Keywords: کلیه جنین انسان; Arachidonic acid; Cyclooxygenase-2; Microsomal prostaglandin E2 synthase; Polyunsaturated fatty acid; Prostaglandin E2; 10aa; 10 amino acid residues; AA; arachidonic acid; CHD; coronary heart disease; COX-1 and -2, respectively; cyclooxygenase-1 and -2; c

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

TRIM32 ubiquitin E3 ligase, one enzyme for several pathologies: From muscular dystrophy to tumours

Keywords: کلیه جنین انسان; TRIM; tripartite motif; RING; really interesting new gene; NHL, NCL-1; HT2A and lin-41; LGMD; limb-girdle muscular dystrophy; XIAP; X-linked inhibitor of apoptosis; PIAS; protein inhibitor of activated STAT; NDRG2; N-myc downstream regulated gene 2; Abi2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

A-type lamin-dependent homo-oligomerization for pY19-Caveolin-2 to function as an insulin-response epigenetic regulator

Keywords: کلیه جنین انسان; ER; endoplasmic reticulum; PM; plasma membrane; Cav-2; Caveolin-2; INM; inner nuclear membrane; STAT3; signal transducer and activator of transcription 3; PTP1B; protein tyrosine phosphatase 1B; H3K9me3; histone H3 lysine 9 trimethylation; H3K9ac; histone

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The impact of lemon pectin characteristics on TLR activation and T84 intestinal epithelial cell barrier function

Keywords: کلیه جنین انسان; DDM; digested pectin with degree of methyl esterification; DM; degree of methyl esterification; DP; degree of polymerization; ECIS; electric cell substrate impedance sensing; GalA; galacturonic acid; GM-CSF; granulocyte macrophage-colony stimulating facto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Collectin CL-P1 utilizes C-reactive protein for complement activation

Keywords: کلیه جنین انسان; CRP; C-reactive protein; PTX3; pentraxin 3; CRD; carbohydrate recognition domain; Col; collagen; TCC; terminal complement complex; SR; scavenger receptor; CL-P1; collectin placenta 1; SR-AI; scavenger receptor type I; LOX-1; lectin-like oxidized LDL recep

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Isolation and characterization of the corticotropin-releasing factor-related diuretic hormone receptor in Rhodnius prolixus

Keywords: کلیه جنین انسان; AMG; anterior midgut; BAPTA-AM; 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; BSA; bovine serum albumin; CT; calcitonin; CAP2b; cardioacceleratory peptide 2b; CNS; central nervous system; CHO; Chinese hamster ovary; CRF; corticotropin-rele

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular mechanisms of LL-37-induced receptor activation: An overview

Keywords: کلیه جنین انسان; AMP; antimicrobial peptide; APD; antimicrobial peptide database; IFN; interferon; DC; dendritic cell; NK-cells; natural killer cells; GPCR; G protein-coupled receptor; RTK; receptor tyrosine kinase; LGIC; ligand-gated ion channel; TLR; toll-like receptor;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

KCNE4 and KCNE5: K+ channel regulation and cardiac arrhythmogenesis

Keywords: کلیه جنین انسان; AMME; Alport syndrome, intellectual disability, midface hypoplasia and elliptocytosis; CHO; Chinese Hamster ovary; HEK; human embryonic kidney; IKs/IsK; slowly activating K+ current; KChIP; K+ channel interacting protein; Kv channel; voltage-gated potassi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Interactions between amiodarone and the hERG potassium channel pore determined with mutagenesis and in silico docking

Keywords: کلیه جنین انسان; AF; atrial fibrillation; diLQTS; drug induced long QT syndrome; DEA; desethylamiodarone; HEK; human embryonic kidney; hERG; human-Ether-à-go-go-Related Gene; IC50; half-maximal inhibitory concentration; IhERG; ionic current carried by hERG potassium chan

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Function of brain α2B-adrenergic receptor characterized with subtype-selective α2B antagonist and KO mice

Keywords: کلیه جنین انسان; ADHD; attention deficit hyperactivity disorder; CNS; central nervous system; HEK; human embryonic kidney; KO; knockout; PPI; pre-pulse inhibition; WT; wildtype; adrenergic; α2B-receptor; sensorimotor; stereotypy; compulsivity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers

Keywords: کلیه جنین انسان; antiarrhythmic drugs; atrial fibrillation; drug targets; electrophysiology; personalized medicine; rhythm control; AAD; antiarrhythmic drug; APD; action potential duration; ERP; effective refractory period; HEK; human embryonic kidney; LA; left atrium; LA

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Novel multifunctional dopamine D2/D3 receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties

Keywords: کلیه جنین انسان; TPP; triphenylphosphine; NaHMDS; sodium bis(trimethylsilyl)amide; DIBALH; diisobutylaluminium hydride; TBS; tert-butyldimethylsilyl; TBDMSCl; tert-butyl(chloro)dimethylsilane; PCC; pyridinium chlorochromate; TBAF; tetra-n-butylammonium fluoride; HMDS; hex

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Knockdown of long non-coding RNA MALAT1 increases the blood-tumor barrier permeability by up-regulating miR-140

Keywords: کلیه جنین انسان; GBM; glioblastoma multiforme; BTB; blood-tumor barrier; BBB; blood-brain barrier; CNS; central nervous system; ZO; zonula occludens; ncRNAs; non-coding RNAs; lncRNAs; long non-coding RNAs; MALAT1; metastasis associated lung adenocarcinoma transcript 1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Pluripotency induction in HEK293T cells by concurrent expression of STELLA, OCT4 and NANOS2

Keywords: کلیه جنین انسان; NANOS2; OCT4; Reprogramming; Starvation; STELLA; Stra8; AP; alkaline phosphatase; GSC; Germline stem cell; HEK; Human embryonic kidney; SON; STELLA plus OCT4 plus NANOS2;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2016 سفارش ترجمه