Keywords: AAV; adeno-associated viruses; Ad6; adenovirus serotype 6; ABCB5Â +; ATP-binding cassette sub-family B member 5; ALDH; aldehyde dehydrogenase; AML; acute myeloid leukemia; APCs; antigen presenting cells; B7.1; (CD80) cluster of differentiation 80; BCG; Ba
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Comparative Expression of CD34, Intercellular Adhesion Molecule-1, and Podoplanin and the Presence of Mast Cells in Periapical Granulomas, Cysts, and Residual Cysts
Keywords: CD34; ICAM-1; mast cells; periapical cyst; periapical granuloma; podoplanin; residual cyst;
Bioavailable IGF-1 is beneficially associated with biomarkers of endothelial function in young healthy adults: The African-PREDICT study
Keywords: Vascular function; Youth; Age; Endothelial activation; Insulin-like growth factor-1; Insulin-like growth factor-binding protein-3; von Willebrand factor; Intercellular adhesion molecule-1; Vascular cell adhesion molecule-1; ABPM; ambulatory blood pressure
Histological and immunological characteristics of the junctional epithelium
Keywords: The junctional epithelium; Intraepithelial lymphocytes; ICAM-1; Cytokines; Chemokines; Enamel organ;
Anti-metastatic activity of Agrocybe aegerita galectin (AAL) in a mouse model of breast cancer lung metastasis
Keywords: Agrocybe aegerita galectin; Anti-metastatic activity; Apoptosis; ICAM-1; MMP9;
HaCaT epithelial cells as an innovative novel model of rhinovirus infection and impact of clarithromycin treatment on infection kinetics
Keywords: HaCaT; Epithelial cell line; Keratinocyte; Rhinovirus; ICAM-1; Clarithromycin;
C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential
Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;
The hydro-alcoholic extracts of Sardinian wild thistles (Onopordum spp.) inhibit TNFα-induced IL-8 secretion and NF-κB pathway in human gastric epithelial AGS cells
Keywords: IL-8; Interleukin 8; NF-κB; Nuclear factor κB; WHO; World Health Organization; TNFα; Tumor necrosis factor alpha;; IL-1β; Interleukin 1β; VCAM-1; Vascular cell adhesion protein 1; ICAM-1; Intercellular Adhesion Molecule 1; TNF-R1; Tumor necrosis fact
Fisetin inhibits the generation of inflammatory mediators in interleukin-1β-induced human lung epithelial cells by suppressing the NF-κB and ERK1/2 pathways
Keywords: Fisetin; Anti-inflammation; ICAM-1; COX-2; ERK1/2; NF-κB;
Attenuation of antimalarial agent hydroxychloroquine on TNF-α-induced endothelial inflammation
Keywords: HCQ; hydroxychloroquine; EC; endothelial cell; HUVEC; human umbilical-vein EC; TNF-α; tumor necrosis factor-α; PBMC; peripheral blood mononuclear cell; JNK; c-Jun N-terminal kinase; RA; rheumatoid arthritis; SLE; systemic lupus erythematosus; ICAM-1; in
Intravitreal administration of endothelin type A receptor or endothelin type B receptor antagonists attenuates hypertensive and diabetic retinopathy in rats
Keywords: Endothelin; Diabetes; Diabetic retinopathy; Retinal pigment epithelium; Hypertension; Vascular leakage; VEGF; BRB; blood-retinal barrier; BQ123; endothelin type A receptor antagonist; BQ788; endothelin type B receptor antagonist; Diab; diabetic; ET-1; end
A Yin and Yang in Epithelial Immunology: The Roles of the αE(CD103)β7 Integrin in T Cells
Keywords: CTL; cytotoxic T-lymphocyte; FoxP3; forkhead-box-P3; GvHD; graft-versus-host-disease; ICAM-1; intercellular adhesion molecule-1; LFA-1; lymphocyte function-associated antigen 1; TGF-β; transforming growth factor-β; Treg; regulatory T cell; TRM; resident
Ticagrelor, a P2Y12 antagonist, attenuates vascular dysfunction and inhibits atherogenesis in apolipoprotein-E-deficient mice
Keywords: Atherosclerosis; Inflammation; Endothelial function; P2Y12; Ticagrelor; Ach; acetylcholine; ACS; acute coronary syndrome; ADP; adenosine diphosphate; apoEâ/â; apolipoprotein E-deficient; Ctrl; control; HUVEC; human umbilical vein endothelial cell; ICA
Dietary n-3 but not n-6 fatty acids down-regulate maternal dyslipidemia induced inflammation: A three-generation study in rats
Keywords: Maternal dyslipidemia; n-3 fatty acids; n-6 fatty acids; Fetus; Inflammation; Offspring; ALA; α-linolenic acid; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HFL; high-fat lard; HFF; high-fat fish oil; HFC; high-fat canola oil; HFS; high-fat sun
Pharmacological effects and potential therapeutic targets of DT-13
Keywords: ADP; adenosine diphosphate; Akt; protein kinsase B; ALT; alanine transaminase; APD; action potential duration; AST; aspartate transaminase; Atg; autophagocytosis associated protein; CCR5; C, C chemokine receptor type 5; CXCR4; C-X-C chemokine receptor typ
Antitumor activity of Pinoresinol in vitro: Inducing apoptosis and inhibiting HepG2 invasion
Keywords: Pin; Pinoresinol; HepG2 cells; human hepatocellular carcinoma cell line; L02 cells; normal hepatocellular cell line; MMP; mitochondrial membrane potential; VCAM-1; vascular cell adhesion molecule-1; ICAM-1; intercellular cell adhesion molecule-1; MMP-9; m
Topical administration of reversible SAHH inhibitor ameliorates imiquimod-induced psoriasis-like skin lesions in mice via suppression of TNF-α/IFN-γ-induced inflammatory response in keratinocytes and T cell-derived IL-17
Keywords: SAHH; S-adenosyl-l-homocysteine hydrolase; IMQ; imiquimod; KC; keratinocytes; IL; interleukin; ICAM-1; intercellular adhesion molecule-1; EGFR; epidermal growth factor receptor; MAPKs; mitogen activated protein kinases; ERK; extracellular signal-regulated
Biomimetic nanoparticles for inflammation targeting
Keywords: apoE-/- mice; Apolipoprotein e knockout mice; CAM; cellular adhesion molecule; CCL5; chemokine (C-C motif) ligand 5; CD40L; cluster of differentiation 40 ligand; CTC; circulating tumor cell; CTL; cytotoxic T cell or CD8+ T cell; CXCL4; chemokine (C-X-
DNA methylation: A critical epigenetic mechanism underlying the detrimental effects of airborne particulate matter
Keywords: 5-mC; 5-methylcytosine; ACE; Angiotensin I converting enzyme; APEX; Apurinic/apyrimidinic endodeoxyribonuclease; BC; black carbon; CD40LG; CD40 ligand; EDN1; Endothelin 1; F3; coagulation factor III; Foxp3; Forkhead box protein 3; ICAM-1; Intercellular ad
Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment
Keywords: ACE2; angiotensin-converting enzyme-2; AGE; advanced glycation end-product; AT1R; angiotensin type 1 receptor; BMP; bone morphogenetic proteins; BMP-7; bone morphogenetic protein 7; CKD; chronic kidney diseases; Co-Smads; common mediator Smads; ECM; extra
Dysregulation of fibrosis related genes in HCV induced liver disease
Keywords: Alb; Albumin; ALK PH; Alkaline phosphatase; ALT; Alanine amino transferase; APO; Apolipoprotein; AST; Aspartate transaminase; AUC; Area Under Curve; BIL.D; Direct bilirubin; BIL T; Total bilirubin; BMI; Body mass index; cDNA; Complementary DNA; CTGF; Conn
Possible use of Punica granatum (Pomegranate) in cancer therapy
Keywords: 27HC; 27-hydroxycholesterol; 8-OHdG; 8-hydroxy-2â² -deoxyguanosine; 8-oxodG; 8-oxo-7,8-dihydro-2â²-deoxyguanosine; APC; adenomatous polyposis coli; AR; androgen receptors; AOM; azoxymethane; ATP; adenosine triphosphate; B(a)P; benzo(a)pyrene; Bad; Bcl-2
Kujigamberol interferes with pro-inflammatory cytokine-induced expression of and N-glycan modifications to cell adhesion molecules at different stages in human umbilical vein endothelial cells
Keywords: Kujigamberol; Pro-inflammatory cytokine; Interleukin-1α; ICAM-1; VCAM-1; E-selectin;
Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer
Keywords: Andrographolide; Andrographis paniculata; Diterpene lactone; Anticancer; Chemotherapy; Bioactive lactone; ACS; American Chemical Society; AKT; activated protein kinase; Andro; Andrographolide derivative or conjugate; AP-1; activator protein-1; Cdk; Cyclin
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
Treatment of β-thujaplicin counteracts di(2-ethylhexyl)phthalate (DEHP)-exposed vascular smooth muscle activation, inflammation and atherosclerosis progression
Keywords: β-thujaplicin; DEHP; Plasticizer; E-selectin; ICAM-1; VCAM-1; MMP-2; MMP-9;
Splenectomy had no significant impact on lipid metabolism and atherogenesis in Apoe deficient mice fed on a severe atherogenic diet
Keywords: TC; total cholesterol; LDL-C; low-density lipoprotein cholesterol; TG; triglycerides; FPLC; fast protein liquid chromatography; VLDL; very-low-density lipoprotein; IDL; intermediate-density lipoproteins; LDL; low-density lipoproteins; HDL; high-density li
Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice
Keywords: PND; Postoperative neurocognitive disorder; BBB; blood-brain barrier; NK-1R; neurokinin-1 receptor; CNS; central nervous system; SP; substance P; NK-1Ra; neurokinin-1 receptor antagonist; PBS; phosphate-buffered saline; ELISA; enzyme-linked immunosorbent
MicroSPECT imaging of triple negative breast cancer cell tumor xenografted in athymic mice with radioiodinated anti-ICAM-1 monoclonal antibody
Keywords: Radioiodination; SPECT; ICAM-1; Triple negative breast cancer;
Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis
Keywords: β-patchoulene; Pogostemon cablin; Indomethacin; Gastric ulcer; Antiulcer; β-PAE; β-patchoulene; CMC-Na; sodium carboxymethylcellulose; COX; cyclooxygenase; flt-1; fms-like tyrosine kinase-1; ICAM-1; intercellular adhesion molecule 1; JNK; c-Jun N-termi
CD18-mediated adhesion is required for the induction of a proinflammatory phenotype in lung epithelial cells by mononuclear cell-derived extracellular vesicles
Keywords: Extracellular vesicles; Integrins; Lung inflammation; Adhesion; CD18; ICAM-1;
HDAC inhibitors as epigenetic regulators for cancer immunotherapy
Keywords: AICD; activation-induced cell death; AML; acute myeloid leukemia; APC; antigen-presenting cells; CAR; coxsackie- and adenovirus receptor; CDKs; cyclin-dependent kinases; CG; cancer germline; DCs; dendritic cells; HAT; histone acetyltransferase; HDAC; hist
Tephrosin attenuates sepsis induced acute lung injury in rats by impeding expression of ICAM-1 and MIP-2
Keywords: Respiratory infection; Acute lung injury; Sepsis; Tephrosin; ICAM-1; MIP-2;
Inhibitory effect of Ligustrum vulgare leaf extract on the development of neuropathic pain in a streptozotocin-induced rat model of diabetes
Keywords: Ligustrum vulgare; Diabetic neuropathy; Hyperalgesia; Allodynia; Oleacein; 5-LOX; 5 - lipoxygenase; ACE; angiotensin converting enzyme; CCI; chronic constriction injury; COX-2; cyclooxygenase - 2; DPN; painful diabetic neuropathy; ICAM-1; intercellular ad
FOXOs in cancer immunity: Knowns and unknowns
Keywords: 2B4; CD244 molecule; AKT or PKB; protein kinase B; APCs; antigen-presenting cells; ARG1; arginase 1; BEC; blood endothelial cell; BLNK; B cell Linker protein; BMP; bone morphogenetic protein; BTK; Bruton tyrosine kinase; C/EBP; CCAAT/enhancer-binding prot
Constitutive DPP4 activity, inflammation, and microvascular reactivity in subjects with excess body weight and without diabetes
Keywords: ADA; American Diabetes Association; AUC; area uder the curve; BMI; body mass index; CD26; cluster of differentiation 26; DPP4; dipeptidyl peptidase 4; EDTA; ethylenediamine tetraacetic acid; FPG; fasting plasma glucose; GIP; glucose-dependent insulinotrop
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid
Keywords: Macrophage; Atherosclerosis; Myeloperoxidase; Oxidative stress; Inflammation; Cytokine; BSA; bovine serum albumin; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; HOCl; hypochlorous acid; HOSCN; hypothiocyanous acid; HUVEC; human umbilical vein endotheli
Anti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway
Keywords: Ang; angiopoietin; DR; diabetic retinopathy; EGF; epidermal growth factor; HCE; human corneal epithelium; HGF; hepatocyte growth factor; ICAM-1; intracellular adherent molecular-1; LCM; L cell conditioned medium; LRP5/6; low-density lipoprotein receptor-r
Hyperglycemia induced early growth response-1 regulates vascular dysfunction in human retinal endothelial cells
Keywords: Egr-1; early growth response-1; NGFI-A; nerve growth factor induced protein-A; NAB; NGFI-A binding protein; VEGF-A; vascular endothelial growth factor-A; PEDF; pigment epithelial derived factor; TF; tissue factor; ICAM-1; intercellular adhesion molecule-1
The SGK1 inhibitor EMD638683, prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation
Keywords: SGK1; serum-glucocorticoid regulated kinase 1; Ang II; Angiotension II; IL; interleukin; TGF-β; transforming growth factor-β; CTGF; connective tissue growth factor; TNF-α; tumor necrosis factor-α; IFN-γ; Interferon-γ; ASC; apoptosis associated speck
Cathepsin D enhances breast cancer invasion and metastasis through promoting hepsin ubiquitin-proteasome degradation
Keywords: CtsD; Hepsin; G2E3; ICAM-1; Breast cancer;
The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway
Keywords: WBGE; Inflammation; ICAM-1; miR-221/-222; PI3K/AKT; NF-κB; AKT; protein kinase B; C; Control; CH; charantin; COPD; chronic obstructive pulmonary disease; DMEM; Dulbecco's modified Eagle's medium; ERK; extracellular-signal-regulated kinase; ICAM; intercel
Contribution of lectin-like oxidized low-density lipoprotein receptor-1 and LOX-1 modulating compounds to vascular diseases
Keywords: LOX-1; Endothelial dysfunction; Atherosclerosis; Pharmacological therapy: microRNAs; ACE; angiotensin converting enzyme; Ang II; Angiotensin II; AT1R; angiotensin II receptor type 1; CCB; calcium channel blocker; CRP; C-reactive protein; eNOS; endothelial
Ethnopharmacology, phytochemistry, and pharmacology of Chinese Salvia species: A review
Keywords: ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AST; aspartate transaminase; CAT; catalase; CCL4; carbon tetrachloride; CK; casein kinase; DMN; dimethylnitrosamine; DPPH; 2,2-diphenyl-1-picrylhydrazyl; GSH; glutathione; HPRI; hepa
Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2
Keywords: 3-NT; 3-nitrotyrosine; 4-HNE; 4-hydroxynonenal; ACh; acetylcholine; AHR; aryl hydrocarbon receptor; ChIP; chromatin immunoprecipitation; c-NRF2; cytosolic NRF2; Ctrl; control; DM; diabetes mellitus; EC; endothelial cell; HDAC; histone deacetylase; HG; hig
ANGPTL-4 induces diabetic retinal inflammation by activating Profilin-1
Keywords: Diabetic retinopathy (DR); Angiopoietin-like protein-4 (ANGPTL-4); Profilin-1; Hypoxia inducible factor-1 alpha (HIF-1α); Inflammation; Adipocytokine; T2DM; type 2 diabetes mellitus; DR; diabetic retinopathy; PDR; proliferative diabetic retinopathy; HG;
The IL-6/STAT3 pathway regulates adhesion molecules and cytoskeleton of endothelial cells in thromboangiitis obliterans
Keywords: Ace-tubulin; acetylated-tubulin; ANOVA; analysis of variance; DAPI; 4â²,6-diamidino-2-phenylindole; C3; C3 transferase (RhoA inhibitor); ELISA; enzyme-linked immunosorbent assay; eNOS; endothelial nitric oxide synthase; FAK; focal adhesion kinase; FITC;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
CCL19-producing fibroblastic stromal cells restrain lung carcinoma growth by promoting local antitumor T-cell responses
Keywords: Lung inflammation; lung adenocarcinoma; fibroblastic reticular cells; tumor microenvironment; ADC; Adenocarcinoma; APC; Allophycocyanin; CAF; Cancer-associated fibroblast; DC; Dendritic cell; DT; Diphtheria toxin; ECM; Extracellular matrix; EpCAM; Epithel
Autoimmunity in multiple sclerosis: role of sphingolipids, invariant NKT cells and other immune elements in control of inflammation and neurodegeneration
Keywords: Ag; antigen; APC; antigen presenting cell; BBB; blood brain barrier; BCR; B cell receptor; BDNF; brain-derived neurotrophic factor; CIS; clinically isolated syndrome; CLR; C-type lectin receptor; CNS; central nervous system; CSF; cerebrospinal fluid; DAMP