دانلود مقالات ISI درباره چگونه + ترجمه فارسی

تحویل داروی ترکیبی شیمیایی بیولوژیک با استفاده از نانوذرات دندریمر هدف گیرنده فولات برای درمان سرطان ریه

Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment

Keywords: چگونه; Den; polyamidoamine dendrimer; CDDP; Cis-diamminodichloridoplatinum (II); FA; folic acid; FRA; folate receptor-α; HuR; human antigen R; siRNA; small interfering RNA; PEI; polyethyleneimine; OPDA; O-phenylenediamine; Lung cancer; Dendrimer; FRA; CDDP; HuR

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

کمک بخشی پورینیریک به اسکلروز جانبی آمیوتروفی

Purinergic contribution to amyotrophic lateral sclerosis

Keywords: چگونه; CD39; M1/M2 microglia; Motoneuron; Oligodendrocyte; P2X7; P2Y12; ALS; amyotrophic lateral sclerosis; BBG; Brilliant Blue G; BDNF; brain-derived neurotrophic factor; BzATP; 2′-3′-O-(benzoyl-benzoyl) ATP; fALS; familial ALS; FUS; fused in sarcoma; HuR

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

سیستم های تخریب در نارسایی قلبی

Degradation systems in heart failure

Keywords: چگونه; AMPK; AMP-activated protein kinase; ASK1; apoptosis signal-regulating kinase 1; Atg; autophagy-related; ARE; AU-rich element; AUF; ARE RNA binding protein; BRF; butyrate response factor; CaMK; Ca2 +/calmodulin-dependent protein kinase; CUGBP; CUG-binding

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

High cytoplasmic HuR expression is associated with advanced pT stage, high grade and increased microvessel density in urothelial bladder carcinoma

Keywords: چگونه; Bladder cancer; HuR; Stage; Grade; Microvessel density;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Knockdown of HuR represses osteosarcoma cells migration, invasion and stemness through inhibition of YAP activation and increases susceptibility to chemotherapeutic agents

Keywords: چگونه; HuR; YAP; Osteosarcoma; Adriamycin; Epithelial-mesenchymal transition;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity

Keywords: چگونه; HuR; YAP; Cervix carcinoma; Stemness; Adriamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Adenosine causes read-through into the late region of the HPV16 genome in a guanosine-dependent manner

Keywords: چگونه; Papillomavirus; HPV16; Nucleoside; Purine; Adenosine; Polyadenylation; Splicing; HuR; ENT1;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Interaction of miR-125b-5p with Human antigen R mRNA: Mechanism of controlling HCV replication

Keywords: چگونه; HCV; HuR; miR-125b-5p; Viral replication; Translation;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR)

Keywords: چگونه; Cell migration; Metastasis; microRNA; Colon cancer; HuR;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

Regulation of the ARE-binding proteins, TTP (tristetraprolin) and HuR (human antigen R), in inflammatory response in astrocytes

Keywords: چگونه; TTP (tristetraprolin); HuR (human antigen R); Cyclooxygenase 2; Toll-like receptor (TLR) agonists; Cycloheximide; mRNA degradation; Inflammation; Astrocytes; p38 MAPK; ARE; Adenine-uridine rich elements; DMEM; Dulbecco's modified Eagle's medium; FGL; flag

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocytic expression of the RNA regulator HuR accentuates spinal cord injury in the acute phase

Keywords: چگونه; BMS; Basso Mouse Scale; GFAP; glial fibrillary acidic protein; RBP; RNA binding protein; SCI; spinal cord injury; Tg; transgenic; WT; wild type littermate controls; HuR; Spinal cord injury (SCI); Post-transcriptional regulation; Blood spinal cord barrier;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

HuR promotes breast cancer cell proliferation and survival via binding to CDK3 mRNA

Keywords: چگونه; HuR; CDK3; Breast cancer; mRNA stability;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis

Keywords: چگونه; Arsenic; microRNA; Cyclin D1; HuR; Adipogenesis; Mesenchymal stem cell;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Phosphorylation of Tudor-SN, a novel substrate of JNK, is involved in the efficient recruitment of Tudor-SN into stress granules

Keywords: چگونه; SG; stress granule; Tudor-SN; Tudor staphylococcal nuclease; JNK; c-Jun N-terminal kinase; PKR; protein kinase R; PERK; PKR-like endoplasmic reticulum kinase; GCN2; general control nonderepressible 2; HRI; heme-regulated inhibitor kinase; eIF2α; eukaryot

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis

Keywords: چگونه; Multiple sclerosis; Central nervous system; Neuropathic pain; HuR; Relapsing-remitting experimental autoimmune encephalomyelitis; aODN; antisense oligonucleotide; dODN; degenerate oligonucleotide; ELAV protein; embryonic lethal abnormal vision protein; GF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleSilencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2

Keywords: چگونه; Apoptosis; Caspase-2; Colorectal carcinoma cells; HuR; Radiotherapy resistance; CRC; colorectal cancer; DDR; DNA-damage response; HuR; human antigen R; PARP; poly ADP-ribose polymerase; 5′UTR; 5′-untranslated region;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Oleic Acid Induces MiR-7 Processing through Remodeling of Pri-MiR-7/Protein Complex

Keywords: چگونه; miR; microRNA; RNA-BP; RNA-binding protein; pri-miR; primary miR; pre-miR; precursor miR; GBM; glioblastoma multiforme; HuR; Hu antigen R; MSI2; Musashi homolog2; CTL; conserved terminal loop; OA; oleic acid; RRM; RNA recognition motif; EMSA; electrophore

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element RNA-binding protein 1 (AUF1) and poly A binding protein (PABP)

Keywords: چگونه; PCBP1; poly(rC) binding protein 1; MOR; mu opioid receptor; AUF1; AU-rich element RNA-binding protein 1; PABP; poly (A)-binding protein; 3′-UTR; 3′-untranslated region; PKA; protein kinase A; PKC; protein kinase C; CRE; C-rich element; RNA-EMSA; RNA e

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Adrenaline promotes epithelial-to-mesenchymal transition via HuR-TGFβ regulatory axis in pancreatic cancer cells and the implication in cancer prognosis

Keywords: چگونه; Adrenaline; Pancreatic cancer; Migration; HuR; TGFβ; EMT;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

Keywords: چگونه; HCC; Cancer Stem Cells; HuR; Hepatocarcinogenesis; ACTA2; α-smooth muscle actin; Ad; adenovirus; aHSC; activated hepatic stellate cell; AKT; AKT serine/threonine kinase 1; ARE; AU-rich element; BDL; bile duct ligation; BSC; BDL-derived aHSC cell line; CC

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2017 سفارش ترجمه

Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy

Keywords: چگونه; HuR; Heart; Hypertrophy; RNA binding protein; p38 MAPK;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

HUR mRNA expression in ovarian high-grade serous carcinoma effusions is associated with poor survival

Keywords: چگونه; High-grade serous carcinoma; Effusion; HuR; Survival; Immunohistochemistry; Reverse-transcription polymerase chain reaction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Human antigen R is positively associated with malignant aggressiveness via upregulation of cell proliferation, migration, and vascular endothelial growth factors and cyclooxygenase-2 in prostate cancer

Keywords: چگونه; BCR; biochemical recurrence; COX; cyclooxygenase; CRPC; castration-resistant prostate cancer; HO; heme oxygenase; HuR; human antigen-R; IRS; immunoreactive score; KD; knockdown; PCa; prostate cancer; PSA; prostate-specific antigen; RP; radical prostatecto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

HuR represses Wnt/β-catenin-mediated transcriptional activity by promoting cytoplasmic localization of β-catenin

Keywords: چگونه; Wnt/β-catenin; HuR; Transcriptional activity; Cytoplasmic β-catenin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R

Keywords: چگونه; Liver cancer; HuR; NEDDylation; RNA-binding proteins; Post-transcriptional modifications; MLN4924;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma

Keywords: چگونه; Ki-67; MCM6; HuR; miR16; miR519; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis

Keywords: چگونه; A2AR; A2A adenosine receptor; AD; Alzheimer's disease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; AREs; adenylate- and uridylate-rich elements; ELAV; embryonic lethal abn

