دانلود مقالات ISI درباره کلیه جنین انسان + ترجمه فارسی

Beyond knockout: A novel homodimerization-targeting MyD88 inhibitor prevents and cures type 1 diabetes in NOD mice

Keywords: کلیه جنین انسان; Type 1 diabetes; Therapeutics; MyD88; MyD88 inhibitor; DC; MyD88; myeloid differentiation factor 88; T1D; type 1 diabetes; NOD mice; non-obese diabetic mice; DC; dendritic cell; TLR; Toll-like receptor; TIR; Toll-interleukin receptor; CMC; carboxyl methyl

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling

Keywords: کلیه جنین انسان; APC; Adenomatous Polyposis Coli protein; CKI; casein kinase-1; DISC1; Disrupted in Schizophrenia 1; DLG1; discs large 1; GSK3β; glycogen synthase kinase 3 beta; HEK; human embryonic kidney; LEF; lymphocyte enhancer-binding factor; PSD; postsynaptic densi

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2016 سفارش ترجمه

A novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias

Keywords: کلیه جنین انسان; NaV1.5; sodium channels; VCF; voltage clamp fluorometry; F-V; voltage sensor movement; VSD; voltage sensing domain; ECG; electrocardiogram; CPR; cardiopulmonary resuscitation; AED; automated external defibrillators; HEK; human embryonic kidney; EGFP; enha

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Muscarinic Receptor Induced Contractions of the Detrusor are Mediated by Activation of TRPC4 Channels

Keywords: کلیه جنین انسان; urinary bladder; muscle contraction; transient receptor potential channels; acetylcholine; cholinergic agents; 2-APB; 2-aminoethoxydiphenyl borate; 4-DAMP; 1,1-dimethyl-4-diphenylacetoxypiperidinium; ACh; acetylcholine; ATP; adenosine triphosphate; BK; la

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling

Keywords: کلیه جنین انسان; BMDMs; bone marrow-derived macrophages; c-di-GMP; cyclic diguanylate monophosphate; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; GST; Glutathione S-transferase; HEK293T; human embryonic kidney; IB; immunobl

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

Polygenic case of long QT syndrome confirmed through functional characterization informs the interpretation of genetic screening results

Keywords: کلیه جنین انسان; APD; action potential duration; APD90; action potential duration at 90% repolarization; ECG; electrocardiogram; HEK; human embryonic kidney; LQT; long QT; LQTS; long QT syndrome; LQT(2-3); long QT syndrome type (2-3); VUS; variant of unknown significance;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting the Fas/FasL system in Rheumatoid Arthritis therapy: Promising or risky?

Keywords: کلیه جنین انسان; AP; activator protein; APAF; apoptosis protease activating factor; CAD; caspase-activated DNase; CHO; Chinese hamster ovary; CIA; collagen-induced arthritis; DD; death domain; DED; death effector domain; DISC; death-inducing signaling complex; DR; death r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors

Keywords: کلیه جنین انسان; CA; Candida albicans extract; HEK; human embryonic kidney; IL; interleukin; mAb; monoclonal antibody; PBMC; peripheral blood mononuclear cell; PBS; phosphate buffered saline; PHA; phytohemagglutinin; rh; recombinant human; RT; room temperature; Th; T-help

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Dissecting the role of the foxp3 gene in the joint genetic susceptibility to autoimmune thyroiditis and diabetes: A genetic and functional analysis

Keywords: کلیه جنین انسان; APS3v; autoimmune polyglandular syndrome type 3; AIRE; autoimmune regulator; AITD; autoimmune thyroiditis; bp; base pair(s); CTLA-4; cytotoxic T-lymphocyte antigen; Δ; deletion; dNTP; deoxyribonucleoside triphosphate; FOXP3; Forkhead Box Protein 3; GAPDH

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Manufacturing process used to produce long-acting recombinant factor VIII Fc fusion protein

Keywords: کلیه جنین انسان; rFVIIIFc; Human cell line; HEK 293H; Hemophilia A; Manufacturing; Recombinant; aPTT; activated partial thromboplastin time; α-Gal; galactose-α-1,3-galactose; BDD; B domain-deleted; FcRn; neonatal Fc receptor; FVIII; factor VIII; HC; heavy chain; HCP; ho

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor

Keywords: کلیه جنین انسان; Neuropeptide Y; G protein-coupled receptor; Extracellular-regulated protein kinase; Human embryonic kidney; IGFR; β-arrestin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Etomidate uniquely modulates the desensitization of recombinant α1β3δ GABAA receptors

Keywords: کلیه جنین انسان; EGTA; ethylene glycol tetraacetic acid; HEK; human embryonic kidney; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; THDOC; tetrahydrodeoxycorticosterone; GABAA receptors; δ subunit; concatemers; etomidate; desensitization; deactivation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Positive modulation of synaptic and extrasynaptic GABAA receptors by an antagonist of the high affinity benzodiazepine binding site

Keywords: کلیه جنین انسان; GABAA receptors; Chloride channels; Electrophysiology; Xenopus oocyte; Benzodiazepine; Positive allosteric modulator; GABAA receptor; gamma-aminobutyric acid type A receptor; DMSO; dimethylsulfoxide; HEK; human embryonic kidney; SJM-3 (PubChem CID: 497135

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Subcellular localization and internalization of the vasopressin V1B receptor

Keywords: کلیه جنین انسان; AVP; arginine-vasopressin; C-terminus; carboxyl-terminus; CHO; Chinese hamster ovary; DAB; 3,3′-diaminobenzidine; DMEM; Dulbecco's modified Eagle's medium; GFP; green fluorescent protein; GPCRs; G-protein coupled receptors; HEK; human embryonic kidn

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

Keywords: کلیه جنین انسان; BSA; bovine serum albumin; CRD; cysteine-rich domain; dFBS; dialyzed fetal bovine serum; DPBS; Dulbecco's Phosphate-Buffered Saline; DTT; dithiothreitol; ECD; extracellular domain; ELISA; Enzyme-Linked Immunosorbent Assay; ER; endoplasmic reticulum; EtO

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The role of TRPA1 in muscle pain and mechanical hypersensitivity under inflammatory conditions in rats

Keywords: کلیه جنین انسان; AUC; area under the curve; AUs; action units; CFA; complete Freund's adjuvant; CYP; cyclophosphamide; DRG; dorsal root ganglia; HEK; human embryonic kidney; NMDA; N-Methyl-d-aspartate; PBS; phosphate-buffered saline; RGS; rat grimace scale; ROS; reactiv

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The Susd2 protein regulates neurite growth and excitatory synaptic density in hippocampal cultures

Keywords: کلیه جنین انسان; aa; amino acid(s); AMOP; adhesion-associated domain in Muc-4 and other proteins; CCP; complement control protein; DIV; days in vitro; HA; human influenza hemagglutinin; HEK; human embryonic kidney; HRP; horseradish peroxidase; LRR; leucine rich repeat; SC

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Site-specific structural characterization of O-glycosylation and identification of phosphorylation sites of recombinant osteopontin

Keywords: کلیه جنین انسان; OPN; osteopontin; PTM; post-translational modification; O-GlcNAc; O-linked β-N-acetylglucosamine; MALDI-TOF; matrix-assisted laser desorption ionization-time of flight; MS; mass spectrometry; PMF; peptide mass fingerprint; MS/MS; tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Constitutive expression of tdTomato protein as a cytotoxicity and proliferation marker for space radiation biology

Keywords: کلیه جنین انسان; Mammalian cells; Radiation response; Fluorescent protein; Cytotoxicity; Proliferation; tdTomato; A260; absorbance at 260 nm; A280; absorbance at 280 nm; BP; bandpass; CellRad; Cellular Responses to Radiation in Space; CMV; Cytomegalovirus; Cu; copper; DMS

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

RGS2 and RGS4 proteins: New modulators of the κ-opioid receptor signaling

Keywords: کلیه جنین انسان; 293 F; cell line of human embryonic kidney origin; 6× His; hexahistidine; aa; amino acids; AC; adenylyl cyclase; AR; adrenergic receptors; AT1; Angiotensin Receptor 1; CT; carboxyl terminus; ΔΝRGS4; RGS4 lacking its N-terminal domain; DAMGO; [d-Ala2,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Early growth response-1 facilitates enterovirus 71 replication by direct binding to the viral genome RNA

Keywords: کلیه جنین انسان; 3′UTR; 3′-untranslated region; 5′UTR; 5′-untranslated region; CNS; central nervous system; Co-IP; co-immunoprecipitation; CPE; cytopathogenic effect; DMEM; Dulbecco's modified Eagle's medium; EGR1; early growth response-1; eIF4E; eukaryotic initia

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cellulose alters the expression of nuclear factor kappa B-related genes and Toll-like receptor-related genes in human peripheral blood mononuclear cells

Keywords: کلیه جنین انسان; ATM; ataxia telangiectasia mutated; AUC; area under the curve; CD; cluster of differentiation; ECIS; electric cell substrate impedance sensing; EU; endotoxin units; FBS; foetal bovine serum; HEK; human embryonic kidney; IL-1Ra; interleukin 1 receptor anta

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Keywords: کلیه جنین انسان; Crk; CT10 regulator of kinase; CRKL; Crk-like protein; ERK; extracellular signal regulated kinase; FCS; foetal calf serum; Gab1; Grb2-associated binder 1; Grb2; growth factor receptor bound protein 2; IL-6; interleukin-6; JAK; Janus kinase; HEK; human emb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Downregulation of kinin B1 receptor function by B2 receptor heterodimerization and signaling

Keywords: کلیه جنین انسان; kB1R; kinin B1 receptor; kB2R; bradykinin B2 receptor; GPCR; G protein-coupled receptor; BK; bradykinin; KD; kallidin; DABK; des-Arg9-bradykinin; DAKD; des-Arg10-kallidin; LV; left ventricular; ACE; angiotensin I converting enzyme; DMEM; Dulbecco's Modifi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting

Keywords: کلیه جنین انسان; Ubiquitin; Ubiquitin-binding-domain; Immunoblotting; Deubiquitylase; Ubiquitin chain topology; DMP; dimethyl pimelidinate; DUB; deubiquitylase; GST; glutathione S-transferase; HEK; human embryonic kidney; IAA; iodoacetamide; IL-1R; IL-1 receptor; IMAC; im

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels

Keywords: کلیه جنین انسان; ADT-OH; anethole dithiolethione, 5-[p-methoxyphenyl]3H-1,2-dithiole-3-thione; AP219; 9-(Carboxynonyl)triphenylphosphonium bromide; AP39; (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide; ApoE; apolioprotein E; ARRIVE;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

The Nuclear Factor κB pathway: A link to the immune system in the radiation response

Keywords: کلیه جنین انسان; Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Space experiment “Cellular Responses to Radiation in Space (CellRad)”: Hardware and biological system tests

Keywords: کلیه جنین انسان; ATM; Ataxia telangiectasia mutated; CellRad; Cellular Responses to Radiation in Space; CMV; cytomegalovirus; d2EGFP; destabilized variant of EGFP; DDR; DNA damage response; DSB; double strand breaks; DLR; German Aerospace Center; DMSO; dimethyl sulfoxide;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

A subset of N-substituted phenothiazines inhibits NADPH oxidases

Keywords: کلیه جنین انسان; CHO; Chinese hamster ovary; DMSO; dimethyl sulfoxide; DUOX; dual oxidase; DMEM; Dulbecco׳s modified Eagle medium; DPI; diphenyleneiodonium; ESP; electrostatic potential; FBS; fetal bovine serum; GFP; green fluorescent protein; HBSS; Hanks׳ buffered salt

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of 3-phenethylazetidine derivatives as triple reuptake inhibitors

Keywords: کلیه جنین انسان; 5-HT; serotonin; NE; norepinephrine; DA; dopamine; SSRI; selective serotonin reuptake inhibitor; SNRI; serotonin norepinephrine reuptake inhibitor; TRI; triple reuptake inhibitor; CYP; cytochrome P450; hERG; human ether-a go-go-related gene; HEK; human em

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

A salt bridge between Arg-20 on parathyroid hormone (PTH) and Asp-137 on the PTH1 receptor is essential for full affinity

Keywords: کلیه جنین انسان; PTH; parathyroid hormone; PTHrP; parathyroid hormone-related peptide; 125I-rPTH(1-34); 125I-[Nle8,21,Tyr34]rPTH(1-34)NH2; MBS; membrane binding solution; GPCR; G protein-coupled receptor; N domain; N-terminal extracellular domain; PTH1; PTH/PTHrP rece

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells

Keywords: کلیه جنین انسان; Aβ; amyloid beta peptide; AD; Alzheimer's disease; ADAM; A disintegrin and metalloproteinase; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE1; beta-secretase; CHO; Chinese hamster ovary; CTF; C-terminal fragment; DN; dominant negative; FA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7

Keywords: کلیه جنین انسان; TLR; toll-like receptor; TIR; toll-interlerkin 1 receptor; LRR; leucine-rich repeats; NF-κB; nuclear factor-κB; IRF7; interferon regulatory factor 7; MyD88; myeloid differentiation factor 88; HEK; human embryonic kidney; FCS; fetal calf serum; PBS; phos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Mislocalization of K+ channels causes the renal salt wasting in EAST/SeSAME syndrome

Keywords: کلیه جنین انسان; Epithelial sodium transport; EAST/SeSAME syndrome; Intracellular trafficking; Kidney; Potassium channel; Tubulopathy; Kir; inwardly rectifying K+ channel; DCT; distal convoluted tubule; GFP; green fluorescent protein; HEK; human embryonic kidney; NCC; Na+

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: کلیه جنین انسان; AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences

Keywords: کلیه جنین انسان; CID; collision-induced dissociation; DTT; dithiothreitol; ECD; electron capture dissociation; Glc; glucose; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HEK; Human Embryonic Kidney; LC; liquid chromatography; MS; mass spectrometry; PAS; peri

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting kidney CLC-K channels: Pharmacological profile in a human cell line versus Xenopus oocytes

Keywords: کلیه جنین انسان; NFA; niflumic acid; HEK; human embryonic kidney; MDCK; Madin Darby Canine Kidney; ATP; adenosine 5′-triphosphate; DCT; distal convoluted tubule; CLC-K chloride channel; Kidney; Pharmacology; HEK293 cell; Bartter syndrome; Hypertension;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives

Keywords: کلیه جنین انسان; Novel psychoactive substance; Monoamine; Transporter; Receptor; 2-AI; 2-aminoindane; BZP; 1-benzylpiperazine; DA; dopamine; DAT; dopamine transporter; D2PM; diphenyl-2-pyrrolidinemethanol; 2-DPMP; desoxypipradrol or 2-diphenylmethylpiperidine; HEK; human

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Keywords: کلیه جنین انسان; Akt1; v-akt murine thymoma viral oncogene homolog 1; AMBRA; Autophagy/Beclin-1 regulator 1; AMPK; AMP-dependent protein kinase; ATG; autophagy-related; BECN1; beclin 1; DEPTOR; DEP domain containing mTOR-interacting protein; EGFR; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

TRAF-mediated modulation of NF-kB AND JNK Activation by TNFR2

Keywords: کلیه جنین انسان; AIP1; ASK1 interacting protein; AP-1; activating protein 1; BKO; binding knock out; CRMA; cytokine response modifier A; cIAP; cellular inhibitor of apoptosis; DMEM; Dulbecco modified Eagle's medium; FLAG; FLAG peptide; HA; hemagglutinin; HEK; human embryo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Biophysical characterization of sites of host adaptive mutation in the influenza A virus RNA polymerase PB2 RNA-binding domain

Keywords: کلیه جنین انسان; ATCC; American Type Culture Collection; EMSA; electrophoretic mobility shift assays; FAM; fluorescein amidite; FLuc; firefly luciferase; HEK; human embryonic kidney; NMR; nuclear magnetic resonance; RdRp; RNA-dependent RNA polymerase; RLuc; Renilla lucife

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions

Keywords: کلیه جنین انسان; CA; capsid; HEK; human embryonic kidney; HTLV; human T-cell leukemia virus; IF; immunofluorescence; IP; immunoprecipitation; LMB; leptomycin B; MOI; multiplicity of infection; NB; nuclear body; PBS; phosphate buffer saline; PML; promyelocytic leukemia; SU

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Functional interaction of the cystic fibrosis transmembrane conductance regulator with members of the SLC26 family of anion transporters (SLC26A8 and SLC26A9): Physiological and pathophysiological relevance

Keywords: کلیه جنین انسان; cAMP; cyclic adenosine monophosphate; CF; cystic fibrosis; CFBE4Io-; cystic fibrosis bronchial epithelial cell line; CFTR; cystic fibrosis transmembrane conductance regulator; CHO-K1; Chinese hamster ovary-K1; DHPLC; denaturing high performance liquid chr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Aspp2 negatively regulates body growth but not developmental timing by modulating IRS signaling in zebrafish embryos

Keywords: کلیه جنین انسان; aa; amino acids; Akt/PKB; protein kinase B; Ank; ankyrin repeats; AO; Acridine orange; BrdU; 5-bromo-2′-deoxyuridine; EGFP; enhanced GFP; Erk; extracellular signal-regulated kinases; HEK; human embryonic kidney; hpf; hour post fertilization; IGF-IR; IGF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor

Keywords: کلیه جنین انسان; GPCR; Adenosine receptor; Purines; Cyclic AMP; Calcium; Arrestin; BAY60-6583 (BAY, LUF6210); 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]acetamide; cyclic AMP (cAMP); 3′5′-cyclic adenosine monophosphate; CGS21680; 2-[p-(2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Functional assessment of the mutational effects of human IRAK4 and MyD88 genes

Keywords: کلیه جنین انسان; DD; death domain; HEK; human embryonic kidney; ID; internal domain; IRAK; Interleukin-1 receptor-associated kinase; MyD88; myeloid differentiating factor 88; Mal; MyD88 adaptor-like; NMR; nuclear magnetic resonance; ELISA; enzyme-linked immunosorbent assa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptors

Keywords: کلیه جنین انسان; Antagonist; Cys-loop; Ion channel; Radioligand; 5-HT3; Agonist; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HTBP; an AChBP mutant modified to

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation

Keywords: کلیه جنین انسان; BCA; bicinchoninic acid; DMEM; dulbecco's modified eagles medium; GCK; glucokinase gene; Glc; α-D-glucose; GKRP; glucokinase regulatory protein; HEK; human embryonic kidney; hGK; human glucokinase; IFG; impaired fasting glucose; MIN; mouse insulinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux

Keywords: کلیه جنین انسان; ABC; ATP-binding cassette transporter; AcLDL; acetylated LDL; apo; apolipoprotein; BSA; bovine serum albumin; CAV1; caveolin-1; CL; cytoplasmic loop; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

A subset of chicken statoacoustic ganglion neurites are repelled by Slit1 and Slit2

Keywords: کلیه جنین انسان; CMV; cytomegalovirus; CNTF; Ciliary Neurotrophic Factor; df; degrees of freedom; E; embryonic day; EF-1α; elongation factor 1 alpha; GFP; green fluorescent protein; HBSS; Hank's Balanced Salt Solution; HEK; human embryonic kidney; HH; Hamburger and Hamil

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه