Keywords: در غربالگری سیلیکا; Trehalose synthase; Metagenome; Sequence-based screening; in silico screening; Micrococcus terreus; Thermobaculum terrenum;
مقالات ISI در غربالگری سیلیکا (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: در غربالگری سیلیکا; Brassinolide; Brassinosteroids; Rice lamina inclination; In silico screening; Pharmacophore
Keywords: در غربالگری سیلیکا; Prion; Drug discovery; In silico screening; Small chemical compounds; Conformational disorders
Keywords: در غربالگری سیلیکا; Quantitative structure-activity relationship (QSAR); Enhanced replacement method; In silico screening; Absorption, distribution, metabolism, excretion and toxicity (ADMET) studies; Design of histamine H3 antagonists;
Keywords: در غربالگری سیلیکا; MD, molecular dynamics; CPD, computational protein design; YFP, yellow fluorescent protein; FRET, Förster resonance energy transfer; rmsf, root-mean-square fluctuationmolecular dynamics; computational protein design; in silico screening; homodimer; domain
Keywords: در غربالگری سیلیکا; Atomistic simulation; In silico screening; High-throughput docking; Bromodomains; Tyrosine kinases; Proteases
Keywords: در غربالگری سیلیکا; Cell-penetrating peptides; Arginine-rich peptides; In silico screening; Macropinocytosis; Uptake efficiency; Intracellular delivery
Keywords: در غربالگری سیلیکا; Serine racemase inhibitors; NMDA receptor; In silico screening; d-Serine; Overactivation;
Keywords: در غربالگری سیلیکا; Structure-based drug design; In silico screening; Chitinase; Inhibitor; Asthma medications;
Keywords: در غربالگری سیلیکا; ERK2, extra-cellular signal-regulated kinase 2; STAT3, hepatic signal transducer and activator of transcription 3; 5-IOD, 5′-iodotubercidin; PEP, designed peptide inhibitor; pNA, p-nitroanilineERK2; Allosteric inhibitor; In silico screening; Crystal struc
In silico analysis and molecular docking study of angiotensin I-converting enzyme inhibitory peptides from smooth-hound viscera protein hydrolysates fractionated by ultrafiltration
Keywords: در غربالگری سیلیکا; In silico screening; Smooth-hound viscera; ACE-inhibitory peptides; Ultra-filtration; Molecular docking;
Exploration of DPP-IV inhibitors with a novel scaffold by multistep in silico screening
Keywords: در غربالگری سیلیکا; In silico screening; DPP-IV; Inhibitor; 3D-QSAR; Discriminant;
Discovery of a non-nucleoside RNA polymerase inhibitor for blocking Zika virus replication through in silico screening
Keywords: در غربالگری سیلیکا; In silico screening; Zika virus (ZIKV); RNA-dependent-RNA polymerase (RdRp); Non-nucleoside inhibitor (NNI); TPB;
Identification and validation of small molecule modulators of the NusB-NusE interaction
Keywords: در غربالگری سیلیکا; Protein-protein interaction; NusB-NusE; Antibiotic; Pharmacophore; In silico screening;
Structure-activity relationship-based screening of antibiotics against Gram-negative Acinetobacter baumannii
Keywords: در غربالگری سیلیکا; KAS; Fatty acid synthesis; Antibiotics; In silico screening; Gram-negative bacteria;
Novel anti-prostate cancer scaffold identified by the combination of in silico and cell-based assays targeting the PI3K-AKT-mTOR pathway
Keywords: در غربالگری سیلیکا; AKT; protein kinase B; AR; androgen receptor; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol-3-kinase; S6; ribosomal protein S6 kinase; SAR; structureactivity relationship; SBVS; structure-based virtual screening; In silico screening; Pro
Computational design and synthesis of novel fluoro-analogs of combretastatins A-4 and A-1
Keywords: در غربالگری سیلیکا; Combretastatin A-4 and A-1; Anticancer agent; Vascular disrupting agent; Fluoro-analog; Structure-based drug design; In silico screening; Structure-activity relationship;
Multi-step virtual screening to develop selective DYRK1A inhibitors
Keywords: در غربالگری سیلیکا; DYRK1A; Kinase selectivity; In silico screening; Free energy decomposition; Discriminant analysis;
Identification of SENP1 inhibitors through in silico screening and rational drug design
Keywords: در غربالگری سیلیکا; SENP1 inhibitor; In silico screening; Rational design; CancerSUMO, small ubiquitin-related modifier; SENP, SUMO-specific protease; pre-SUMO, SUMO precursor; E1, SUMO-activating enzyme; E2, SUMO-conjugation enzyme; E3, SUMO protein ligase; VEGF, vascular e
Bayesian models trained with HTS data for predicting β-haematin inhibition and in vitro antimalarial activity
Keywords: در غربالگری سیلیکا; Malaria; Antimalarial; Haemozoin; β-Haematin; In silico screening; Bayesian statistics; Machine learning;
Identification of protein kinase CK2 inhibitors using solvent dipole ordering virtual screening
Keywords: در غربالگری سیلیکا; Protein kinase CK2; In silico screening; Molecular similarity; Solvent dipole ordering; Kinase inhibitor; CK2; protein kinase CK2; TBB; 4,5,6,7-tetrabromo-1H-benzotriazole; IQA; [5-oxo-5,6-dihydroindolo(1,2-a)quinazolin-7-yl]acetic acid; DRB; 5,6-dichloro
Discovery of new human epidermal growth factor receptor-2 (HER2) inhibitors for potential use as anticancer agents via ligand-based pharmacophore modeling
Keywords: در غربالگری سیلیکا; Human epidermal growth factor receptor-2 (HER2); Pharmacophore modeling; Quantitative structure–activity relationship (QSAR); In silico screening
Anti-leprosy drug clofazimine inhibits growth of triple-negative breast cancer cells via inhibition of canonical Wnt signaling
Keywords: در غربالگری سیلیکا; Wnt signaling; Clofazimine; In silico screening; Breast cancer
Structure-based design of HSPA5 inhibitors: From peptide to small molecule inhibitors
Keywords: در غربالگری سیلیکا; Cancer; HSP70 inhibitors; In silico screening; Peptide substrate; Apoptosis;
An in silico virtual screening study for the design of norovirus inhibitors: fragment-based molecular docking and binding free energy calculations
Keywords: در غربالگری سیلیکا; Carbohydrate antigen; Influenza; Caliciviridae; In silico screening; Scoring function; Ro3
Elaborate ligand-based modeling reveal new migration inhibitory factor inhibitors
Keywords: در غربالگری سیلیکا; Migration inhibitory factor; Pharmacophore modeling; Quantitative structure–activity relationship; In silico screening
In silico approach to evaluate molecular interaction between mycotoxins and the estrogen receptors ligand binding domain: A case study on zearalenone and its metabolites
Keywords: در غربالگری سیلیکا; Food safety; Molecular modeling; Toxins; Zearalenone; In silico screening
Discovery of novel selective inhibitors of Staphylococcus aureus β-ketoacyl acyl carrier protein synthase III
Keywords: در غربالگری سیلیکا; KAS; Fatty acid synthesis; Antibiotics; In silico screening; MRSAKAS III, β-Ketoacyl acyl carrier protein synthase III; ecKAS III, E. coli KAS III; saKAS III, S. aureus KAS III; efKAS III, E. faecalis KAS III; HBD, hydrogen bonding donor; HBA, hydrogen bo
Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain
Keywords: در غربالگری سیلیکا; α7 Receptor; nAChR; AChBP; Virtual screening; In silico screening; Docking; Cys-loop;
Identification of novel drug-resistant EGFR mutant inhibitors by in silico screening using comprehensive assessments of protein structures
Keywords: در غربالگری سیلیکا; Epidermal growth factor receptor; Drug resistant mutant; In silico screening; Docking parameter optimization;
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors
Keywords: در غربالگری سیلیکا; Triazole-based inhibitors; In silico screening; mPGES-1; 5-Lipoxygenase;
Elaborate ligand-based modeling and subsequent synthetic exploration unveil new nanomolar Ca2+/calmodulin-dependent protein kinase II inhibitory leads
Keywords: در غربالگری سیلیکا; Ca2+/calmodulin-dependent protein kinase II; CaMKIIδ; Pharmacophore modeling; Quantitative structure-activity relationship; In silico screening; Cardiovascular diseases; Triazine;
Ligand-based designing, in silico screening, and biological evaluation of new potent fructose-1,6-bisphosphatase (FBPase) inhibitors
Keywords: در غربالگری سیلیکا; Fructose-1,6-bisphosphatase; Pharmacophore modeling; Receiver operating characteristic (ROC); In silico screening
An inverse docking approach for identifying new potential anti-cancer targets
Keywords: در غربالگری سیلیکا; Inverse docking; In silico screening; Protein–ligand interactions; Molecular docking
Exploration of new scaffolds as potential MAO-A inhibitors using pharmacophore and 3D-QSAR based in silico screening
Keywords: در غربالگری سیلیکا; MAO-A inhibitors; 3D-QSAR; Docking; Pharmacophore; in silico screening
Discovery of a new type inhibitor of human glyoxalase I by myricetin-based 4-point pharmacophore
Keywords: در غربالگری سیلیکا; Glyoxalase I; Inhibitor; Pharmacophore modeling; In silico screening; Structure–activity relationship
Identification of new inhibitors of protein kinase R guided by statistical modeling
Keywords: در غربالگری سیلیکا; dsRNA, double-stranded RNA; PKR, dsRNA-activated protein kinase; IFN, interferon; eIF-2α, α subunit of eukaryotic translation initiation factor 2Protein kinase R; Kinase inhibitors; In silico screening; Statistical modeling
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Keywords: در غربالگری سیلیکا; Nicotinic acetylcholine receptors (nAChR); Acetylcholine binding protein (AChBP); Electrophysiology; In silico screening; Virtual screening; Docking; Crystallization; Ligand-gated ion channels (LGICs); Cys-loop receptors
Discovery of new nanomolar peroxisome proliferator-activated receptor γ activators via elaborate ligand-based modeling
Keywords: در غربالگری سیلیکا; Peroxisome Proliferator-activated receptor γ; Pharmacophore modeling; Quantitative structure-activity relationship; In silico screening; Type 2 diabetes mellitus;
Discovery of new renin inhibitory leads via sequential pharmacophore modeling, QSAR analysis, in silico screening and in vitro evaluation
Keywords: در غربالگری سیلیکا; Renin; Pharmacophore modeling; QSAR; In silico screening
Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads
Keywords: در غربالگری سیلیکا; Glycogen phosphorylase; Pharmacophore; QSAR; In silico screening; In vitro validation; Synthetic exploration;
An efficient computational method for screening functional SNPs in plants
Keywords: در غربالگری سیلیکا; Functional analysis; Computational; In silico screening; Waxy protein; Ns coding; Non-synonymous coding; UTRs; Untranslated regions; TF; Transcriptional factors; TFBS; Transcriptional factor binding site;
Discovery of novel CDK1 inhibitors by combining pharmacophore modeling, QSAR analysis and in silico screening followed by in vitro bioassay
Keywords: در غربالگری سیلیکا; CDK1; Cancer; Pharmacophore modeling; QSAR; Genetic algorithm; MLR; In silico screening
Pharmacophore and QSAR modeling of estrogen receptor β ligands and subsequent validation and in silico search for new hits
Keywords: در غربالگری سیلیکا; Estrogen receptor β; Pharmacophore modeling; QSAR; Docking; ROC; In silico screening
Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration
Keywords: در غربالگری سیلیکا; CETP inhibitors; In silico screening; Pharmacophore modeling; Quantitative Structure–activity relationship; Shape constraints; Receiver-operating characteristicCETP, Cholesteryl ester transfer protein; QSAR, quantitative structure–activity relationship; R
Antimicrobial natural products as β-ketoacyl-acyl carrier protein synthase III inhibitors
Keywords: در غربالگری سیلیکا; KAS; Flavonoid; Phloretin; Antibiotics; In silico screening
Design of oseltamivir analogs inhibiting neuraminidase of avian influenza virus H5N1
Keywords: در غربالگری سیلیکا; Avian influenza virus subtype H5N1; Neuraminidase inhibitors; Oseltamivir analogs; Computer-assisted combinatorial library design; In silico screening
Novel E. coli β-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics
Keywords: در غربالگری سیلیکا; KAS; Antibiotics; In silico screening; STD-NMR
Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening
Keywords: در غربالگری سیلیکا; In silico screening; EGFR; VEGFR; Tyrosine kinase inhibitor; Indenopyrazoles
In silico multi-filter screening approaches for developing novel β-secretase inhibitors
Keywords: در غربالگری سیلیکا; Drug design; In silico screening; β-Secretase; MM/PBSA; Computational alanine scanning; Ligand docking