Aberrant expression of Igf2/H19 in porcine parthenogenetic fetuses and placentas
Keywords: Pig; Parthenogenetic; H19; Igf2; Methylation
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Effect of IGF2 intron3-g.3072G>A on intramuscular fat (IMF) content in pigs raised in Poland
Keywords: IGF2; IMF; Meat quality; Pigs; Imprinting
The effects of two alleles of IGF2 on fat content in pig carcasses and pork
Keywords: IGF2; Fat content; Cured ham; Carcass conformation; Pig
Insulin-like growth factor system on adrenocortical tumorigenesis
Keywords: IGF system; IGF2; Beckwith–Wiedemann syndrome; IGF-1R; IGFBPs; Sporadic adrenocortical tumors
Differences in the molecular mechanisms of adrenocortical tumorigenesis between children and adults
Keywords: Adrenocortical tumors; Children; p53; IGF2; IGF1R; SF1
Patterns of deregulation of insulin growth factor signalling pathway in paediatric and adult gastrointestinal stromal tumours
Keywords: GIST; Gastrointestinal stromal tumour; IGF2; IGF1R;
Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke
Keywords: BMI; body mass index; CI; confidence interval; CpG; cytosine-phosphate-guanine dinucleotide pair; DMR; differentially methylated region; DNA; deoxyribonucleic acid; IGF2; insulin-like growth factor II; GED; general education development diploma; H19;
Insulin growth factor adjustment in preimplantation rabbit blastocysts and uterine tissues in response to maternal type 1 diabetes
Keywords: IGF1; IGF2; Exp IDD; Rabbit preimplantation embryo
Aberrant expression of imprinted genes and their regulatory network in cloned cattle
Keywords: Somatic cell nuclear transfer (SCNT); Cloned cattle; Developmental abnormality; Imprinting; IGF2;
Insulin-Like Growth Factor 2/H19 Methylation at Birth and Risk of Overweight and Obesity in Children
Keywords: BMI; Body mass index; CpG; Cytosine-phosphate-Guanine; DMR; Differentially methylated region; IGF2; Insulin-like growth factor 2; NEST; Newborn Epigenetics Study; WFA; Weight-for-age;
Sequences in the H19 ICR that are transcribed as small RNA in oocytes are dispensable for methylation imprinting in YAC transgenic mice
Keywords: CTCF; CCCTC-binding factor; DMR; differentially methylated region; Dnmt; DNA methyltransferases; ICR; imprinting control region; Igf2; insulin-like growth factor 2; miRNA; micro RNA; piRNA; PIWI-interacting RNA; siRNA; small interfering RNA; TgM; transgen
Adrenocortical stem and progenitor cells: Implications for adrenocortical carcinoma
Keywords: ACC, adrenocortical carcinoma; ACA, adrenocortical adenoma; ACT, adrenocortical tumor; FAdE, fetal adrenal enhancerStem cell; Adrenocortical carcinoma; Sf1; Hedgehog signaling; β-catenin; IGF2
Targeting the Insulin Growth Factor Receptor 1
Keywords: IGF1R; IGF1; IGF2; Insulin; Kinase; Cancer;
Notch Signaling Is Activated in Human Hepatocellular Carcinoma and Induces Tumor Formation in Mice
Keywords: Genetically Engineered Mouse Model; Notch Activation; Gene Expression Profiling; AFP; α-fetoprotein; GFP; green fluorescent protein; GSI; γ-secretase inhibitor; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; Igf2; insulin-like growth factor 2; I
Genetics and genomics of childhood adrenocortical tumors
Keywords: ACT; adrenocortical tumors; IGF2; Insulin-like Growth Factor-2; LFS; Li-Fraumeni syndrome; mTOR; mammalian Target Of Rapamycin; NOV/CCN3; Nephroblastoma OVerexpressed/CYR61-CTGF-NOV family member 3; SF1; Steroidogenic Factor-1; TP53; tumor protein 53; Adr
Coexpression of an intronic microRNA and its host gene reveals a potential role for miR-483-5p as an IGF2 partner
Keywords: Intronic miR-483; Igf2; Coexpression; Socs3
MiR-483-5p controls angiogenesis in vitro and targets serum response factor
Keywords: miRNA; Ischemic; Heart disease; IGF2; Angiogenesis; SRF
DNA methylation at H19/IGF2 ICR1 in the placenta of pregnancies conceived by in vitro fertilization and intracytoplasmic sperm injection
Keywords: DNA methylation; H19; ICR1; IGF2; placenta; IVF; ICSI; small for gestational age;
Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet
Keywords: Fetal Alcohol Syndrome; Ethanol teratogenesis; Igf2; DNA methylation; Methyl supplement
The hallmarks of CDKN1C (p57, KIP2) in cancer
Keywords: AML; acute myeloid leukemia; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-x long; BCR-ABL; breakpoint cluster region-V-abl Abelson murine leukemia viral oncogene homolog 1; bHLH; basic helix-loop-helix; BWS; Beckwith-Wiedemann Syndrome; CDK; cy
The Insulin-like Growth Factor Signaling Pathway as a Target for Treatment of Colorectal Carcinoma
Keywords: IGF1; IGF2; Phosphatidylinositol 3-kinase; Tyrosine kinase inhibitor
Decreased Placental Methylation at the H19/IGF2 Imprinting Control Region is Associated with Normotensive Intrauterine Growth Restriction but not Preeclampsia
Keywords: Methylation; IGF2; 11p15.5; H19; Placenta; IUGR; Imprinting; Preeclampsia
