Interleukin (IL)-8 polymorphisms contribute in suicide behavior
Keywords: IL-8; Polymorphism; Suicide;
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Procalcitonin accurately predicts lung transplant adults with low risk of pulmonary graft dysfunction and intensive care mortality
Keywords: PCT; procalcitonin; IL-6; interleukin 6; IL-8; interleukin 8; IL-10; interleukin 10; AUC; area under the curve; CI; confidence interval; ICU; intensive care unit; LT; lung transplantation; LTr; lung transplantation recipient; CPB; cardiopulmonary bypass;
Transmissible gastroenteritis virus N protein causes endoplasmic reticulum stress, up-regulates interleukin-8 expression and its subcellular localization in the porcine intestinal epithelial cell
Keywords: ER; endoplasmic reticulum; IEC; intestinal epithelial cell line; IL-8; interleukin 8; N; nucleocapsid; ORFs; open reading frames; TGE; transmissible gastroenteritis virus; TGEV; TGE virus; UPR; unfolded-protein response; TGEV; N protein; Location; ER stre
Diagnosis of invasive aspergillosis in hematological malignancy patients: Performance of cytokines, Asp LFD, and Aspergillus PCR in same day blood and bronchoalveolar lavage samples
Keywords: Hematological malignancy; Aspergillus; Mold infection; Serum; BAL; IL-8; Mold-active antifungals; Galactomannan; Prophylaxis;
Effects of docosahexanoic acid supplementation on inflammatory and subcutaneous adipose tissue gene expression in HIV-infected patients on combination antiretroviral therapy (cART). A sub-study of a randomized, double-blind, placebo-controlled study
Keywords: Triglycerides; Docosahexanoic acid; Subcutaneous adipose tissue; IL-6; IL-8; TNF-α; PPAR-γ; MCP-1;
ShRNA-mediated knock-down of CXCL8 inhibits tumor growth in colorectal liver metastasis
Keywords: CXCL8; IL-8; Colorectal cancer; Invasion front; Liver metastasis; CXC chemokines; CXCR2;
LPS-induces IL-6 and IL-8 gene expression in bovine endometrial cells “through DNA methylation”
Keywords: LPS; Lipopolysaccharide; TLR4; Toll-Like Receptor 4; IL-6; interleukin 6; IL-8; interleukin 8; MeCP2; methyl CpG-binding protein 2; ELISA; Enzyme-linked immunosorbent assay; qRT-PCR; RNA extraction and quantitative real-time PCR; cDNA; complementary DNA;
The hydro-alcoholic extracts of Sardinian wild thistles (Onopordum spp.) inhibit TNFα-induced IL-8 secretion and NF-κB pathway in human gastric epithelial AGS cells
Keywords: IL-8; Interleukin 8; NF-κB; Nuclear factor κB; WHO; World Health Organization; TNFα; Tumor necrosis factor alpha;; IL-1β; Interleukin 1β; VCAM-1; Vascular cell adhesion protein 1; ICAM-1; Intercellular Adhesion Molecule 1; TNF-R1; Tumor necrosis fact
Screening probiotics from Lactobacillus strains according to their abilities to inhibit pathogen adhesion and induction of pro-inflammatory cytokine IL-8
Keywords: Lactobacillus; adhesion; inflammatory; IL-8;
Fisetin inhibits TNF-α/NF-κB-induced IL-8 expression by targeting PKCδ in human airway epithelial cells
Keywords: COPD; chronic obstructive pulmonary disease; ELISA; enzyme-linked immunosorbent assay; GM; growth medium; IKK; IκB kinase; PKC; protein kinase C; RT-PCR; reverse transcription-polymerase chain reaction; TNF-α; tumour necrosis factor-α; TNF-R1; TNF-α-r
Vibrio cholerae OmpU induces IL-8 expression in human intestinal epithelial cells
Keywords: Vibrio cholerae; OmpU; IL-8; Adherence; Inflammation; Intestinal epithelial cells;
A combination of NMR and liquid chromatography to characterize the protective effects of Rhus tripartita extracts on ethanol-induced toxicity and inflammation on intestinal cells
Keywords: ACP; acid phosphatase; ALP; alkaline phosphatases; DMSO; dimethylsulfoxide; EGCG; epigallocatechin-3-gallate; GIT; gastrointestinal tract; GST; glutathione-S-transferase; IL-8; interleukin 8; MTT; 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium brom
Let-7b ameliorates Crohn's disease-associated adherent-invasive E coli induced intestinal inflammation via modulating Toll-Like Receptor 4 expression in intestinal epithelial cells
Keywords: CD; Crohn's disease; AIEC; adherent-invasive E coli; TLR4; toll-like receptor 4; LPS; lipopolysaccharide; IECs; intestinal epithelial cells; WT; wild type; IL-10 KO; interleukin-10 knockout; SPF; specific pathogen free; TNF-α; tumor necrosis factor-α;
Clioquinol increases the expression of interleukin-8 by down-regulating GATA-2 and GATA-3
Keywords: Clioquinol; SMON; IL-8; GATA-2; GATA-3;
Halofuginone attenuates intervertebral discs degeneration by suppressing collagen I production and inactivating TGFβ and NF-кB pathway
Keywords: IVD; intervertebral discs; ECM; extracellular matrix; TGFβ; transform growth factor-β; NF-κB; nuclear factor of kappa b; IL-1β; interleukin 1β; IL-6; interleukin 6; IL-8; interleukin 8; NP; nucleus pulpous; AF; annulus fibrosus; CEPs; cartilaginous e
Immune and metabolic alterations in first episode psychosis (FEP) patients
Keywords: FEP; Cytokines and chemokines; Metabolic markers; IL-8; MIP-1b/CCL4; Ghrelin; Glucagon; VEGF; GLP-1;
Selective killing of proinflammatory synovial fibroblasts via activation of transient receptor potential ankyrin (TRPA1)
Keywords: RA; rheumatoid arthritis; WIN; WIN55212-2 mesylate ((R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone mesylate); TNF; tumor necrosis factor; IL-6; interleukin-6; IL-8; interleukin-8; TRPV1;
Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling
Keywords: CSC; cancer stem cell; SFC; sphere-forming cell; OCSC; ovarian cancer stem cell; OCSLC; ovarian cancer stem-like cell; TME; tumor microenvironment; ECM; extracellular matrix; TAM; tumor-associated macrophage; CM; conditional medium; OCSLC-CM; conditional
Genistein reduces proliferation of EP3-expressing melanoma cells through inhibition of PGE2-induced IL-8 expression
Keywords: Genistein; Melanoma; IL-8; PGE2; EP receptors;
Acute extracellular matrix, inflammatory and MAPK response to lengthening contractions in elderly human skeletal muscle
Keywords: LC; lengthening contractions; ECM; extracellular matrix; TGF-β; transforming growth factor-beta; TGF-βRII; transforming growth factor-beta receptor II; SMAD; Mothers against decapentaplegic homolog; MAPK; mitogen activated protein kinase; JNK; c-Jun N-t
Central nervous system diseases and Scutellaria: a review of current mechanism studies
Keywords: MMP-2 and MMP-9; matrix metalloproteinases; VEGF; vascular endothelial growth factor; NF-κB; nuclear factor-kappa B; HO-1; heme oxygenase-1; Nrf2; nuclear factor erythroid 2-related factor; INOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2;
Topically applied azaphenothiazines inhibit experimental psoriasis in mice
Keywords: TNF α; tumor necrosis factor α; IL; interleukin; LPS; lipopolysaccharide; IMQ; imiquimod; KERTr; human skin keratinocyte cell line; CXCL; C-X-C motif ligand; poly(I:C); polyinosinic:polycytidylic acid; LF; lipofectamine; Psoriasis; Mice; Azaphenothiazin
Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure
Keywords: CSE; Cigarette Smoke Extract; ChAT; choline acetyltransferase; ACh; acetylcholine; mAChRs; Muscarinic Acetylcholine receptors; β2ARs; β2 Adrenergic receptors; PEBP1; phosphatidylethanolamine binding protein 1; ROS; Reactive oxigen species; NOX-4; NADPH
TNIP1 reduction sensitizes keratinocytes to post-receptor signalling following exposure to TLR agonists
Keywords: TLR; toll-like receptor; TNIP1; tumor necrosis factor (TNF) α-induced protein 3-interacting protein 1; JNK; Jun-amino-terminal kinase; ABIN-1; A20-binding inhibitor of NF-κB activation; NF-κB; nuclear factor of enhancer of immunoglobulin kappa light-ch
Anti-inflammatory effects of isorhamnetin on LPS-stimulated human gingival fibroblasts by activating Nrf2 signaling pathway
Keywords: Isorhamnetin; LPS; Human gingival fibroblasts; IL-8; Nrf2;
Is it the time to study air pollution effects under environmental conditions? A case study to support the shift of in vitro toxicology from the bench to the field
Keywords: Air pollution; In vitro environmental exposure; Air liquid interface; Ultrafine particles toxicology; Secondary aerosol; Correlation PM-Composition and biological effects; AAE; Absorption Ã
ngström Angstrom Exponent; BC; black carbon; Dmed; median diame
NF-κB pathways in the development and progression of colorectal cancer
Keywords: 5-FU; 5-fluorouracil; AMPK/mTOR; AMP-activated Protein Kinase/mammalian target of rapamycin; APC; adenomatous polyposis coli; BAFF; B-cell activating factor; COX-2; cyclooxygenase 2; CRC; Colorectal cancer; DD; Dimerization domain; EGFR; epidermal growth
Molecular and functional characterization of tumor-induced factor (TIF): Hamster homolog of CXCL3 (GROγ) displays tumor suppressive activity
Keywords: CXCL1; CXCL3; CXCR2; GRO; IL-8; MAS; Tumor-induced factor; Chemokine; Ab; antibody; CHO-K1; Chinese hamster ovary-K1; CNV; copy number variation; CXCR2; CXC chemokine receptor 2; CRE; cAMP-response elements; DCIP1; dendritic cell inflammatory protein 1; D
Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R
Keywords: APC; allophycocyaninin; AU; arbitrary units; BSA; bovine serum albumin; C5aR; complement fragment 5a receptor; CI; confidence interval; Cmp1; Compound 1; CTAB; Hexadecyltrimethylammonium bromide; DMSO; dimethyl sulfoxide; FCS; fetal calf serum; FFAs; free
Anti-proliferative and anti-migratory effects of hyperforin in 2D and 3D artificial constructs of human dermal fibroblasts - A new option for hypertrophic scar treatment?
Keywords: HYP; hyperforin; Il-8; interleukine 8; HDF; human dermal fibroblasts; DMSO; dimethyl sulfoxide; AD construct; artificial dermal construct; Hyperforin; Human dermal fibroblast; Migration; Contraction; Skin; Viability assay; Live-dead cell staining;
The presence of IL-8 +781 T/C polymorphism is associated with the parameters of severe Clostridium difficile infection
Keywords: Clostridium difficile; Gene polymorphism; Interleukin 1β; Interleukin 8; Recurrence; CDI; Clostridium difficile infection; CRP; C reactive protein; EAEC; enteroaggregative form of Escherichia coli; GF; genotype frequencies; GFR; glomerular infiltration r
Sirt1 alleviates LPS induced inflammation of periodontal ligament fibroblasts via downregulation of TLR4
Keywords: Sirt1; Sirtuin1; PLF; periodontal ligament fibroblasts; LPS; lipopolysaccharide; IL-1α; interleukin-1α; IL-6; interleukin-6; IL-8; interleukin-8; TNF-α; tumor necrosis factor-α; TLR4; toll-like receptor 4; JNK/NF-κB; c-Jun N-terminal kinase/nuclear f
Serum levels of advanced glycation end-products (AGEs) and the decoy soluble receptor for AGEs (sRAGE) can identify non-alcoholic fatty liver disease in age-, sex- and BMI-matched normo-glycemic adults
Keywords: AGEs; advanced glycation end products; ALT; alanine aminotransferase; AST; aspartate aminotransferase; AUC; area under the curve; BMI; body mass index; CEL; Nε-carboxyethyl-L-lysine; CML; Nε-carboxymethyl-L-lysine; CML-d2; Nε-carboxy[2H2]methyl-L-lysin
Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation
Keywords: Myelodysplastic syndromes; NF-kB; Toll-like receptors; TNF-α; IL-8;
Cryopreservation of human whole blood allows immunophenotyping by flow cytometry up to 30Â days after cell isolation
Keywords: ANOVA; analysis of variance; BUMED; Bureau of Medicine and Surgery; CRADA; Cooperative Research and Development Agreement; d0; day 0; d5; day 5; d15; day 15; d30; day 30; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; FC; flow cytometry; FMO; fluoresc
Cross-talk between EGFR and IL-6 drives oncogenic signaling and offers therapeutic opportunities in cancer
Keywords: EGFR; epidermal growth factor receptor; IL-6; interleukin 6; ADC; antibody-drug conjugate; HGF; hepatocyte growth factor; c-met/MET; tyrosine-protein kinase Met; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; VEGF; vascular endothelial growth factor
Structural characterization and immunomodulatory activity of a pectic polysaccharide (CALB-4) from Fructus aurantii
Keywords: TCM; traditional Chinese medicine; PBMCs; human peripheral blood mononuclear cells; GC-MS; gas chromatography-mass spectrometry; IR; infrared spectroscopy; SEM; scanning electron microscopy; MAPKs; mitogen-activated protein kinases; TNF-α; tumor necr
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid
Keywords: Macrophage; Atherosclerosis; Myeloperoxidase; Oxidative stress; Inflammation; Cytokine; BSA; bovine serum albumin; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; HOCl; hypochlorous acid; HOSCN; hypothiocyanous acid; HUVEC; human umbilical vein endotheli
Non-thermal atmospheric pressure plasma-induced IL-8 expression is regulated via intracellular K+ loss and subsequent ERK activation in human keratinocyte HaCaT cells
Keywords: Non-thermal atmospheric pressure plasma; Keratinocyte; IL-8; Potassium; ERK;
Prevalence of the Helicobacter pylori homA and homB genes and their correlation with histological parameters in children
Keywords: Helicobacter pylori; homA gene; homB gene; Virulence genes; Children; Gastritis; PUD; peptic ulcer disease; GC; gastric cancer; MALT; mucosa-associated lymphoid tissue; OMP; outer membrane protein; IL-8; interleukin-8; cag-PAI; cagA pathogenicity island;
Response of intestinal HT-29 cells to the trichothecene mycotoxin deoxynivalenol and its sulfated conjugates
Keywords: DON; deoxynivalenol; DON-3-Sulf; deoxynivalenol-3-sulfate; DON-15-Sulf; deoxynivalenol-15-sulfate; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; Keap-1; kelch-like ECH-associated protein 1; Nrf-2; nuclear factor (erythroid-derived 2)-like 2; γ-GCL; ga
Gastroprotective effects of Hwanglyeonhaedok-tang against Helicobacter pylori-induced gastric cell injury
Keywords: HHT; Hwanglyeonhaedok-tang; OAC; omeprazole + amoxicillin + clarithromycin; TNF-α; tumor necrosis factor alpha; IL; interleukin; COX-2; cyclooxygenase 2; iNOS; inducible nitric oxide synthase; NF-κB; nuclear factor-kappa B; MAPK; mitogen-activated prote
Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation
Keywords: ABAH; 4-aminobenzoic acid hydrazide; ANCA; anti-neutrophil cytoplasmic antibody; ATP6; mitochondrial membrane ATP synthase; CYTB; cytochrome b; ETs; extracellular traps; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; granulocyte-macrophage colon
The beclomethasone anti-inflammatory effect occurs in cell/mediator-dependent manner and is additively enhanced by formoterol: NFkB, p38, PKA analysis
Keywords: Respiratory diseases; Inflammation; β2-agonists; Corticosteroids; Human endothelial cells; Bronchial epithelial cells; Adhesion molecules; IL-8; Intracellular signaling pathways;
Phosphosulindac is efficacious in an improved concanavalin A-based rabbit model of chronic dry eye disease
Keywords: BSA; bovine serum albumin; Con A; concanavalin A; DED; dry eye disease; ELISA; enzyme-linked immunosorbent assay; EMSA; electrophoretic mobility shift assay; ERK; extracellular signal-regulated kinase; IC50; half-maximal inhibitory concentration; IL-1β;
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Genetics of immunoglobulin-A vasculitis (Henoch-Schönlein purpura): An updated review
Keywords: AAV; antineutrophil cytoplasmic antibody associated vasculitis; ACE; angiotensin-converting enzyme; Agt; angiotensin; ANCA; antineutrophil cytoplasmic antibody; AT1R; angiotensin II receptor type 1; AT2R; angiotensin II receptor type 2; CCL2; chemokine C-
Effect of curcumin on expressions of NF-κBp65, TNF-α and IL-8 in placental tissue of premature birth of infected mice
Keywords: Curcumin; Premature birth induced with infection; LPS; NF-κBp65; TNF-α; IL-8;
The expression and correlation of Hsp 70 and Hsp 27 in serous middle ear effusion fluids of pediatric patients-a preliminary study
Keywords: Hsp 70; Hsp 27; Middle ear effusion; Otitis media with effusion; IL-8;