Cancer cell growth suppression by a 62nt AU-rich RNA from C/EBPβ 3′UTR through competitive binding with HuR

► A 62nt RNA with AU-rich regions was isolated from the C/EBPβ 3′UTR. ► This 62nt RNA (R62) was introduced into a human hepatocarcinoma cell line. ► R62 suppressed cell growth rate and induced apoptosis. ► R62 specifically bound HuR. ► R62 competed with C/EBPβ mRNA for binding HuR.