Hypomethylation of the IGF2 DMR in Colorectal Tumors, Detected by Bisulfite Pyrosequencing, Is Associated With Poor Prognosis
Keywords: Epigenetics; Clinical Outcome; Therapeutic Target; Imprinting Control Region; CI; confidence interval; CIMP; CpG island methylator phenotype; DMR; differentially methylated region; HR; hazard ratio; IGF2; insulin-like growth factor 2; LOI; loss of imprint
Mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) in carcinogenesis
Keywords: M6P/IGF2R; Loss of heterozygosity; Mutation; IGF2; Cancer
Placental Glycogen Stores are Increased in Mice with H19 Null Mutations but not in those with Insulin or IGF Type 1 Receptor Mutations
Keywords: Igf2; Glycogen; Growth; H19; Placenta
The ontogeny of genes related to ovine fetal cardiac growth
Keywords: Heart; Fetus; MR; GR; 11βHSD1; 11βHSD2; IGF1; IGF2; IGF1R; IGF2R; IGFBP2; ACE1; ACE2; AT1R; AT2R; Cortisol; Angiotensin; Angiotensinogen
Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle
Keywords: Imprinting; Methylation; IGF2; H19; SCNT; Bisulfite sequencing; Cloning; Cattle; Large offspring syndrome
Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma
Keywords: Methylation; Imprinting; IGF2; H19; Human hepatocellular carcinoma; Liver
A Review of the Role of Insulin-like Growth Factor 2 in Malignancy and its Potential as a Modifier of Radiation Sensitivity
Keywords: Clonogenic survival; IGF2; IGF1; IGF-1R; irradiation;
IGF2-driven PI3 kinase and TGFβ signaling pathways in chondrogenesis
Keywords: Chondrocytes; IGF2; PI3K; Akt; TGFβ; Aggrecan; Versican;
Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae
Keywords: Intrauterine growth restriction (IUGR); Small for gestational age (SGA); Imprinting; Placenta; IGF2; H19; KCNQ1OT1; CDKN1C; PHLDA2
Appropriate expression of imprinted genes on mouse chromosome 12 extends development of bi-maternal embryos to term
Keywords: H19; Igf2; Genomic imprinting; Development; Mouse
IGFBP3 Promoter Methylation in Colorectal Cancer: Relationship with Microsatellite Instability, CpG Island Methylator Phenotype, p53
Keywords: Colon cancer; IGFBP3; methylation; CIMP; MSI; BAX; BCL2-associated X protein; CACNA1G; calcium channel; voltagedependent; T type alpha-1G subunit; CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, CIP1); CDKN2A; cyclin-dependent kinase inhibitor 2A (p16,
The Expanding Role of Epigenetics in the Development, Diagnosis and Treatment of Prostate Cancer and Benign Prostatic Hyperplasia
Keywords: prostate; prostatic neoplasms; genetics; DNA methylation; chromatin; 5-AC; 5-aza-cytidine; BPH; benign prostatic hyperplasia; DAC; 5-aza-deoxycytidine; EGCG; (-)-epigallocatechin-3-gallate; HAT; histone acetyltransferase; HDAC; histone deacetylase; HDACi;
Loss of imprinting and promoter usage of the IGF2 in laryngeal squamous cell carcinoma
Keywords: IGF2; Laryngeal squamous cell carcinoma; Imprinting; Promoter usage;
IGF2 polymorphisms are associated with hepatitis B virus clearance and hepatocellular carcinoma
Keywords: IGF2; SNPs; Polymorphisms; Hepatitis B virus infection; Hepatocellular carcinoma; Haplotype; Association study
Allelic incidence in several pig breeds of a missense variant of pig melanocortin-4 receptor (MC4R) gene associated with carcass and productive traits; its relation to IGF2 genotype
Keywords: MC4R; Pig; RT-PCR; Composition; IGF2
The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA
Keywords: IGF2; Differentially methylated region; Cattle
Incidence in diverse pig populations of an IGF2 mutation with potential influence on meat quality and quantity: An assay based on real time PCR (RT-PCR)
Keywords: IGF2; Real time PCR; Iberian pigs; Selection;
Candidate genes associated with ageing and life expectancy in the Jerusalem longitudinal study
Keywords: Longevity; Polymorphisms; IGF2; Methylenetetrahydrofolate reductase; Apolipoprotein E; Superoxide dismutase; Angiotensinogen; Cathepsin D; Leiden factors V and VII; Dopamine D4 receptor; Serotonin transporter;
Genomic imprinting of IGF2, p57KIP2 and PEG1/MEST in a marsupial, the tammar wallaby
Keywords: Imprinting; Marsupial; IGF2; p57KIP2; PEG1/MEST; Yolk sac; Imprinting regulation; Placenta; Methylation;
Expression of bFGF and NGF and their receptors in chick's auditory organ following overexposure to noise
Keywords: bFGF; basic fibroblast growth factor; bFGFR; basic fibroblast growth factor receptor; aFGF; acidic fibroblast growth factor; NGF; nerve growth factor; NGFR; nerve growth factor receptor; BDNF; brain-derived neurotrophic factor; GDNF; glial-cell derived ne
Expression profiling with progression of dystrophic change in dysferlin-deficient mice (SJL)
Keywords: cDNA; complementary deoxyribonucleic acid; cRNA; complementary ribonucleic acid; CARP; cardiac ankyrin repeated protein; Cspg2; chondroitin sulfate proteoglycan 2; Cxcl; CXC chemokine ligand; EAE; experimental allergic encephalomyelitis; GTP; guanosine 5â