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Dimerization model of the C-terminal RNA Recognition Motif of HuR

Keywords: چگونه; AREs; Adenylate and uridylate Rich Elements; BD; Brownian Dynamics; COM; center of mass; ELAV; Embryonic Lethal and Abnormal Vision; Grb7; Growth factor receptor-bound protein 7; HuR; Human antigen R; mRNA; messenger RNA; MD; Molecular Dynamics; NMR; nucl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-7: A miRNA with expanding roles in development and disease

Keywords: چگونه; ACK1; activated CDC42 kinase 1; BASP1; brain abundant, membrane attached signal protein 1; c-Myc; v-Myc avian myelocytomatosis viral oncogene homolog; CD57; cluster of differentiation 57; CD44; cluster of differentiation 44; ciRS-7; circular RNA sponge fo

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The cytoskeletal inhibitors latrunculin A and blebbistatin exert antitumorigenic properties in human hepatocellular carcinoma cells by interfering with intracellular HuR trafficking

Keywords: چگونه; ARE; AU-rich element; COX-2; cyclooxygenase-2; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; HuR; human antigen R; RNP; ribonucleoprotein; shRNA; small hairpin RNA; siRNA; small interfering RNA; 3′UTR; 3′ untranslated region; Cytoskeletal

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

microRNA-7: A tumor suppressor miRNA with therapeutic potential

Keywords: چگونه; ACK1; activated CDC42 kinase 1; Akt; V-Akt murine thymoma viral oncogene homolog; BCL-2; B-cell CLL/lymphoma 2; CCNE1; cyclin E1; ciRS-7; circular RNA sponge 7; c-Myc; V-Myc avian myelocytomatosis viral oncogene homolog; EGFR; epidermal growth factor rece

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

A novel cantharidin analog N-Benzylcantharidinamide reduces the expression of MMP-9 and invasive potentials of Hep3B via inhibiting cytosolic translocation of HuR

Keywords: چگونه; N-Benzylcantharidinamide; Cancer; Invasion; MMP-9; HuR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleAMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression

Keywords: چگونه; AMPK; AMP-activated protein kinase; BrdU; Bromodeoxyuridine; CaMKK; Calmodulin dependent protein Kinase Kinase; CRE; cAMP Response Element; EGF; Epidermal Growth Factor; HGF; Hepatocyte Growth Factor; HuR; Human-antigen R; IL-6; Interleukin-6; KO; Knock-O

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification, stability and expression of Sirt1 antisense long non-coding RNA

Keywords: چگونه; lncRNA; long noncoding RNA; Sirt1; Sirtuin 1; NATs; natural antisense transcripts; RBPs; RNA-binding proteins; miRNAs; microRNA; HuR; human antigen R; AS; antisense transcripts; UCH1; Ubiquitin Carboxyl-Terminal Esterase L1; Ptprj; Protein Tyrosine Phosph

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB

Keywords: چگونه; SASP, senescence-associated secretory phenotype; HuR, human antigen R; IL-6, interleukin 6; MEF, mouse embryonic fibroblast; sh-RNA, short hairpin RNA; DDR, DNA damage response; IR, ionizing radiation; UV, ultravioletSenescence; SASP; HuR; NF-κB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The PPARβ agonist L-165041 promotes VEGF mRNA stabilization in HPV18-harboring HeLa cells through a receptor-independent mechanism

Keywords: چگونه; ARE; AU-rich element; CHX; cycloheximide; ELAV; Embryonic Lethal Abnormal Vision; ERK1/2; Extracellular signal Regulated Kinase1/2; HPV; Human Papillomavirus; HuR; Human antigen R; MAPK; Mitogen-Activated Protein Kinase; mTOR; mammalian Target Of Rapamyci

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

5-Aminoimidazole-4-carboxamide ribonucleoside stabilizes low density lipoprotein receptor mRNA in hepatocytes via ERK-dependent HuR binding to an AU-rich element

Keywords: چگونه; LDL receptor; AICAR; HuR; ARE;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The epigenetic feedback loop between DNA methylation and microRNAs in fibrotic disease with an emphasis on DNA methyltransferases

Keywords: چگونه; miRNA; microRNA; DNMTs; DNA methyltransferases; HSC; hepatic stellate cell; IPF; idiopathic pulmonary fibrosis; RASAL; Ras GTPase activating-like protein; SOCS1; cytokine signaling-1 gene; PPARγ; peroxisome proliferator-activated receptor γ; MeCP2; meth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Post-transcriptional regulation of the human inducible nitric oxide synthase (iNOS) expression by the cytosolic poly(A)-binding protein (PABP)

Keywords: چگونه; 3′-UTR; 3′-untranslated region; 5′-UTR; 5′-untranslated region; AUF1; AU-rich element RNA binding protein 1; ARE; AU-rich element; ARE-BP; ARE binding protein; β2M; β2-microglobulin; β-tub.; β-tubulin; cds; coding sequence; CM; cytokine mixtur

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Retinoic acid-induced HOXA5 expression is co-regulated by HuR and miR-130a

Keywords: چگونه; HuR; miR-130a; HOXA5; Retinoic acid

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Cancer cell growth suppression by a 62nt AU-rich RNA from C/EBPβ 3′UTR through competitive binding with HuR

Keywords: چگونه; Distinct AU-rich RNA; C/EBPβ 3′UTR; Tumor suppression; HuR; Competitive binding;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression

Keywords: چگونه; ARE; AU-rich elements; COX-2; cyclooxygenase-2; eNOS; endothelial NO synthase; E2; 17β-estradiol; ER; estrogen receptor; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HO-1; heme oxygenase-1; HuR; Hu-antigen R; hPGT; human prostaglandin transporter; HU

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

HuR posttranscriptionally regulates early growth response-1 (Egr-1) expression at the early stage of T cell activation

Keywords: چگونه; 3′UTR; 3′-untranslated region; ARE; AU-rich element; ARE-BPs; ARE-binding proteins; Egr-1; early growth response-1; mRNP; messenger ribonucleoprotein; mRNP-IP; mRNP-immunoprecipitation; t1\2; half-life; Act D; actinomycin D; CHX; cycloheximide; HuR; E

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Posttranscriptional regulation of connexin-43 expression

Keywords: چگونه; Gap junctions; Connexin; RNA; miRNA; RNA binding proteins; HuR; Cx43;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

HuR post-transcriptionally regulates TNF-α-induced IL-6 expression in human pulmonary microvascular endothelial cells mainly via tristetraprolin

Keywords: چگونه; HuR; Tristetraprolin; IL-6; Human pulmonary microvascular endothelial cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

HuR-mediated posttranscriptional regulation of p21 is involved in the effect of Glycyrrhiza uralensis licorice aqueous extract on polyamine-depleted intestinal crypt cells proliferation

Keywords: چگونه; 3′F; a HuR-targeted sequence in p21 mRNA 3′-UTR; AREs; AU-rich elements; DAPI; 4′,6-diamidino-2-phenylindole; DFMO; alpha-difluoromethylornithine; CR; coding region; FCM; flow cytometry; GC; Gan Cao granules; GA; glycyrrhizic acid monoammonium salt;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Bile salts increase epithelial cell proliferation through HuR-induced c-Myc expression

Keywords: چگونه; Intestinal injury; Taurodeoxycholic acid (TDCA); c-Myc; HuR; Proliferation; Mucosal integrity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells

Keywords: چگونه; Chemoprevention; Colon Cancer; Oncogene; Tumor Suppressor; ACC; acetyl-CoA carboxylase; ADP; adenosine diphosphate; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; CRC; colorectal cancer; eIF4E; eukaryotic translatio

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Triptolide inhibits COX-2 expression by regulating mRNA stability in TNF-α-treated A549 cells

Keywords: چگونه; Triptolide; COX-2; mRNA stability; HuR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Organelles do not colocalize with mRNA granules in post-ischemic neurons

Keywords: چگونه; brain ischemia and reperfusion; hippocampus; HuR; mRNA granules; translation arrestAPRIL, acidic protein rich in leucine; ARE, adenine and uridine rich element; CA, Cornu Ammonis (Ammon's horn); COX IV, cytochrome c oxidase subunit IV; FISH, fluorescence

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه